Evaluation of Radiosensitization and Cytokine Modulation by Differentially PEGylated Gold Nanoparticles in Glioblastoma Cells by Bríanna N. Kerr, Daniel Duffy, Caitríona E. McInerney, Ashton Hutchinson, Inaya Dabaja, Rana Bazzi, Stéphane Roux, Kevin M. Prise, Karl T. Butterworth

“…This study aimed to characterise both the radiosensitizing and immunomodulatory properties of differentially PEGylated GNPs in GBM cells in vitro. …”
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The Influence of MicroRNA-31 on Oxidative Stress and Radiosensitivity in Pancreatic Ductal Adenocarcinoma by Jason McGrath, Laura E. Kane, Stephen G. Maher

“…It was found that the manipulation of miR-31 altered the radiosensitivity in PDAC cells by regulating oxidative stress. …”
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In Vitro Evaluation of Rigosertib Antitumoral and Radiosensitizing Effects against Human Cholangiocarcinoma Cells by Alessio Malacrida, Roberta Rigolio, Luigi Celio, Silvia Damian, Guido Cavaletti, Vincenzo Mazzaferro, Mariarosaria Miloso

“…Lastly, Rigosertib shows to be a stronger radiosensitizer than Gemcitabine and 5-Fluorouracil. In conclusion, Rigosertib could be a potential therapeutic option, alone or in combination with radiations, for nonresectable patients with cholangiocarcinoma.…”
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Photodynamic Therapy as a Potent Radiosensitizer in Head and Neck Squamous Cell Carcinoma by Won Jin Cho, David Kessel, Joseph Rakowski, Brian Loughery, Abdo J. Najy, Tri Pham, Seongho Kim, Yong Tae Kwon, Ikuko Kato, Harold E. Kim, Hyeong-Reh C. Kim

“…This work proposes that ER/mitochondria-targeted PDT can serve as a radiosensitizer in intrinsically radioresistant HNSCC that exhibits an increased autophagic flux.…”
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Integrating Radiosensitivity Gene Signature Improves Glioma Outcome and Radiotherapy Response Prediction by Shan Wu, Jing Xu, Guang Li, Xi Jin

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Myoglobin-loaded gadolinium nanotexaphyrins for oxygen synergy and imaging-guided radiosensitization therapy by Xiaotu Ma, Xiaolong Liang, Meinan Yao, Yu Gao, Qi Luo, Xiaoda Li, Yue Yu, Yining Sun, Miffy H. Y. Cheng, Juan Chen, Gang Zheng, Jiyun Shi, Fan Wang

“…Abstract Gadolinium (Gd3+)-coordinated texaphyrin (Gd-Tex) is a promising radiosensitizer that entered clinical trials, but temporarily fails largely due to insufficient radiosensitization efficacy. …”
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A Comparative Assessment of Mechanisms and Effectiveness of Radiosensitization by Titanium Peroxide and Gold Nanoparticles by Mennaallah Hassan, Masao Nakayama, Mohammed Salah, Hiroaki Akasaka, Hikaru Kubota, Makiko Nakahana, Tatsuichiro Tagawa, Kenta Morita, Ai Nakaoka, Takeaki Ishihara, Daisuke Miyawaki, Kenji Yoshida, Yuya Nishimura, Chiaki Ogino, Ryohei Sasaki

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Prediction of radiosensitivity and radiocurability using a novel supervised artificial neural network by Zihang Zeng, Maoling Luo, Yangyi Li, Jiali Li, Zhengrong Huang, Yuxin Zeng, Yu Yuan, Mengqin Wang, Yuying Liu, Yan Gong, Conghua Xie

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Costunolide causes mitotic arrest and enhances radiosensitivity in human hepatocellular carcinoma cells by Chen Chih-Jen, Chen Ih-Sheng, Chang Hsun-Shuo, Liu Chia-Yuan, Hsu Ming-Ling, Fu Shu-Ling, Chen Yu-Jen

“…<p>Abstract</p> <p>Purpose</p> <p>This work aimed to investigate the effect of costunolide, a sesquiterpene lactone isolated from <it>Michelia compressa</it>, on cell cycle distribution and radiosensitivity of human hepatocellular carcinoma (HCC) cells.…”
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Radiosensitizing Effect of Dextran-Coated Iron Oxide Nanoparticles on Malignant Glioma Cells by Nhan Hau Tran, Vyacheslav Ryzhov, Andrey Volnitskiy, Dmitry Amerkanov, Fedor Pack, Aleksander M. Golubev, Alexandr Arutyunyan, Anastasiia Spitsyna, Vladimir Burdakov, Dmitry Lebedev, Andrey L. Konevega, Tatiana Shtam, Yaroslav Marchenko

