Chronic khat (Catha edulis) and alcohol marginally alter complete blood counts, clinical chemistry, and testosterone in male rats by Alele PE, Ajayi AM, Imanirampa L

“…Paul E Alele,1 Abayomi M Ajayi,2 Lawrence Imanirampa11Department of Pharmacology and Therapeutics, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda; 2Department of Pharmacology and Toxicology, Faculty of Biomedical Sciences, Kampala International University – Western Campus, Bushenyi, UgandaIntroduction: Khat (Catha edulis) is a recreational psychoactive drug with psychostimulant properties. While the use of this drug is widespread in eastern Africa, including the Horn of Africa, surveys and anecdotal data show that its use has become cosmopolitan, with users now living in Europe and North America as well. …”
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Evidence for the Effectiveness and Acceptability of e-SBI or e-SBIRT in the Management of Alcohol and Illicit Substance Use in Pregnant and Post-partum Women by Trecia A. Wouldes, Andi Crawford, Andi Crawford, Suzanne Stevens, Karolina Stasiak

“…Alcohol and illicit psychoactive drug use during pregnancy have increased worldwide, putting women and their children's health and development at risk. …”
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Opioid-related deaths during hospital admissions or shortly after discharge in the United Kingdom: A thematic framework analysis of coroner reports. by Dan Lewer, Thomas D Brothers, Magdalena Harris, Kirsten L Rock, Caroline S Copeland

“…<h4>Methods</h4>We used the National Programme on Substance Abuse Deaths, a database of coroner reports for deaths following psychoactive drug use in England, Wales, and Northern Ireland. …”
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Opioid-related deaths during hospital admissions or shortly after discharge in the United Kingdom: A thematic framework analysis of coroner reports by Dan Lewer, Thomas D. Brothers, Magdalena Harris, Kirsten L. Rock, Caroline S. Copeland

“…<h4>Methods</h4> We used the National Programme on Substance Abuse Deaths, a database of coroner reports for deaths following psychoactive drug use in England, Wales, and Northern Ireland. …”
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<i>N</i>-[1,3-Dialkyl(aryl)-2-oxoimidazolidin-4-ylidene]-aryl(alkyl)sulphonamides as Novel Selective Human Cannabinoid Type 2 Receptor (hCB2R) Ligands; Insights into the Mechanism... by Eleonora Gianquinto, Federica Sodano, Barbara Rolando, Magdalena Kostrzewa, Marco Allarà, Ali Mokhtar Mahmoud, Poulami Kumar, Francesca Spyrakis, Alessia Ligresti, Konstantin Chegaev

“…Starting with a scaffold selected from the NIH Psychoactive Drug Screening Program Repository, through a combination of molecular modeling and structure–activity relationship studies, we were able to identify the chemical features leading to finely tuned hCB2R selectivity. …”
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New Potentiometric Screen-Printed Platforms Modified with Reduced Graphene Oxide and Based on Man-Made Imprinted Receptors for Caffeine Assessment by Hisham S. M. Abd-Rabboh, Abdel El-Galil E. Amr, Abdulrahman A. Almehizia, Ahmed M. Naglah, Ayman H. Kamel

“…Caffeine is a psychoactive drug that is administered as a class II psychotropic substance. …”
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Interactions between antidepressants and antihypertensive and glucose lowering drugs among patients in the HIPERDIA Program, Coronel Fabriciano, Minas Gerais State, Brazil Interaçõ... by Paula Vieira Coelho, Carla de Arêdes Brum

“…Data were collected through the patient registry in the HIPERDIA Program and the local psychoactive drug dispensing system. Interactions were classified as due to pharmacokinetic and/or pharmacodynamic mechanisms. …”
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Anxiety-like behavior and whole-body cortisol responses to components of energy drinks in zebrafish (Danio rerio) by Alia O. Alia, Maureen L. Petrunich-Rutherford

“…Caffeine (1,3,7-trimethylpurine-2,6-dione), the world’s most commonly used psychoactive drug, acts as an adenosine receptor blocker and a mild central nervous system stimulant. …”
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Generating evidence on the use of Image and performance enhancing drugs in the UK: results from a scoping review and expert consultation by the Anabolic Steroid UK network by Jim McVeigh, Evelyn Hearne, Ian Boardley, Geoff Bates, Vivian Hope, Rob Ralphs, Marie Claire Van Hout

“…The studies illustrated the diverse populations of people who use a range of enhancement drugs including concomitant psychoactive drug use. A number of papers focused on blood borne viruses and associated issues, while others reported on the uptake of needle and syringe programmes. …”
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Novel Oleanolic Acid-Tryptamine and -Fluorotryptamine Amides: From Adaptogens to Agents Targeting In Vitro Cell Apoptosis by Uladzimir Bildziukevich, Marie Kvasnicová, David Šaman, Lucie Rárová, Zdeněk Wimmer

“…Background: Oleanolic acid is a natural plant adaptogen, and tryptamine is a natural psychoactive drug. To compare their effects of with the effect of their derivatives, tryptamine and fluorotryptamine amides of oleanolic acid were designed and synthesized. …”
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Caffeine Controls Glutamatergic Synaptic Transmission and Pyramidal Neuron Excitability in Human Neocortex by Amber Kerkhofs, Amber Kerkhofs, Ana C. Xavier, Beatriz S. da Silva, Paula M. Canas, Sander Idema, Johannes C. Baayen, Samira G. Ferreira, Rodrigo A. Cunha, Rodrigo A. Cunha, Huibert D. Mansvelder

