Advances in anticancer radiopharmaceuticals. by Jackson, MR, Falzone, N, Vallis, K

“…This review highlights recent progress in the development of anticancer radiopharmaceuticals. Molecularly targeted radiotherapy refers to the selective delivery of radionuclides that emit charged particles, such as α particles, β or Auger electrons, to cancer cells via a targeting vector. …”

Radiopharmaceuticals for imaging and therapy. by Faulkner, S, Long, N

Radiopharmaceuticals : progress and clinical perspectives / by Fritzberg, Alan R.

Subjects: “…Radiopharmaceuticals…”

Radiopharmaceuticals from generator-produced radionuclides by International Atomic Energy Agency

Subjects: “…Radiopharmaceuticals…”

Functionalized isonitrile complexes of technetium as radiopharmaceuticals by Kronauge, James Fredric

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Towards new copper based radiopharmaceuticals. by Barnard, P, Bayly, S, Betts, H, Bonnitcha, P, Christlieb, M, Dilworth, J, Holland, J, Pascu, S

Telomerase-targeting radiopharmaceuticals for the selective treatment of cancer by Bavelaar, B

“…The techniques described in this thesis may provide a building block for nucleic acid-based radiopharmaceutical research.</p>…”

Spectroelectrochemical and computational studies on the mechanism of hypoxia selectivity of copper radiopharmaceuticals. by Holland, J, Barnard, P, Collison, D, Dilworth, JR, Edge, R, Green, J, McInnes, E

“…Detailed chemical, spectroelectrochemical and computational studies have been used to investigate the mechanism of hypoxia selectivity of a range of copper radiopharmaceuticals. A revised mechanism involving a delicate balance between cellular uptake, intracellular reduction, reoxidation, protonation and ligand dissociation is proposed. …”

Analytical GC-FID method for the determination of organic solvents in radiopharmaceutical by Hassan, Hishar, Othman, Muhammad Faiz, Zakaria, Zainul Amiruddin, Ahmad Saad, Fathinul Fikri, Abdul Razak, Hairil Rashmizal

“…Background: Organic solvents play an indispensable role in most of the radiopharmaceutical production stages. It is almost impossible to remove them entirely in the final formulation of the product. …”
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The identification and validation of Auger electron-emitting radiopharmaceuticals targeting telomerase for cancer therapy by Jackson, M

In vitro kinetic studies on the mechanism of oxygen-dependent cellular uptake of copper radiopharmaceuticals. by Holland, J, Giansiracusa, J, Bell, S, Wong, L, Dilworth, JR

“…The development of hypoxia-selective radiopharmaceuticals for use as therapeutic and/or imaging agents is of vital importance for both early identification and treatment of cancer and in the design of new drugs. …”

Amplification of DNA damage by a γH2AX-targeted radiopharmaceutical by Cornelissen, B, Darbar, S, Kersemans, V, Allen, D, Falzone, N, Barbeau, J, Smart, S, Vallis, K

Amplification of DNA damage by a γH2AX-targeted radiopharmaceutical. by Cornelissen, B, Darbar, S, Kersemans, V, Allen, D, Falzone, N, Barbeau, J, Smart, S, Vallis, K

Multivariate optimisation and validation of the analytical GC-FID for evaluating organic solvents in radiopharmaceutical by Hassan, Hishar, Othman, Muhamad Faiz, Zakaria, Zainul Amiruddin, Ahmad Saad, Fathinul Fikri, Abdul Razak, Hairil Rashmizal

“…Objective: Analytical gas chromatography in line with a flame ionisation detector (GC-FID) method was developed and validated for evaluating organic solvents in radiopharmaceutical samples [18F]fluoroethyl-tyrosine ([18F]FET [18F] fluoromisonidazole ([18F]FMISO) and [18F] fluorothymidine ([18F]FLT). …”

Synthesis, X-ray crystallography, spectroelectrochemistry and computational studies on potential copper-based radiopharmaceuticals by Holland, J, Barnard, P, Collison, D, Dilworth, JR, Edge, R, Green, J, Heslop, J, McInnes, E, Salzmann, C, Thompson, A

Synthesis, X-ray crystallography, spectroelectrochemistry and computational studies on potential copper-based radiopharmaceuticals by Holland, J, Barnard, P, Collison, D, Dilworth, JR, Edge, R, Green, J, Heslop, J, McInnes, E, Salzmann, C, Thompson, A

Radioiodinated recombinant human TSH: a novel radiopharmaceutical for thyroid cancer metastases detection. by Corsetti, F, Chianelli, M, Cornelissen, B, Van de Wiele, C, D'Alessandria, C, Slegers, G, Mather, S, Di Mario, U, Filetti, S, Scopinaro, F, Signore, A

“…CONCLUSION: Results obtained so far suggest that radiolabeled rhTSH might be a promising radiopharmaceutical for diagnosis and follow-up of DTC.…”

Functionalized bis(thiosemicarbazonato) complexes of zinc and copper: synthetic platforms toward site-specific radiopharmaceuticals. by Holland, J, Aigbirhio, F, Betts, H, Bonnitcha, P, Burke, P, Christlieb, M, Churchill, G, Cowley, A, Dilworth, JR, Donnelly, P, Green, J, Peach, J, Vasudevan, SR, Warren, J

Functionalized bis(thiosemicarbazonato) complexes of zinc and copper: Synthetic platforms toward site-specific radiopharmaceuticals by Holland, J, Aigbirhio, F, Betts, H, Bonnitcha, P, Burke, P, Christlieb, M, Churchill, G, Cowley, A, Dilworth, JR, Donnelly, P, Green, J, Peach, J, Vasudevan, SR, Warren, J

Performance evaluation of Gallium-68 radiopharmaceuticals production using liquid target PETtrace 800 cyclotron by Ashhar, Zarif, Ahmad Fadzil, Muhammad Fakhrurazi, Md Safee, Zaitulhusna, Aziz, Firdaus, Ibarhim, Ummi Habibah, Nik Afinde, Nik Muhammad Fitri, Mat Ail, Noratikah, Jamal Harizan, Muhammad Ali Hazizi, Halib, Dzulieza, Alek Amran, Arieffuddin, Adawiyah, Rabiatul, Abd Hamid, Mohd Hamdi Noor, Mahamood, Mazurin, Razali, Nor Idayu, Said, Mohamad Aminudin

“…Due to increased demand, cyclotron has an expanding role in producing Gallium-68 (68Ga) radiopharmaceuticals using solid and liquid targets. Though the liquid target produces lower end-of-bombardment activity compared to the solid target, our study presents the performance of 68Ga radiopharmaceuticals production using the liquid target by evaluating the end-of-bombardment activity and the end-of-purification activity of 68GaGaCl3. …”