Individualized quality of life benefit and cost-effectiveness estimates of proton therapy for patients with oropharyngeal cancer by N. Patrik Brodin, Rafi Kabarriti, Clyde B. Schechter, Mark Pankuch, Vinai Gondi, Shalom Kalnicki, Madhur K. Garg, Wolfgang A. Tomé

Subjects: “…Proton therapy…”
Get full text

Dosimetric Uncertainties in Dominant Intraprostatic Lesion Simultaneous Boost Using Intensity Modulated Proton Therapy by Jun Zhou, PhD, Xiaofeng Yang, PhD, Chih-Wei Chang, PhD, Sibo Tian, MD, Tonghe Wang, PhD, Liyong Lin, PhD, Yinan Wang, MS, James Robert Janopaul-Naylor, MD, Pretesh Patel, MD, John D. Demoor, MS, Duncan Bohannon, MS, Alex Stanforth, MS, Bree Eaton, MD, Mark W. McDonald, MD, Tian Liu, PhD, Sagar Anil Patel, MD

“…Purpose: While intensity modulated proton therapy can deliver simultaneous integrated boost (SIB) to the dominant intraprostatic lesion (DIL) with high precision, it is sensitive to anatomic changes. …”
Get full text

An MRI sequence independent convolutional neural network for synthetic head CT generation in proton therapy by Lukas Zimmermann, Barbara Knäusl, Markus Stock, Carola Lütgendorf-Caucig, Dietmar Georg, Peter Kuess

Subjects: Get full text

Racial and Ethnic Demographic Reporting in Phase 2 Proton Therapy Clinical Trials: A Review by Jonathan S. Fakhry, M. Juliana Pena, Ariel Pomputius, Fantine Giap, MD, Raymond B. Mailhot Vega, MD

Subjects: “…proton therapy…”
Get full text

Dosimetric impact of geometric distortions in an MRI-only proton therapy workflow for lung, liver and pancreas by Hatice Selcen Dumlu, Giorgia Meschini, Christopher Kurz, Florian Kamp, Guido Baroni, Claus Belka, Chiara Paganelli, Marco Riboldi

Subjects: Get full text

Proton Therapy With Concurrent Chemotherapy for Thoracic Esophageal Cancer: Toxicity, Disease Control, and Survival Outcomes by Michael S. Rutenberg, MD, PhD, Bradford S. Hoppe, MD, MPH, Jason S. Starr, DO, Ziad Awad, MD, Mathew Thomas, MBBS, MD, Christopher G. Morris, MS, Perry Johnson, PhD, Randal H. Henderson, MD, MBA, Jeremy C. Jones, MD, Bharatsinh Gharia, MBBS, MD, Steven Bowers, MD, Herbert C. Wolfsen, MD, Sunil Krishnan, MBBS, MD, Stephen J. Ko, MD, Hani M. Babiker, MD, Romaine C. Nichols, Jr, MD

“…Patients received proton therapy to a median dose of 50.4-GyRBE (range, 50.4–64.8) in 1.8-Gy fractions.Acute and late toxicities were graded per the Common Terminology Criteria for Adverse Events, version 4.0 (US National Cancer Institute, Bethesda, Maryland). …”
Get full text

Advantages of intensity modulated proton therapy during hippocampal avoidance whole brain radiation therapy by Joshua Stoker, Sujay Vora, Ameet Patel, David Grosshans, Paul D. Brown, Tamara Vern-Gross, Martin Bues, Thomas Daniels, Bryce Allred, Arielle Uejo, Heidi Kosiorek, Marlene Bruso, Sameer Keole

“…Background and purpose: Intensity modulated proton therapy (IMPT) allows for modulation parameterized for individual beamlets by position, intensity, and depth. …”
Get full text

Normofractionated and moderately hypofractionated proton therapy: comparison of acute toxicity and early quality of life outcomes by Maciej J. Pelak, Birgit Flechl, Eugen Hug, Razvan Galalae, Razvan Galalae, Lisa Konrath, Joanna Góra, Piero Fossati, Carola Lütgendorf-Caucig, Slavisa Tubin, Rastko Konstantinovic, Ulrike Mock, Christoph Fussl, Petra Georg

