A systematic review and meta-analysis of patient data from the West Africa (2013–16) Ebola virus disease epidemic by Rojek, A, Salam, A, Ragotte, R, Liddiard, E, Elhussain, A, Carlqvist, A, Butler, M, Kayem, N, Castle, L, Odondi, L, Stepniewska, K, Horby, P

“…Clinical data standards and data capture platforms are urgently needed.…”

Hugoniot measurements utilizing in situ synchrotron X-ray radiation by Miller, D, Crum, R, Homel, M, Eakins, D, Chapman, D, Jonsson, J, Rutherford, M, Escuariza, E, Smith, L, Herbold, E, Lind, J, Akin, M

“…Here, traditional Hugoniot measurements using PDV are compared to dynamic x-ray imaging encompassing two different sample geometries on the gas gun platform. Through each of these methods an experimentally derived Hugoniot is determined for a previously uncharacterized polymeric material, Somos Watershed XC11122, that is used 3D printed stereolithography parts. …”

ASPASIA: A toolkit for evaluating the effects of biological interventions on SBML model behaviour by Evans, S, Alden, K, Cucurull-Sanchez, L, Larminie, C, Coles, M, Kullberg, M, Timmis, J

“…We present ASPASIA (Automated Simulation Parameter Alteration and SensItivity Analysis), a cross-platform, open-source Java toolkit that addresses a key deficiency in software tools for understanding the impact an intervention has on system behaviour for models specified in Systems Biology Markup Language (SBML). …”

Youth adversity and trajectories of depression/anxiety symptoms in adolescence in the context of intersectionality in the United Kingdom by Havers, L, Shuai, R, Fonagy, P, Fazel, M, Morgan, C, Fancourt, D, McCrone, P, Smuk, M, Bhui, KS, Shakoor, S, Hosang, GM

“…The current results provide a platform for further research, which is needed to determine the importance of intersectionality as a moderator of youth adversity on the development of depression and anxiety symptoms in adolescence.…”

The OxCM contour method solver for residual stress evaluation by Uzun, F, Korsunsky, AM

“…This paper introduces the OxCM contour method solver, a console application structured based on the legacy version of the FEniCS open-source computing platform for solving partial differential equations (PDEs) using the finite element method (FEM). …”

The schistosomiasis clinical trials landscape: A systematic review of antischistosomal treatment efficacy studies and a case for sharing individual participant-level data (IPD) by Julé, A, Vaillant, M, Lang, T, Guérin, P, Olliaro, P

“…Meta-data, i.e. study-level characteristics (Schistosoma species, number of patients, drug administered, country, etc.) and efficacy parameters were extracted from published documents to evaluate the scope of an individual-level data sharing platform.Out of 914 documents screened, 90 studies from 26 countries were included, enrolling 20,517 participants infected with Schistosoma spp. and treated with different PZQ regimens or other drugs. …”

Systematic review and meta-analysis of hypothermic machine perfusion versus static cold storage of kidney allografts on transplant outcomes. by O'Callaghan, J, Morgan, R, Knight, SR, Morris, P

“…METHODS: A literature search was performed using MEDLINE, Embase, the Cochrane Library, the Transplant Library and the International Clinical Trials Registry Platform. The final date for searches was 30 November 2012. …”

Metabolomics reveal alterations in arachidonic acid metabolism in Schistosoma mekongi after exposure to praziquantel by Chienwichai, P, Tipthara, P, Tarning, J, Limpanont, Y, Chusongsang, P, Chusongsang, Y, Adisakwattana, P, Reamtong, O

“…The metabolomic data for the treatment groups were analyzed with the XCMS online platform and compared with data for the no treatment group. …”

Wii-habilitation: is there a role in trauma? by Butler, D, Willett, K

“…It is now conceivable that computer-based rehabilitation programmes could be developed using current, widely available, affordable virtual reality platforms, such as the Nintendo® Wii. This review aims to discuss the use of modern computer technology in patient rehabilitation and how this may be applied to trauma patients. © 2009 Elsevier Ltd. …”

Immune responses to vaccines against malaria by Bliss, C

“…The assay demonstrated the ability of CD8⁺ T cells to inhibit parasite development in a TRAP-specific manner, and provides a platform with which to further explore pre-erythrocytic immune responses.…”

