Cortico-autonomic local arousals and heightened somatosensory arousability during NREMS of mice in neuropathic pain by Romain Cardis, Sandro Lecci, Laura MJ Fernandez, Alejandro Osorio-Forero, Paul Chu Sin Chung, Stephany Fulda, Isabelle Decosterd, Anita Lüthi

“…We found that the EEG spectral composition of non-rapid eye movement sleep (NREMS) in healthy mice shows an infraslow (~50 s) interval over which microarousals appear preferentially. …”
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Effect of PLA2G6 and SMPD1 Variants on the Lipid Metabolism in the Cerebrospinal Fluid of Patients with Parkinson's Disease: A Non-targeted Lipidomics Study by Yongang Li, GuiKai Ji, Mengjia Lian, Xuan Liu, Ying Xu, Yaxing Gui

“…In SMPD1, G508R variant-carrying patients with PD abundance of sphingomyelins was significantly higher and had significantly shorter rapid eye movement sleep. Conclusions Our study demonstrated that the disturbed composition and function of CSF-derived exosome lipidome during the pathological stage of PD may affect different types of sleep disorder in PD.…”
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Arousal-Inducing Effect of <i>Garcinia cambogia</i> Peel Extract in Pentobarbital-Induced Sleep Test and Electroencephalographic Analysis by Duhyeon Kim, Jinsoo Kim, Seonghui Kim, Minseok Yoon, Minyoung Um, Dongmin Kim, Sangoh Kwon, Suengmok Cho

“…Administration of GC (1500 mg/kg) significantly increased wakefulness and decreased non-rapid eye movement sleep, similar to that of caffeine (25 mg/kg), with GC and caffeine showing a significant increase in wakefulness at 2 and 6 h, respectively. …”
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The Relationship between Sleep Parameters Measured by Polysomnography and Selected Neurotrophic Factors by Marcin Sochal, Agata Binienda, Aleksandra Tarasiuk, Agata Gabryelska, Piotr Białasiewicz, Marta Ditmer, Szymon Turkiewicz, Filip Franciszek Karuga, Jakub Fichna, Adam Wysokiński

“…Electroencephalography power analysis revealed BDNF protein’s negative correlation with delta waves during rapid eye movement and non-rapid eye movement sleep. Conclusion: The study highlights associations between neurotrophins and sleep, emphasizing BDNF’s role in regulating NREM and REM sleep. …”
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Assessing impulse control behaviors in early Parkinson’s disease: a longitudinal study by Xiaobo Zhu, Jing Gan, Na Wu, Ying Wan, Lu Song, Zhenguo Liu, Yu Zhang

“…A predictive index for ICBs was generated, incorporating three baseline characteristics: anxiety, rapid eye movement sleep behavior disorder (RBD), and p-tau levels in cerebrospinal fluid (CSF).ConclusionDuring the early stages of PD, there is a notable increase in ICBs over time. …”
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A Validation Study of a Commercial Wearable Device to Automatically Detect and Estimate Sleep by Dean J. Miller, Gregory D. Roach, Michele Lastella, Aaron T. Scanlan, Clint R. Bellenger, Shona L. Halson, Charli Sargent

“…The aims of this study were to: (1) compare actigraphy (ACTICAL) and a commercially available sleep wearable (i.e., WHOOP) under two functionalities (i.e., sleep auto-detection (WHOOP-AUTO) and manual adjustment of sleep (WHOOP-MANUAL)) for two-stage categorisation of sleep (sleep or wake) against polysomnography, and; (2) compare WHOOP-AUTO and WHOOP-MANUAL for four-stage categorisation of sleep (wake, light sleep, slow wave sleep (SWS), or rapid eye movement sleep (REM)) against polysomnography. Six healthy adults (male: <i>n</i> = 3; female: <i>n</i> = 3; age: 23.0 ± 2.2 yr) participated in the nine-night protocol. …”
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Personality profile and its association with conversion to neurodegenerative disorders in idiopathic REM sleep behavior disorder by Li Zhou, Steven W. H. Chau, Yaping Liu, Jing Wang, Jihui Zhang, Ngan Yin Chan, Joey W. Y. Chan, Bei Huang, Sijing Chen, Shirley Xin Li, Vincent Chung Tong Mok, Yun Kwok Wing

“…It remained unclear whether similar personality traits could be found in idiopathic rapid eye movement sleep behavior disorder (iRBD), a prodromal stage of PD, and could predict phenoconversion to neurodegenerative disorders. …”
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Fast Sleep Stage Classification Using Cascaded Support Vector Machines with Single-Channel EEG Signals by Dezhao Li, Yangtao Ruan, Fufu Zheng, Yan Su, Qiang Lin

“…In addition, with cascaded SVM models, the classification accuracy of the non-rapid eye movement sleep stage 1 (N1) was enhanced from 41.5% to 55.65% compared with the single SVM model, and the overall classification time for each epoch was less than 1.7 s. …”
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Risk Factors in Developing Hallucinations in Parkinson’s Disease by Gülçin Benbir, Sibel Özekmekçi, Meral Çınar, Fuat Beşkardeş, Hülya Apaydın, Ethem Erginöz

“…Between these two groups, the age at onset of first PD symptom, duration of PD, Hoehn-Yahr (H&Y) staging, Unified PD Rating Scale (UPDRS) scores, duration and mean dosage of levodopa and other antiparkinsonian drugs, the presence of wearing-off phenomenon, dyskinesia and rapid eye movement sleep behaviour disorder (RBD) were evaluated. …”
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Altered sleep behavior strengthens face validity in the ArcAβ mouse model for Alzheimer’s disease by Alp Altunkaya, Cassandra Deichsel, Matthias Kreuzer, Duy-Minh Nguyen, Ann-Marie Wintergerst, Gerhard Rammes, Gerhard Schneider, Thomas Fenzl

