Effect of Testin Gene on Radiosensitivity of Nasopharyngeal Cancer 5-8F Cells by ZHONG Zhun, FEI Yongguang

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Photosensitivity and Radiosensitivity of Indocyanine Green on Human Cell Lines MCF7 and DFW by A Sazegarniya, S.M.H Bahreini tosi, A.R Montazer abadi, S.A Ale davood, H Esmaeili

“…To investigate chemical, optical and radiational cytotoxicity and also photosensitivity and radiosensitivity of indocyanine green, different dozes of this material were examined. …”
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Radiosensitization with Gadolinium Chelate-Coated Gold Nanoparticles Prevents Aggressiveness and Invasiveness in Glioblastoma by Durand M, Chateau A, Jubréaux J, Devy J, Paquot H, Laurent G, Bazzi R, Roux S, Richet N, Reinhard-Ruch A, Chastagner P, Pinel S

“…This work focused on the invading cancer cells after irradiation and their viability, aggressiveness, and recurrence potential were assessed using mitotic catastrophe quantification, MMP secretion analysis and neurosphere assays, respectively.Results: In vitro clonogenic assays showed that Au@DTDTPA(Gd) nanoparticles exerted a radiosensitizing effect on U87 cells, and in vivo experiments suggested a benefit of the combined treatment “RT 2× 5 Gy + Au@DTDTPA(Gd)” compared to RT alone. …”
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Targeting Glucose Metabolism of Cancer Cells with Dichloroacetate to Radiosensitize High-Grade Gliomas by Kristina M. Cook, Han Shen, Kelly J. McKelvey, Harriet E. Gee, Eric Hau

“…Several metabolic drugs have been used as a novel approach to improve the radiosensitivity of HGGs, including dichloroacetate (DCA), a small molecule used to treat children with congenital mitochondrial disorders. …”
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Neuroprotection of Radiosensitive Juvenile Mice by Ultra-High Dose Rate FLASH Irradiation by Yasaman Alaghband, Samantha N. Cheeks, Barrett D. Allen, Pierre Montay-Gruel, Ngoc-Lien Doan, Benoit Petit, Patrik Goncalves Jorge, Erich Giedzinski, Munjal M. Acharya, Marie-Catherine Vozenin, Charles L. Limoli

“…To circumvent these clinical complications, we have investigated the capability of ultra-high dose rate FLASH-radiotherapy (FLASH-RT) to protect the radiosensitive juvenile mouse brain from normal tissue toxicities. …”
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A novel role for TTK in homologous recombination: implications for breast cancer radiosensitivity by Benjamin C. Chandler, Corey Speers

“…By correlating gene expression with early locoregional recurrence, we nominate TTK protein kinase as a mediator of radioresistance. TTK inhibition radiosensitizes in vitro and in vivo through a novel mechanism of impaired homologous recombination and represents a promising translational strategy.…”
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Lamellipodin-RICTOR Signaling Mediates Glioblastoma Cell Invasion and Radiosensitivity Downstream of EGFR by Stefanie Moritz, Matthias Krause, Jessica Schlatter, Nils Cordes, Anne Vehlow

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Emulsion Technology in Nuclear Medicine: Targeted Radionuclide Therapies, Radiosensitizers, and Imaging Agents by Winuprasith T, Koirala P, McClements DJ, Khomein P

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Effects of the PARP inhibitor Niraparib on the radiosensitivity of human lung and cervical cancer cells by Yue Feng, Shiyi Pi, Yuwei Li, Yu Zhang, Hongwei Zeng, E. Xiangyu, Yang Zhang, Jingping Yu

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Iron Oxide Nanoparticles in Cancer Treatment: Cell Responses and the Potency to Improve Radiosensitivity by Maria V. Shestovskaya, Anna L. Luss, Olga A. Bezborodova, Valentin V. Makarov, Anton A. Keskinov

Subjects: “…radiosensitization…”
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The impact of radiosensitivity on clinical outcomes of spinal metastases treated with stereotactic body radiotherapy by Lanlan Guo, Qingqing Xu, Lixin Ke, Ziwei Wu, Ziyi Zeng, Lei Chen, Yuanyuan Chen, Lixia Lu

