The influence of additives on the delivery of paclitaxel from bioresorbable PLGA films by Huang, Charlotte Liwen.

“…The objective is to investigate the use of additives as a means to control and modulate the delivery of paclitaxel from PLGA thin films. The release profiles obtained from the first part of the study with different types of PLGA show linear dependence on the concentration of terminal carboxylic acid end-groups of PLGA, which also regulates the degradation of PLGA films. …”
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Release retardation of model protein on polyelectrolyte-coated PLGA nano- and microparticles by Nugraha, Chandra, Bora, Meghali, Venkatraman, Subbu S.

“…Although liposomes have received considerable attention with PEM coating for sustained drug release, similar results employing PEM built on poly(lactic-co-lycolic acid) (PLGA) particles is scant. In this work, we demonstrate that the build-up pH and polyelectrolyte pairs of PEM affect the release retardation of BSA from PLGA particles. …”
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Mathematical modelling of PLGA degradation using deterministic population balance model by Yip, Jason Kong Wai.

“…The degradation of Poly(lactic-co-glycolic acid) ,PLGA is one such type of polymer that has been the focus of many recent studies. …”
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Functionally graded PLGA-nano apatite-lauric acid biocomposite membrance for potential clinical applications / by Jamuna Thevi Kalitheertha Thevar, 1976-, author 608039, Mohammed Rafiq Abdul Kadir, supervisor, 602938, Nik Ahmad Nizam Nik Malek, supervisor, 1982- 493865, Fakulti Biosains dan Kejuruteraan Perubatan

Functionally graded PLGA-nano apatite-lauric acid biocomposite membrance for potential clinical applications / by Jamuna Thevi Kalitheertha Thevar, 1976-, author 608039

Studies of degradable ureteric stents by Huang, Yun.

“…PLGA 80/20 tubes were soft but remained intact after 84 days. …”
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Novel on-demand bioadhesion to soft tissue in wet environments by Steele, Terry W. J., Mogal, Vishal, Papper, Vladislav, Chaurasia, Alok, Feng, Gao, Marks, Robert

“…The diazirine-modified PLGA thin films could be added on top of previously developed technologies for minimally invasive surgeries. …”
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Development of novel microparticles for diabetic wound healing by Chua, Isaiah Jia Qing

“…This report studies the use of tri-layered microparticles (chitosan/PLGA/PLLA) and dual-layered microparticles (PLGA/PLLA) to deliver three different drugs (DF/EGCG/SS) in sequential and sustained manner. …”
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Effect of size on degradation and different fabrication methods for nano particles by Loh, Eugenia Mei Ting.

“…Poly (lactic-co-glycolic acid), also known as PLGA, is commonly used to encapsulate drugs for drug delivery purpose in the form of micro size particles as well as nano order particles. …”
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Prolonged release of risperidone via gastro retentive drug delivery device by Kwan, Audrey Kai Xin

“…The polymeric microparticles made of PLGA and a polymeric blend of PLGA:PLLA (1:1) achieved 100% release of risperidone in-vitro within 21 days and 11 days respectively. …”
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Antimicrobial efficacy testing of antibiotic-containing biodegradable nanopolymers against biofilm and planktonic cells. by Polimyr Caesar Dave Pelisco Dingal.

“…For both pathogens, minimum inhibitory concentrations (MIC) of 2.8 µg/mL and 16.5 µg/mL total LEV load were found for LEV-PLGA and LEV-PCL, respectively. Minimum biofilm eradication concentrations (MBECs) improved at least 2-fold with increase in exposure time (48 hours) achieving LEV-PLGA MBECs of 1.4 and 0.2 µg/mL and LEV-PCL MBECs of 16.5 and 8.2 µg/mL for E. coli and P. aeruginosa, respectively. …”
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Instructive scaffolds for tissue engineering by Cham, Hui Ting

