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Therapeutic Potential of (−)-Agelamide D, a Diterpene Alkaloid from the Marine Sponge <i>Agelas</i> sp., as a Natural Radiosensitizer in Hepatocellular Carcinoma Models
Published 2020-09-01“…Previously, we reported that extracts of the marine sponge <i>Agelas</i> sp. may contain a natural radiosensitizer for HCC treatment. In this study, we isolated (−)-agelamide D from <i>Agelas</i> extract and investigated the mechanism underlying its radiosensitization. (−)-Agelamide D enhanced radiation sensitivity of Hep3B cells with decreased clonogenic survival and increased apoptotic cell death. …”
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523
Evaluation of Sinensetin Derived From Flavonoids-Rich Orthosiphon Stamineus as a New Radiosensitizer in MDA-MB-231 and T47D as Breast Cancer Cell Lines
Published 2023-03-01“…More ever, expression level of, Bcl-2, STAT3, and increased P53 via treated cells with Sinensetin (SIN) and X-ray.Conclusion: Due to the results, Sinensetin (SIN) can be mentioned as a novel radiosensitizer and its effects may considered increasing apoptosis following DNA damage induced by irradiation.…”
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5-(<i>N</i>-Trifluoromethylcarboxy)aminouracil as a Potential DNA Radiosensitizer and Its Radiochemical Conversion into <i>N</i>-Uracil-5-yloxamic Acid
Published 2020-09-01Subjects: “…radiosensitizer…”
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526
OncomiR miR-182-5p Enhances Radiosensitivity by Inhibiting the Radiation-Induced Antioxidant Effect through SESN2 in Head and Neck Cancer
Published 2021-11-01“…Overexpression of miR-182-5p enhanced the radiosensitivity of HNSCC cells by increasing intracellular reactive oxygen species (ROS) levels, suggesting that expression of the miR-182 family is beneficial for radiotherapy. …”
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527
MicroRNA‐372 enhances radiosensitivity while inhibiting cell invasion and metastasis in nasopharyngeal carcinoma through activating the PBK‐dependent p53 signaling pathway
Published 2019-02-01“…In conclusion, the study shows that up‐regulated miR‐372 promotes radiosensitivity by activating the p53 signaling pathway via inhibition of PBK.…”
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The PI3K/mTOR dual inhibitor BEZ235 nanoparticles improve radiosensitization of hepatoma cells through apoptosis and regulation DNA repair pathway
Published 2020-03-01Subjects: Get full text
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A three-in-one-bullet for oesophageal cancer: replication fork collapse, spindle attachment failure and enhanced radiosensitivity generated by a ruthenium(II) metallo-intercalator
Published 2017“…In addition to these single-agent effects, [Ru(phen) 2 (tpphz)] 2+ functions as a radiosensitizer with efficiency comparable to cisplatin, which occurs through a synergistic enhancement of DNA damage. …”
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532
An Alternative Pipeline for Glioblastoma Therapeutics: A Systematic Review of Drug Repurposing in Glioblastoma
Published 2021-04-01Subjects: Get full text
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533
Hypoxic Radioresistance: Can ROS Be the Key to Overcome It?
Published 2019-01-01Subjects: Get full text
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534
Optimization of Size of Nanosensitizers for Antitumor Radiotherapy Using Mathematical Modeling
Published 2023-07-01Subjects: Get full text
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535
EGFR-antagonistic affibody-functionalized Pt-based nanozyme for enhanced tumor radiotherapy
Published 2023-06-01Subjects: Get full text
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536
Complete ablation of tumors using synchronous chemoradiation with bimetallic theranostic nanoparticles
Published 2022-01-01Subjects: Get full text
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537
Hyaluronic Acid-Functionalized Gadolinium Oxide Nanoparticles for Magnetic Resonance Imaging-Guided Radiotherapy of Tumors
Published 2020-04-01Subjects: Get full text
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538
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Curcumin Nanodiscs Improve Solubility and Serve as Radiological Protectants against Ionizing Radiation Exposures in a Cell-Cycle Dependent Manner
Published 2022-10-01Subjects: Get full text
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540
Quantifying the Effects of Combination Trastuzumab and Radiation Therapy in Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer
Published 2022-08-01Subjects: Get full text
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