Patent Ductus Arteriosus Stent Versus Surgical Aortopulmonary Shunt for Initial Palliation of Cyanotic Congenital Heart Disease with Ductal‐Dependent Pulmonary Blood Flow: A System... by Stephanie Y. Tseng, Vien T. Truong, Daniel Peck, Sneha Kandi, Samuel Brayer, Don P. Jason, Wojciech Mazur, Garick D. Hill, Awais Ashfaq, Bryan H. Goldstein, Tarek Alsaied

“…There was no difference in pulmonary artery growth or hazard of unplanned reintereventions. …”
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Effect of acetazolamide on pulmonary vascular haemodynamics in patients with COPD going to altitude: a randomised, placebo-controlled, double-blind trial by Mona Lichtblau, Stéphanie Saxer, Laura Mayer, Ulan Sheraliev, Maamed Mademilov, Michael Furian, Aline Buergin, Philipp M. Schweiwiller, Simon R. Schneider, Felix C. Tanner, Talant Sooronbaev, Konrad E. Bloch, Silvia Ulrich

“…We investigated haemodynamic changes in lowlanders with COPD ascending to 3100 m and evaluated whether preventive acetazolamide treatment would attenuate the altitude-induced increase in pulmonary artery pressure (PAP). Methods In this randomised, placebo-controlled, double-blind, parallel-group trial, patients with COPD Global Initiative for Chronic Obstructive Lung Disease grades 2–3 who were living <800 m and had peripheral oxygen saturation (SpO2) >92% and arterial carbon dioxide tension <6 kPa were randomised to receive either acetazolamide (125–250 mg·day−1) or placebo capsules, starting 24 h before ascent from 760 m and during a 2-day stay at 3100 m. …”
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Pulmonary vascular reactivity in growth restricted fetuses using computational modelling and machine learning analysis of fetal Doppler waveforms by Kilian Vellvé, Patricia Garcia-Canadilla, Mariana Nogueira, Lina Youssef, Angela Arranz, Ayako Nakaki, David Boada, Isabel Blanco, Rosa Faner, Francesc Figueras, Àlvar Agustí, Eduard Gratacós, Francesca Crovetto, Bart Bijnens, Fàtima Crispi

“…Delta changes of the main pulmonary artery VTI and intrapulmonary artery pulsatility index before and after hyperoxygenation were significantly greater in FGR when compared with controls. …”
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Pregnancy outcomes in women with pulmonary hypertension: a retrospective study in China by Chengtian Lv, Yuwen Huang, Guangyuan Liao, Lichan Wu, Dunjin Chen, Yuanmei Gao

“…Results Among the 154 pregnant women with PH, 6 (3.9%) had idiopathic pulmonary arterial hypertension (iPAH), 41 (26.6%) had pulmonary arterial hypertension (PAH) associated with congenital heart disease (CHD-PAH), 45 (29.2%) had PAH related to other diseases (oPAH), and 62 (40.3%) had PH related to left heart disease (LHD-PH). …”
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Early Results of the Persian Registry of Cardiovascular Disease/Congenital Heart Disease (PROVE/CHD) in Isfahan by Ali Reza Ahmadi, Mohammad Reza Sabri, Zohreh Sadat Navabi, Mehdi Ghaderian, Bahar Dehghan, Chehreh Mahdavi, Somaieh Khodarahmi

“…The palliative surgeries mainly consisted of the Glenn shunt (9.0%) and pulmonary artery banding (3.6%). Conclusion: The PROVE/CHD Registry collects data on pediatric patients with CHD. …”
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Short‐term outcomes of heart transplant patients bridged with Impella 5.5 ventricular assist device by Osama Haddad, Basar Sareyyupoglu, Rohan M. Goswami, Macit Bitargil, Parag C. Patel, Samuel Jacob, Magdy M. El‐Sayed Ahmed, Juan Carlos Leoni Moreno, Daniel S. Yip, Kevin Landolfo, Si M. Pham

“…During Impella support, patients had improved renal function with median creatinine serum level of 1.55 mg/dL decreased to 1.25 (P = 0.007), pulmonary artery pulsatility index scores increased from 2.56 (0.86–10) to 4.2 (1.3–10) (P = 0.048), and right ventricular function improved (P = 0.003). …”
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Secondary polycythemia in chronic obstructive pulmonary disease: prevalence and risk factors by Jingzhou Zhang, Dawn L. DeMeo, Edwin K. Silverman, Barry J. Make, R. Chad Wade, J. Michael Wells, Michael H. Cho, Brian D. Hobbs

