In vitro efficacy of antimalarial drugs against Plasmodium vivax on the western border of Thailand. by Chotivanich, K, Udomsangpetch, R, Chierakul, W, Newton, P, Ruangveerayuth, R, Pukrittayakamee, S, Looareesuwan, S, White, N

“…Compared with P. falciparum in this area, P. vivax was more sensitive to chloroquine and artesunate, equally sensitive to quinine, and more resistant to mefloquine.…”

Treatment of malaria in pregnancy by Tarning, J

“…The drugs of choice are quinine and the artemisinins. Studies are urgently needed to define the best therapeutic options and to develop new treatments, especially in Africa where drug resistance already compromises all strategies of control.…”

Pengobatan malaria secara rasional by Perpustakaan UGM, i-lib

“…For all species except chloroquine resistant faksparum should be given chloroquine combined with primaquine. Quinine and Fansidar/ Maloprim in a combination is recommended against chloroquine resistant fakiparum. …”

Suppressive effects of the anti-oxidant N-acetylcysteine on the anti-malarial activity of artesunate. by Arreesrisom, P, Dondorp, A, Looareesuwan, S, Udomsangpetch, R

“…We studied the interaction between NAC and artesunate as well as quinine in an in vitro drug sensitivity assay. Combination with NAC reduced the parasitocidal effect of artesunate only within the first 6 h of incubation, whereas no interaction was observed with quinine. …”

High rate of Plasmodium vivax relapse following treatment of falciparum malaria in Thailand. by Looareesuwan, S, White, N, Chittamas, S, Bunnag, D, Harinasuta, T

“…The time to vivax relapse was significantly longer after mefloquine treatment (median 47 days, range 30-65) than after quinine or quinidine treatment (21 days, 15-36; p less than 0.0001). …”

A nationwide survey of the quality of antimalarials in retail outlets in Tanzania. by Harparkash Kaur, Catherine Goodman, Eloise Thompson, Katy-Anne Thompson, Irene Masanja, S Patrick Kachur, Salim Abdulla

“…Nearly one quarter (23.8%) of quinine tablets did not comply within the tolerance limits of the dissolution and quantification analysis. …”
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EVALUASI RESPON PENGOBATAN MALARIA DI RSUD SUMBAWA by , Tri Widiastuti, , Prof. Dr. Mustofa, M.Kes., Apt.

“…There is one vivax malaria patients treated with quinine + primaquine produces ACPR response. Patients with falciparum malaria there are 7 people. …”

EVALUASI RESPON PENGOBATAN MALARIA DI RSUD SUMBAWA by , Tri Widiastuti, , Prof. Dr. Mustofa, M.Kes., Apt.

“…There is one vivax malaria patients treated with quinine + primaquine produces ACPR response. Patients with falciparum malaria there are 7 people. …”

Dihydroartemisinin-piperaquine treatment of multidrug resistant falciparum and vivax malaria in pregnancy by Poespoprodjo, JR, Fobia, W, Kenangalem, E, Lampah, D, Sugiarto, P, Tjitra, E, Anstey, N, Price, R

“…However in the first trimester 63% (5/8) of women treated with oral DHP miscarried compared to 2.6% (1/38) of those receiving oral quinine; p<0.001. Of the 847 women admitted for delivery those reporting a history of malaria during their pregnancy who had been treated with quinine-based regimens rather than DHP had a higher risk of malaria at delivery (adjusted OR = 1.56 (95%CI 0.97–2.5), p = 0.068) and perinatal mortality (adjusted OR = 3.17 [95%CI: 1.17–8.60]; p = 0.023). …”

Hypoglycaemia and counterregulatory hormone responses in severe falciparum malaria: treatment with Sandostatin. by Phillips, R, Looareesuwan, S, Molyneux, M, Hatz, C, Warrell, D

“…In volunteer studies a single intramuscular injection of Sandostatin (100 micrograms) suppressed quinine-induced hyperinsulinaemia within 15 min; this effect was maintained for 6 h. …”

Management of Plasmodium falciparum malaria. by Phillips, R

“…There are few alternative drugs available. Quinine remains effective against P. falciparum in Southeast Asia. …”

Sex chromosome and gonadal hormone contributions to binge-like and aversion-resistant ethanol drinking behaviors in Four Core Genotypes mice by Elizabeth A. Sneddon, Elizabeth A. Sneddon, Brianna M. Masters, Brianna M. Masters, Kiara D. Ream, Kiara D. Ream, Kaila A. Fennell, Kaila A. Fennell, Jenelle N. DeMedio, Jenelle N. DeMedio, Miranda M. Cash, Miranda M. Cash, Brynn P. Hollingsworth, Brynn P. Hollingsworth, Sai Pandrangi, Sai Pandrangi, Chloe M. Thach, Chloe M. Thach, Haifei Shi, Haifei Shi, Anna K. Radke, Anna K. Radke

