Dissecting Causal Associations of Diet-Derived Circulating Antioxidants with Six Major Mental Disorders: A Mendelian Randomization Study by Hao Zhao, Xue Han, Xuening Zhang, Lingjiang Li, Yanzhi Li, Wanxin Wang, Roger S. McIntyre, Kayla M. Teopiz, Lan Guo, Ciyong Lu

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The Effect of the Selective N-methyl-D-aspartate (NMDA) Receptor GluN2B Subunit Antagonist CP-101,606 on Cytochrome P450 2D (CYP2D) Expression and Activity in the Rat Liver and Bra... by Anna Haduch, Ewa Bromek, Renata Pukło, Joanna Jastrzębska, Przemysław Jan Danek, Władysława Anna Daniel

“…The CYP2D enzymes of the cytochrome P450 superfamily play an important role in psychopharmacology, since they are engaged in the metabolism of psychotropic drugs and endogenous neuroactive substrates, which mediate brain neurotransmission and the therapeutic action of those drugs. …”
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Clinical Application of Metformin Use in Anhui Province, China: A Cross-Sectional Study by Chen L, Chen Q, Chen X, Zhu P, Chen M, Wang W, Ye S, Zheng M

“…Li Chen,1,* Qin Chen,2 Xueping Chen,3,4 Pengli Zhu,5 Meinan Chen,6 Wei Wang,7,8 Shandong Ye,7,8 Mao Zheng7,8,* 1Department of Endocrinology, The Third Affiliated Hospital of Anhui Medical University (The First People’s Hospital of Hefei City), Hefei, People’s Republic of China; 2Department of Pharmacy, Taihe County People’s Hospital, Taihe, People’s Republic of China; 3Department of Pharmacy, Hefei Fourth People’s Hospital, Hefei, People’s Republic of China; 4Psychopharmacology Research Laboratory, Anhui Mental Health Center and Department of Pharmacy, Affiliated Psychological Hospital of Anhui Medical University, Hefei, People’s Republic of China; 5Department of Pharmacy, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People’s Republic of China; 6Ethics Committee on Medical Research, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People’s Republic of China; 7Department of Endocrinology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People’s Republic of China; 8Laboratory of Diabetes, Department of Endocrinology, The First Affiliated Hospital of USTC, Hefei, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shandong Ye; Mao Zheng, Department of Endocrinology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, People’s Republic of China, Tel +86 189 6378 9135 ; +86 13215603125, Fax +86 0551-62283524, Email ysd196406@163.com; zhengmao1999@foxmail.comPurpose: Given the importance of metformin, reasonable utilization is essential. …”
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Serum TSH Levels are Associated with Hyperactivity Behaviors in Children with Attention Deficit/Hyperactivity Disorder by Chen G, Gao W, Xu Y, Chen H, Cai H

“…Guanru Chen,1,* Wenfan Gao,2– 4,* Yayun Xu,5 Huiying Chen,1 Heping Cai1 1Department of Clinical Pharmacy, Anhui Provincial Children’s Hospital, Hefei, Anhui, People’s Republic of China; 2Psychopharmacology Research Laboratory, Affiliated Psychological Hospital of Anhui Medical University, Hefei, Anhui, People’s Republic of China; 3Department of Pharmacy, Hefei Fourth People’s Hospital, Hefei, Anhui, People’s Republic of China; 4Anhui Clinical Research Center for Mental Disorders, Anhui Mental Health Center, Hefei, Anhui, People’s Republic of China; 5Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, People’s Republic of China*These authors contributed equally to this workCorrespondence: Guanru Chen, Department of Clinical Pharmacy, Anhui Provincial Children’s Hospital, 39 Wangjiang Road, Hefei, 230000, People’s Republic of China, Email albertandy@163.comObjective: Previous studies indicated that maternal thyroid dysfunction increase the offspring’s risk for attention deficit/hyperactivity disorder (ADHD). …”
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Predicting Long-Term Cognitive Impairments in Survivors after Cardiac Arrest: A Systematic Review by Astrid Glimmerveen, Marlous Verhulst, Jeanine Verbunt, Caroline van Heugten, Jeannette Hofmeijer

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Differences in Next-Day Adverse Effects and Impact on Mood of an Evening of Heavy Alcohol Consumption between Hangover-Sensitive Drinkers and Hangover-Resistant Drinkers by Marlou Mackus, Aurora J. A. E. van de Loo, Renier H. P. van Neer, Sterre A. Vermeulen, Chantal Terpstra, Karel A. Brookhuis, Johan Garssen, Andrew Scholey, Joris C. Verster

