Lactic acidosis and hypoglycaemia in children with severe malaria: pathophysiological and prognostic significance. by Krishna, S, Waller, D, ter Kuile, F, Kwiatkowski, D, Crawley, J, Craddock, C, Nosten, F, Chapman, D, Brewster, D, Holloway, P

“…Admission blood venous glucose concentrations were lower in fatal cases than survivors (3.2 mmol/L, vs. 5.8 mmol/L; P < 0.0001). Treatment with quinine was associated with significantly more episodes of post-admission hypoglycaemia when compared with artemether or chloroquine. …”

The effects of multiplication and synchronicity on the vascular distribution of parasites in falciparum malaria. by White, N, Chapman, D, Watt, G

“…This suggests that the spleen is relatively inactive during the rising phase of the infection. Quinine treatment did not prevent sequestration but did stop subsequent multiplication.…”

Diagnosis, clinical presentation, and in-hospital mortality of severe malaria in HIV-coinfected children and adults in Mozambique. by Hendriksen, I, Ferro, J, Montoya, P, Chhaganlal, K, Seni, A, Gomes, E, Silamut, K, Lee, S, Lucas, M, Chotivanich, K, Fanello, C, Day, N, White, N, von Seidlein, L, Dondorp, A

“…METHODS: HIV status was assessed prospectively in hospitalized parasitemic adults and children with severe malaria in Beira, Mozambique, as part of a clinical trial comparing parenteral artesunate versus quinine (ISRCTN50258054). Clinical signs, comorbidity, complications, and disease outcome were compared according to HIV status. …”

Determination of paraldehyde by gas chromatography in whole blood from children. by Githiga, I, Muchohi, SN, Ogutu, B, Newton, C, Otieno, G, Gitau, E, Kokwaro, G

“…There was no interference from other drugs concurrently used in children with severe malaria, such as anticonvulsants (diazepam, phenytoin, phenobarbitone), antipyretics/analgesics (paracetamol and salicylate), antibiotics (gentamicin, chloramphenicol, benzyl penicillin) and antimalarials (chloroquine, quinine, proguanil, cycloguanil, pyrimethamine and sulfadoxine). …”

The 1996 Runme Shaw Memorial Lecture: malaria--past, present and future. by Warrell, D

“…Improvements in the chemotherapy of life-threatening falciparum malaria with chloroquine and quinine have been countered by the emergence of resistant strains. …”

Fevers in the garden: a history of malaria in colonial Assam from 1826 - 1939 by Friederich, E

“…Exploring anti-malarial measures in the province and the relationship between the creation of medical knowledge and public health praxis, this project touches on the topics of colonial ‘development’, quinine, mosquito control measures, and epidemiology. …”

Elevation of the Blood Glucose Level is Involved in an Increase in Expression of Sweet Taste Receptors in Taste Buds of Rat Circumvallate Papillae by Moemi Iwamura, Risa Honda, Kazuki Nagasawa

“…Under streptozotocin (STZ)-induced diabetes mellites (DM) conditions, the protein expression levels of T1R2 and T1R3 in CP were higher than those under control conditions, and these DM rats exhibited increased lick ratios in a low sucrose concentration range in a brief access test with a mixture of sucrose and quinine hydrochloride (QHCl). These findings indicate that the elevation of blood glucose level is a regulator for an increase in sweet taste receptor protein expression in rat CP, and such alteration in STZ-induced DM rats is involved in enhancement of their sweet taste sensitivity.…”
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The impact of solvent selection on the characteristics of niosome nanoparticles prepared by microfluidic mixing by Mohammad A. Obeid, Saja Haifawi, Ibrahim Khadra

“…The apparent encapsulation efficiency of quinine as a model hydrophobic drug was subsequently shown to be significantly (p < 0.05) affected by the type of the organic solvent used to prepare the niosomes, while the impact of the organic solvent had less impact on the apparent encapsulation of atenolol as a model hydrophilic drug.…”
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Mice expressing a "hyper-sensitive" form of the CB1 cannabinoid receptor (CB1) show modestly enhanced alcohol preference and consumption. by David J Marcus, Angela N Henderson-Redmond, Maciej Gonek, Michael L Zee, Jill C Farnsworth, Randa A Amin, Mary-Jeanette Andrews, Brian J Davis, Ken Mackie, Daniel J Morgan

“…S426A/S430A mutants and wild-type mice show similar taste preference for sucrose and quinine, exhibit normal sensitivity to the hypothermic and ataxic effects of ethanol, and have normal blood ethanol concentrations following administration of ethanol. …”
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Assessing the effects of native and alien plant ash on mosquito abundance by Vincent T. Netshituni, Ross N. Cuthbert, Farai Dondofema, Tatenda Dalu

“…Here, we investigated mosquito colonization in water treated with ash from native plants [quinine tree (Rauvolfia caffra), Transvaal milk plum (Englerophytum magalismontanum), apple leaf (Philenoptera violacea)] and invasive alien plants [i.e., lantana (Lantana camara), guava (Psidium guajava), red river gum (Eucalyptus camaldulensis)] in containers at two ash concentrations (i.e., 1, 2 g/L). …”
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Sharpless Asymmetric Dihydroxylation: An Impressive Gadget for the Synthesis of Natural Products: A Review by Aqsa Mushtaq, Ameer Fawad Zahoor, Muhammad Bilal, Syed Makhdoom Hussain, Muhammad Irfan, Rabia Akhtar, Ali Irfan, Katarzyna Kotwica-Mojzych, Mariusz Mojzych