“…When increasing concentrations of quinine (100–500 μM) were added to the solution, FCG mice were insensitive to quinine-punished EtOH responding, regardless of sex chromosome complement. …”
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دراسة أوّلية عن توزّع العَمَه الذوقي الطبيعي عند فئات عمرية مختارة من المجتمع السوري (طلاب المرحلة الجامعية)... by حسن ميهوب

“…Threshold concentrations of the following solutions were used: sucrose, sodium chloride, citric acid, and quinine. Tests have showed the presence of hypogeusia for three tastes as follows: 34% of individuals were with the hypogeusia for the sweet taste (sucrose), 32% for salty taste (sodium chloride), and 19% for bitter taste (quinine). …”
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دراسة أوّلية عن توزّع العَمَه الذوقي الطبيعي عند فئات عمرية مختارة من المجتمع السوري (طلاب المرحلة الجامعية)... by حسن ميهوب

“…Threshold concentrations of the following solutions were used: sucrose, sodium chloride, citric acid, and quinine. Tests have showed the presence of hypogeusia for three tastes as follows: 34% of individuals were with the hypogeusia for the sweet taste (sucrose), 32% for salty taste (sodium chloride), and 19% for bitter taste (quinine). …”
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Common Molecular Targets of a Quinolone Based Bumped Kinase Inhibitor in <i>Neospora caninum</i> and <i>Danio rerio</i> by Joachim Müller, Nicoleta Anghel, Dennis Imhof, Kai Hänggeli, Anne-Christine Uldry, Sophie Braga-Lagache, Manfred Heller, Kayode K. Ojo, Luis-Miguel Ortega-Mora, Wesley C. Van Voorhis, Andrew Hemphill

“…Similar to the first-generation antiprotozoal drug quinine, some BKIs have a quinoline core structure. …”
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Management of severe malaria. by Warrell, D

“…At dispensaries, clinics or hospitals, where intramuscular or intravenous administration of antimalarial drugs is possible, quinine and artemisinin derivatives are the treatments of choice. …”

The effects of mefloquine treatment in pregnancy. by Nosten, F, Vincenti, M, Simpson, J, Yei, P, Thwai, K, de Vries, A, Chongsuphajaisiddhi, T, White, N

“…Of 3,587 pregnancies investigated, 208 (5.8%) were exposed to mefloquine, 656 (18.3%) to quinine only, and 909 (25.3%) to other antimalarials, and 2,470 (68.9%) had no documented malaria. …”

Reduced menthol sensitivity in a prodromal Parkinson’s disease model induced by intranasal rotenone treatment by Hajime Sato, Keitaro Satoh, Kazunori Nozaki, Misato Yugawa, Takafumi Kato, Hiroki Toyoda, Ayano Katagiri, Naoto Suda, Kazunori Adachi

“…The correlation between the licks for quinine-HCl and that for menthol was increased after rotenone treatment. …”
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Pregnancy outcomes after first-trimester treatment with artemisinin derivatives versus non-artemisinin antimalarials: a systematic review and individual patient data meta-analysis by Saito, M, McGready, R, Tinto, H, Rouamba, T, Mosha, D, Rulisa, S, Kariuki, S, Desai, M, Manyando, C, Njunju, EM, Sevene, E, Vala, A, Augusto, O, Clerk, C, Were, E, Mrema, S, Kisinza, W, Byamugisha, J, Kagawa, M, Singlovic, J, Yore, M, van Eijk, AM, Mehta, U, Stergachis, A, Hill, J, Stepniewska, K, Gomes, M, Guérin, PJ, Nosten, F, Ter Kuile, FO, Dellicour, S

“…If artemether–lumefantrine is unavailable, other ACTs (except artesunate–sulfadoxine–pyrimethamine) should be preferred to quinine. Continued active pharmacovigilance is warranted. …”

Potential of DNA Intercalating Alkaloids and Other Plant Secondary Metabolites against SARS-CoV-2 Causing COVID-19 by Michael Wink

“…These are DNA intercalators such as sanguinarine, berberine, emetine and other isoquinoline alkaloids, ß-carboline, and quinoline alkaloids such as quinine, cinchonine, dictamine and skimmianine. The DNA intercalators stabilize double-stranded nucleic acids and inhibit the replication, transcription, and translation of genetic material. …”
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