Subjects: “…proton therapy…”
Get full text

Lower-Neck Sparing Using Proton Therapy in Patients with Uninvolved Neck Nasopharyngeal Carcinoma: Is It Safe? by Francesca De Felice, Alessandro Vai, Anna Maria Camarda, Nicola Alessandro Iacovelli, Ester Orlandi

“…With this Commentary, we aim to explore the feasibility of Intensity Modulated Proton Therapy (IMPT) in upper-neck irradiation of NPC N1-stage disease. …”
Get full text

Outcomes for pediatric patients with central nervous system germ cell tumors treated with proton therapy by Brad J. Greenfield, Sergio Jaramillo, Mirna Abboud, Anita Mahajan, Arnold C. Paulino, Susan McGovern, Mary F. McAleer, Murali Chintagumpala, M. Fatih Okcu, Soumen Khatua, Jack Su, David R. Grosshans

Subjects: “…Proton therapy…”
Get full text

Sharp dose profiles for high precision proton therapy using strongly focused proton beams by Fardous Reaz, Kyrre Ness Sjobak, Eirik Malinen, Nina Frederike Jeppesen Edin, Erik Adli

Get full text

Biological and Mechanical Synergies to Deal With Proton Therapy Pitfalls: Minibeams, FLASH, Arcs, and Gantryless Rooms by Alejandro Mazal, Juan Antonio Vera Sanchez, Daniel Sanchez-Parcerisa, Daniel Sanchez-Parcerisa, Daniel Sanchez-Parcerisa, Jose Manuel Udias, Jose Manuel Udias, Samuel España, Samuel España, Victor Sanchez-Tembleque, Victor Sanchez-Tembleque, Luis Mario Fraile, Luis Mario Fraile, Paloma Bragado, Paloma Bragado, Alvaro Gutierrez-Uzquiza, Alvaro Gutierrez-Uzquiza, Nuria Gordillo, Nuria Gordillo, Gaston Garcia, Juan Castro Novais, Juan Maria Perez Moreno, Lina Mayorga Ortiz, Amaia Ilundain Idoate, Marta Cremades Sendino, Carme Ares, Raymond Miralbell, Niek Schreuder

Subjects: “…proton therapy…”
Get full text

Clinical Implementation of Proton Therapy Using Pencil-Beam Scanning Delivery Combined With Static Apertures by Christian Bäumer, Christian Bäumer, Christian Bäumer, Christian Bäumer, Sandija Plaude, Sandija Plaude, Dalia Ahmad Khalil, Dalia Ahmad Khalil, Dalia Ahmad Khalil, Dirk Geismar, Dirk Geismar, Dirk Geismar, Dirk Geismar, Paul-Heinz Kramer, Paul-Heinz Kramer, Kevin Kröninger, Christian Nitsch, Jörg Wulff, Jörg Wulff, Beate Timmermann, Beate Timmermann, Beate Timmermann, Beate Timmermann

Subjects: “…proton therapy…”
Get full text

Combination of Proton Therapy and Radionuclide Therapy in Mice: Preclinical Pilot Study at the Paul Scherrer Institute by Cristina Müller, Maria De Prado Leal, Marco D. Dominietto, Christoph A. Umbricht, Sairos Safai, Rosalind L. Perrin, Martina Egloff, Peter Bernhardt, Nicholas P. van der Meulen, Damien C. Weber, Roger Schibli, Antony J. Lomax

