A bibliometric analysis of cardiotoxicity in cancer radiotherapy by Mengting Che, Mengting Che, Yuanqiong Duan, Yuanqiong Duan, Rutie Yin, Rutie Yin

“…High-frequency keywords in the analysis include risk factors, cancer types, heart disease, survival, trials, proton therapy (PT), etc.ConclusionFuture research on RIHD will mostly focus on thoracic cancer, whose exact cause is yet unknown, with preclinical trials playing an important role. …”
Get full text

Machine Learning Model to Predict Pseudoprogression Versus Progression in Glioblastoma Using MRI: A Multi-Institutional Study (KROG 18-07) by Bum-Sup Jang, Andrew J. Park, Seung Hyuck Jeon, Il Han Kim, Do Hoon Lim, Shin-Hyung Park, Ju Hye Lee, Ji Hyun Chang, Kwan Ho Cho, Jin Hee Kim, Leonard Sunwoo, Seung Hong Choi, In Ah Kim

Get full text

A hybrid multi-particle approach to range assessment-based treatment verification in particle therapy by Ilker Meric, Enver Alagoz, Liv B. Hysing, Toni Kögler, Danny Lathouwers, William R. B. Lionheart, John Mattingly, Jasmina Obhodas, Guntram Pausch, Helge E. S. Pettersen, Hunter N. Ratliff, Marta Rovituso, Sonja M. Schellhammer, Lena M. Setterdahl, Kyrre Skjerdal, Edmond Sterpin, Davorin Sudac, Joseph A. Turko, Kristian S. Ytre-Hauge, The NOVO collaboration

“…A quasi-monolithic organic detector array is proposed, and its feasibility for detecting range shifts in the context of proton therapy is explored through Monte Carlo simulations of realistic patient models and detector resolution effects. …”
Get full text

A Portable Three-Layer Compton Camera for Wide-Energy-Range Gamma-ray Imaging: Design, Simulation and Preliminary Testing by Jipeng Zhang, Xiong Xiao, Ye Chen, Bin Zhang, Xinhua Ma, Xianyun Ai, Jinglun Li

“…Further improving the upper energy limit of gamma-ray imaging has important application significance in the active interrogation of special nuclear materials and chemical warfare agents, as well as range verification of proton therapy. (2) Methods: To realize gamma-ray imaging in a wide energy range of 0.3~7 MeV, a principle prototype, named a portable three-layer Compton camera, is developed using the scintillation detector that consists of an silicon photomultiplier array coupled with a Gd₃Al₂Ga₃O₁₂:Ce pixelated scintillator array. …”
Get full text

Geometric and dosimetric impact of 3D generative adversarial network-based metal artifact reduction algorithm on VMAT and IMPT for the head and neck region by Mitsuhiro Nakamura, Megumi Nakao, Keiho Imanishi, Hideaki Hirashima, Yusuke Tsuruta

“…Abstract Background We investigated the geometric and dosimetric impact of three-dimensional (3D) generative adversarial network (GAN)-based metal artifact reduction (MAR) algorithms on volumetric-modulated arc therapy (VMAT) and intensity-modulated proton therapy (IMPT) for the head and neck region, based on artifact-free computed tomography (CT) volumes with dental fillings. …”
Get full text

Short and long-term evaluation of the impact of proton minibeam radiation therapy on motor, emotional and cognitive functions by Charlotte Lamirault, Valérie Doyère, Marjorie Juchaux, Frederic Pouzoulet, Dalila Labiod, Remi Dendale, Annalisa Patriarca, Catherine Nauraye, Marine Le Dudal, Grégory Jouvion, David Hardy, Nicole El Massioui, Yolanda Prezado

“…Along this line, proton minibeam radiation therapy (pMBRT) is a novel strategy that allows the spatial modulation of the dose, leading to minimal damage to brain structures compared to a high dose (25 Gy in one fraction) of standard proton therapy (PT). The aim of the present study was to evaluate whether pMBRT also preserves important cerebral functions. …”
Get full text

Tumor Suppressor miRNA-503 Inhibits Cell Invasion in Head and Neck Cancer through the Wnt Signaling Pathway via the WNT3A/MMP Molecular Axis by Shang-Ju Tang, Kang-Hsing Fan, Guo-Rung You, Shiang-Fu Huang, Chung-Jan Kang, Yi-Fang Huang, Yu-Chen Huang, Joseph Tung-Chieh Chang, Ann-Joy Cheng

Get full text

Local MRI before and after Tumor Resection in Neuroblastoma: Impact of Residual Disease on Event Free Survival by Jürgen F. Schäfer, Sebastian Gassenmaier, Steven Warmann, Cristian Urla, Leonie Frauenfeld, Tim Flaadt, Maryanna Chaika, Michael Esser, Ilias Tsiflikas, Beate Timmermann, Jörg Fuchs

Get full text

Patient‐reported outcomes in childhood head and neck rhabdomyosarcoma survivors and their relation to physician‐graded adverse events—A multicenter study using the FACE‐Q Craniofac... by Michèle Morfouace, Marinka L. F. Hol, Reineke A. Schoot, Olga Slater, Daniel J. Indelicato, Frédéric Kolb, Ludwig E. Smeele, Johannes H. M. Merks, Charlene Rae, Heleen Maurice‐Stam, Anne F. Klassen, Martha A. Grootenhuis