Direct RNA sequencing of respiratory syncytial virus infected human cells generates a detailed overview of RSV polycistronic mRNA and transcript abundance by Donovan-Banfield, I, Milligan, R, Hall, S, Gao, T, Murphy, E, Li, J, Shawli, GT, Hiscox, J, Zhuang, X, McKeating, JA, Fearns, R, Matthews, DA

“…Total RNA was harvested and polyadenylated mRNA was enriched and sequenced by direct RNA sequencing using an Oxford nanopore device. This platform yielded over 450,000 direct mRNA transcript reads which were mapped to the viral genome and analysed to determine the relative mRNA levels of viral genes using our in-house ORF-centric pipeline. …”

Mind the gap: Flânerie in Baudelaire and Woolf by Wang, S

“…The purpose of this thesis is to interrogate and reinterpret the notion of modernity: experience of modernity is that of spatiotemporal dislocation, a sense of in-betweenness that can be likened to the gap between a train and the platform. From the gap imagery, this thesis explores the paradoxical nature of modernity demonstrated in the writing of Baudelaire and Woolf. …”

Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study. by Orozco, G, Eyre, S, Hinks, A, Ke, X, Wilson, A, Bax, D, Morgan, A, Emery, P, Steer, S, Hocking, L, Reid, D, Wordsworth, P, Harrison, P, Thomson, W, Barton, A, Worthington, J

“…METHODS: A total of 4 SNPs (rs4810485 in CD40, rs2812378 in CCL21, rs42041 in CDK6 and rs6682654 in CD244) were genotyped in a UK cohort comprising 3962 UK patients with RA and 3531 healthy controls using the Sequenom iPlex platform. Genotype counts in patients and controls were analysed with the chi(2) test using Stata. …”

Imposing long-range ferromagnetic order in rare-earth doped magnetic topological-insulator heterostructures by Duffy, L, Frisk, A, Burn, D, Steinke, N, Herrero-Martin, J, Ernst, A, van der Laan, G, Hesjedal, T

“…Engineered magnetic TI heterostructures may be an ideal materials platform for observing the QAH effect at liquid He temperatures and above.…”

Imaging dynamic pore-formation processes in droplet-interface bilayers by Sengel, JT

“…</p> <p>This work presents droplet-interface bilayers (DIBs) as a platform for overcoming some of these challenges. The technique is in particular applied to the study of electroporation, a well-known and widely used but less comprehensively understood phenomenon in which transmembrane pores are generated under the influence of an applied electric field. …”

Demystifying informational public interest in the United States by Zhang, J

“…Telecommunications law and digital platform law embrace a hybrid version –– procedurally facilitating the whole process of information transmission and economically enhancing the competition in the marketplace. …”

Multi-modal people detection from aerial video by Flynn, H

“…Although there are regulatory issues involved in flying these that are still to be solved, they have the potential to provide a practical mobile aerial platform for a small fraction of the cost of a conventional manned helicopter. …”

Quantitative proteomics reveals CLR interactome in primary human cells by Manolis, D, Hasan, S, Maraveyas, A, O'Brien, DP, Kessler, BM, Kramer, H, Nikitenko, LL

“…Collectively, our study provides a first-of-its-kind integrative methodological approach and datasets as valuable resources and robust platform/springboard for advancing the discovery and comprehensive characterization of physiologically relevant CLR interactome at a proteome-wide level in a range of cell types and diseases in future studies.…”

The role of interfacial lipids in stabilising membrane protein oligomers by Gupta, K, Donlan, J, Hopper, J, Uzdavinys, P, Landreh, M, Struwe, W, Drew, D, Baldwin, A, Stansfeld, P, Robinson, C

“…Here we develop a mass spectrometry platform to determine simultaneously presence of interfacial lipids and oligomeric stability and discover how lipids act as key regulators of membrane protein association. …”

On the edge of a digital pathology transformation: Views from a cellular pathology laboratory focus group by Turnquist, C, Roberts-Gant, S, Hemsworth, H, White, K, Browning, L, Rees, G, Roskell, D, Verrill, C

“…With a few notable exceptions in the UK, few National Health Service (NHS) departments have deployed digital pathology platforms. Thus, in the next few years, many departments are anticipated to undergo the transition to digital pathology. …”