Monitoring of Interfractional Proton Range Verification and Dosimetric Impact Based on Daily CBCT for Pediatric Patients with Pelvic Tumors by Ozgur Ates, Jinsoo Uh, Fakhriddin Pirlepesov, Chia-Ho Hua, Thomas E. Merchant, Matthew J. Krasin

“…The dosimetric impact was due to proton range pullback or overshoot, which led to reduced coverage in CTV Dmin averaging 12.1% and 11.3% in the rescanned and synthetic CT verification plans, respectively; (4) Conclusions: The study demonstrated that synthetic CT generated by deforming the original planning CT to daily CBCT can be used to quantify proton range changes and predict adverse dosimetric scenarios without the need for excessive rescanned CT scans during large interfractional variations in adaptive proton therapy of pediatric pelvic tumors.…”
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Technical note: Defining cyclotron based clinical scanning proton machines in a FLUKA Monte Carlo system by Fiorini, F, Schreuder, N, Van den Heuvel, F

“…<strong>Methods</strong> The described beam is produced at the Provision Proton Therapy Center (Knoxville, Tennessee, USA) using a cyclotron-based IBA Proteus Plus equipment. …”

Patient positioning in the proton radiotherapy era by Dimiccoli Vincenzo, Benassi Marcello, D'Andrea Marco, Strigari Lidia, Devicienti Salvatore, Portaluri Maurizio

“…<p>Abstract</p> <p>The main hindrance to the diffusion of proton therapy facilities is the high cost for gantry installations. …”
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Stereotactic Radiosurgery in the Management of Patients With Brain Metastases of Non-Small Cell Lung Cancer: Indications, Decision Tools and Future Directions by Dianne Hartgerink, Britt van der Heijden, Dirk De Ruysscher, Dirk De Ruysscher, Alida Postma, Linda Ackermans, Ann Hoeben, Monique Anten, Philippe Lambin, Karin Terhaag, Arthur Jochems, Andre Dekker, Andre Dekker, Janna Schoenmaekers, Lizza Hendriks, Jaap Zindler, Jaap Zindler

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Glioblastoma multiforme - case presentation and literature review by Jakub Litak, Joanna Litak, Wojciech Czyżewski, Paulina Miziak

“…Presented case of 75y.o. patient diagnosed with GBM underwent full treatment : surgery and adjuvant proton-therapy. Despite new therapy development, overall survival time of GBM patients is still unacceptable.…”
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Commentary: The Impact of the Time Interval Between Radiation and Hyperthermia on Clinical Outcome in Patients With Locally Advanced Cervical Cancer by Michiel Kroesen, Michiel Kroesen, H. Tim Mulder, Gerard C. van Rhoon, Martine Franckena

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Novel Monthly Quality Assurance Regimen and 5-Year Analysis Using a Proton Metrology System by Ozgur Ates, PhD, Jackie Faught, PhD, Fakhriddin Pirlepesov, PhD, David Sobczak, Chia-ho Hua, PhD, Thomas E. Merchant, DO, PhD

“…Purpose: To develop a novel, monthly quality assurance (QA) regimen for a proton therapy system that uses 2 custom phantoms, each housing a commercial scintillator detector and a charge-coupled device camera. …”
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Design of Low Level RF Control System for 250 MeV Cyclotron by MU Xueer;YIN Zhiguo;WEI Junyi;LIU Ping;SONG Qiqi

“…A 250 MeV superconducting cyclotron for proton therapy has been developed by the China Institute of Atomic Energy (CIAE). …”
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Radiation dose and image quality of CT fluoroscopy with partial exposure mode by Keisuke Takiguchi, Atsushi Urikura, Tsukasa Yoshida, Yoshihiro Nakaya, Masahiro Endo, Takeshi Aramaki

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Risk factors for aspiration pneumonia during concurrent chemoradiotherapy or bio-radiotherapy for head and neck cancer by Hiromichi Shirasu, Tomoya Yokota, Satoshi Hamauchi, Yusuke Onozawa, Hirofumi Ogawa, Tsuyoshi Onoe, Tetsuro Onitsuka, Takashi Yurikusa, Keita Mori, Hirofumi Yasui

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Definitive Chemoradiotherapy versus Radical Hysterectomy Followed by Tailored Adjuvant Therapy in Women with Early-Stage Cervical Cancer Presenting with Pelvic Lymph Node Metastasi... by Jongmoo Park, Yeon-Joo Kim, Mi-Kyung Song, Joo-Hyun Nam, Sang-Yoon Park, Young-Seok Kim, Joo-Young Kim

