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321
Acquisition of anoikis resistance in human osteosarcoma cells does not alter sensitivity to chemotherapeutic agents
Published 2005-04-01“…Suspension culture was established by placing cells in tissue culture wells coated with poly-HEMA. …”
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322
Computational Properties of the Hippocampus Increase the Efficiency of Goal-Directed Foraging through Hierarchical Reinforcement Learning
Published 2016-12-01“…We investigate this idea by implementing a computational MBRL framework that incorporates features inspired by computational properties of the hippocampus: a hierarchical representation of space, forward sweeps through future spatial trajectories, and context-driven remapping of place cells. We find that a hierarchical abstraction of space greatly reduces the computational load (mental effort) required for adaptation to changing environmental conditions, and allows efficient scaling to large problems. …”
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323
Interpreting the meaning of changes in hippocampal volume associated with vestibular loss
Published 2023-08-01“…The argument presented here rests on 3 tranches of evidence: (1) Cognitive deficits have been observed in humans even in the absence of HPC atrophy; (2) HPC atrophy has not been reported in animal studies following vestibular loss, despite cognitive deficits; and (3) Animal studies have shown that the interruption of the transmission of vestibular information to the HPC has immediate consequences for HPC place cells, far too quickly to be explained by HPC atrophy. …”
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324
A model of head direction and landmark coding in complex environments.
Published 2021-09-01“…The relationship between these abstract landmark bearing neurons and head direction cells is reminiscent of the relationship between place cells and grid cells. Their unimodal encoding is formed from visual inputs via a modified version of Oja's Subspace Algorithm. …”
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325
Disorganization of Oscillatory Activity in Animal Models of Schizophrenia
Published 2021-10-01“…Finally, we focus on phase precession, which is an oscillatory phenomenon whereby individual hippocampal place cells systematically advance their firing phase against the background theta oscillation. …”
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326
Spatial maps and oscillations in the healthy hippocampus of Octodon degus, a natural model of sporadic Alzheimer’s disease
Published 2022-05-01“…Our findings show similarities between the Octodon degus and laboratory rodents. First, place cells with characteristics similar to those found in rats and mice exist in the CA1 subfield of the Octodon degus. …”
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327
Brain oscillations in sport: toward EEG biomakers of performance
Published 2016-02-01“…The oscillations in the thalamo-cortical and hippocampal circuitry including the physiology of the place cells and the grid cells provide a frame of reference for the analysis of delta, theta, beta, alpha (incl.mu) and gamma oscillations recorded in the space field of human performance. …”
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328
Head direction maps remain stable despite grid map fragmentation
Published 2012-03-01“…Areas encoding space in the brain contain both representations of position (place cells and grid cells) and representations of azimuth (head direction cells). …”
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329
A computational model for preplay in the hippocampus
Published 2013-11-01“…In offline states, the temporal sequence in which place cells fire spikes correlates with the sequence of their place fields. …”
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330
Super-resolution immunohistochemistry study on CD4 and CD8 cells and the relation to macrophages in human cochlea
Published 2019-03-01“…Interaction between these different cells was easily observed with SR-SIM, showing closely placed cell bodies, and the processes from macrophages reaching out and touching the lymphocytes. …”
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331
A Neural Network Model of the Entorhinal Cortex and Hippocampus for Event-Order Memory Processing
Published 2022-01-01“…For retrieval, an impetus input internally generates the sequential activation of conjunctive cue–place cells toward the reward location. In the figure-eight maze task, the location of the reward was estimated by mind travel, irrespective of whether the reward is in the counterclockwise or distant clockwise route. …”
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332
Bio-electrosprayed human neural stem cells are viable and maintain their differentiation potential [version 2; peer review: 1 approved, 2 approved with reservations]
Published 2020-07-01“…It holds great potential as a tissue engineering tool as it can be used to place cells into specific patterns. As the human central nervous system (CNS) cannot be studied in vivo at the cellular and molecular level, in vitro CNS models are needed. …”
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333
Unsupervised Learning and Clustered Connectivity Enhance Reinforcement Learning in Spiking Neural Networks
Published 2021-03-01“…To partition an environment into discrete states, implementations in spiking neuronal networks typically rely on input architectures involving place cells or receptive fields specified ad hoc by the researcher. …”
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334
The role of additive neurogenesis and synaptic plasticity in a hippocampal memory model with grid-cell like input.
Published 2011-01-01“…Finally, we show that place cells can emerge and refine in a realistic manner in our model as a direct result of the sparsification performed by the dentate gyrus layer.…”
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335
How reduction of theta rhythm by medial septum inactivation may covary with disruption of entorhinal grid cell responses due to reduced cholinergic transmission
Published 2013-10-01“…The network theta rhythm has been associated with properties of spatial navigation, as has the firing of entorhinal grid cells and hippocampal place cells. Two recent studies reduced the theta rhythm by inactivating the medial septum (MS) and demonstrated a correlated reduction in the characteristic hexagonal spatial firing patterns of grid cells. …”
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336
The frequency of hippocampal theta rhythm is modulated on a circadian period and is entrained by food availability.
Published 2015-03-01“…While the encoding of the spatial and contextual components of memory have been extensively studied, how the hippocampus encodes temporal information, especially at long time intervals, is less well understood. The activity of place cells in hippocampus has previously been shown to be modulated at a circadian time-scale, entrained by a behavioral stimulus, but not entrained by light. …”
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337
Size Matters: How Scaling Affects the Interaction between Grid and Border Cells
Published 2017-07-01“…Many hippocampal cell types are characterized by a progressive increase in scale along the dorsal-to-ventral axis, such as in the cases of head-direction, grid and place cells. Also located in the medial entorhinal cortex (MEC), border cells would be expected to benefit from such scale modulations. …”
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338
Computational Streetscapes
Published 2016-09-01“…With assistance from computing, consideration of streetscapes now reaches across scales, from the neurological interactions that form among place cells in the brain up to informatics that afford real-time views of activity over whole urban spaces. …”
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339
Exploiting semantic information in a spiking neural SLAM system
Published 2023-07-01“…Furthermore, grid cells, place cells, and object vector cells are observed by this model. …”
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340
Medial septum regulates the hippocampal spatial representation
Published 2015-06-01“…Non-selective septal theta-burst stimulation resets the spiking of hippocampal theta cells, increases theta synchronization, entrains the spiking of hippocampal place cells, and tunes the spatial properties in a timing-dependent manner. …”
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