Evidence of Carotid Atherosclerosis Vulnerability Regression in Real Life From Magnetic Resonance Imaging: Results of the MAGNETIC Prospective Study by Oronzo Catalano, Giulia Bendotti, Teresa L. Aloi, Alberto Ferrari Bardile, Mirella Memmi, Patrick Gambelli, Daniela Zanaboni, Alessandra Gualco, Emanuela Cattaneo, Antonio Mazza, Mauro Frascaroli, Esmeralda Eshja, Riccardo Bellazzi, Paolo Poggi, Giovanni Forni, Maria Teresa La Rovere

“…We aimed to demonstrate vulnerability regression in real life, with a comprehensive quantitative method, in patients with asymptomatic mild to moderate carotid atherosclerosis on a secondary prevention program. …”
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DNA Damage Estimation after Chronic and Combined Exposure to Endocrine Disruptors: An In Vivo Real-Life Risk Simulation Approach by Vasiliki Karzi, Eren Ozcagli, Manolis N. Tzatzarakis, Elena Vakonaki, Irene Fragkiadoulaki, Aikaterini Kalliantasi, Christina Chalkiadaki, Athanasios Alegakis, Polychronis Stivaktakis, Aikaterini Karzi, Antonios Makrigiannakis, Anca Oana Docea, Daniela Calina, Aristidis Tsatsakis

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Hematologic toxicity of radium-223 in elderly patients with metastatic Castration Resistant Prostate Cancer: a real-life experience by Renato P. Costa, Sebastiano Bordonaro, Francesco Cappuccio, Vincenzo Tripoli, Alessandra Murabito, Maria Licari, Maria R. Valerio, Paolo Tralongo

“…Materials and methods: We evaluated the hematologic toxicity of Ra-223 treatment in a real-life experience of 38 patients from two Italian cancer centers, with bone metastases from mCRPC. …”
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Incidence and Predictors of Outcome in the Treatment of In-Stent Restenosis with Drug-Eluting Balloons, a Real-Life Single-Centre Study by Kyle Murnaghan, Helen Bishop, Navjot Sandila, Bakhtiar Kidwai, Lawrence Title, Ata Ur Rehman Quraishi, Catherine Kells, Hussein Beydoun, Osama Elkhateeb

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Aflibercept Plus FOLFIRI as Second-Line Treatment for Metastatic Colorectal Cancer: A Single-Institution Real-Life Experience by Daniele Lavacchi, Giandomenico Roviello, Elisa Giommoni, Lorenzo Dreoni, Silvia Derio, Marco Brugia, Amedeo Amedei, Serena Pillozzi, Lorenzo Antonuzzo

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Effectiveness of the Use of Three-Dose Intravitreal Ziv-Aflibercept in the Management of Diabetic Macular Edema in a Real-Life Setting by Munayco-Guillén F, Vazquez-Membrillo MA, Garcia-Roa MR, De La Cruz-Vargas JA, García-Perdomo HA, Pichardo-Rodriguez R

“…The objective of this study was to evaluate in a real-life setting, the efficacy of intravitreal Ziv-aflibercept in the treatment of DME after the administration of three consecutive monthly doses.Methods: A single arm, prospective cohort study. …”
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Long-term efficacy and safety of secukinumab in real life: a 240 weeks multicenter study from Southern Italy by Stefano Dastoli, Maria Passante, Francesco Loconsole, Edoardo Mortato, Anna Balato, Vincenzo Piccolo, Claudio Guarneri, Laura Macca, Eugenio Provenzano, Giancarlo Valenti, Domenico D’Amico, Giuseppe Micali, Maria Letizia Musumeci, Giovanni Palazzo, Caterina Foti, Paolo Romita, Gabriella Fabbrocini, Matteo Megna, Ilaria Sammarra, Luigi Bennardo, Cataldo Patruno

“…Background Long-term real-life data on secukinumab use in psoriasis are limited. …”
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Risankizumab Therapy for Moderate-to-Severe Psoriasis—A Multi-Center, Long-Term, Real-Life Study from Poland by Michał Adamczyk, Joanna Bartosińska, Dorota Raczkiewicz, Kinga Adamska, Zygmunt Adamski, Maria Czubek, Beata Kręcisz, Elżbieta Kłujszo, Aleksandra Lesiak, Joanna Narbutt, Marcin Noweta, Agnieszka Owczarczyk-Saczonek, Witold Owczarek, Adam Reich, Dominik Samotij, Aleksandra Siekierko, Justyna Szczęch, Irena Walecka, Piotr Ciechanowicz, Anna Woźniacka, Agata Liszewska, Dorota Krasowska

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Knowledge, attitudes, and practices of active surveillance in prostate cancer among urologists: a real-life survey from Brazil by Marcelo Langer Wroclawski, Breno Santos Amaral, Paulo Priante Kayano, Wilson Francisco Schreiner Busato, Sebastião José Westphal, Erik Montagna, Bianca Bianco, Andrey Soares, Fernando Cotait Maluf, Gustavo Caserta Lemos, Arie Carneiro

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Acceptance of Automated Shuttles—Application and Extension of the UTAUT-2 Model to Wizard-of-Oz Automated Driving in Real-Life Traffic by Anne Rybizki, Klas Ihme, Hoai Phuong Nguyen, Linda Onnasch, Esther Bosch

