Neurotropic influenza A virus infection causes prion protein misfolding into infectious prions in neuroblastoma cells by Hideyuki Hara, Junji Chida, Keiji Uchiyama, Agriani Dini Pasiana, Etsuhisa Takahashi, Hiroshi Kido, Suehiro Sakaguchi

“…Abstract Misfolding of the cellular prion protein, PrPC, into the amyloidogenic isoform, PrPSc, which forms infectious protein aggregates, the so-called prions, is a key pathogenic event in prion diseases. …”
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Atypical Scrapie Prions from Sheep and Lack of Disease in Transgenic Mice Overexpressing Human Prion Protein by Jonathan D.F. Wadsworth, Susan Joiner, Jacqueline M. Linehan, Anne Balkema-Buschmann, John Spiropoulos, Marion M. Simmons, Peter C. Griffiths, Martin H. Groschup, James Hope, Sebastian Brandner, Emmanuel A. Asante, John Collinge

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Prion protein expression and processing in human mononuclear cells: the impact of the codon 129 prion gene polymorphism. by Christiane Segarra, Sylvain Lehmann, Joliette Coste

“…In both vCJD and experimental BSE models prion agents do reach the bloodstream, raising concerns regarding disease transmission through blood transfusion. …”
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Disease Transmission by Misfolded Prion-Protein Isoforms, Prion-Like Amyloids, Functional Amyloids and the Central Dogma by Martin L. Daus

Subjects: “…prion…”
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Quaternary structure of pathological prion protein as a determining factor of strain-specific prion replication dynamics. by Florent Laferrière, Philippe Tixador, Mohammed Moudjou, Jérôme Chapuis, Pierre Sibille, Laetitia Herzog, Fabienne Reine, Emilie Jaumain, Hubert Laude, Human Rezaei, Vincent Béringue

“…Prions are proteinaceous infectious agents responsible for fatal neurodegenerative diseases in animals and humans. …”
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Strain-Dependent Prion Infection in Mice Expressing Prion Protein with Deletion of Central Residues 91–106 by Keiji Uchiyama, Hironori Miyata, Yoshitaka Yamaguchi, Morikazu Imamura, Mariya Okazaki, Agriani Dini Pasiana, Junji Chida, Hideyuki Hara, Ryuichiro Atarashi, Hitomi Watanabe, Gen Kondoh, Suehiro Sakaguchi

Subjects: “…prions…”
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Prion protein amino acid determinants of differential susceptibility and molecular feature of prion strains in mice and voles. by Umberto Agrimi, Romolo Nonno, Giacomo Dell'Omo, Michele Angelo Di Bari, Michela Conte, Barbara Chiappini, Elena Esposito, Giovanni Di Guardo, Otto Windl, Gabriele Vaccari, Hans-Peter Lipp

“…The bank vole is a rodent susceptible to different prion strains from humans and various animal species. …”
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Double-Edge Sword of Sustained ROCK Activation in Prion Diseases through Neuritogenesis Defects and Prion Accumulation. by Aurélie Alleaume-Butaux, Simon Nicot, Mathéa Pietri, Anne Baudry, Caroline Dakowski, Philippe Tixador, Hector Ardila-Osorio, Anne-Marie Haeberlé, Yannick Bailly, Jean-Michel Peyrin, Jean-Michel Peyrin, Jean-Marie Launay, Odile Kellermann, Benoit Schneider

“…In prion diseases, synapse dysfunction, axon retraction and loss of neuronal polarity precede neuronal death. …”
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Prion protein modulates cellular iron uptake: a novel function with implications for prion disease pathogenesis. by Ajay Singh, Maradumane L Mohan, Alfred Orina Isaac, Xiu Luo, Jiri Petrak, Daniel Vyoral, Neena Singh

“…Converging evidence leaves little doubt that a change in the conformation of prion protein (PrP(C)) from a mainly alpha-helical to a beta-sheet rich PrP-scrapie (PrP(Sc)) form is the main event responsible for prion disease associated neurotoxicity. …”
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Safety and efficacy of quinacrine in human prion disease (PRION-1 study): a patient-preference trial. by Collinge, J, Gorham, M, Hudson, F, Kennedy, A, Keogh, G, Pal, S, Rossor, M, Rudge, P, Siddique, D, Spyer, M, Thomas, D, Walker, S, Webb, T, Wroe, S, Darbyshire, J

“…BACKGROUND: The propagation of prions, the causative agents of Creutzfeldt-Jakob disease and other human prion diseases, requires post-translational conversion of normal cellular prion protein to disease-associated forms. …”

ANALYSIS OF EIGHT RATING SCALES SUPPORTS THE USE OF FUNCTIONAL OUTCOME MEASURES IN PRION DISEASE CLINICAL TRIALS: EXPERIENCE FROM THE PRION-1 TRIAL AND THE NATIONAL PRION MONITORING COHORT by Thompson, A, Rudge, P, Wroe, S, Mead, S, Darbyshire, J, MacKay, A, Ranopa, M, Collinge, J, Gopalakrishnan, G, Walker, S

Analysis of Eight Rating Scales Supports the use of Functional Outcome Measures in Prion Disease Clinical Trials: Experience from the PRION-1 trial and the National Prion Monitoring Cohort by Mead, S, Thompson, A, Gopalakrishnan, G, Ranopa, M, Rudge, P, Wroe, S, Hudson, F, MacKay, A, Darbyshire, J, Collinge, J, Walker, S

Prion gene haplotypes of U.S. cattle by Harhay Gregory P, Smith Timothy PL, Keele John W, Heaton Michael P, Clawson Michael L, Laegreid William W

“…<p>Abstract</p> <p>Background</p> <p>Bovine spongiform encephalopathy (BSE) is a fatal neurological disorder characterized by abnormal deposits of a protease-resistant isoform of the prion protein. Characterizing linkage disequilibrium (LD) and haplotype networks within the bovine prion gene (<it>PRNP</it>) is important for 1) testing rare or common <it>PRNP </it>variation for an association with BSE and 2) interpreting any association of <it>PRNP </it>alleles with BSE susceptibility. …”
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Risk Analysis of Prion Diseases in Animals by Brian W.J. Mahy

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Prion protein gene in Alzheimer's disease by Paulo Caramelli

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Structural Bases of Prion Variation in Yeast by Vitaly V. Kushnirov, Alexander A. Dergalev, Maya K. Alieva, Alexander I. Alexandrov

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The Cellular Prion Protein and the Hallmarks of Cancer by Sophie Mouillet-Richard, Alexandre Ghazi, Pierre Laurent-Puig

Subjects: “…cellular prion protein…”
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Relationship between magnetism and prion protein by F. Balzano, M. Zedda, M. Basagni, S. Dei Giudici, A. Danani, V. Sanna

Subjects: “…prion protein, magnetism, IR spectra…”
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Αnti-prion effects of anthocyanins by Nikoletta Christoudia, Nikolaos Bekas, Eirini Kanata, Athanasia Chatziefsthathiou, Spyros Pettas, Korina Karagianni, Susana Margarida Da Silva Correia, Matthias Schmitz, Inga Zerr, Ioannis Tsamesidis, Konstantinos Xanthopoulos, Dimitra Dafou, Theodoros Sklaviadis

Subjects: “…Prion…”
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Molecular Barriers to Zoonotic Transmission of Prions by Marcelo A. Barria, Aru Balachandran, Masanori Morita, Tetsuyuki Kitamoto, Rona Barron, Jean Manson, Richard Knight, James W. Ironside, Mark W. Head

Subjects: “…prion disease…”
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