“…Caffeine is the most widely used psychoactive drug, bolstering attention and normalizing mood and cognition, all functions involving cerebral cortical circuits. …”
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Impact of COVID-19 Pandemic on Men Who Have Sex With Men That Practice Chemsex in France: Results From the National ERAS Web Survey by Perrine Roux, Cécile Donadille, Gabriel Girard, Bruno Spire, Christel Protière, Annie Velter

“…Specifically, we first compared the subpopulation of MSM who self-reported practicing chemsex during their most recent sexual intercourse (defined as “chemsexers”) with other MSM, using five outcomes: increased 1/tobacco use, 2/alcohol use, and 3/other psychoactive drug use. 4/using psychotropic medication during the lockdown, and finally 5/psychological distress. …”
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Off-label prescription of psychiatric drugs by non-psychiatrist physicians in three general hospitals in Germany by Caroline Lücke, Jürgen M. Gschossmann, Teja W. Grömer, Sebastian Moeller, Charlotte E. Schneider, Aikaterini Zikidi, Alexandra Philipsen, Helge H. O. Müller

“…Abstract Background Off-label prescribing of psychoactive drugs is a common practice in psychiatry. Here, we sought to investigate the frequency of off-label prescribing in a population of hospitalized patients with a somatic illness who were also suffering from a psychiatric pathology. …”
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'I t’s not going to be a one size fits all': a qualitative exploration of the potential utility of three drug checking service models in Scotland by Hannah Carver, Danilo Falzon, Wendy Masterton, Bruce Wallace, Elizabeth V. Aston, Fiona Measham, Carole Hunter, Harry Sumnall, Rosalind Gittins, Fiona Raeburn, Vicki Craik, Saket Priyadarshi, Laura Rothney, Kira Weir, Tessa Parkes

“…Drug checking services allow individuals to submit presumed psychoactive drug samples for analysis, and then receive individualised feedback and counselling. …”
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Drogas e saúde na imprensa brasileira: uma análise de artigos publicados em jornais e revistas Drugs and health in the Brazilian press: an analysis of articles published in newspap... by Ana Regina Noto, Murilo C. Baptista, Silene T. Faria, Solange A. Nappo, José Carlos F. Galduróz, Elisaldo A. Carlini

“…<br>This article analyzes information recently published by the Brazilian press on the use of psychoactive drugs and its implications on health. A sample of 502 newspaper and magazine articles published in 1998 was researched using content analysis. …”
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Relationship between GABA-Ergic System and the Expression of Mephedrone-Induced Reward in Rats—Behavioral, Chromatographic and In Vivo Imaging Study by Olga Wronikowska-Denysiuk, Agnieszka Michalak, Anna Pankowska, Łukasz Kurach, Paulina Kozioł, Artur Łazorczyk, Katarzyna Kochalska, Katarzyna Targowska-Duda, Anna Boguszewska-Czubara, Barbara Budzyńska

“…Mephedrone is a psychoactive drug that increases dopamine, serotonin and noradrenaline levels in the central nervous system via interaction with transporters or monoamines. …”
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Therapeutic Potential of Cannabinoids on Tumor Microenvironment: A Molecular Switch in Neoplasia Transformation by Hamid A. Bakshi PhD, Hakkim L. Faruck PhD, Zeinab Ravesh PhD, Prawej Ansari PhD, J. M. A. Hannan PhD, Rina Hashimoto PhD, Kazuo Takayama PhD, Rabia Farzand PhD, Mohamed M. Nasef PhD, Adelaide Mensah PhD, Alaa A. A. Aljabali PhD, Vijay Mishra PhD, Nitin B. Charbe PhD, Rohit Goyal PhD, Poonam Negi PhD, Ángel Serrano-Aroca PhD, Bojlul Bahar PhD, Mohamed El-Tanani PhD, Aaron J. Courtenay PhD, Paul McCarron PhD, Iain G. Jack PhD, Murtaza M. Tambuwala PhD

“…Cannabinoids are a group of marker compounds found in Cannabis sativa L., more commonly known as marijuana, a psychoactive drug used since ancient times for pain management. …”
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Do women who consult with naturopaths or herbalists have a healthy lifestyle?: a secondary analysis of the Australian longitudinal study on women’s health by Amie Steel, Stefania Tiveron, Rebecca Reid, Jon Wardle, Holger Cramer, Jon Adams, David Sibbritt, Romy Lauche

“…Conclusions Consultations with a naturopath or herbalist are associated with positive health behaviours that are protective of internationally important non-communicable diseases. Psychoactive drug use is also reported among women visiting a naturopath or herbalist. …”
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A Structure-Activity Relationship Comparison of Imidazodiazepines Binding at Kappa, Mu, and Delta Opioid Receptors and the GABA_A Receptor by Guanguan Li, Amanda N. Nieman, Md Yeunus Mian, Nicolas M. Zahn, Brandon N. Mikulsky, Michael M. Poe, Kashi R. Methuku, Yongfeng Liu, James M. Cook, Douglas C. Stafford, Leggy A. Arnold

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Factores asociados al rendimiento académico en estudiantes de medicina Factors associated with academic performance in medical students by Alberto Vélez van Meerbeke, Claudia Natalí Roa González

“…Features of interfamilial violence, alcohol and cigarette consumption (but not psychoactive drug use) were detected. The results obtained in the differential and general learning aptitude tests (BADyGs) were low. …”
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