Raltegravir monohydrate by H. S. Yathirajan, Brian J. Anderson, Jerry P. Jasinski, Thammarse S. Yamuna, Manpreet Kaur

Get full text

HIV resistance to raltegravir by Clavel François

“…One unique property of HIV resistance to raltegravir is that each of these different resistance pathways are mutually exclusive and appear to evolve separately on distinct viral genomes. …”
Get full text

Raltegravir use in special populations by Johnson Margaret

“…<p>Abstract</p> <p>Raltegravir, the first approved integrase inhibitor, has been shown to be virologically effective in Phase II and Phase III clinical trials in both treatment naïve and triple class resistant patients. …”
Get full text

Raltegravir in treatment naïve patients by Cossarini F, Castagna A, Lazzarin A

“…</p> <p>Raltegravir is generally well tolerated and adverse events were generally similar in raltegravir and comparator arms throughout all studies. …”
Get full text

Drug-drug interactions with raltegravir by Burger David M

“…Due to the relatively broad therapeutic range of raltegravir almost all co-administered agents can safely be combined with raltegravir, with the exception of rifampin in which a doubling of the raltegravir dose to 800 mg BD is currently recommended.…”
Get full text

Raltegravir in the management of HIV-infected patients by Hans-J&amp;uuml;rgen Stellbrink

“…Hans-J&amp;uuml;rgen StellbrinkICH and IPM Study Center Hamburg, Hamburg, GermanyAbstract: Raltegravir has recently been licensed for the treatment of HIV-1 infection. …”
Get full text

Raltegravir: first in class HIV integrase inhibitor by Zelalem Temesgen, Dawd S Siraj

“…Raltegravir is first in a novel class of antiretroviral drugs known as integrase inhibitors. …”
Get full text

Role of raltegravir in the management of HIV-1 infection by Okeke NL, Hicks C

“…This review focuses on the evidence supporting raltegravir&amp;rsquo;s efficacy in an array of clinical settings. …”
Get full text

Raltegravir: molecular basis of its mechanism of action by Mouscadet Jean-François, Tchertanov Luba

Subjects: Get full text

Raltegravir cerebrospinal fluid concentrations in HIV-1 infection. by Aylin Yilmaz, Magnus Gisslén, Serena Spudich, Evelyn Lee, Anura Jayewardene, Francesca Aweeka, Richard W Price

“…Raltegravir is an HIV-1 integrase inhibitor currently used in treatment-experienced HIV-1-infected patients resistant to other drug classes. …”
Get full text

Allergic hypersensitivity to antiretroviral drugs: etravirine, raltegravir and darunavir by Manuel Anastacio Sánchez-Olivas, Martha Patricia Valencia-Zavala, Gloria Bertha Vega-Robledo, Jesús Alberto Sánchez-Olivas, Guillermo Velázquez-Sámano

Get full text

Raltegravir Attenuates Experimental Pulmonary Fibrosis In Vitro and In Vivo by Xue Zhang, Haidi Huang, Guanghua Zhang, Defang Li, Hongbo Wang, Wanglin Jiang

Subjects: “…Raltegravir…”
Get full text

Dissolution Enhancement of Raltegravir by Hot Melt Extrusion Technique by Ahmed S. Abdul Jabbar

“…The HME raltegravir was formulated into tablet by direct compression method. …”
Get full text

Polymorphisms of HIV-2 integrase and selection of resistance to raltegravir by Goubau Patrick, Dao Sounkalo, Ternes Anne-Marie, Oumar Aboubacar, Lambert Christine, Triqueneaux Perrine, Bercoff Danielle, Schmit Jean-Claude, Ruelle Jean

“…</p> <p>To select for raltegravir (RAL)-resistant variants <it>in vitro</it>, the ROD strain was cultured under increasing sub-optimal RAL concentrations for successive rounds. …”
Get full text

Drug-induced hypersensitivity syndrome after initiation of darunavir and raltegravir by Walter de Araujo Eyer-Silva, Maria Alessandra Leite Freire, Guilherme Almeida Rosa da Silva

Get full text

Long-term efficacy and safety of raltegravir in the management of HIV infection by Liedtke MD, Tomlin CR, Lockhart SM, Miller MM, Rathbun RC

“…Serious adverse effects with raltegravir are rare but include rhabdomyolysis and severe skin and hypersensitivity reactions. …”
Get full text

Clinical utility of raltegravir for the treatment of HIV infection in children and adolescents by Nuttall J, Meyers T, Eley B

“…Increased availability of RAL and the introduction of second-generation integrase inhibitors are likely to further extend the utility of this class of ARV drugs.Keywords: antiretroviral therapy, integrase strand transfer inhibitor, raltegravir, HIV-1…”
Get full text

Rapid Reduction in HIV Viral Load in Late Pregnancy with Raltegravir by Agnes Cha PharmD, Raisa Shaikh PharmD, Shalonda Williams PharmD, Leonard L. Berkowitz MD

“…The use of raltegravir (RAL) is not preferred to prevent perinatal transmission in pregnancy due to lack of safety and pharmacokinetic data in this population. …”
Get full text

Raltegravir in combination with other antiretroviral agents for the treatment of HIV infection by Lisa M Chirch, Roy T Steigbigel

“…Resistance to raltegravir is unusual given its recent availability, but resistance with identified viral mutation pathways in the integrase gene in patients receiving the drug does occur.Keywords: raltegravir, integrase, human immunodeficiency virus, drug resistance…”
Get full text

Repurposing raltegravir for reducing inflammation and treating cancer: a bioinformatics analysis by Zahra Nikfarjam, Reza Rakhshi, Farshid Zargari, Mahdi Aalikhani, Amin Moradi Hasan-Abad, Zahra Bazi

Subjects: Get full text