CYP450 and drug efflux transporters polymorphism influence clinical outcomes of Thai osimertinib-treated non-small cell lung cancer patients by Teerapat Majam, Teerapat Majam, Chonlaphat Sukasem, Chonlaphat Sukasem, Chonlaphat Sukasem, Chonlaphat Sukasem, Thanyanan Reungwetwattana, Phichai Chansriwong, Chalirmporn Atasilp, Narumol Trachu, Thanaporn Thamrongjirapat, Rattanaporn Sukprasong, Jennis Meanwatthana

“…Moreover, our study showed a higher incidence of ADRs than the previous trials, including FLAURA and AURA2, and a higher frequency of dose reduction than reported in the AURA 3 trial, possibly due to genetic differences among the study populations.…”
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Impacts et services environnementaux de l’élevage en régions chaudes by V. BLANFORT, M. DOREAU, J. HUGUENIN, J. LAZARD, V. PORPHYRE, J.F. SOUSSANA, B. TOUTAIN

“…Elles conditionnent l’amélioration des performances environnementales à la mise en place de systèmes d’élevage assurant la réponse aux besoins alimentaires des populations et la durabilité économique et sociale indispensable aux sociétés en développement. …”
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Cells Remain Viable When Collected With an In-Line-Suction Tissue Collector From Byproducts of Anterior Cruciate Ligament Reconstruction Surgery by Adam W. Anz, M.D., Joshua J. Cook, M.S., A.C.R.P.-P.M., C.C.R.C., Eric A. Branch, M.D., Charlkesha A. Rahming, M.S., Roger V. Ostrander, III, M.D., Steve E. Jordan, M.D.

“…All tissue samples were digested using collagenase, and the derived cellular populations were analyzed in vitro, characterizing cellular viability, proliferative potential, qualitative multipotent differentiation capacity, and cell-surface marker presence. …”
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Prevalence of aggressive care among patients with cancer near the end of life: a systematic review and meta-analysisResearch in context by Zhuo Ma, Huangqianyu Li, Yi Zhang, Lan Zhang, Guo Huang, Yichen Zhang, Luwen Shi, Wei Liu, Zhuoling An, Xiaodong Guan

“…Interpretation: This meta-analysis found that aggressive EOL care was common in patients with cancer, regardless of the definition used, and varied by regions and populations. It is necessary to be aware of the global burden of aggressive care for patients with cancer near their EOL and take prompt action to address it. …”
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Nonsurgical periodontal treatment during pregnancy and rates of preterm birthAJOG Global Reports at a Glance by Gregory C. Valentine, MD, MEd, FAAP, Krystle Perez, MD, MPH, Adino T. Tsegaye, MPH, Daniel A. Enquobahrie, MD, MPH, PhD, David Couper, PhD, James D. Beck, MS, PhD, Rachel Umoren, MBBCh, MS, Kjersti M. Aagaard, MD, PhD, Christy M. McKinney, PhD

“…Beyond periodontal disease, the risk of preterm birth varies both by previous history of preterm birth and in association with social determinants prevalent among vulnerable and marginalized populations. This study hypothesized that the timing of periodontal treatment during pregnancy and/or social vulnerability measures modified the response to dental scaling and root planing for the treatment of periodontitis and prevention of preterm birth. …”
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Application Of Raman Microscopy For The Diagnosis Of The Chronic Lymphocytic Leukemia (Cll) by M. Fere, L. H. Liu, C. Gobinet, A. Beljebbar, V. Untereiner, J.-F. Angiboust, M. Manfait, D. Gheldorf, H. Jacquemin, S. Walbrecq, E. Cornet, X. Troussard, B. Chatelain, J. Angelo, M. Chollat, J. Klossa, O. Piot

