Blockade of Radiation-induced EGFR Nuclear Transport Enhances Radiosensitivity of Human Cervical Cancer by LI Lu, HUANG Jianming, FENG Mei, QI Yunxiang, MA Shiqi, TAN Mingyu, LANG Jinyi

“…The survival fraction (SF2) was determined by colony formation and the dose-survival curve was fitted with a singlehit multi-target model to calculate the radiosensitization ratio (SER). Results After 4 Gy irradiation, EGFR expression in the nuclear of CaSki and HeLa cells were up-regulated in a time-dependent manner. …”
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Targeted Inhibition of HK-II Reversed the Warburg Effect to Improve the Radiosensitivity of Laryngeal Carcinoma by Chen XH, Yu DL, Zhong JT, Zhou SH, Fan J, Lu ZJ

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The Mechanism of Long Non-coding RNA in Cancer Radioresistance/Radiosensitivity: A Systematic Review by Wenhan Wu, Shijian Zhang, Jia He

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Chromosomal radiosensitivity in oncological and non-oncological patients with rheumatoid arthritis and connective tissue diseases by Dinah Rzepka, Hannah Schenker, Hans Geinitz, Elisabeth Silberberger, Dorothee Kaudewitz, Barbara Schuster, Lukas Kuhlmann, Miriam Schonath, Horacio Ayala Gaona, Bernhard Aschacher, Rainer Fietkau, Georg Schett, Luitpold Distel

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Features stereotactic radiosurgical treatment large brain metastatic lesions of the brain with hypoxic radiosensitizers by Andrey Gryazov

“…Of these, the basic group (with radiosensitizers) 77 included, in the control group — 30 patients. …”
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Composition tunability of semiconductor radiosensitizers for low-dose X-ray induced photodynamic therapy by Lei Chen, Jinghui Zhang, Lihua Xu, Luchao Zhu, Jinpeng Jing, Yushuo Feng, Zongzhang Wang, Peifei Liu, Wenjing Sun, Xiangmei Liu, Yimin Li, Hongmin Chen

Subjects: “…Radiosensitizers…”
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Chitosan-Based Glycolipid Conjugated siRNA Delivery System for Improving Radiosensitivity of Laryngocarcinoma by Jing Miao, Liwen Zhang, Peng Gao, Huawei Zhao, Xianji Xie, Junyan Wang

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Combining Gold Nanoparticles with Other Radiosensitizing Agents for Unlocking the Full Potential of Cancer Radiotherapy by Abdulaziz Alhussan, Ece Pinar Demirci Bozdoğan, Devika B. Chithrani

“…Therefore, a combined use of local radiosensitizing agents, such as GNPs, with currently available radiosensitizing drugs could make a significant impact in future RT. …”
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Targeting the DNA Damage Response and DNA Repair Pathways to Enhance Radiosensitivity in Colorectal Cancer by Siyao Deng, Tijana Vlatkovic, Moying Li, Tianzuo Zhan, Marlon R. Veldwijk, Carsten Herskind

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Specific Targeting of Antiapoptotic Bcl-2 Proteins as a Radiosensitizing Approach in Solid Tumors by Benjamin Sobol, Osama Azzam Nieto, Emily Lara Eberlein, Anna-Lena Scherr, Lars Ismail, Annika Kessler, Luisa Nader, Maximilian Schwab, Paula Hoffmeister, Nathalie Schmitt, Dirk Jäger, Stefan Welte, Katharina Seidensaal, Petros Christopoulos, Christoph Heilig, Katharina Kriegsmann, Stefan Fröhling, Mark Kriegsmann, Jochen Hess, Bruno Christian Köhler

“…This study evaluates the effects of highly specific inhibitors for Bcl-x_L (WEHI-539), Bcl-2 (ABT-199) and Mcl-1 (S63845) as radiosensitizers. Covering a broad spectrum of solid tumors, Non-Small-Cell Lung Cancer (NSCLC), Head and Neck Squamous Cell Carcinoma (HNSCC) and synovial sarcoma cell lines were exposed to fractionated radiation as standard therapy with or without Bcl-2 protein inhibition. …”
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Evaluation of the radiosensitizing potency of bromelain for radiation therapy of 4T1 breast cancer cells by Farzaneh Raeisi, Daryoush Shahbazi-Gahrouei, Elham Raeisi, Esfandiar Heidarian