“…On the basis of radiosensitivity, patients were divided into two groups—radiosensitive and radioresistant. …”
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Estrogen receptor inhibition mediates radiosensitization of ER-positive breast cancer models by Anna R. Michmerhuizen, Lynn M. Lerner, Andrea M. Pesch, Connor Ward, Rachel Schwartz, Kari Wilder-Romans, Meilan Liu, Charles Nino, Kassidy Jungles, Ruth Azaria, Alexa Jelley, Nicole Zambrana Garcia, Alexis Harold, Amanda Zhang, Bryan Wharram, Daniel F. Hayes, James M. Rae, Lori J. Pierce, Corey W. Speers

“…These findings provide preclinical evidence that concurrent treatment with ET and RT may be an effective radiosensitization strategy.…”
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Regulation of m6A modification on ferroptosis and its potential significance in radiosensitization by Xun Chen, Lejia Zhang, Yi He, Siyuan Huang, Shangwu Chen, Wei Zhao, Dongsheng Yu

“…Dynamic m6A modification controlled by m6A regulatory factors also affects the susceptibility of cells to ferroptosis, thereby determining the radiosensitivity of tumor cells to radiotherapy. In this review, we summarize the mechanism and significance of radiotherapy induced ferroptosis, analyze the regulatory characteristics of m6A modification on ferroptosis, and discuss the possibility of radiosensitization by enhancing m6A-mediated ferroptosis. …”
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Effect of Autophagy Inhibitors on Radiosensitivity in DNA Repair-Proficient and -Deficient Glioma Cells by Tareq Saleh, Homood M. As Sobeai, Ali Alhoshani, Khalid Alhazzani, Mashal M. Almutairi, Moureq Alotaibi

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Lomeguatrib Increases the Radiosensitivity of MGMT Unmethylated Human Glioblastoma Multiforme Cell Lines by Anna Kirstein, Daniela Schilling, Stephanie E. Combs, Thomas E. Schmid

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Effective Radiosensitization of Bladder Cancer Cells by Pharmacological Inhibition of DNA-PK and ATR by Ahmed Ali Chughtai, Julia Pannhausen, Pia Dinger, Julia Wirtz, Ruth Knüchel, Nadine T. Gaisa, Michael J. Eble, Michael Rose

“…This study aims at analyzing the impact of the pharmacological inhibition of DNA damage response (DDR) targets (DNA-PK and ATR) on radiosensitization of bladder cancer cell lines of different molecular/histological subtypes. …”
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TOPK modulates tumour-specific radiosensitivity and correlates with recurrence after prostate radiotherapy by Pirovano, G, Ashton, T, Herbert, K, Bryant, R, Verrill, C, Cerundolo, L, Buffa, F, Prevo, R, Harrap, I, Ryan, A, Macaulay, V, McKenna, W, Higgins, G

“…</p><p> Results: TOPK knockdown did not alter radiation response in normal tissues, but significantly enhanced radiosensitivity in cancer cells. This result was recapitulated in TOPK knock-out cells and with the TOPK inhibitor, OTS964. …”

An analysis of the relationship between radiosensitivity and volume effects in tumor control probability modeling. by Buffa, F, Fenwick, J, Nahum, A

“…The dependence of local tumor control probability (tcp) on tumor volume is analyzed and discussed with the help of radiobiological modeling; in particular the impact of possible correlations between mean tumor radiosensitivity and tumor dimensions on the tcp volume dependence is explored. …”

OXYGEN RADIOSENSITIZATION - FACTORS INFLUENCING THE POSTRADIOLYTIC DECAY OF PEROXIDES IN IRRADIATED AQUEOUS SYSTEMS by Frew, J, Jones, P, Scholes, G

Efficacy of radiosensitizing doped titania nanoparticles under hypoxia and preparation of an embolic microparticle by Morrison, R, Rybak-Smith, M, Thompson, J, Thiebaut, B, Hill, M, Townley, H

“…The aim of this study was to develop a manufacturing protocol for large-scale production of doped titania radiosensitizing nanoparticles (NPs) to establish their activity under hypoxia and to produce a multimodal radiosensitizing embolic particle for cancer treatment. …”