“…We used logistic regression to evaluate the association of polycythemia with age, sex, race, altitude, current smoking status, spirometry, diffusing capacity for carbon monoxide (DLCO), quantitative chest CT measurements (including emphysema, airway wall thickness, and pulmonary artery to aorta diameter ratio), resting hypoxemia, exercise-induced hypoxemia, and long-term oxygen therapy. …”
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Validation of cardiac index measured by four‐dimensional cardiac magnetic resonance flow against the invasively measured cardiac index in patients with pulmonary hypertension by Soha Romeih, Fatma Elkafrawy, Mahmoud Shaaban, Ahmed Hassan, Irini Samuel, Micheal Gergis, Wesam El mozy, Magdi Yacoub

“…All patients had helical right‐sided flow with vortex formation; the mean vortex diameter was 29 ± 7 mm, occupying 69% of the main pulmonary artery (MPA) lumen. MPA was dilated (42 ± 9 mm). …”
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Depressed right ventricular systolic function in heart failure due to constrictive pericarditis by Veena Raizada, Kimi Sato, Alaa Alashi, Arnav Kumar, Deborah Kwon, Jay Ramchand, Amy Dillenbeck, Ross E. Zumwalt, Adarsh S. Vangala, Tyler D. Earley, Allan Klein

“…Additionally, in 40 adults with clinical heart failure and 40 healthy adults (controls), sf of both ventricles was examined by echocardiography, including strain measurements, and biventricular diastolic filling and pulmonary artery pressures were assessed by cardiac catheterization. …”
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Moxidectin steady state prior to inoculation protects cats from subsequent, repeated infection with Dirofilaria immitis by Susan E Little, Joe A Hostetler, Jennifer E Thomas, Keith L Bailey, Anne W Barrett, Kaylynn Gruntmeir, Jeff Gruntmeir, Lindsay A Starkey, Chris Basel, Byron L Blagburn

“…Histologic lesions characteristic of D. immitis infection, including intimal and medial thickening of the pulmonary artery, were present in every cat with D. immitis antibodies (6/6), although adult D. immitis were confirmed in only 5/6 antibody-positive cats at necropsy. …”
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Continuous Aspiration Thrombectomy in High- and Intermediate-High-Risk Pulmonary Embolism in Real-World Clinical Practice by Aleksander Araszkiewicz, Sylwia Sławek-Szmyt, Stanisław Jankiewicz, Bartosz Żabicki, Marek Grygier, Tatiana Mularek-Kubzdela, Zbigniew Krasiński, Maciej Lesiak

“…Complete or nearly complete clearance of pulmonary arteries was achieved in nine patients (64.3%), whereas partial clearance was achieved in five (35.7%). …”
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Right ventricular functional recovery assessment with stress echocardiography and cardiopulmonary exercise testing after pulmonary embolism: a pilot prospective multicentre study by Luke S Howard, Wei Li, James Anderson, Sudhir Wahi, Colm McCabe, Laura C Price, Gregory J Keir, John Upham, Khoa Tran, Chinthaka Bhagya Samaranayake, Sean Nguyen, Myo Lwin, Stephen Wort

“…RV systolic dysfunction and RV to pulmonary artery (PA) uncoupling assessed by stress echocardiography was seen in 29.2% (n=7) patients and associated with increased ventilatory inefficiency (V̇E/V̇CO2 slope 47.6 vs 32.4, p=0.03), peak exercise oxygen desaturation (93.2% vs 98.4%, p=0.01) and reduced peak oxygen pulse (p=0.036) compared with controls. …”
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Right Ventricle Strain Assessed by 2-Dimensional Speckle Tracking Echocardiography (2D-STE) to Evaluate Pulmonary Hypertension in Dogs with <i>Dirofilaria immitis</i> by Jorge Isidoro Matos, Sara Nieves García-Rodríguez, Noelia Costa-Rodríguez, Alicia Caro-Vadillo, Elena Carretón, José Alberto Montoya-Alonso

“…PH was identified in 41% of the infected dogs following the American College of Veterinary Internal Medicine (ACVIM) guidelines, based on the peak tricuspid regurgitation velocity to calculate the tricuspid regurgitation pressure gradient (TRPG), while other routine measurements were used, including the right pulmonary artery distensibility index (RPADi). The 2D-STE mode measurements were determined using Right Ventricular Automated Function Imaging (RV AFI^®) software. …”
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Impact of bridging with left ventricular assist device on right ventricular function following heart transplantation by Annika Ingvarsson, Grunde Gjesdal, Saeideh Borgenvik, Anna Werther Evaldsson, Johan Waktare, Oscar Braun, Gustav J. Smith, Anders Roijer, Göran Rådegran, Carl Meurling

