Effect of measuring ambulatory blood pressure on sleep and on blood pressure during sleep. by Davies, R, Jenkins, N, Stradling, J

“…Both also caused a rise in beat to beat blood pressure. During non-rapid eye movement sleep, this rise led to the ABP machine overestimating the true systolic blood pressure during sleep by a mean of 10 (SD 14.8) mm Hg and the TM2420 by a mean of 6.3 (8.2) mm Hg. …”

Effect of SX-3228, a selective ligand for the BZ1 receptor, on sleep and waking during the light-dark cycle in the rat by F. Alvariño, J.M. Monti, H. Jantos, D. Monti

“…Administration of 0.5, 1.0 and 2.5 mg/kg SX-3228, sc, to rats 1 h after the beginning of the light phase of the light-dark cycle induced a significant reduction of rapid-eye-movement sleep (REMS) during the third recording hour. …”
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Risk variants of the α-synuclein locus and REM sleep behavior disorder in Parkinson’s disease: a genetic association study by Kari Anne Bjørnarå, Lasse Pihlstrøm, Espen Dietrichs, Mathias Toft

“…Abstract Background Parkinson’s disease is a heterogeneous disorder where genetic factors may underlie clinical variability. Rapid eye movement sleep behavior disorder (RBD) is a parasomnia strongly linked to synucleinopathies, including Parkinson’s disease. …”
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Clinical characteristics in early Parkinson's disease with excessive daytime sleepiness: A cross‐sectional and longitudinal study by Yumei Liu, Ling Xue, Jun Zhao, Kaixin Dou, Guojun Wang, Anmu Xie

“…Patients with PD with EDS and greater daytime sleepiness severity presented faster cognitive decline, high possibility for rapid eye movement sleep behavior disorder, autonomic dysfunction, depression, and anxiety from cross‐sectional and longitudinal analyses. …”
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Effect of N-Acetylcysteine on Sleep: Impacts of Sex and Time of Day by Priyanka N. Bushana, Michelle A. Schmidt, Kevin M. Chang, Trisha Vuong, Barbara A. Sorg, Jonathan P. Wisor

“…Non-rapid eye movement sleep (NREMS) is accompanied by a decrease in cerebral metabolism, which reduces the consumption of glucose as a fuel source and decreases the overall accumulation of oxidative stress in neural and peripheral tissues. …”
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Locus coeruleus activity while awake is associated with REM sleep quality in older individuals by Ekaterina Koshmanova, Alexandre Berger, Elise Beckers, Islay Campbell, Nasrin Mortazavi, Roya Sharifpour, Ilenia Paparella, Fermin Balda, Christian Berthomier, Christian Degueldre, Eric Salmon, Laurent Lamalle, Christine Bastin, Maxime Van Egroo, Christophe Phillips, Pierre Maquet, Fabienne Collette, Vincenzo Muto, Daphne Chylinski, Heidi I.L. Jacobs, Puneet Talwar, Siya Sherif, Gilles Vandewalle

“…Animal research shows that it plays important roles in the transition between sleep and wakefulness, and between slow wave sleep and rapid eye movement sleep (REMS). It is unclear, however, whether the activity of the LC predicts sleep variability in humans.METHODS We used 7-Tesla functional MRI, sleep electroencephalography (EEG), and a sleep questionnaire to test whether the LC activity during wakefulness was associated with sleep quality in 33 healthy younger (~22 years old; 28 women, 5 men) and 19 older (~61 years old; 14 women, 5 men) individuals.RESULTS We found that, in older but not in younger participants, higher LC activity, as probed during an auditory attentional task, was associated with worse subjective sleep quality and with lower power over the EEG theta band during REMS. …”
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Blue Transparent OLEDs with High Stability and Transmittance for Modulating Sleep Disorders by Hyeonwook Chae, Yongjin Park, Yehhyun Jo, Yongmin Jeon, Hyunjoo Jenny Lee, Seunghyup Yoo, Kyung Cheol Choi

“…Melanopsin is stimulated at the highest level of sleep desire, reducing non‐rapid eye movement sleep duration in mice by up to 14%. Based on these results, the proposed TrOLEDs are promising candidates for modulating sleep disorders such as insomnia and narcolepsy–cataplexy with the convenience of wearable form factors.…”
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Decreased cerebrospinal fluid orexin levels not associated with clinical sleep disturbance in Parkinson's disease: A retrospective study. by Takuya Ogawa, Yuta Kajiyama, Hideaki Ishido, Shigeru Chiba, Gajanan S Revankar, Tomohito Nakano, Seira Taniguchi, Takashi Kanbayashi, Kensuke Ikenaka, Hideki Mochizuki

“…Patients with Parkinson's disease (PD) often suffer from sleep disturbances, including excessive daytime sleepiness (EDS) and rapid eye movement sleep behavior disorder (RBD). These symptoms are also experienced by patients with narcolepsy, which is characterized by orexin neuronal loss. …”
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A bibliometric analysis of the application of imaging in sleep in neurodegenerative disease by Mengfei Li, Zhenzhen Jiang, Ru Wen, Chen Liu, Jian Wang

“…A literature evaluation found that Parkinson’s disease, insomnia, sleep quality, and rapid eye movement sleep behavior disorder were the top research trends in this field.ConclusionA growing body of research has focused on sleep disorders caused by degenerative diseases. …”
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Disruption of locus coeruleus-related functional networks in Parkinson’s disease by Junyan Sun, Jinghong Ma, Linlin Gao, Junling Wang, Dongling Zhang, Lili Chen, Jiliang Fang, Tao Feng, Tao Wu

