DPM as a radiation transport engine for PRIMO by Miguel Rodriguez, Josep Sempau, Christian Bäumer, Beate Timmermann, Lorenzo Brualla

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Maximum resection and immunotherapy improve glioblastoma patient survival: a retrospective single-institution prognostic analysis by Eiichi Ishikawa, Narushi Sugii, Masahide Matsuda, Hidehiro Kohzuki, Takao Tsurubuchi, Hiroyoshi Akutsu, Shingo Takano, Masashi Mizumoto, Hideyuki Sakurai, Akira Matsumura

“…In conclusion, GTR, proton therapy, and immunotherapy were good prognostic factors in single-center GBM cases. …”
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Proton Reirradiation for Locoregionally Recurrent Breast Cancer by Michael J. LaRiviere, MD, Alexandra Dreyfuss, MD, Neil K. Taunk, MD, MS, Gary M. Freedman, MD

“…Purpose: Local-regional recurrence (LRR) of breast cancer after prior adjuvant radiation (RT) can present a clinical challenge. Proton therapy is recommended by the American Society for Radiation Oncology in cases where reirrradiation is needed; however, data are limited. …”
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Does Risk-Adapted Proton Beam Therapy Have a Role as a Complementary or Alternative Therapeutic Option for Hepatocellular Carcinoma? by Tae Hyun Kim, Joong-Won Park, Bo Hyun Kim, Hyunjung Kim, Sung Ho Moon, Sang Soo Kim, Sang Myung Woo, Young-Hwan Koh, Woo Jin Lee, Dae Yong Kim, Chang-Min Kim

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Patient reported outcomes following proton pencil beam scanning vs. passive scatter/uniform scanning for localized prostate cancer: Secondary analysis of PCG 001-09 by Mark V. Mishra, Rahul Khairnar, Søren M. Bentzen, Gary Larson, Henry Tsai, Christopher Sinesi, Carlos Vargas, George Laramore, Carl Rossi, Lane Rosen, Kai Sun, William Hartsell

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Depression and anxiety in patients with uveal melanoma undergoing curative proton treatment—A prospective study by Christopher Rabsahl, Dirk Boehmer, Alexander Boeker, Ulrich Gauger, Ute Goerling, Johannes Gollrad

“…Methods We assessed patient‐reported outcomes regarding anxiety (GAD‐7) before and 2 years after proton therapy and depression (PHQ‐9) before, 1, and 2 years after proton therapy. …”
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Proton radiotherapy dose perturbations caused by esophageal stents of varying material composition are negligible in an experimental model by Sujai Jalaj, Sang Yeob Lee, Camille McGaw, Bijo K John, Zuofeng Li, Ziad T Awad, James S Scolapio, Juan C Munoz

“…Negligible dose perturbation is in keeping with the inherent advantage of proton therapy over traditional radiotherapy composed of photons – given its relative large mass, protons have little side scatter.…”
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Proton pencil minibeam irradiation of an in-vivo mouse ear model spares healthy tissue dependent on beam size. by Matthias Sammer, Esther Zahnbrecher, Sophie Dobiasch, Stefanie Girst, Christoph Greubel, Katarina Ilicic, Judith Reindl, Benjamin Schwarz, Christian Siebenwirth, Dietrich W M Walsh, Stephanie E Combs, Günther Dollinger, Thomas E Schmid

“…Proton radiotherapy using minibeams of sub-millimeter dimensions reduces side effects in comparison to conventional proton therapy due to spatial fractionation. Since the proton minibeams widen with depth, the homogeneous irradiation of a tumor can be ensured by adjusting the beam distances to tumor size and depth to maintain tumor control as in conventional proton therapy. …”
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Case Report: Treatment Planning Study to Demonstrate Feasibility of Transthoracic Ultrasound Guidance to Facilitate Ventricular Tachycardia Ablation With Protons by Rosalind Perrin, Patrick Maguire, Adriano Garonna, Georg Weidlich, Shelley Bulling, Marie Fargier-Voiron, Cedric De Marco, Eleonora Rossi, Mario Ciocca, Viviana Vitolo, Alfredo Mirandola

“…Recently, a non-invasive treatment option based on external photon or proton beam irradiation has been used to ablate the arrhythmogenic structures. Especially in proton therapy, based on its steep dose gradient, it is crucial to monitor the motion of the heart in order to ensure that the radiation dose is delivered to the correct location. …”
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Clinical Effectiveness of Hypofractionated Proton Beam Therapy for Liver Metastasis From Breast Cancer by Tae Hyun Kim, Keun Seok Lee, Sung Hoon Sim, Yeon-Joo Kim, Dae Yong Kim, Heejung Chae, Eun-Gyeong Lee, Jai Hong Han, So Youn Jung, Seeyoun Lee, Han Sung Kang, Eun Sook Lee

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Renal cell carcinoma metastasis to the ciliary body responds to proton beam radiotherapy: a case report by Loredo Lilia, Khazai Bahram, Alasil Tarek, Rauser Michael E

“…The tumor size peaked at 6.11 × 6.06 mm before the start of proton therapy, which reduced the tumor size to 5.07 × 4.39 mm.…”
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Characterization of the proton pulsed beam at CMAM by Viñals S., Sánchez-Parcerisa D., Fraile L.M., España S., García G., García-Díaz M., SánchezTembleque V., Udías J.M.