“…Abstract Aims Patients awaiting orthotopic heart transplantation (OHT) can be bridged utilizing a left ventricular assist device (LVAD) that reduces left ventricular filling pressures, decreases pulmonary artery wedge pressure, and maintains adequate cardiac output. …”
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Prevalence and risk prediction value of tricuspid regurgitation by echocardiography in precapillary pulmonary hypertension by Jiahui Li, Aili Li, Yanan Zhai, Lei Li, Yu Zhang, Aihong Chen, Xincao Tao, Qian Gao, Wanmu Xie, Zhenguo Zhai

“…The impact of TR severity on pulmonary artery pressure (PAP) assessment and clinical risk stratification in precapillary PH remains unclear. …”
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A nonsense variant in FBN1 caused autosomal dominant Marfan syndrome in a Chinese family: a case report by Yuping Niu, Sexin Huang, Zeyu Wang, Peiwen Xu, Lijuan Wang, Jie Li, Ming Gao, Xuan Gao, Yuan Gao

“…Echocardiography showed dilatation of the ascending aorta and main pulmonary artery, mitral regurgitation (mild), tricuspid regurgitation (mild), and abnormal left ventricular filling. …”
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Comparison of Repetitive Cardiac Output Measurements at Rest and End-Exercise by Direct Fick Using Pulse Oximetry vs. Blood Gases in Patients With Pulmonary Hypertension by Milos Duknic, Milos Duknic, Mona Lichtblau, Mona Lichtblau, Stéphanie Saxer, Stéphanie Saxer, Charlotte Berlier, Charlotte Berlier, Simon R. Schneider, Simon R. Schneider, Esther I. Schwarz, Esther I. Schwarz, Arcangelo F. Carta, Arcangelo F. Carta, Michael Furian, Michael Furian, Konrad E. Bloch, Konrad E. Bloch, Silvia Ulrich, Silvia Ulrich

“…Background: Exact and simultaneous measurements of mean pulmonary artery pressure (mPAP) and cardiac output (CO) are crucial to calculate pulmonary vascular resistance (PVR), which is essential to define pulmonary hypertension (PH). …”
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Automatic segmentation of the great arteries for computational hemodynamic assessment by Javier Montalt-Tordera, Endrit Pajaziti, Rod Jones, Emilie Sauvage, Rajesh Puranik, Aakansha Ajay Vir Singh, Claudio Capelli, Jennifer Steeden, Silvia Schievano, Vivek Muthurangu

“…This study aims to develop and validate a machine learning (ML) method for segmentation of the aorta and pulmonary arteries for CFD studies. Methods 90 CHD patients were retrospectively selected for this study. 3D CMR images were manually segmented to obtain ground-truth (GT) background, aorta and pulmonary artery labels. …”
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Exercise stress echocardiography shows impaired left ventricular function after hospitalization with COVID‐19 without overt myocarditis: A pilot study by Robert E. Goldstein, Edward A. Hulten, Thomas B. Arnold, Victoria M. Thomas, Andrew Heroy, Erika N. Walker, Keiko Fox, Hyun Lee, Joya Libbus, Bethelhem Markos, Maureen N. Hood, Travis E. Harrell, Mark C. Haigney

“…RP peak heart rate was significantly higher (172 ± 18 vs. 153 ± 20); peak systolic blood pressure trended higher (192 ± 31 vs. 178 ± 19). Pulmonary artery systolic pressures among RP remained normal. …”
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MicroRNA‐30d and ‐483‐3p for bi‐ventricular remodelling and miR‐126‐3p for pulmonary hypertension in advanced heart failure by Alessia Gallo, Valentina Agnese, Sergio Sciacca, Cesare Scardulla, Manlio Cipriani, Michele Pilato, Jae K. Oh, Salvatore Pasta, Joseph Maalouf, Pier Giulio Conaldi, Diego Bellavia

“…Conclusions In patients with DCM, few miRNAs are co‐expressed in serum and tissue: They are related to LV remodelling (miR‐30d), post‐capillary pulmonary artery pressure (miR‐126‐3p), and right ventricular remodelling/filling pressures (miR‐483‐3p). …”
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