“…Sharpless asymmetric dihydroxylation is an important reaction in the enantioselective synthesis of chiral vicinal diols that involves the treatment of alkene with osmium tetroxide along with optically active quinine ligand. Sharpless introduced this methodology after considering the importance of enantioselectivity in the total synthesis of medicinally important compounds. …”
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Sustainable Landuse Model at Upper Cikapundung River – North Bandung by Darsiharjo Darsiharjo

“…The rate of occured erosion in dry land, pine forest and plantation of quinine have is abysmal of permissible erosion, while in natural forest, rice field, and grass land still is normal. …”
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Iatrogenic retractile quadriceps fibrosis within children in Benin: Epidemiological, clinical, therapeutical aspects by A S Gbenou, G T Kpadonou, A M Fiogbe, E Zoumenou, M J Alao

“…Background: In tropical countries, iatrogenic retractile quadriceps fibrosis (IRQF), the cause of walking handicap in children, is often the result of intraquadricipital injection of quinine salts. The aim of this review was to analyse the epidemiological, clinical, therapeutic aspects and outcome of IRQF in children admitted in three hospitals in Benin Republic. …”
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Awareness on the Prevention and Treatment of Malaria among Residents in Abraka, Delta State, Nigeria by K.E. Edje, T.M.E. Daubry, L.U. Nwankwo, E.G. Moke, E.O. Erhirhie, O. Enaigbe

“…A greater percent (30%) commonly used artesunate in treating malaria, while 25% took Coartem® (artemether/lumefantrine), 23% took Lonart®  (artemether/lumefantrine), 10% took quinine and 12% had other drugs they took for the treatment of malaria. …”
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Severe Malaria with a Rare Tetrad of Blackwater Fever, Acute Renal Failure, Disseminated Intravascular Coagulopathy, and Acute Acalculous Cholecystitis by Hira Hanif, Biraj Shrestha, Salina Munankami, Manish Shrestha, Bidhya Poudel, Roopika Reddy, Syed Jaleel, Debra Powell

“…Blackwater fever (BWF) is a severe clinical syndrome occurring as a complication of malarial infection characterized by intravascular hemolysis, hemoglobinuria, and acute renal failure in people exposed to Plasmodium falciparum and, to some extent, in people who were exposed to medications like quinine and mefloquine. The exact pathogenesis of classic BWF remains unclear. …”
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Natural and Synthetic Pyrethrins Act as Feeding Deterrents against the Black Blowfly, <i>Phormia regina</i> (Meigen) by Takeshi Kojima, Seiji Yamato, Shinichi Kawamura

“…Feeding bouts were interrupted by intensive grooming of the proboscis at the deterring concentration, but no such grooming was observed to occur while feeding on the unpalatable tastants—NaCl, quinine, and tartaric acid. The underlying mode of action for the feeding deterrence of pyrethrins at sub-lethal concentrations probably occurs on the fly oral gustatory system, while differing from that of unpalatable tastants. …”
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The Biochemistry, Toxicology, and Uses of the Pharmacologically Active Phytochemicals: Alkaloids, Terpenes, Polyphenols, and Glycosides by Chinaza Godswill Awuchi

“…Alkaloids have a range of pharmacological activities such as antiasthma (e.g. ephedrine), anticancer (e.g. homoharringtonine), antimalarial (e.g. quinine). Other alkaloids possess stimulant (e.g. cocaine, caffeine, theobromine, nicotine) and psychotropic activities (e.g. psilocin), and have been widely used as recreational drugs or in entheogenic rituals. …”
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Analisis Kualitatif dan Kuantitatif Metabolit Sekunder Ekstrak Etanol Buah Okra (Abelmoschus esculentus L. Moench) dengan Metode Spektrofotometri UV-Vis by Joni Tandi, Bella Melinda, Anita Purwantari, Agustinus Widodo

“…Qualitative analysis of alkaloids using test parameters of total alkaloids equivalent to quinine, flavonoid using parameter of total flavonoids equivalent to quercetin, saponin using parameters of standard saponins total from the Quillaja Bark, and tannin using test parameters of total tannins equivalent to tannic acid. …”
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Constitutive Genetic Deletion of <i>Hcn1</i> Increases Alcohol Preference during Adolescence by Michael C. Salling, Neil L. Harrison

“…Here, we show that the genetic deletion of <i>Hcn1</i> causes an increase in alcohol preference on intermittent 2-bottle choice task in homozygous null (HCN1<i>^−/−</i>) male mice compared to wild-type littermates without affecting saccharine or quinine preference. The targeted viral deletion of HCN1 in pyramidal neurons of the medial prefrontal cortex resulted in a gradual loss of <i>Hcn1</i> expression and a reduction in I_h magnitude during adolescence, however, this did not significantly affect alcohol consumption or preference. …”
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DETECTION OF ALKALOID, FLAVONOID, AND TERPENOID COMPOUNDS IN BREAD (Artocarpus communis Forst.) LEAVES AND PULPS by Kristanti, Handriani, Tunjung, Woro Anindito Sri

“…Reference compounds used for alkaloid is quinine, rutine for the flavonoid, and terpeniol for terpenoid. …”
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