Subjects: “…proton therapy…”
Get full text

In-vivo range verification analysis with in-beam PET data for patients treated with proton therapy at CNAO by Martina Moglioni, Martina Moglioni, Aafke Christine Kraan, Guido Baroni, Guido Baroni, Giuseppe Battistoni, Nicola Belcari, Nicola Belcari, Andrea Berti, Andrea Berti, Andrea Berti, Pietro Carra, Pietro Carra, Piergiorgio Cerello, Mario Ciocca, Angelica De Gregorio, Angelica De Gregorio, Micol De Simoni, Micol De Simoni, Damiano Del Sarto, Damiano Del Sarto, Marco Donetti, Yunsheng Dong, Yunsheng Dong, Alessia Embriaco, Maria Evelina Fantacci, Maria Evelina Fantacci, Veronica Ferrero, Elisa Fiorina, Elisa Fiorina, Marta Fischetti, Marta Fischetti, Gaia Franciosini, Gaia Franciosini, Giuseppe Giraudo, Francesco Laruina, Francesco Laruina, Davide Maestri, Marco Magi, Giuseppe Magro, Etesam Malekzadeh, Etesam Malekzadeh, Michela Marafini, Michela Marafini, Ilaria Mattei, Enrico Mazzoni, Paolo Mereu, Alfredo Mirandola, Matteo Morrocchi, Matteo Morrocchi, Silvia Muraro, Ester Orlandi, Vincenzo Patera, Vincenzo Patera, Francesco Pennazio, Marco Pullia, Alessandra Retico, Angelo Rivetti, Manuel Dionisio Da Rocha Rolo, Valeria Rosso, Valeria Rosso, Alessio Sarti, Alessio Sarti, Angelo Schiavi, Angelo Schiavi, Adalberto Sciubba, Adalberto Sciubba, Giancarlo Sportelli, Giancarlo Sportelli, Sara Tampellini, Marco Toppi, Marco Toppi, Giacomo Traini, Giacomo Traini, Antonio Trigilio, Antonio Trigilio, Serena Marta Valle, Francesca Valvo, Barbara Vischioni, Viviana Vitolo, Richard Wheadon, Maria Giuseppina Bisogni, Maria Giuseppina Bisogni

Subjects: “…proton therapy…”
Get full text

Conception of a New Recoil Proton Telescope for Real-Time Neutron Spectrometry in Proton-Therapy by Combe Rodolphe, Arbor Nicolas, el Bitar Ziad, Higueret Stéphane, Husson Daniel

“…Neutrons are the main type of secondary particles emitted in proton-therapy. Because of the risk of secondary cancer and other late occurring effects, the neutron dose should be included in the out-of-field dose calculations. …”
Get full text

CBCT-Based Dose Monitoring and Adaptive Planning Triggers in Head and Neck PBS Proton Therapy by Keaton Reiners, Roi Dagan, Adam Holtzman, Curtis Bryant, Sebastian Andersson, Rasmus Nilsson, Liu Hong, Perry Johnson, Yawei Zhang

“…Purpose: To investigate the feasibility of using cone-beam computed tomography (CBCT)-derived synthetic CTs to monitor the daily dose and trigger a plan review for adaptive proton therapy (APT) in head and neck cancer (HNC) patients. …”
Get full text

Clinical evaluation of synthetic computed tomography methods in adaptive proton therapy of lung cancer patients by Vicki Trier Taasti, Djoya Hattu, Stephanie Peeters, Anke van der Salm, Judith van Loon, Dirk de Ruysscher, Rasmus Nilsson, Sebastian Andersson, Erik Engwall, Mirko Unipan, Richard Canters

Subjects: Get full text

PITChing (professional organisations, innovative trial designs and collaborative approach) for evidence generation for proton therapy by Srinivas Chilukuri, Pankaj Kumar Panda, Rakesh Jalali

Get full text

Fast MCsquare-Based Independent Dose Verification Platform for Pencil Beam Scanning Proton Therapy by Chunbo Liu, Meng Wei Ho, Jiyeon Park, Wen Chien Hsi, Xiaoying Liang, Zuofeng Li, Yuntao Song, Hansheng Feng, Yawei Zhang

“…Purpose: To commission MCsquare (a multi-cores CPU-based dose calculation engine) for pencil beam scanning (PBS) proton therapy, integrate it into RayStation treatment plan system (TPS) to create a dedicated platform for fast independent dose verification. …”
Get full text