Artemisinin derivatives versus quinine for cerebral malaria in African children: a systematic review by Hmwe Hmwe Kyu, Eduardo Fernández

“…Seven trials compared artemether with quinine (1220 children), and two compared arteether with quinine (194 children). …”
Get full text

Development and Optimization of a Highly Sensitive Sensor to Quinine-Based Saltiness Enhancement Effect by Yifei Jing, Kentaro Watanabe, Tatsukichi Watanabe, Shunsuke Kimura, Kiyoshi Toko

“…Logarithmic responses have been found on both NaCl samples and quinine-added NaCl samples. The findings indicate the usage of lipid/polymer membranes on novel taste sensors to evaluate the saltiness enhancement effect accurately.…”
Get full text

Comparison of the efficacy of artesunate-amodiaquine with quinine ... clindamycin for treatment of uncomplicated falciparum malaria in children by Purnama Fitri, Armila Armila, Munar Lubis, Syahril Pasaribu, Chairuddin P. Lubis

“…Clindamycin in combination with quinine is also a safe and effective treatment for multidrug-resistant P. falciparum malaria. …”
Get full text

Diffusion of Quinine with Ethanol as a Co-Solvent in Supercritical CO₂ by Yury Gaponenko, Aliaksandr Mialdun, Valentina Shevtsova

Subjects: Get full text

Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay by Dziekan, Jerzy Michal, Yu, Han, Chen, Dan, Dai, Lingyun, Wirjanata, Grennady, Larsson, Andreas, Prabhu, Nayana, Sobota, Radoslaw Mikolaj, Bozdech, Zbynek, Nordlund, Pär

“…Subsequently, we applied MS-CETSA to quinine and mefloquine, two important antimalarial drugs with poorly characterized MoAs. …”
Get full text

Population pharmacokinetic and pharmacodynamic properties of intramuscular quinine in Tanzanian children with severe Falciparum malaria. by Hendriksen, I, Maiga, D, Lemnge, M, Mtove, G, Gesase, S, Reyburn, H, Lindegardh, N, Day, N, Von Seidlein, L, Dondorp, A, Tarning, J, White, N

“…Although artesunate is clearly superior, parenteral quinine is still used widely for the treatment of severe malaria. …”

An open randomized trial of artemether versus quinine in the treatment of cerebral malaria in African children. by Murphy, S, English, M, Waruiru, C, Mwangi, I, Amukoye, E, Crawley, J, Newton, C, Winstanley, P, Peshu, N, Marsh, K

“…We have compared the efficacy of artemether versus quinine as treatment for cerebral malaria in children in an open randomized clinical trial in Kenya. …”

Parasite viability during treatment of severe falciparum malaria: differential effects of artemether and quinine. by Murphy, S, Watkins, WM, Bray, P, Lowe, B, Winstanley, P, Peshu, N, Marsh, K

“…The effect of artemether (AR) and quinine (QN) on parasite viability ex vivo was compared in children being treated for severe Plasmodium falciparum malaria. …”

Comparison of artemisinin suppositories, intramuscular artesunate and intravenous quinine for the treatment of severe childhood malaria. by Cao, X, Bethell, D, Pham, T, Ta, T, Tran, T, Nguyen, T, Pham, T, Nguyen, T, Day, N, White, N

“…With the emergence of strains of Plasmodium falciparum resistant to both chloroquine and quinine, alternative antimalarial agents are required. …”

Alpha 1-acid glycoprotein (orosomucoid) and plasma protein binding of quinine in falciparum malaria. by Silamut, K, Molunto, P, Ho, M, Davis, T, White, N

“…Plasma concentrations of alpha 1-acid glycoprotein (AAG) and plasma protein binding of quinine were measured in 97 Thai adults with acute falciparum malaria. …”

Evidence for continued two-brood replication of Plasmodium falciparum in vivo during quinine treatment. by Davis, T, Supanaranond, W, Pukrittayakamee, S, Silamut, K, White, N

“…To investigate the relationship between fever and parasite clearance in falciparum malaria, we studied 54 adults with Plasmodium falciparum infections who were all treated with quinine. The median oral temperature profile showed peaks at 24 h intervals during the first 3 days. …”