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High LET-Like Radiation Tracks at the Distal Side of Accelerated Proton Bragg Peak by Dakota Horendeck, Kade D. Walsh, Hirokazu Hirakawa, Akira Fujimori, Hisashi Kitamura, Takamitsu A. Kato

“…Proton therapy is a type of hadron radiotherapy used for treating solid tumors. …”
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Safety and Feasibility of Magnetic Resonance Imaging Simulation for Radiation Treatment Planning in Pediatric Patients: A Single Institution Experience by Samantha M. Buszek, MD, Shane Ikner, BA, Laura Wiedemann, MS, Jihong Wang, PhD, Mary Fran McAleer, MD, PhD, David R. Grosshans, MD, PhD, Arnold de la Cruz Paulino, MD, Susan L. McGovern, MD, PhD, Caroline Chung, MD, MSc

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Estimation of the risk for radiation-induced liver disease following photon- or proton-beam radiosurgery of liver metastases by Gracinda Mondlane, Ana Ureba, Michael Gubanski, P A Lind, Albert Siegbahn

“…The clinical implementation of such a model-based approach to select liver metastases patients to proton therapy needs to be made with caution while considering the uncertainties involved in the NTCP estimations.…”
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Variations in Resources Among Radiation Oncology Residency Programs in the United States by Toms Vengaloor Thomas, MD, Teessa Perekattu Kuruvilla, MD, Jenna Kahn, MD, Eldrin Bhanat, MD, MPH, Amy Q. Parr, BS, Ashley Albert, MD, Mudit Chowdhary, MD, Sushil Beriwal, MD, Srinivasan Vijayakumar, MD

“…Only 19 programs (20%) had in-house proton therapy availability; however, 37 programs (39%) offered proton therapy training via resident rotation at an affiliated institution. …”
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Feasibility Study of a Proton Irradiation Facility for Radiobiological Measurements at an 18 MeV Cyclotron by Anna Baratto-Roldán, María del Carmen Jiménez-Ramos, Maria Cristina Battaglia, Javier García-López, María Isabel Gallardo, Miguel A. Cortés-Giraldo, José M. Espino

“…Measurements of this kind are of interest for proton therapy, since the variation of proton RBE at the distal edge of the Bragg curve may have implications in clinical proton therapy treatments. …”
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Proton vs photon: A model-based approach to patient selection for reduction of cardiac toxicity in locally advanced lung cancer by Teoh, S, Fiorini, F, George, B, Vallis, KA, Van Den Heuvel, F

“…<p><strong>Purpose/Objective:</strong> To use a model-based approach to identify a sub-group of patients with locally advanced lung cancer who would benefit from proton therapy compared to photon therapy for reduction of cardiac toxicity.…”

Investigating survival, quality of life and cognition in PROton versus photon therapy for IDH-mutated diffuse grade 2 and 3 GLIOmas (PRO-GLIO): a randomised controlled trial in Nor... by Inge C Olsen, Thomas Henry, Corina Silvia Rueegg, Asgeir S Jakola, Hanne Blakstad, Petter Brandal, Liv Cathrine Heggebø, Ida Maria Henriksen Borgen, Hillevi Rylander, Cecilie Kiserud, Tonje Haug Nordenmark, Taran Paulsen Hellebust, Morten Egeberg Evensen, Magnus Gustavsson, Christina Ramberg, Mette Sprauten, Henriette Magelssen, Janani Moorthy, Karin Andersson, Ingela Raunert, Cecilie Moe, Carin Granlund, Dorota Goplen, Jorunn Brekke, Tor-Christian Aase Johannessen, Tora Skeidsvoll Solheim, Kirsten Marienhagen, Øyvind Humberset, Per Bergström, Måns Agrup, Ludvig Dahl, Michael Gubanski, Helene Gojon, Carl-Johan Brahme, Isabelle Rydén, Einar O Vik-Mo, Hanne C. Lie, Lars Asphaug, Maziar Hervani, Ingrid Kristensen, Rolf J Ledal, Eskil Degsell, Katja Werlenius, Malin Blomstrand

“…Proton therapy enables sparing of non-neoplastic tissue from radiation. …”
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Editorial: Machine learning in radiation oncology by Wei Zhao, Wei Zhao, Ye Zhang, Jia Wu, Xiaomeng Li, Yuming Jiang

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Different Approaches in Radiation Therapy by Rolf-Dieter eKortmann

“…Modern treatment technologies including fractionated 3-d conformal radiotherapy, intensity modulated radiation therapy and recently proton therapy are able to precisely cover the target while preserving surrounding tissue,Tumour controls between 80 and in access of 90 % can be achieved. …”
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