Showing 381 - 400 results of 1,522 for search '"radiosensitivity"', query time: 0.09s Refine Results
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    Effection and Mechanism of Radiosensitivity of Non-small Cell Lung Cancer Cell Line H358 Following Gefitinib Treatment by Jie DENG, Liang ZHUANG, Yuan CHEN

    Published 2011-11-01
    “…The aims of the present study are to observe whether gefitinib, a selective EGFR tyrosine kinase inhibitor, can radiosensitize the NSCLC H358 cell line and to investigate the mechanism by which this drug restores the radiosensitivity of NSCLC cells. …”
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    Article
  3. 383

    Knockdown long non-coding RNA HCP5 enhances the radiosensitivity of esophageal carcinoma by modulating AKT signaling activation by Yue Guo, Lan Wang, Hui Yang, Nannan Ding

    Published 2022-01-01
    “…The related functional experiments were used to investigate whether the radiosensitivity of esophageal squamous cell carcinoma was affected by the inhibition of HCP5. …”
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    CYLD induces high oxidative stress and DNA damage through class I HDACs to promote radiosensitivity in nasopharyngeal carcinoma by Yueshuo Li, Chenxing Yang, Longlong Xie, Feng Shi, Min Tang, Xiangjian Luo, Na Liu, Xudong Hu, Yongwei Zhu, Ann M. Bode, Qiang Gao, Jian Zhou, Jia Fan, Xuejun Li, Ya Cao

    Published 2024-01-01
    “…Our findings offer novel insight into the function of CYLD in tumor and uncover important roles for CYLD-HDAC axis in radiosensitivity, which provide new molecular target and therapeutic strategy for tumor radiotherapy.…”
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    A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown. by Higgins, G, Prevo, R, Lee, Y, Helleday, T, Muschel, R, Taylor, S, Yoshimura, M, Hickson, I, Bernhard, E, Mckenna, W

    Published 2010
    “…However, many of the key therapeutically exploitable mechanisms that determine intrinsic tumor radiosensitivity are largely unknown. We have conducted a small interfering RNA (siRNA) screen of 200 genes involved in DNA damage repair aimed at identifying genes whose knockdown increased tumor radiosensitivity. …”
    Journal article
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