“…EEG recordings showed decreased non-rapid eye movement sleep (NREMS) and increased wakefulness in transgenic mice (TG). …”
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Hypothalamic supramammillary neurons that project to the medial septum modulate wakefulness in mice by Mengru Liang, Tingliang Jian, Jie Tao, Xia Wang, Rui Wang, Wenjun Jin, Qianwei Chen, Jiwei Yao, Zhikai Zhao, Xinyu Yang, Jingyu Xiao, Zhiqi Yang, Xiang Liao, Xiaowei Chen, Liecheng Wang, Han Qin

“…Optogenetic stimulation of axonal terminals of SuM-MS projection induces a rapid and reliable transition to wakefulness from non-rapid-eye movement or rapid-eye movement sleep, and chemogenetic activation of SuMMS projecting neurons significantly increases wakefulness time and prolongs latency to sleep. …”
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Therapeutic Effect of Levodopa/Carbidopa/Entacapone on Sleep Disturbance in Patients with Parkinson’s Disease by Kye Won Park, Sungyang Jo, Seung Hyun Lee, Yun Su Hwang, Dagyo Lee, Ho-Sung Ryu, Sun Ju Chung

“…All patients were assessed for motor, nonmotor, and sleep-specific symptoms using the United Parkinson’s Disease Rating Scale (UPDRS), the Korean version of the Nonmotor Symptom Scale, the Parkinson’s Disease Sleep Scale (PDSS), the Epworth Sleepiness Scale, and the Rapid Eye Movement Sleep Behavior Disorder Screening Questionnaire (RBDSQ). …”
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Articulatory undershoot of vowels in isolated REM sleep behavior disorder and early Parkinson’s disease by Dominik Skrabal, Jan Rusz, Michal Novotny, Karel Sonka, Evzen Ruzicka, Petr Dusek, Tereza Tykalova

“…We aimed to assess whether vowel articulation abnormalities are present in isolated rapid eye movement sleep behaviour disorder (iRBD) and early-stage PD. …”
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Cannabinoids: Emerging sleep modulator by Zhen Xuen Brandon Low, Xin Ru Lee, Tomoko Soga, Bey Hing Goh, Deepa Alex, Yatinesh Kumari

“…Much evidence supports the role of cannabinoid receptors in the modulation of sleep, where their alteration exhibits sleep-promoting effects, including an increase in non-rapid-eye movement sleep and a reduction in sleep latency. …”
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Interactions between anterior thalamus and hippocampus during different behavioral states in the rat by Héctor Penagos. by Penagos, Héctor (Penagos Vargas, Héctor Luis)

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Basal ganglia dysfunction in idiopathic REM sleep behaviour disorder parallels that in early Parkinson’s disease by Rolinski, M, Griffanti, L, Piccini, P, Roussakis, A, Szewczyk-Krolikowski, K, Menke, R, Quinnell, T, Zaiwalla, Z, Klein, J, Mackay, C, Hu, M

“…Currently, it is unclear whether these changes are present in so-called idiopathic rapid eye movement sleep behaviour disorder (RBD), a condition associated with a high rate of future conversion to Parkinson’s. …”

Case report: Excessive daytime sleepiness as a presenting manifestation of autoimmune glial fibrillary acidic protein astrocytopathy by Mingyang Tang, Shuo Huang, Weitong Guo, Junfang Zhou, Zhencan Huang, Wanru Li, Qingqing Sun, Zan Wang

“…His Epworth Sleepiness Scale (ESS) score was 16 (reference range, &lt;10), and 24-hour polysomnography supported the diagnosis of rapid-eye-movement sleep disorder and severe sleep apnea-hypopnea syndrome. …”
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Sleep quality and architecture in COPD: the relationship with lung function abnormalities by Renata D Marques, Danilo C Berton, Nicolle J Domnik, Helen Driver, Amany F Elbehairy, Michael Fitzpatrick, Denis E O’Donnell, Simone Fagondes, José Alberto Neder

“…After controlling for age, sex, BMI, apnea-hypopnea index, nocturnal desaturation, comorbidities, and psychotropic drug prescription, FEV1/FVC was associated with sleep efficiency (β = 25.366; R2 = 14%; p < 0.001), whereas DLCO predicted sleep onset latency (β = −0.314; R2 = 13%; p < 0.001) and rapid eye movement sleep time/total sleep time in % (β = 0.085; R2 = 15%; p = 0.001). …”
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Sex differences for clinical correlates of substantia nigra neuron loss in people with Lewy body pathology by Ece Bayram, David G. Coughlin, Ravi Rajmohan, Irene Litvan

“…Sex differences for the nigral neuron loss’ association with Lewy body pathology staging and core clinical LBD features (cognitive fluctuations, visual hallucinations, rapid eye movement sleep behavior disorder, parkinsonism) during follow-up were analyzed with generalized linear models adjusting for age and Alzheimer’s pathology staging. …”
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Sensitivity of Detecting Alpha-Synuclein Accumulation in the Gastrointestinal Tract and Tissue Volume Examined by Chaewon Shin, Seong-Ik Kim, Sung-Hye Park, Jung Hwan Shin, Chan Young Lee, Han-Kwang Yang, Hyuk-Joon Lee, Seong-Ho Kong, Yun-Suhk Suh, Han-Joon Kim, Beomseok Jeon

“…Methods Nine patients with Parkinson’s disease (PD) or idiopathic rapid eye movement sleep disorder (iRBD) who underwent GI operation and had full-depth intestinal blocks were included. …”
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