“…For the establishment of the Raman classifiers, this post-acquisition treatment was used as reference to distinguish the different lymphocyte sub-populations. Raman data were then analyzed using chemometric processing and supervised statistical classifiers in order to construct a spectral library of markers highly specific of the lymphocyte type and status (normal or pathological). …”
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Identification of a novel defined inflammation-related long noncoding RNA signature contributes to predicting prognosis and distinction between the cold and hot tumors in bladder c... by Xi Xiong, Chen Chen, Xinxin Li, Jun Yang, Wei Zhang, Xiong Wang, Hong Zhang, Min Peng, Lili Li, Pengcheng Luo

“…We also used package ggpubr to evaluate TME scores and immune checkpoint activation in LRS and HRS populations. R package GSEABase was used to analyze the activity of immune cells or immune function. …”
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ANÁLISIS DE RESISTENCIA INSULÍNICA, TOLERANCIA A LA GLUCOSA Y TESTOSTERONA EN MUJERES JÓVENES CON SÍNDROME DE OVARIO POLIQUÍSTICO AGRUPADAS POR ÍNDICE DE MASA CORPORAL by María José del Río V, Juan Pablo Ramírez M, Manuel E. Cortés, Gerardo Martí O, Ana Godoy R, Pilar Vigil P

“…The absence of correlation between total testosterone and the other variables, suggests that in PCOS multiple factors are involved and that this syndrome includes different sub-populations of patients that require a revised diagnosis. …”
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Safety and Efficacy of Metabolic Surgery in Patients with Type 2 Diabetes in the Middle East and North Africa Region: An Analysis of Primary Roux-en-Y Gastric Bypass and Sleeve Gas... by Sami Fares, Juan S. Barajas-Gamboa, Gabriel Díaz del Gobbo, Michael Klingler, Juan Pablo Pantoja, Carlos Abril, Javed Raza, Alfredo D. Guerron, Ricard Corcelles, Matthew Allemang, John Rodriguez, Matthew Kroh

“…Bariatric surgery has been demonstrated to be a safe and effective treatment for T2D in different populations worldwide, though few specific data exist on outcomes of procedures in the MENA region. …”
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Supplementation with food-derived oligopeptides promotes lipid metabolism in young male cyclists: a randomized controlled crossover trial by Aina Jin, Zhaobo Kan, Qiushi Tan, Jing Shao, Qi Han, Yashan Chang, Nan An, Muqing Yi

“…The findings of this study provide novel insight into strategies for promoting lipid metabolism in populations with dyslipidemia-related metabolic disorders such as obesity and for improving physiological functioning during endurance training. …”
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Le rôle clé de la pratique infirmière en contexte de changements climatiques by Audrey Lortie, Charles Bilodeau, Maude Roy, Amelia Joudcar, Lydia Tania Ziani

“…Ce résumé a pour objectifs d’identifier des actions permettant de sensibiliser et de former les membres de la profession infirmière aux enjeux climatiques et à leurs conséquences sur la santé des individus et des populations. Il vise également à encourager les infirmières et infirmiers à devenir des agents de changement dans la lutte contre les changements climatiques en mettant en lumière les travaux présentés par le Comité Jeunesse de l’Ordre des infirmières et infirmiers du Québec (2020). …”
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Mutations of TP53 and genes related to homologous recombination repair in breast cancer with germline BRCA1/2 mutations by Jinyong Kim, Kyeonghun Jeong, Hyeji Jun, Kwangsoo Kim, Jeong Mo Bae, Myung Geun Song, Hanbaek Yi, Songyi Park, Go-un Woo, Dae-Won Lee, Tae-Yong Kim, Kyung-Hun Lee, Seock-Ah Im

“…Conclusion Our study showed genetic heterogeneity of breast cancer patients with gBRCA1 and gBRCA2 mutations in the Korean populations. Further studies on precision medicine are needed for tailored treatments of patients with genetic diversity among different ethnic groups.…”
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Comparison of birth weight, length, and head circumference between the BRISA-RP and Intergrowth‐21st cohorts by João Roberto R. Pimenta, Carlos Grandi, Davi C. Aragon, Viviane Cunha Cardoso

