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Quinine disposition kinetics.
Published 1983“…Intravenous quinine dihydrochloride (5 mg kg-1 over 5 min) was given to seven healthy male volunteers. …”
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Quinine loading dose in cerebral malaria.
Published 1983“…In cerebral malaria, the use of currently recommended doses of intravenous quinine may result in subtherapeutic plasma concentrations during the critical first 24 hours of treatment. …”
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Towards optimal regimens of parenteral quinine for young African children with cerebral malaria: the importance of unbound quinine concentration.
Published 1993“…Young African children with severe malaria are given quinine using a regimen designed for Thai adults. …”
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Quinine idiosyncracy leading to bilateral subhyaloid haemorrhage
Published 1977-01-01Get full text
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Organocatalyst-mediated five-pot synthesis of (–)-quinine
Published 2022-12-01“…Syntheses of quinine have fascinated organic chemists for over a hundred years. …”
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Aversion to Quinine is Associated with Taste Sensation in Chicks
Published 2005-08-01Subjects: Get full text
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Binding of quinine to plasma proteins in falciparum malaria.
Published 1985“…The ratio of cerebrospinal fluid to free (unbound) plasma quinine was 0.55 +/- 0.33 which suggests that quinine does not freely cross the blood brain barrier. …”
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Disposition of oral quinine in acute falciparum malaria.
Published 1991“…Plasma quinine concentrations following oral quinine sulphate 10 mg salt/kg have been measured by HPLC in 15 adult Thai patients with uncomplicated falciparum malaria. …”
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Oral quinine pharmacokinetics and dietary salt intake.
Published 2001“…OBJECTIVES: The objective was to determine whether or not dietary salt intake affects the relative bioavailability of oral quinine. Salt intake has been shown to alter quinidine bioavailability. …”
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Transmission-blocking activities of quinine, primaquine, and artesunate.
Published 2006“…Transmission-blocking activity of quinine and primaquine was observed at relatively high concentrations (SDs): EC(50) of quinine, 642 (111) ng/ml; EC(50) of primaquine, 181 (23) ng/ml; EC(90) of quinine, 816 (96) ng/ml; EC(90) of primaquine, 543 (43) ng/ml. …”
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Antiepileptic properties of quinine: A systematic review
Published 2012“…Background: Quinine has anti-epileptic properties in animals. …”
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Quinine and severe falciparum malaria in late pregnancy.
Published 1985“…Quinine dihydrochloride was given intravenously to 12 women with severe falciparum malaria in the third trimester of pregnancy. …”
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