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Use of Methylphenidate to Improve Cognition in Autism Spectrum Disorder (ASD) by S. Ashraf, A. Bachu, S. Srinivas, W. Tankersley, K. Shah

“…Journal of child and adolescent psychopharmacology 2020; 30(7), 414–426). There were no serious side effects or suicidality reported for low dose and a medium dose of MPH in ASD children assessed with Response Impressions and Side Effects Checklist-Kids (RISC-K), A 38-item parent rating scale (Kim, S. …”
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Medical Cannabis Use Patterns for Sleep Disorders in Australia: Results of the Cross-Sectional CAMS-20 Survey by Suraev A, Mills L, Abelev SV, Arkell TR, Lintzeris N, McGregor IS

“…Anastasia Suraev,1– 3 Llewellyn Mills,4,5 Sarah V Abelev,1 Thomas R Arkell,6 Nicholas Lintzeris,4,5,* Iain S McGregor1– 3,* 1The University of Sydney, Lambert Initiative for Cannabinoid Therapeutics, Sydney, NSW, Australia; 2The University of Sydney, Faculty of Science, School of Psychology, Sydney, NSW, Australia; 3The University of Sydney, Brain and Mind Centre, Sydney, NSW, Australia; 4Drug and Alcohol Services, South East Sydney Local Health District, Sydney, NSW, Australia; 5Department of Addiction Medicine, Faculty Medicine and Health, University of Sydney, Sydney, NSW, Australia; 6Centre for Human Psychopharmacology, Swinburne University of Technology, Hawthorn, VIC, Australia*These authors contributed equally to this workCorrespondence: Iain S McGregor, The University of Sydney, Lambert Initiative for Cannabinoid Therapeutics, Level 6, Building M02F, 94 Mallett Street Camperdown, Sydney, NSW, 2050, Australia, Tel +612 9351 0883, Email iain.mcgregor@sydney.edu.auIntroduction: Sleep disorders are the third most common indication for the prescription of medical cannabis products in Australia, after pain and anxiety. …”
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Safety and Efficacy of Drug Holidays for Women with Sexual Dysfunction Induced by Selective Serotonin Reuptake Inhibitors (SSRIs) Other than Fluoxetine: An Open-Label Randomized Cl... by Elham Lalegani, Negin Eissazade, Mohammadreza Shalbafan, Razieh Salehian, Seyed Vahid Shariat, Sanaz Askari, Laura Orsolini, Shiva Soraya

“…Selective serotonin reuptake inhibitors (SSRIs) are the cornerstone of psychopharmacology. However, they cause side effects such as sexual dysfunction, leading to the discontinuation of treatment. …”
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Peripheral Complement Factor-Based Biomarkers for Patients with First-Episode Schizophrenia by Cao Y, Xu Y, Xia Q, Shan F, Liang J

“…Yin Cao,1– 4 Yayun Xu,5– 7 Qingrong Xia,1– 4 Feng Shan,1– 4 Jun Liang1– 4 1Affiliated Psychological Hospital of Anhui Medical University, Hefei, People’s Republic of China; 2Department of Pharmacy, Hefei Fourth People’s Hospital, Hefei, People’s Republic of China; 3Psychopharmacology Research Laboratory, Anhui Mental Health Center, Hefei, People’s Republic of China; 4Anhui Clinical Research Center for Mental Disorders, Hefei, People’s Republic of China; 5Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, People’s Republic of China; 6Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, Anhui Medical University, Hefei, People’s Republic of China; 7The Key Laboratory of Anti-Inflammatory and Immune Medicines, Ministry of Education, Hefei, People’s Republic of ChinaCorrespondence: Jun Liang, Department of Pharmacy, Hefei Fourth People’s Hospital, Affiliated Psychological Hospital of Anhui Medical University, Anhui Mental Health Center, 316 Huangshan Road, Hefei, 230000, People’s Republic of China, Email amhcliangj@163.comObjective: Schizophrenia (SCZ) is a severe, protracted neurological disorder that causes disruptive conduct in millions of individuals globally. …”
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Epidemiology of classic psychedelic substances: results from a Norwegian internet convenience sample by Tor-Morten Kvam, Tor-Morten Kvam, Malin V. Uthaug, Malin V. Uthaug, Malin V. Uthaug, Kristoffer A. A. Andersen, Kristoffer A. A. Andersen, Birk Berggrav Refsum, Paula Aarseth Tunstad, Lowan Han Stewart, Henrik Børsting Jacobsen, Henrik Børsting Jacobsen, Cato Grønnerød