“…Results: The weight difference between Ribeirão Preto and Intergrowth-21st was small, being more pronounced in preterm infants (mean difference between the two populations of +266 g); for full‐term newborns, there was a mean difference of +66 g, and for post‐term infants, of −113 g. …”
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Application of vagus nerve stimulation on the rehabilitation of upper limb dysfunction after stroke: a systematic review and meta-analysis by Xu Wang, Qixin Ding, Tianshu Li, Wanyue Li, Jialin Yin, Yakun Li, Yuefang Li, Weisheng Zhuang

“…In the future, further high-quality studies with larger study populations, more comprehensive indicators, and thorough data are required to advance the clinical application of VNS.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier: CRD42023399820.…”
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چوب صنوبر سوپرپارامغناطیس فورفوریله: ویژگی‌های ریخت‌شناسی، فیزیکی و مکانیکی by مهدی مشکور, داوود رسولی, حسین یوسفی, افسانه رجبی

“…مواد و روش‌ها:سنتز درجای نانوذرات مگنتیت درون چوب صنوبر (Populous deltoides)، با استفاده محلول کلریدهای آهن II و III، با نسبت مولی 2:1، درون یک سیلندر خلاء/فشار انجام شد. …”
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Surveillance of noninvasive group A Streptococcus infections in French ambulatory pediatrics before and during the COVID-19 pandemic: a prospective multicenter study from 2018-2022 by Jérémie F. Cohen, Alexis Rybak, Andreas Werner, Fabienne Kochert, Fabienne Cahn-Sellem, Nathalie Gelbert, François Vié Le Sage, Christophe Batard, Stéphane Béchet, Hippolyte Corbaux, Bruno Frandji, Corinne Levy, Robert Cohen

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Proton therapy (PT) combined with concurrent chemotherapy for locally advanced non-small cell lung cancer with negative driver genes by Yonglong Jin, Shosei Shimizu, Yinuo Li, Yuan Yao, Xiguang Liu, Hongzong Si, Hideyuki Sakurai, Wenjing Xiao

“…This suggests a more suitable treatment modality and clinical evidence for populations with frail health, compromised cardio-pulmonary function, post-COVID-19 sequelae, and underlying comorbidities.…”
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The Effect of a Single High Dose of Vitamin D on Serum Levels of Its Metabolites in the Elderly by Dorota Leszczyńska, Alicja Szatko, Konrad Kowalski, Dorota Raczkiewicz, Magdalena Ostrowska, Waldemar Misiorowski, Wojciech Zgliczyński, Piotr Glinicki

“…However, the usage of liquid chromatography with tandem mass spectrometry (LC-MS/MS) technique allows to reliably assess a panel of vitamin D metabolites in serum or plasma, which may help to investigate the metabolic paths of vitamin D, especially in populations at risk of deficiency. Methods: A randomized, two-arms, open study was conducted on 58 patients (28 female and 30 male; aged from 61 to 96 years old). …”
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Imbalance of Lymphocyte Subsets and CD45RA-Expressing Cells in Intrathoracic Lymph Nodes, Alveolar Compartment and Bloodstream of Pulmonary Sarcoidosis Patients by Miriana d’Alessandro, Laura Bergantini, Sara Gangi, Paolo Cameli, Martina Armati, Matteo Fanetti, Fabrizio Mezzasalma, Stefano Baglioni, SARC-SI Study Group, Elena Bargagli

“…Comparative analysis found 18 cell populations that differed significantly between the three anatomical compartments. …”
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The trend of unintentional injury-related mortality among children aged under-five years in China, 2010–2020: a retrospective analysis from a national surveillance system by Xue Yu, Yanping Wang, Chunhua He, Leni Kang, Lei Miao, Yan Wu, Shirong Yang, Jun Zhu, Juan Liang, Qi Li, Li Dai, Xiaohong Li, Kui Deng, Jing Tao

“…Effective strategies should be strengthened to reduce unintentional injury in children and these policies and programmes should be targeted to more specific populations, such as rural areas and males.…”
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