Knockdown of LINC00511 enhances radiosensitivity of lung adenocarcinoma via regulating miR-497-5p/SMAD3 by Chongxin Li, Yanyan Fu, Yongmei He, Nan Huang, Jun Yue, Yi Miao, Jialing Lv, Youchuan Xiao, Ruoyu Deng, Chao Zhang, Meifang Huang

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Retraction: Enhancing radiosensitivity of melanoma cells through very high dose rate pulses released by a plasma focus device

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Gold nanoparticles enhances radiosensitivity in glioma cells by inhibiting TRAF6/NF-κB induced CCL2 expression by Hao Wang, Qian Xu, Xianning Dong, Zhiling Guan, Ziyu Wang, Yuanyuan Hao, Ruichun Lu, Ling Chen

“…However, combining radiotherapy with a radiosensitizer could be an effective strategy to mitigate the radioresistance of glioma cells. …”
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Synthesis and characterization of actively HER-2 Targeted Fe3O4@Au nanoparticles for molecular radiosensitization of breast cancer by Behnaz Babaye Abdollahi, Marjan Ghorbani, Hamed Hamishehkar, Reza Malekzadeh, Alireza Farajollahi

“…Introduction: The present study was done to assess the effect of molecularly-targeted core/shell of iron oxide/gold nanoparticles (Fe3O4@AuNPs) on tumor radiosensitization of SKBr-3 breast cancer cells. Methods: Human epidermal growth factor receptor-2 (HER-2)-targeted Fe3O4@AuNPs were synthesized by conjugating trastuzumab (TZ, Herceptin) to PEGylated (PEG)-Fe3O4@AuNPs (41.5 nm). …”
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Targeting FBXO22 enhances radiosensitivity in non-small cell lung cancer by inhibiting the FOXM1/Rad51 axis by Yunshang Chen, Yun Zhou, Xue Feng, Zilong Wu, Yongqiang Yang, Xinrui Rao, Rui Zhou, Rui Meng, Xiaorong Dong, Shuangbing Xu, Sheng Zhang, Gang Wu, Xiaohua Jie

“…Furthermore, we found that deguelin, a potential inhibitor of FBXO22, enhanced radiosensitivity in an FBXO22/Rad51-dependent manner and was safely tolerated in vivo. …”
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Microwave hyperthermia enhances radiosensitization by decreasing DNA repair efficiency and inducing oxidative stress in PC3 prostatic adenocarcinoma cells by Yajun Wu, Pengyuan Liu, Wendy Chen, Shiting Bai, Sisi Chen, Jianglin Chen, Xiaogang Xu, Jindan Xia, Yufei Wu, Jianjun Lai, Chuan Sun, Zhenghong Lao, Xiaoqing Wan, Zhibing Wu

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Ex vivo γH2AX assay for tumor radiosensitivity in primary prostate cancer patients and correlation with clinical parameters by Ioana M. Marinescu, Manuel Rogg, Simon Spohn, Moritz von Büren, Marius Kamps, Cordula A. Jilg, Elena Fountzila, Kyriaki Papadopoulou, Lara Ceci, Alisa Bettermann, Juri Ruf, Matthias Benndorf, Sonja Adebahr, Daniel Zips, Anca L. Grosu, Christoph Schell, Constantinos Zamboglou

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Black Phosphorus Quantum Dots Enhance the Radiosensitivity of Human Renal Cell Carcinoma Cells through Inhibition of DNA-PKcs Kinase by Yue Lang, Xin Tian, Hai-Yue Dong, Xiang-Xiang Zhang, Lan Yu, Ming Li, Meng-Meng Gu, Dexuan Gao, Zeng-Fu Shang

“…These findings demonstrate that BPQDs have potential applications in radiosensitizing RCC cells.…”
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Hypoxia Modulates Radiosensitivity and Response to Different Radiation Qualities in A549 Non-Small Cell Lung Cancer (NSCLC) Cells by Hasan Nisar, Frederik M. Labonté, Marie Denise Roggan, Claudia Schmitz, François Chevalier, Bikash Konda, Sebastian Diegeler, Christa Baumstark-Khan, Christine E. Hellweg

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Long-Term Cultured Human Glioblastoma Multiforme Cells Demonstrate Increased Radiosensitivity and Senescence-Associated Secretory Phenotype in Response to Irradiation by Lina Alhaddad, Zain Nofal, Margarita Pustovalova, Andreyan N. Osipov, Sergey Leonov

