Ex vivo mammalian prions are formed of paired double helical prion protein fibrils by Cassandra Terry, Adam Wenborn, Nathalie Gros, Jessica Sells, Susan Joiner, Laszlo L. P. Hosszu, M. Howard Tattum, Silvia Panico, Daniel K. Clare, John Collinge, Helen R. Saibil, Jonathan D. F. Wadsworth

Subjects: “…prion…”
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Manganese enhances prion protein survival in model soils and increases prion infectivity to cells. by Paul Davies, David R Brown

“…Prion diseases are considered to be transmissible. …”
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Ultraviolet-ozone treatment reduces levels of disease-associated prion protein and prion infectivity by McKenzie Debbie, Gilbert PUPA, Johnson Christopher J, Pedersen Joel A, Aiken Judd M

“…<p>Abstract</p> <p>Background</p> <p>Transmissible spongiform encephalopathies (TSEs) are a group of fatal neurodegenerative diseases caused by novel infectious agents referred to as prions. Prions appear to be composed primarily, if not exclusively, of a misfolded isoform of the cellular prion protein. …”
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Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion. by Romany Abskharon, Fei Wang, Alexandre Wohlkonig, Juxin Ruan, Sameh Soror, Gabriele Giachin, Els Pardon, Wenquan Zou, Giuseppe Legname, Jiyan Ma, Jan Steyaert

“…Prion or PrPSc is the proteinaceous infectious agent causing prion diseases in various mammalian species. …”
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Influence of Interspecies Transmission of Atypical Bovine Spongiform Encephalopathy Prions to Hamsters on Prion Characteristics by Kohtaro Miyazawa, Kentaro Masujin, Yuichi Matsuura, Yoshifumi Iwamaru, Hiroyuki Okada

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An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein. by Claudia Stincardini, Tania Massignan, Silvia Biggi, Saioa R Elezgarai, Valeria Sangiovanni, Ilaria Vanni, Michael Pancher, Valentina Adami, Jorge Moreno, Matteo Stravalaci, Giulia Maietta, Marco Gobbi, Alessandro Negro, Jesús R Requena, Joaquín Castilla, Romolo Nonno, Emiliano Biasini

“…Prion diseases are neurodegenerative conditions characterized by the conformational conversion of the cellular prion protein (PrPC), an endogenous membrane glycoprotein of uncertain function, into PrPSc, a pathological isoform that replicates by imposing its abnormal folding onto PrPC molecules. …”
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Loss of prion protein control of glucose metabolism promotes neurodegeneration in model of prion diseases. by Hélène Arnould, Vincent Baudouin, Anne Baudry, Luiz W Ribeiro, Hector Ardila-Osorio, Mathéa Pietri, Cédric Caradeuc, Cynthia Soultawi, Declan Williams, Marjorie Alvarez, Carole Crozet, Fatima Djouadi, Mireille Laforge, Gildas Bertho, Odile Kellermann, Jean-Marie Launay, Gerold Schmitt-Ulms, Benoit Schneider

“…Corruption of cellular prion protein (PrPC) function(s) at the plasma membrane of neurons is at the root of prion diseases, such as Creutzfeldt-Jakob disease and its variant in humans, and Bovine Spongiform Encephalopathies, better known as mad cow disease, in cattle. …”
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Plasmacytoid dendritic cells sequester high prion titres at early stages of prion infection. by Rocio Castro-Seoane, Holger Hummerich, Trevor Sweeting, M Howard Tattum, Jacqueline M Linehan, Mar Fernandez de Marco, Sebastian Brandner, John Collinge, Peter-Christian Klöhn

“…In most transmissible spongiform encephalopathies prions accumulate in the lymphoreticular system (LRS) long before they are detectable in the central nervous system. …”
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PRION-1 scales analysis supports use of functional outcome measures in prion disease. by Mead, S, Ranopa, M, Gopalakrishnan, G, Thompson, A, Rudge, P, Wroe, S, Kennedy, A, Hudson, F, MacKay, A, Darbyshire, J, Collinge, J, Walker, A

“…PRION-1, the largest clinical trial in prion disease to date, showed no effect of the potential therapeutic quinacrine on survival. …”

Prions : the new biology of proteins / by Soto, Claudio

Subjects: “…Prions…”

Prion biology : research and advances / by Břingue, Vincent

Subjects: “…Prion diseases…”

Protease-sensitive synthetic prions. by David W Colby, Rachel Wain, Ilia V Baskakov, Giuseppe Legname, Christina G Palmer, Hoang-Oanh B Nguyen, Azucena Lemus, Fred E Cohen, Stephen J DeArmond, Stanley B Prusiner

“…Prions arise when the cellular prion protein (PrP(C)) undergoes a self-propagating conformational change; the resulting infectious conformer is designated PrP(Sc). …”
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S. pombe placed on the prion map by Jacqueline Hayles

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Mechanisms for Curing Yeast Prions by Lois E. Greene, Farrin Saba, Rebecca E. Silberman, Xiaohong Zhao

Subjects: “…prion…”
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Neurometals in the Pathogenesis of Prion Diseases by Masahiro Kawahara, Midori Kato-Negishi, Ken-ichiro Tanaka

“…Prion diseases are progressive and transmissive neurodegenerative diseases. …”
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Teoría Prión - Enfermedades Priónicas by Gabriel Toro González, Uriel Esteban Sierra Zuleta, Luis Alberto Gómez Grosso

“…El objetivo de esta actualización es presentar un breve Resumen de la historia de la Teoría Prión, de la participación nacional en relación con la salud humana y animal, así como algunos avances sobre la estructura molecular del amiloide priónico. …”
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Epigenetic dominance of prion conformers. by Eri Saijo, Hae-Eun Kang, Jifeng Bian, Kristi G Bowling, Shawn Browning, Sehun Kim, Nora Hunter, Glenn C Telling

“…In contrast, Tg mice expressing OvPrP with valine (V) at 136 (OvPrP-V136) infected with the same prions developed disease rapidly, and the converted prion was comprised of an unstable (U), diffusely distributed conformer. …”
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Therapeutic implications of prion diseases by Cao Chen, Xiaoping Dong

Subjects: “…Prion disease…”
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Lions and prions and deer demise. by Michael W Miller, Heather M Swanson, Lisa L Wolfe, Fred G Quartarone, Sherri L Huwer, Charles H Southwick, Paul M Lukacs

“…BACKGROUND: Contagious prion diseases--scrapie of sheep and chronic wasting disease of several species in the deer family--give rise to epidemics that seem capable of compromising host population viability. …”
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An overview of animal prion diseases by Imran Muhammad, Mahmood Saqib

Subjects: “…Prion diseases…”
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