“…Here, we employed the UTAUT-2 to assess acceptance of a Wizard-of-Oz automated shuttle in real-life traffic, in a study with 35 participants, before and after a first ride and after a second ride on which two incidents occurred. …”
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Chronotropic Incompetence Limits Aerobic Exercise Capacity in Patients Taking Beta-Blockers: Real-Life Observation of Consecutive Patients by Krzysztof Smarz, Maciej Tysarowski, Beata Zaborska, Ewa Pilichowska-Paszkiet, Małgorzata Sikora-Frac, Andrzej Budaj, Tomasz Jaxa-Chamiec

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Brolucizumab Intravitreal Injections for Wet Age-Related Macular Degeneration: Real-Life Study on a Cohort of Italian Patients by Carlo Gesualdo, Settimio Rossi, Clemente Maria Iodice, Francesco Guarino, Mariachiara Petrella, Fabiana Anna D’Agostino, Raffaele Perrotta, Francesca Simonelli

“…<i>Background and Objectives:</i> To report the real-life Brolucizumab therapeutical outcomes of treatment-naïve and non-treatment-naïve eyes with neovascular age-related macular degeneration (nAMD) and to analyze the incidence of therapy-related adverse events. …”
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Measurable Residual Disease in Chronic Lymphocytic Leukemia: Experience in Real-Life Setting with Dry Tube Flow Cytometric Method by Seval AKPINAR, Burhan TURGUT

“…In the patients studied with the dry tube method, the median PFS of the ones who achieved uMRD was also significantly longer than those who did not.Conclusion:Our study has indicated that flow cytometry based MRD surveillance of CLL patients in real-life setting provides prognostic information regarding PFS in accordance with clinical studies. …”
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'Real-life' benefit of hearing preservation cochlear implantation in the paediatric population: a single-site case–control study by Azita Rajai, Iain Bruce, Karolina Kluk, Mark Sladen, Jaya Nichani, Simone Schaefer, Martin Odriscoll

“…The combination of electrical hearing with either preserved acoustic hearing or amplified ‘natural’ hearing has the potential to address these issues and enable children with HPCI to closely follow normal auditory development.The aim of this study is to evaluate the ‘real-life’ benefit of preserved acoustic low-frequency hearing in children with a CI, understand the benefits of preserved natural hearing in complex listening situations and so enable parents and children to make an informed choice about implantation. …”
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Tailored therapy with turoctocog alfa pegol according to patient’s lifestyle and hemorrhagic phenotype: from clinical trial to real-life by Ilaria Nichele, Giuseppe Carli, Alberto Tosetto

“… Although the use of prophylaxis regimens with prolonged half-life factors is now widespread in the world of hemophilia A, there is a lack of real-life evidence on the impact of these products on joint health, adherence, and quality of life of patients. …”
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On behalf of the SFGM‐TC: Real‐life use of third‐party virus‐specific T‐cell transfer in immunocompromised transplanted patients by Esther Hazane Leroyer, Nadine Petitpain, Stéphane Morisset, Bénédicte Neven, Martin Castelle, Sarah Winter, Laetitia Souchet, Véronique Morel, Marie Le Cann, Mony Fahd, Karima Yacouben, Françoise Mechinaud, Marie Ouachée‐Chardin, Cécile Renard, Hélène Labussière Wallet, Marie Angoso, Charlotte Jubert, Patrice Chevallier, Alexandra Léger, Fanny Rialland, Nathalie Dhedin, Christine Robin, Sébastien Maury, Florence Beckerich, David Beauvais, Thomas Cluzeau, Michaël Loschi, Alina Fernster, Marcelo De Carvalho Bittencourt, Maxime Cravat, Karin Bilger, Laurence Clément, Véronique Decot, Mélanie Gauthier, Anne Legendre, Jérôme Larghero, Amani Ouedrani, Guillaume Martin‐Blondel, Cécile Pochon, Loïc Reppel, Hélène Rouard, Stéphanie Nguyen‐Quoc, Jean‐Hugues Dalle, Maud D'Aveni, Danièle Bensoussan

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Ranibizumab in Macular Edema Secondary to Retinal Vein Occlusion in a Real Life Practice: A Retrospective Case Series by Abdullah Ozkaya, Zeynep Alkin, Ceren Yesilkaya, Gurkan Erdogan, Irfan Perente, Muhittin Taskapili

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Real-life data on the effectiveness and safety of omalizumab in monotherapy or combined for chronic spontaneous urticaria: a retrospective cohort study by Andac Salman, Tulin Ergun, Ana Maria Gimenez-Arnau

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Risankizumab for the Treatment of the Patients with Moderate to Severe Plaque Psoriasis During a 24-Week Period: Real-Life Experience by Gönülal M, Balcı DD, Öztürkcan S

“…However, long-term studies, including more extensive patient series, are needed to validate its efficacy and safety in real-life clinical settings.Keywords: psoriasis, risankizumab, anti-IL 23…”
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Treating hidradenitis suppurativa patients with adalimumab: a real-life experience of a tertiary care center in Lisboa, Portugal by José Miguel Neves, Nélia Cunha, André Lencastre, Joana Cabete

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