Open comparison of intramuscular chloroquine and quinine in children with severe chloroquine-sensitive falciparum malaria. by White, N, Krishna, S, Waller, D, Craddock, C, Kwiatkowski, D, Brewster, D

“…An open paired randomised comparison of intramuscular chloroquine (3.5 mg base/kg every 6 h) and intramuscular quinine (20 mg salt/kg followed by 10 mg/kg every 12 h) was carried out in 50 Gambian children with severe falciparum malaria. 8 children died, 6 from the quinine-treated and 2 from the chloroquine-treated group. …”

Effects of Quinine on the Glycaemic Response to, and Gastric Emptying of, a Mixed-Nutrient Drink in Females and Males by Peyman Rezaie, Vida Bitarafan, Braden David Rose, Kylie Lange, Zinat Mohammadpour, Jens Frederik Rehfeld, Michael Horowitz, Christine Feinle-Bisset

“…Intraduodenal quinine, in the dose of 600 mg, stimulates glucagon-like peptide-1 (GLP-1), cholecystokinin and insulin; slows gastric emptying (GE); and lowers post-meal glucose in men. …”
Get full text

Efficacy of Quinine Sulfate in Patients with Mild-To-Moderate COVID-19: A Randomized Controlled Trial by Irma Rahayu Latarissa, Melisa Intan Barliana, Anna Meiliana, Ida Paulina Sormin, Erizal Sugiono, Cissy Bana Kartasasmita, Irmansyah Irmansyah, Keri Lestari

“…In addition, another derivate of quinine, namely Quinine Sulfate (QS), showed good in silico and in vitro antiviral activity against SARS-CoV-2. …”
Get full text

Quinine plus clindamycin vs artemether-lumefantrine for treatment of uncomplicated falciparum malaria in western Kenya by Charles O. Obonyo, Bernhards R. Ogutu

Get full text

Plasmodium falciparum malaria: rosettes are disrupted by quinine, artemisinin, mefloquine, primaquine, pyrimethamine, chloroquine and proguanil by JP Dean Goldring, Thanugarani Padayachee, Imraan Ismail

“…The combinations of pyrimethamine or primaquine, with quinine disrupted more rosettes than quinine alone. …”
Get full text

Synthesis and pharmacological evaluation of fluoro/chloro-substituted acetyl and benzoyl esters of quinine as antimalarial agents by Jean-Gonfi Mvondo Mbala, Dani Thierry Mawete, Alain Nanikafuako Makiese, Prosper Lwanzo Kwiraviwe, Bibiche Kuyubuka Pangu, Eric Buini Nguimi, Richard Cimanga Kanyanga, Luc Pieters, Gilles Degotte, Michel Frederich, Aristote Matondo, Natascha Van Pelt, Guy Caljon, Bernard Pirotte, Blaise Mbala Mavinga, Sylvie-Mireille Bambi-Nyanguile

Subjects: “…Quinine…”
Get full text

Spectroscopic Analysis of an Antimalarial Drug’s (Quinine) Influence on Human Serum Albumin Reduction and Antioxidant Potential by Wojciech Rogóż, Olga Lemańska, Jadwiga Pożycka, Aleksandra Owczarzy, Karolina Kulig, Tammam Muhammetoglu, Małgorzata Maciążek-Jurczyk

Subjects: “…quinine…”
Get full text

Efficacy of quinine, artemether-lumefantrine and dihydroartemisinin-piperaquine as rescue treatment for uncomplicated malaria in Ugandan children. by Adoke Yeka, James Tibenderana, Jane Achan, Umberto D'Alessandro, Ambrose O Talisuna

“…Though several African countries continue to use quinine as the second line treatment for patients with recurrent infections, there is little information on its efficacy when used for rescue therapy. …”
Get full text

Pemakaian Asam Askorbat Untuk Produksi Koenzim Quinine Dengan Induksi Sel Nicotiana Tabaccum by Said Nurdin, Afnizar Huzaimi

Subjects: “…asam askorbat, antioksidan, coenzim quinine, induksi sel, nicotiana tabaccum, inokulum, nutrient, callus, medium…”
Get full text