“…In contrast, the irradiated long-term cultured U87H cells possessed dose-related increases in the proportion of multinucleated giant cancer cells (MGCCs), while demonstrating higher radiosensitivity (lower self-renewal) and a significantly reduced fraction of DNA-replicating cells compared to short-term cultured U87L cells. …”
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PI3K/mTOR Dual Inhibitor PF-04691502 Is a Schedule-Dependent Radiosensitizer for Gastroenteropancreatic Neuroendocrine Tumors by Zeta Chow, Jeremy Johnson, Aman Chauhan, Tadahide Izumi, Michael Cavnar, Heidi Weiss, Courtney M. Townsend, Lowell Anthony, Carrigan Wasilchenko, Matthew L. Melton, Jörg Schrader, B. Mark Evers, Piotr Rychahou

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Killing two birds with one stone: Blocking the mitochondrial pyruvate carrier to inhibit lactate uptake by cancer cells and radiosensitize tumors by Catherine Vander Linden, Cyril Corbet

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The Expression of Connexin 26 Regulates the Radiosensitivity of Hepatocellular Carcinoma Cells through a Mitogen-Activated Protein Kinases Signal Pathway by Yuan Li, Li Yang, Rui Tao, Yajing Shang, Minqiong Sun, Shichao Peng, Guoping Zhao, Ye Zhao

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Impact of AKT1 on cell invasion and radiosensitivity in a triple negative breast cancer cell line developing brain metastasis by Joanna Kempska, Leticia Oliveira-Ferrer, Astrid Grottke, Minyue Qi, Malik Alawi, Felix Meyer, Kerstin Borgmann, Fabienne Hamester, Kathrin Eylmann, Maila Rossberg, Daniel J. Smit, Manfred Jücker, Elena Laakmann, Isabell Witzel, Barbara Schmalfeldt, Volkmar Müller, Karen Legler

“…The effect of AKT1-knockout on radiosensitivity of MDA-MB-231BR cell lines was determined via colony formation assays after cell irradiation. …”
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PTEN Loss Enhances Error-Prone DSB Processing and Tumor Cell Radiosensitivity by Suppressing RAD51 Expression and Homologous Recombination by Xile Pei, Emil Mladenov, Aashish Soni, Fanghua Li, Martin Stuschke, George Iliakis

“…Notably, PTEN deficiency radiosensitizes cells to PARP inhibitors, Olaparib and BMN673. …”
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Targeting PI3K/AKT/mTOR Signaling Pathway as a Radiosensitization in Head and Neck Squamous Cell Carcinomas by Yu-Chieh Su, Wei-Chang Lee, Chih-Chun Wang, Shyh-An Yeh, Wen-Hui Chen, Po-Jen Chen

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Radiation-Induced Changes of microRNA Expression Profiles in Radiosensitive and Radioresistant Leukemia Cell Lines with Different Levels of Chromosome Abnormalities by Daria Liamina, Wladimir Sibirnyj, Anna Khokhlova, Viacheslav Saenko, Eugenia Rastorgueva, Aleksandr Fomin, Yury Saenko

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Effect of Gold Nanoparticles Conjugated with Folic Acid on the Absorption and Radiosensitization of Cervical Cancer Cells Under 6 MV Photon Irradiation by Bahare Amini Kadijani, Bijan Hashemi, Seied Rabi Mahdavi, Masoud Soleimani

“…Incubation of the cells with this concentration was performed for 2, 4, and 24 hours and it was observed that in 4 hours, the absorption rate of targeted GNPs was about 4 times higher than that of non-targeted GNPs. The radiosensitization ratios of targeted and non-targeted GNPs in the studied cancer cells relative to the control group (without NPs) exposed to 6 MV photon radiation were 1.32±0.02 and 1.19±0.02, respectively. …”
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YY1 modulates the radiosensitivity of esophageal squamous cell carcinoma through KIF3B-mediated Hippo signaling pathway by Chunyan Zheng, Zhe Li, Chuanxi Zhao, Xiaoyang Yin, Lei Feng, Zhongtang Wang, Chengxin Liu, Baosheng Li

“…YY1 depletion enhanced the radiosensitivity of ESCC in vitro and in vivo. Multi-group sequencing showed that downregulation of YY1 inhibited the transcriptional activity of Kinesin Family Member 3B (KIF3B), which further activated the Hippo signaling pathway by interacting with Integrin-beta1 (ITGB1). …”
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MicroRNA-381 Enhances Radiosensitivity in Esophageal Squamous Cell Carcinoma by Targeting X-Linked Inhibitor of Apoptosis Protein [Retraction] by Zhou S, Cui Y, Yu D, Liang J, Zhang M, Ye W

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