“…We used resting-state functional MRI to investigate the alterations in functional connectivity (FC) of LC-related RSNs and the associations between RSNs changes and clinical features in idiopathic rapid eye movement sleep behavior disorder (iRBD) and PD patients with (PDRBD+) and without RBD (PDRBD−). …”
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Correlation of Sleep Disturbance and Cognitive Impairment in Patients with Parkinson’s Disease by Eun Ja Kim, Joon Hyun Baek, Dong Jin Shin, Hyeon-Mi Park, Yeong-Bae Lee, Kee-Hyung Park, Dong Hoon Shin, Young Noh, Young Hee Sung

“…The risk factors for cognitive decline in PD patients include advanced age, longer disease duration, rapid eye movement sleep behavior disorder, hallucinations, excessive daytime sleepiness, and nontremor symptoms including bradykinesia, rigidity, postural instability, and gait disturbance. …”
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Effects of using a snooze alarm on sleep inertia after morning awakening by Keiko Ogawa, Emi Kaizuma-Ueyama, Mitsuo Hayashi

“…Stage N1 sleep is non-rapid eye movement sleep that is primarily defined as a drowsy state. …”
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Should Routine Carbon Dioxide Monitoring be Performed During Polysomnography in Patients with Asthma and Chronic Obstructive Pulmonary Disease? by Gülçin Benbir Şenel, Derya Karadeniz

“…Partial carbon dioxide pressure during wakefulness, non-rapid eye movement and rapid eye movement sleep were not significantly different among the three groups. …”
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Thalamic reticular control of local sleep in mouse sensory cortex by Laura MJ Fernandez, Gil Vantomme, Alejandro Osorio-Forero, Romain Cardis, Elidie Béard, Anita Lüthi

“…We identify the thalamic reticular nucleus (TRN) as a source for local, sensory-cortex-specific non-rapid-eye-movement sleep (NREMS) in mouse. Neurons in optogenetically identified sensory TRN sectors showed stronger repetitive burst discharge compared to non-sensory TRN cells due to higher activity of the low-threshold Ca2+ channel CaV3.3. …”
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BNST GABAergic neurons modulate wakefulness over sleep and anesthesia by Mengyao Li, Wen Li, Shanshan Liang, Xiang Liao, Miaoqing Gu, Huiming Li, Xiaowei Chen, Hongliang Liu, Han Qin, Jingyu Xiao

“…Here, using in vivo fiber photometry combined with electroencephalography, electromyography, and video recordings, we found that BNST GABAergic neurons exhibited arousal-state-dependent alterations, with high activities in both wakefulness and rapid-eye movement sleep, but suppressed during anesthesia. …”
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Gut microbiota in dementia with Lewy bodies by Hiroshi Nishiwaki, Jun Ueyama, Kenichi Kashihara, Mikako Ito, Tomonari Hamaguchi, Tetsuya Maeda, Yoshio Tsuboi, Masahisa Katsuno, Masaaki Hirayama, Kinji Ohno

“…Abstract Gut microbiota and fecal bile acids were analyzed in 278 patients with α-synucleinopathies, which were comprised of 28 patients with dementia with Lewy bodies (DLB), 224 patients with Parkinson’s disease (PD), and 26 patients with idiopathic rapid eye movement sleep behavior disorder (iRBD). Similarly to PD, short-chain fatty acids-producing genera were decreased in DLB. …”
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Predicting motor, cognitive and functional impairment in Parkinson's by Lo, C, Arora, S, Baig, F, Lawton, M, El Mouden, C, Barber, T, Ruffmann, C, Klein, J, Brown, P, Ben‐Shlomo, Y, Vos, M, Hu, M

“…<strong>Objective</strong> We recently demonstrated that 998 features derived from a simple 7‐minute smartphone test could distinguish between controls, people with Parkinson's and people with idiopathic Rapid Eye Movement sleep behavior disorder, with mean sensitivity/specificity values of 84.6‐91.9%. …”

Cortical region-specific sleep homeostasis in mice: effects of time of day and waking experience by Guillaumin, M, McKillop, L, Cui, N, Fisher, S, Foster, R, de Vos, M, Peirson, S, Achermann, P, Vyazovskiy, V

“…The dynamics of EEG slow-wave activity (SWA) during sleep can be described using the two-process model, whereby the parameters of homeostatic Process S are estimated using empirical EEG SWA (0.5-4 Hz) in non-rapid eye movement sleep (NREM), and the 24-h distribution of vigilance states. …”

Effects of Positive Airway Pressure Therapy on Seizure Control in Patients with Nocturnal Epilepsy and Obstructive Sleep Apnoea Syndrome by Gülçin Benbir Şenel, Derya Karadeniz

“…Sleep efficiency (p=0.468), slowwave sleep duration (p=0.264), or rapid eye movement sleep (p=0.238) was found to be unrelated. …”
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Chaperone Hsp70 (HSPA1) Is Involved in the Molecular Mechanisms of Sleep Cycle Integration by Valentina V. Simonova, Mikhail A. Guzeev, Irina V. Ekimova, Yuri F. Pastukhov

“…This research explores (1) whether the <i>Hspa1</i> gene encoding Hsp70 protein activates during the daily rapid-eye-movement sleep (REMS) maximum, and (2) whether a lower daily deep SWS maximum affects the <i>Hspa1</i> expression level during the subsequent REMS. …”
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