Radon progeny measurements in a ventilated filter system to study respiratory-supported exposure by Franziska Papenfuß, Andreas Maier, Sonja Sternkopf, Claudia Fournier, Gerhard Kraft, Thomas Friedrich

“…The decay of progeny nuclides in the lung together with the high radiosensitivity of this tissue lead to equivalent doses implying a significant cancer risk. …”
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Stat3 inhibitor Stattic exhibits potent antitumor activity and induces chemo- and radio-sensitivity in nasopharyngeal carcinoma. by Yunbao Pan, Fuling Zhou, Ronghua Zhang, Francois X Claret

“…Taken together, Stattic inhibit Stat3 and display antitumor effect in NPC, and enhanced chemosensitivity and radiosensitivity in NPC. Therefore, our findings provide the base for more rational approaches to treat NPC in the clinic.…”
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LncRNA DUXAP8 induces breast cancer radioresistance by modulating the PI3K/AKT/mTOR pathway and the EZH2-E-cadherin/RHOB pathway by Changjiang Lei, Shaoting Li, Ying Fan, Li Hua, Qingyun Pan, Yuan Li, Zhixiong Long, Rui Yang

“…We found that the overexpression of DUXAP8 promoted radioresistance, while the knockdown of DUXAP8 expression increased radiosensitivity. Further studies revealed that DUXAP8 enhanced the radioresistance of BC cells by activating the PI3K/AKT/mTOR pathway and by repressing the expression of E-cadherin and RHOB through interaction with EZH2. …”
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Determinants of Sensitivity to Radiotherapy in Endometrial Cancer by Maria Alba Sorolla, Eva Parisi, Anabel Sorolla

“…Knowledge about the molecular determinants that confer radioresistance or radiosensitivity in endometrial cancer is still partial, as opposed to other cancers. …”
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Cytogenetic Effects in Patients after Computed Tomography Examination by Elizaveta Neronova, Sergei Aleksanin

“…The individual variations in the frequency and dicentric distribution suggested complex mechanisms of chromosome aberration induction and elimination that could be associated with individual radiosensitivity, as well as previous diagnostics that used ionizing radiation or the redistribution of small fractions of irradiated lymphocytes within the circulatory pull. …”
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Quantum Biology and the Potential Role of Entanglement and Tunneling in Non-Targeted Effects of Ionizing Radiation: A Review and Proposed Model by Bruno F. E. Matarèse, Andrej Rusin, Colin Seymour, Carmel Mothersill

“…These include NTE, low-dose hyper-radiosensitivity, hormesis, and the adaptive response. …”
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Auger electron radionuclide therapy utilising F3 peptide to target the nucleolus by Hillyar, C

“…In conclusion, ¹¹¹In-DTPA-F3 is a promising Auger electron-emitting radiotherapeutic agent that targets the nucleolus, the radiosensitivity of which may vary depending on the malignant cell line.…”

The IGF receptor as anticancer treatment target. by Macaulay, V

“…We showed that antisense-IGF-1R expression in melanoma cells leads to enhanced radiosensitivity and impaired activation of ATM, required for DNA double-strand break repair. …”

Fractionation effects in particle radiotherapy: implications for hypo-fractionation regimes. by Carabe-Fernandez, A, Dale, R, Hopewell, J, Jones, B, Paganetti, H

“…The parameter RBE(min) is introduced into the LQ formulation to account for possible changes in the β radiosensitivity coefficient with changing LET. The model is used to fit fractionated data under two conditions, where RBE(min) = 1 and RBE(min) ≠ 1. …”

miR-191 promotes radiation resistance of prostate cancer through interaction with RXRA by Ray, J, Haughey, C, Hoey, C, Jeon, J, Murphy, R, Dura-Perez, L, McCabe, N, Downes, M, Jain, S, Boutros, P, Mills, I, Liu, S

“…Furthermore, treatment of prostate cancer cells with the RXRA agonist 9-cis-retinoic acid restored radiosensitivity. Supporting this relationship, patients with high miR-191 and low RXRA abundance experienced quicker biochemical recurrence. …”