“…This is done by encapsulating the small molecules in poly(lactic-co-glycolic acid) (PLGA) microparticles and incubating them with THP-1 differentiated macrophages. …”
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Cytotoxic and genotoxic characterization of titanium dioxide, gadolinium oxide, and poly(lactic-co-glycolic acid) nanoparticles in human fibroblasts by Das, Gautom Kumar, Loo, Joachim Say Chye, Leong, David Tai, Ng, Kee Woei, Xiong, Sijing, Zhao, Xinxin, Setyawati, Magdiel Inggrid, Khoo, Pheng Kian Stella, Eng, Bao Hui, Tan, Timothy Thatt Yang

“…These two nanomaterials also promoted genotoxicity via DNA damage. On the contrary, PLGA nanoparticles did not induce significant cytotoxic or genotoxic effects on BJ cells.…”
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Percutaneous Intratumoral Immunoadjuvant Gel Increases the Abscopal Effect of Cryoablation for Checkpoint Inhibitor Resistant Cancer by Som, Avik, Rosenboom, Jan‐Georg, Wehrenberg‐Klee, Eric, Chandler, Alana, Ndakwah, Gabrielle, Chen, Eric, Suggs, Jack, Morimoto, Joshua, Kim, Jonathan, Mustafa, Abdul Rehman, Marcos‐Vidal, Asier, Fintelmann, Florian J., Basu, Arijit, Langer, Robert, Traverso, Giovanni, Mahmood, Umar

“…The poly‐lactic‐<jats:italic>co</jats:italic>‐glycolic acid‐polyethylene glycol‐poly‐lactic‐<jats:italic>co</jats:italic>‐glycolic acid (PLGA‐PEG‐PLGA)‐based amphiphilic copolymer gel's underlying micellar nature enables high drug concentration and a logarithmic release profile that is additive with the neo‐antigen release from cryoablation, requiring only a single injection. …”
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Release studies of naked DNA, polyplexes and lipoplexes from polymeric films by Ramgopal Yamini

“…The polymeric system studied includes PLGA (53/47), PCL and PEVAC .The release profile was determined by quantifying the amount of DNA released at specific time points over a period of 1 month, utilizing the fluorescence of ethidium bromide.The bioactivity of the released complexes were determined by in vitro cell transfection using COS 7 cells. …”
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Biodegradable post biopsy breast marker by Teh, Wen Hui

“…Prototypes were fabricated with varying composition of Poly (lactic-co-glycolic acid) (PLGA) (in molar ratio 50:50, 75:25 and 82:18) to impart timeframe of degradation in 3, 6 and 9 months and with embedded radiopaque fillers to enhance radiopacity under X-Ray imaging. …”
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Platelet activation studies on polymeric surfaces by Suzliana Sulaimi

“…Platelets were incubated on PLGA substrates with varying geometric aspects. …”
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On-Demand Bioadhesive Dendrimers with Reduced Cytotoxicity by Gao, Feng, Djordjevic, Ivan, Pokholenko, Oleksandr, Zhang, Haobo, Zhang, Junying, Steele, Terry W. J.

“…The in vivo immunological response to PAMAM-g-diazirine formulations was found to be optimal in comparison to standard poly(lactic-co-glycolic acid) (PLGA) thin films.…”
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Studies of injectable in situ depot-forming systems for drug delivery by Liu, Hui

“…These systems are composed of a biodegradable polymer poly(D,L-lactide) (PLA) or poly(D,L-lactide-co-glycolide) (PLGA) and a low Mw model drug in an organic solvent. …”
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Lipid-coated hybrid nanoparticles for enhanced bacterial biofilm penetration and antibiofilm efficacy by Lee, Hiang Wee, Kharel, Sharad, Loo, Joachim Say Chye

“…In this study, LCHNPs composed of a poly(lactic-co-glycolic acid) (PLGA) core and dioleoyl-3-trimethylammonium propane (DOTAP) lipid shell were developed and loaded with vancomycin (Van). …”
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