Subjects: “…radiosensitization…”
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Cancer and Radiosensitivity Syndromes: Is Impaired Nuclear ATM Kinase Activity the Primum Movens? by Laura El Nachef, Elise Berthel, Mélanie L. Ferlazzo, Eymeric Le Reun, Joelle Al-Choboq, Juliette Restier-Verlet, Adeline Granzotto, Laurène Sonzogni, Michel Bourguignon, Nicolas Foray

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Radiosensitization by Hyperthermia: The Effects of Temperature, Sequence, and Time Interval in Cervical Cell Lines by Xionge Mei, Rosemarie ten Cate, Caspar M. van Leeuwen, Hans M. Rodermond, Lidewij de Leeuw, Dionysia Dimitrakopoulou, Lukas J.A. Stalpers, Johannes Crezee, H. Petra Kok, Nicolaas A.P. Franken, Arlene L. Oei

“…Moreover, the temperature of hyperthermia and HPV-type may also be important in radiosensitization by hyperthermia. In this study we thoroughly investigated the impact of different temperatures (37&#8722;42 &#176;C), and the sequence of and time interval (0 up to 4 h) between ionizing radiation and hyperthermia on HPV16⁺: SiHa, Caski; HPV18⁺: HeLa, C4I; and HPV^&#8722;: C33A, HT3 cervical cancer cell lines. …”
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Modulation of the Tumor Microenvironment with Trastuzumab Enables Radiosensitization in HER2+ Breast Cancer by Patrick N. Song, Ameer Mansur, Yun Lu, Deborah Della Manna, Andrew Burns, Sharon Samuel, Katherine Heinzman, Suzanne E. Lapi, Eddy S. Yang, Anna G. Sorace

“…The goal of this study is to investigate anti-HER2-induced radiosensitization of the tumor microenvironment to enhance fractionated radiotherapy in models of HER2+ breast cancer. …”
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Radiosensitization of PC3 Prostate Cancer Cells by 5-Thiocyanato-2′-deoxyuridine by Magdalena Zdrowowicz, Magdalena Datta, Michał Rychłowski, Janusz Rak

Subjects: “…radiosensitizer…”
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In Vivo Efficacy Testing of Peptide Receptor Radionuclide Therapy Radiosensitization Using Olaparib by Danny Feijtel, Thom G. A. Reuvers, Christine van Tuyll-van Serooskerken, Corrina M. A. de Ridder, Debra C. Stuurman, Erik de Blois, Nicole S. Verkaik, Peter de Bruijn, Stijn L. W. Koolen, Marion de Jong, Julie Nonnekens

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Albumin-Modified Gold Nanoparticles as Novel Radiosensitizers for Enhancing Lung Cancer Radiotherapy by Chen Y, Liu S, Liao Y, Yang H, Chen Z, Hu Y, Fu S, Wu J

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Editorial: Radiotherapy for esophageal cancer: Molecular mechanism and novel targets to improve radiosensitivity by Yanqing Liu, Adam Yongxin Ye, Jordan Lu, Jiaxing Yang, Xiao Zheng, Xiaodong Li, Xiaodong Li

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Utilization of Pharmacological Ascorbate to Enhance Hydrogen Peroxide-Mediated Radiosensitivity in Cancer Therapy by Zain Mehdi, Michael S. Petronek, Jeffrey M. Stolwijk, Kranti A. Mapuskar, Amanda L. Kalen, Garry R. Buettner, Joseph J. Cullen, Douglas R. Spitz, John M. Buatti, Bryan G. Allen

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NRP1 inhibition modulates radiosensitivity of medulloblastoma by targeting cancer stem cells by Manon Douyère, Caifeng Gong, Mylène Richard, Nadia Pellegrini-Moïse, Joël Daouk, Julien Pierson, Pascal Chastagner, Cédric Boura

“…Results We show that NRP1 inhibition by MR438 radiosensitizes MB stem-like cells in vitro. In heterotopic DAOY models, MR438 improves RT efficacy as measured by tumor growth and mouse survival. …”
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In vitro study of radiosensitivity in colorectal cancer cell lines associated with Lynch syndrome by Mingzhu Sun, Jayne Moquet, Stephen Barnard, Hannah Mancey, David Burling, Rachel Baldwin-Cleland, Kevin Monahan, Andrew Latchford, David Lloyd, Simon Bouffler, Christophe Badie, Nicola A. Anyamene, Elizabeth Ainsbury, Elizabeth Ainsbury

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