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Adenoviral transduction of human acid sphingomyelinase into neo-angiogenic endothelium radiosensitizes tumor cure. by Branka Stancevic, Nira Varda-Bloom, Jin Cheng, John D Fuller, Jimmy A Rotolo, Mónica García-Barros, Regina Feldman, Shyam Rao, Ralph R Weichselbaum, Dror Harats, Adriana Haimovitz-Friedman, Zvi Fuks, Michel Sadelain, Richard Kolesnick

“…These studies define a new mechanism-based approach to radiosensitize tumor cure by single dose radiotherapy (SDRT). …”
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Extracellular matrix stiffness mediates radiosensitivity in a 3D nasopharyngeal carcinoma model by Yanhua Fang, Shanshan Liang, Jianong Gao, Zhe Wang, Cheng Li, Ruoyu Wang, Weiting Yu

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Targeting Cullin-RING E3 Ligases for Radiosensitization: From NEDDylation Inhibition to PROTACs by Shuhua Zheng, Wensi Tao

“…In this review article, we will summarize the most important research findings of targeting CRLs for radiosensitization.…”
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Research Progress on Anti-tumor and Radiosensitization of Polyphenols Based on Non-coding RNA Regulation by LI Xue, LI Li, WANG Xiaolong, HAO Limin, LIU Yongqi, LIU Keke, ZHANG Xuemei, LU Jike, YI Juanjuan

Subjects: “…polyphenols; ionizing radiation; non-coding rna; anti-tumor; radiosensitization…”
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Effect and Mechanism of Radiosensitization of Poly (ADP-Ribose) Polymerase 
Inhibitor on Lewis Cells and Xenografts by Wei WANG, Bixia DUAN, Li ZENG

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Changes in Radiosensitivity to Gamma-Rays of Lymphocytes from Hyperthyroid Patients Treated with I-131 by Valentina Dini, Massimo Salvatori, Mauro Belli, Maria Elena Lago, Alessandra Nosdeo, Donatella Pia Dambra, Luisa Lo Conte, Ilaria Pecchia, Alessandro Giordano

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Standard sub-thermoneutral caging temperature influences radiosensitivity of hematopoietic stem and progenitor cells. by Benjamin J Povinelli, Kathleen M Kokolus, Jason W-L Eng, Christopher W Dougher, Leslie Curtin, Maegan L Capitano, Christi T Sailsbury-Ruf, Elizabeth A Repasky, Michael J Nemeth

“…Alleviation of this cold-stress by housing mice at a thermoneutral temperature (30°C) resulted in significantly greater baseline radiosensitivity to a lethal dose of TBI with more HSPCs from mice housed at thermoneutral temperature undergoing apoptosis following non-lethal TBI. …”
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SPINK1 as a plasma marker for tumor hypoxia and a therapeutic target for radiosensitization by Tatsuya Suwa, Minoru Kobayashi, Yukari Shirai, Jin-Min Nam, Yoshiaki Tabuchi, Norihiko Takeda, Shusuke Akamatsu, Osamu Ogawa, Takashi Mizowaki, Ester M. Hammond, Hiroshi Harada

“…An anti-SPINK1 neutralizing antibody exhibited a radiosensitizing effect. These results suggest that SPINK1 secreted from hypoxic cells protects the surrounding and relatively oxygenated cancer cells from radiation in a paracrine manner, justifying the use of SPINK1 as a target for radiosensitization and a plasma marker for predicting tumor hypoxia.…”
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Usher Syndrome Belongs to the Genetic Diseases Associated with Radiosensitivity: Influence of the ATM Protein Kinase by Joëlle Al-Choboq, Mélanie L. Ferlazzo, Laurène Sonzogni, Adeline Granzotto, Laura El-Nachef, Mira Maalouf, Elise Berthel, Nicolas Foray

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