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Fluoxetine improves bone microarchitecture and mechanical properties in rodents undergoing chronic mild stress – an animal model of depression by Raymond W. Lam, Hee-Kit Wong, Ramruttun A. Kumarsing, Anna N. Chua, Roger C. Ho, Roger S. McIntyre, Cyrus S. Ho

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A proof of concept phase II study with the PDE-4 inhibitor roflumilast in patients with mild cognitive impairment or mild Alzheimer’s disease dementia (ROMEMA): study protocol of a... by Nina Possemis, Frans Verhey, Jos Prickaerts, Arjan Blokland, Inez Ramakers

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Task-based co-activation patterns reliably predict resting state canonical network engagement during development by Fengdan Ye, Robert Kohler, Bianca Serio, Sarah Lichenstein, Sarah W. Yip

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Misuse of Anticholinergic Medications: A Systematic Review by Stefania Chiappini, Alessio Mosca, Andrea Miuli, Francesco Maria Semeraro, Gianluca Mancusi, Maria Chiara Santovito, Francesco Di Carlo, Mauro Pettorruso, Amira Guirguis, John Martin Corkery, Giovanni Martinotti, Fabrizio Schifano, Massimo Di Giannantonio

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Potential efficacy of dopaminergic antidepressants in treatment resistant anergic-anhedonic depression results of the chronic anergic-anhedonic depression open trial – CADOT by Ludovic Christophe Dormegny-Jeanjean, Ludovic Christophe Dormegny-Jeanjean, Ludovic Christophe Dormegny-Jeanjean, Clément de Billy, Clément de Billy, Clément de Billy, Olivier Mainberger, Olivier Mainberger, Olivier Mainberger, Sébastien Weibel, Sébastien Weibel, Sébastien Weibel, Benoit Schorr, Benoit Schorr, Benoit Schorr, Alexandre Obrecht, Alexandre Obrecht, Lionel Landré, Fabrice Berna, Fabrice Berna, Jean-Baptiste Causin, Jean-Baptiste Causin, Jean-Baptiste Causin, Frederic Blanc, Frederic Blanc, Vlad Danila, Vlad Danila, Mihaela Tomsa, Mihaela Tomsa, Geraldine Pfleger, Geraldine Pfleger, Camille Meyer, Camille Meyer, Camille Meyer, Ilia Humbert, Ilia Humbert, Ilia Humbert, Hervé Javelot, Hervé Javelot, Guillaume Meyer, Guillaume Meyer, Gilles Bertschy, Gilles Bertschy, Gilles Bertschy, Jack Rene Foucher, Jack Rene Foucher, Jack Rene Foucher, Jack Rene Foucher

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Nonadherence by Serum Drug Analyses in Resistant Hypertension: 7‐Year Follow‐Up of Patients Considered Adherent by Directly Observed Therapy by Lene V. Halvorsen, Ola U. Bergland, Camilla L. Søraas, Anne Cecilie K. Larstorp, Ulla Hjørnholm, Vibeke N. Kjær, Marianne K. Kringen, Per‐Erik Clasen, Renate Haldsrud, Sverre E. Kjeldsen, Morten Rostrup, Fadl Elmula M. Fadl Elmula, Mimi S. Opdal, Aud Høieggen

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Efficacy of Psychosocial and Psychological Interventions in Addition to Drug Therapy to Improve Global Functioning of Inpatients with Schizophrenia Spectrum and Mood Disorders: A R... by Chiappini S, Di Carlo F, Mosca A, d'Andrea G, Di Paolo M, Lorenzini C, Lupica MG, Sampogna G, Pettorruso M, Fiorillo A, Martinotti G

“…D’Annunzio’ University, Chieti, Italy; 2Psychopharmacology, Drug Misuse and Novel Psychoactive Substances Research Unit, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK; 3Department of Psychiatry, University of Campania “L. …”
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Prevalence and trajectories of neuropsychological post-COVID-19 symptoms in initially hospitalized patients by Simona Klinkhammer, Annelien A. Duits, Janneke Horn, Arjen J.C. Slooter, Esmée Verwijk, Susanne van Santen, Johanna M.A. Visser-Meily, Caroline van Heugten

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Prelimbic Cortical Stimulation Induces Antidepressant-like Responses through Dopaminergic-Dependent and -Independent Mechanisms by Sharafuddin Khairuddin, Wei Ling Lim, Luca Aquili, Ka Chun Tsui, Anna Chung-Kwan Tse, Shehani Jayalath, Ruhani Varma, Trevor Sharp, Abdelhamid Benazzouz, Harry Steinbusch, Arjan Blokland, Yasin Temel, Lee Wei Lim

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