Studies on collagen post-translational modifications by Langley, G

Post-translational modifications of BRAF and MITF by Ngeow, K

“…To this end, we have identified novel sites of post-translational modifications in two oncogenic proteins that are known to play pivotal roles in driving melanoma tumorigenesis. …”

Synthetic post-translational modification of histones by Nadal, S, Raj, R, Mohammed, S, Davis, B

“…A multitude of histone post-translational modifications (PTMs) have been discovered, providing a glance into the complex interplay of these epigenetic marks in cellular processes. …”

System level dynamics of post-translational modifications by White, Forest M., Gajadhar, Aaron

“…Significant biological insight can be gleaned by considering the contribution of dynamic protein post-translational modifications (PTMs) utilizing systems-level quantitative analysis. …”
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Physical consequences of natural and synthetic post-translational modifications by Kilgore, Henry R.(Henry Ralph)

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Post-translational modifications on the metal-sequestering protein calprotectin by Nolan, Elizabeth M., Peet, Janet J. Y.

“…Over the past decade, fundamental and clinical studies have revealed that the S100A8 and S100A9 subunits of CP exhibit a variety of post-translational modifications (PTMs). This review summarizes PTMs on the CP subunits that have been detected and highlights two recent studies that evaluated the structural and functional consequences of methionine and cysteine oxidation on CP. …”
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A literature survey of post-translational modification on lysine. by Tan, Li.

“…Lysine acetylation and methylation has emerged as major post-translational modifications (PTMs) for proteins in eukaryotic cells. …”
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Post-translational modification-regulated leukocyte adhesion and migration by Loh, Jia Tong, Su, I-hsin

“…This dynamic process of migration requires the coordination of large numbers of cytosolic and transmembrane proteins whose functional activities are typically regulated by post-translational modifications (PTMs). Our recent studies have shown that the lysine methyltransferase, Ezh2, critically regulates integrin signalling and governs the adhesion dynamics of leukocytes via direct methylation of talin, a key molecule that controls these processes by linking integrins to the actin cytoskeleton. …”
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Functional regulation of ppars through post-translational modifications by Brunmeir, Reinhard, Xu, Feng

“…In addition, PPAR functions are also regulated by various Post-translational modifications (PTMs). These PTMs include phosphorylation, SUMOylation, ubiquitination, acetylation, and O-GlcNAcylation, which are found at numerous modification sites. …”
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Chemical approaches to mapping the function of post-translational modifications. by Gamblin, D, van Kasteren, S, Chalker, J, Davis, B

“…Strategies for the chemical construction of synthetic proteins with precisely positioned post-translational modifications or their mimics offer a powerful method for dissecting the complexity of functional protein alteration and the associated complexity of proteomes.…”

Signalling to chromatin through post-translational modifications of HMGN. by Pogna, E, Clayton, A, Mahadevan, L

“…This chapter deals with the HMGN protein family, specifically their post-translational modification as part of regulatory networks. …”

Oxidative Post-translational Modifications Accelerate Proteolytic Degradation of Calprotectin by Stephan, Jules R., Yu, Fangting, Costello, Rebekah M., Bleier, Benjamin S., Nolan, Elizabeth Marie

“…Oxidative post-translational modifications affect the structure and function of many biomolecules. …”
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The cellular exportation of annexin 1 requires post-translational modification by Buckingham, J, Mulla, A, Tierney, T, Morris, J, Christian, H, Solito, E

Oxidative post-translational modifications and their involvement in the pathogenesis of autoimmune diseases. by Ryan, B, Nissim, A, Winyard, P

“…Increasing evidence demonstrates that such oxidative post-translational modifications result in the generation of neo-epitopes capable of eliciting both innate and adaptive immune responses. …”

Role of Pcf11 post-translational modifications in gene expression by Volanakis, A

Modls: Post-translational modification localization scoring with automatic specificity expansion by Trudgian, D, Singleton, R, Cockman, M, Ratcliffe, P, Kessler, B

“…ModLS, a new tool within our freely-available Central Proteomics Facilities Pipeline (CPFP), applies a localization scoring method to arbitrary post-translational modifications (PTMs). As well as localising PTMs based on amino-acid specificities are included in the initial search, ModLS can automatically consider additional specificities from UniMod. …”

Functional implications of IGF2-mediated post-translational modifications of REST by Mumtaz, M

“…The hypothesis tested in this thesis was whether IGF2 stimulation induces REST protein stabilisation by a post-translational modification preventing its ubiquitination and subsequent proteasomal degradation. …”

Tubulin post-translational modifications and the construction of microtubular organelles in Trypanosoma brucei. by Sasse, R, Gull, K

“…T. brucei therefore, represents a cell type with extremely active mechanisms for the post-translational modification of alpha-tubulin. Our analyses of the timing of acquisition and modulation in relation to MT construction in T. brucei, suggest that acetylation and detyrosination of alpha-tubulin are two independently regulated post-translational modifications, that are not uniquely associated with particular subsets of MTs of defined lability, position or function. …”

Hypoxia and hypoxia mimetics differentially modulate histone post-translational modifications by Hsu, K-F, Wilkins, S, Hopkinson, R, Sekirnik, R, Flashman, E, Kawamura, A, McCullagh, J, Walport, L, Schofield, C

“…Post-translational modifications (PTMs) to the tails of the core histone proteins are critically involved in epigenetic regulation. …”

Protein post-translational modification mimicry for cargo sorting to extracellular vesicles by Martin, C

“…</p> <p>The loading of cargo molecules into EVs constitutes one of the main challenges limiting clinical translation of EV-based therapies. Post-translational modification (PTM) of proteins with ubiquitin-like protein 3 (UBL3) has been previously implicated in the sorting of specific proteins into EVs. …”