Radiation chemistry comes before radiation biology. by O'Neill, P, Wardman, P

“…First, its emphasis on quantification and characterization at the molecular level helps provide links between DNA damage, biochemical repair processes, and mutagenicity and radiosensitivity. Second, its central pillar of chemical kinetics aids understanding of the roles of 'reactive oxygen species' in cell signalling and diverse biological effects more generally, and application of radiation chemistry in the development of drugs to enhance radiotherapy and as hypoxia-specific cytotoxins or diagnostic agents. …”

Pancreatic cancer cell radiation survival and prenyltransferase inhibition: the role of K-Ras. by Brunner, T, Cengel, K, Hahn, S, Wu, J, Fraker, D, Mckenna, W, Bernhard, E

“…Inhibition of farnesyltransferase alone was sufficient to radiosensitize most K-ras mutant tumors, although K-Ras prenylation was not blocked. …”

A stochastic model for tumor control probability that accounts for repair from sublethal damage by Ponce Bobadilla, A, Maini, P, Byrne, H

“…We apply our model to prostate cancer, and find that the radiosensitivity parameters and the probability of sublethal damage during radiation are the parameters to which the TCP predictions are most sensitive. …”

The role of isoform switching and neoantigen formation in the response to radiation by Abdulghani, M

“…Loss of SRSF1 expression, which is a common response to IR across various cell types, enhances radiosensitivity in cell lines and in cancer patients.</p> <p>Moreover, the thesis explores the combined effect of SRSF1 knockdown and IR on triple-negative breast cancer cells, revealing an altered antigenic landscape with 86 putative neoantigens, and therefore offering insights into novel targeted immunotherapies. …”

Octreotide acetate enhanced radio sensitivity and induced apoptosis in MCF7 breast cancer cell line by Salih Mahmoud, Alkhansa, Abu Bakar @ Zakaria, Md Zuki, Hamzah, Hazilawati, Tengku Ahmad, Tengku Ahbrizal Farizal, Mohd Noor, Mohd Hezmee

“…However, radio resistance developed by tumour cells is the main problem in radiotherapy. As such, radiosensitization agents are used to improve radiotherapy efficiency. …”

CD98 expression can be a predictive factor of resistance to radiotherapy in head and neck squamous cell carcinoma by Hitomi Suzuki, Yohei Kawasaki, Shinsuke Suzuki, Takechiyo Yamada, Ayumi Ito, Maya Suzuki, Masahito Miura, Haruka Hatakeyama, Yasufumi Omori

“…CD98 is a marker of cancer stem cells, and it regulates radiosensitivity in head and neck squamous cell carcinoma (HNSCC). …”
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Changing Radiotherapy Paradigms in Penile Cancer by Peter A.S. Johnstone, Philippe E. Spiess, Geoff Sedor, G. Daniel Grass, Kosj Yamoah, Jacob G. Scott, Javier F. Torres-Roca

“…A genomic signature has recently been described that assays radiosensitivity of tumors and informs radiotherapy doses in these cases. …”
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Anlotinib enhances the antitumor immunity of radiotherapy by activating cGAS/STING in non-small cell lung cancer by Dong Han, Jiajia Zhang, Yawei Bao, Lei Liu, Ping Wang, Dong Qian

“…Here, we find anlotinib enhances radiosensitivity, and further increases radiotherapy-stimulated CD8+ T cell infiltration and activation via triggering cGAS/STING pathway. …”
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Calculation the Received dose by gonads arising from some common diagnostic radiography by Hassan Zarghani, Mohammad Taghi Bahreyni Toossi

“…Conclusion: One of the ways for patient and gonadal dose reduction is to use appropriate shields for radiosensitive organs such as gonads. Hence its recommended to use appropriate shields for gonads because of their high radiosensitivity.…”
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Recent Applications of Titanium Dioxide Nanoparticles as Cancer Theranostic Agents by Masoud Rezaei, Karim Khoshgard, Sara Mohammadi

“…Finally, according to the studies that have been conducted on controlling and optimizing the factors involved in the TiO2 NP radiosensitization, the mechanism of TiO2 NPs in producing the radiosensitivity effect has been discussed.…”
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