“…The results point out that the pulses obtained are suitable for preclinical proton-therapy studies in the FLASH regime, which consists on fractionating the dose in time with short and intense pulses. …”
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MiR-630 Promotes Radioresistance by Induction of Anti-Apoptotic Effect via Nrf2–GPX2 Molecular Axis in Head–Neck Cancer by Guo-Rung You, Ann-Joy Cheng, Eric Yi-Liang Shen, Kang-Hsing Fan, Yi-Fang Huang, Yu-Chen Huang, Kai-Ping Chang, Joseph T. Chang

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Deep-learning-based deformable image registration of head CT and MRI scans by Alexander Ratke, Elena Darsht, Feline Heinzelmann, Feline Heinzelmann, Feline Heinzelmann, Feline Heinzelmann, Kevin Kröninger, Beate Timmermann, Beate Timmermann, Beate Timmermann, Beate Timmermann, Beate Timmermann, Christian Bäumer, Christian Bäumer, Christian Bäumer, Christian Bäumer, Christian Bäumer

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Normal Tissue Integral Dose as a Result of Prostate Radiation Therapy: A Quantitative Comparison Between High-Dose-Rate Brachytherapy and Modern External Beam Radiation Therapy Tec... by Vincent P. Grzywacz, MD, Jessica D. Arden, MD, PhD, Nikhil P. Mankuzhy, MD, Gary S. Gustafson, MD, Evelyn A. Sebastian, BS, Veronica L. Abbott, MS, Kailee J. Walters, MS, Julie A. Puzzonia, MS, Amy S. Limbacher, BS, Jason M. Hafron, MD, Daniel J. Krauss, MD

“…Conclusions: High-dose-rate brachytherapy is an effective technique for reducing dose to nontarget body tissues relative to volumetric modulated arc therapy, stereotactic body radiation therapy, and pencil-beam scanning proton therapy.…”
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RE-IRRADIATION OF NTRACRANIAL TUMORS WITH ACTIVE BEAM SCANNING PROTONS by I. A. Gulidov, K. B. Gordon, D. V. Gogolin, Yu. S. Mardynsky, O. G. Lepilina, D. V. Neledov, V. N. Galkin, A. D. Kaprin

“…We present 3 case reports of using active beam scanning proton therapy for re-irradiation of intracranial tumors. …”
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Longer Survival and Preserved Liver Function after Proton Beam Therapy for Patients with Unresectable Hepatocellular Carcinoma by Takuto Nosaka, Hidetaka Matsuda, Ryotaro Sugata, Yu Akazawa, Kazuto Takahashi, Tatsushi Naito, Masahiro Ohtani, Kazuyuki Kinoshita, Tetsuya Tsujikawa, Yoshitaka Sato, Yoshikazu Maeda, Hiroyasu Tamamura, Yasunari Nakamoto

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Development of a Real-Time Thermoplastic Mask Compression Force Monitoring System Using Capacitive Force Sensor by Tae-Ho Kim, Min-Seok Cho, Dong-Seok Shin, Dong Ho Shin, Siyong Kim

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An Update From the Pediatric Proton Consortium Registry by Clayton B. Hess, Daniel J. Indelicato, Arnold C. Paulino, William F. Hartsell, Christine E. Hill-Kayser, Stephanie M. Perkins, Anita Mahajan, Nadia N. Laack, Ralph P. Ermoian, Andrew L. Chang, Suzanne L. Wolden, Victor S. Mangona, Young Kwok, John C. Breneman, John P. Perentesis, Sara L. Gallotto, Elizabeth A. Weyman, Benjamin V. M. Bajaj, Miranda P. Lawell, Beow Y. Yeap, Torunn I. Yock

“…The median follow-up is 1.5 years with a range of 0.14 to 4.6 years.ConclusionA large prospective population of children irradiated with proton therapy has reached a critical milestone to facilitate long-awaited clinical outcomes research in the modern era. …”
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The Performance of LiF:Mg-Ti for Proton Dosimetry within the Framework of the MoVe IT Project by Vittoria D’Avino, Francesco Tommasino, Stefano Lorentini, Giuseppe La Verde, Mariagabriella Pugliese

“…Proton therapy represents a technologically advanced method for delivery of radiation treatments to tumors. …”
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