Get full text

Global Radiotherapy: Current Status and Future Directions—White Paper by May Abdel-Wahab, Soehartati S. Gondhowiardjo, Arthur Accioly Rosa, Yolande Lievens, Noura El-Haj, Jose Alfredo Polo Rubio, Gregorius Ben Prajogi, Herdis Helgadottir, Eduardo Zubizarreta, Ahmed Meghzifene, Varisha Ashraf, Stephen Hahn, Tim Williams, Mary Gospodarowicz

Get full text

Treatment interruptions affect biochemical failure rates in prostate cancer patients treated with proton beam therapy: Report from the multi-institutional proton collaborative grou... by James E. Han, John Chang, Lane Rosen, William Hartsell, Henry Tsai, Jonathan Chen, Mark V. Mishra, Daniel Krauss, J. Isabelle Choi, Charles B. Simone, Shaakir Hasan

Get full text

PET/CT-based adaptive radiotherapy of locally advanced non-small cell lung cancer in multicenter yDEGRO ARO 2017-01 cohort study by Matthias Mäurer, Lukas Käsmann, Daniel F. Fleischmann, Michael Oertel, Danny Jazmati, Daniel Medenwald, Young DEGRO Trial Group

Get full text

Low CDK Activity and Enhanced Degradation by APC/C^CDH1 Abolishes CtIP Activity and Alt-EJ in Quiescent Cells by Fanghua Li, Emil Mladenov, Yanjie Sun, Aashish Soni, Martin Stuschke, Beate Timmermann, George Iliakis

Get full text

Management of Chordoma and Chondrosarcoma with Fractionated Stereotactic Radiotherapy by Harish N. Vasudevan, Harish N. Vasudevan, David R. Raleigh, Julian Johnson, Adam A. Garsa, Philip V. Theodosopoulos, Manish K. Aghi, Christopher Ames, Michael W. McDermott, Igor J. Barani, Steve E. Braunstein

“…One patient previously treated with proton therapy died from radiation vasculopathy 9 months after FSRT. …”
Get full text

An Analysis of Major Target Deviations in Craniospinal Irradiation Treatment Plans for Patients With Intermediate-Risk Medulloblastoma Within a Phase 3 Clinical Trial (Children's O... by Joshua P. Schiff, MD, Yimei Lee, MS, Yu Wang, MS, Stephanie M. Perkins, MD, Sandy K. Kessel, MD, Thomas J. Fitzgerald, MD, Nicole A. Larrier, MD, Jeff M. Michalski, MD, MBA

“…Conclusions: Although intensity modulated radiation therapy and proton therapy are promising in improving conformity and sparing organs at risk, technology does not substitute for careful anatomic definition of target volumes. …”
Get full text

High-energy quasi-monoenergetic proton beam from micro-tube targets driven by Laguerre–Gaussian lasers by S Jin, Y L Yao, B F Lei, G Y Chen, C T Zhou, S P Zhu, X T He, B Qiao

“…High-energy proton beams with low energy spread and angular divergence are highly valuable in various applications, such as proton therapy, ultrafast science, and nuclear physics. …”
Get full text

Therapy Resistance of Glioblastoma in Relation to the Subventricular Zone: What Is the Role of Radiotherapy? by Ekin Ermiş, Alexander Althaus, Marcela Blatti, Emre Uysal, Dominic Leiser, Shokoufe Norouzi, Elena Riggenbach, Hossein Hemmatazad, Uzeyir Ahmadli, Franca Wagner

Get full text

An uncertainty metric to evaluate deformation vector fields for dose accumulation in radiotherapy by Akihiro Takemura, Akira Nagano, Hironori Kojima, Tomohiro Ikeda, Noriomi Yokoyama, Kosuke Tsukamoto, Kimiya Noto, Naoki Isomura, Shinichi Ueda, Hiroki Kawashima

Get full text

Improve dosimetric outcome in stage III non-small-cell lung cancer treatment using spot-scanning proton arc (SPArc) therapy by Xiaoqiang Li, Peyman Kabolizadeh, Di Yan, An Qin, Jun Zhou, Ye Hong, Thomas Guerrero, Inga Grills, Craig Stevens, Xuanfeng Ding

“…Abstract Background To evaluate spot-scanning proton arc therapy (SPArc) and multi-field robust optimized intensity modulated proton therapy (RO-IMPT) in treating stage III non-small-cell lung cancer (NSCLC) patients. …”
Get full text

Impact of Systemic Autoimmune Diseases on Treatment Outcomes and Radiation Toxicities in Patients with Stage I Non-Small Cell Lung Cancer Receiving Stereotactic Body Radiation Ther... by Zhe Chen, Hotaka Nonaka, Hiroshi Onishi, Eiji Nakatani, Mitsuhiko Oguri, Masahide Saito, Shinichi Aoki, Kan Marino, Takafumi Komiyama, Kengo Kuriyama, Masayuki Araya, Licht Tominaga, Ryo Saito, Yoshiyasu Maehata, Ryoji Shinohara

Get full text