Real‐life effectiveness of carfilzomib in patients with relapsed multiple myeloma receiving treatment in the context of early access: The CARMYN study by Kamel Laribi, Xavier Leleu, Nathalie Texier, Raphaël Germain, Cyrille Touzeau, Mohammad Hammoud, Alexandre Payssot, Samantha Schulmann, Ronan Le Calloch, Adrien Trebouet, Driss Chaoui, Selva David, Omar Benbrahim, Riad Benramdane, Anne Charvet‐Rumpler, Christelle Jadeau, Eglantine Rouanet, Olivier Decaux, Aurore Perrot

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Real-life impacts of olipudase alfa: The experience of patients and families taking an enzyme replacement therapy for acid sphingomyelinase deficiency by Eva M. Raebel, Samantha Wiseman, Conan Donnelly, Toni Mathieson, Jackson Pountney, Joslyn Crowe, Justin Hopkin

“…The purpose of this study is to better understand the real-life impact of ASMD on patients and caregivers and assess how olipudase alfa impacts QoL for pediatric patients and their caregivers. …”
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Impact of Remdesivir on SARS-CoV-2 Clearance in a Real-Life Setting: A Matched-Cohort Study by Spagnuolo V, Voarino M, Tonelli M, Galli L, Poli A, Bruzzesi E, Racca S, Clementi N, Oltolini C, Tresoldi M, Rovere Querini P, Dagna L, Zangrillo A, Ciceri F, Clementi M, Castagna A

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Mastectomy or Breast-Conserving Therapy for Early Breast Cancer in Real-Life Clinical Practice: Outcome Comparison of 7565 Cases by Stefanie Corradini, Daniel Reitz, Montserrat Pazos, Stephan Schönecker, Michael Braun, Nadia Harbeck, Christiane Matuschek, Edwin Bölke, Ute Ganswindt, Filippo Alongi, Maximilian Niyazi, Claus Belka

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The Rapid Phenotypic Susceptibility Testing in Real-Life Experience: How the MIC Values Impact on Sepsis Fast Diagnostic Workflow by Giuseppe Migliorisi, Maddalena Calvo, Antonina Collura, Francesca Di Bernardo, Marianna Perez, Guido Scalia, Stefania Stefani

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Assessment of patient-reported outcomes at 24 weeks of treatment with tralokinumab for atopic dermatitis: a multicentric real-life experience by Silvia Ferrucci, Francesca Barei, Simona Tavecchio, Angelo V. Marzano, Martina Zussino, Luigi Naldi, Elena Pezzolo

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Impact of the lactate dehydrogenase in association with the International Staging System prognostic score in multiple myeloma patients treated in real life by Maricy Almeida Viol Ferreira Lopes, Fabiana Higashi, Edvan de Queiroz Crusoe, Ana Lucia Miguel Peres, Priscilla Cury, Vania Tietsche de Moraes Hungria

“…Conclusion: Through the association of ISS I and normal DHL, ISS III and high DHL and others combinations, we build a new score with superior impact prognostic in our population treated in real life.…”
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Inhaled Dry Powder Antibiotics in Patients with Non-Cystic Fibrosis Bronchiectasis: Efficacy and Safety in a Real-Life Study by Miguel Ángel Martínez-García, Grace Oscullo, Esther Barreiro, Selene Cuenca, Angela Cervera, Alicia Padilla-Galo, David de la Rosa, Annie Navarro, Rosa Giron, Francisco Carbonero, Maria Castro Otero, Francisco Casas

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Clinical Aspects in Subacute Thyroiditis: A Real-Life Study on 226 Cases in Greece Amid the COVID-19 Pandemic by Nikolaos Angelopoulos, Dimitrios P. Askitis, Ioannis Androulakis, Nicolas Valvis, Rodis Paparodis, Valentina Petkova, Anastasios Boniakos, Dimitra Zianni, Ilias Perogamvros, Konstantinos Toulis, Sarantis Livadas, Ioannis Iakovou

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Safety and Effectiveness of Vedolizumab and Ustekinumab in Elderly Patients with Inflammatory Bowel Disease: A Real-Life Multicentric Cohort Study by Tom Holvoet, Marie Truyens, Cara De Galan, Harald Peeters, Francisco Mesonero Gismero, Ainara Elorza, Paola Torres, Liv Vandermeulen, Aranzazu Jauregui-Amezaga, Rocio Ferreiro-Iglesias, Yamile Zabana, Laia Peries Reverter, Jeroen Geldof, Triana Lobatón

“…The aim of the current study was to assess the safety and effectiveness of both in an elderly real-life population. Methods: A multicentric retrospective study was performed on IBD patients who started vedolizumab or ustekinumab between 2010 and 2020. …”
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A Hybrid MultiLayer Perceptron Under-Sampling with Bagging Dealing with a Real-Life Imbalanced Rice Dataset by Moussa Diallo, Shengwu Xiong, Eshete Derb Emiru, Awet Fesseha, Aminu Onimisi Abdulsalami, Mohamed Abd Elaziz

“…These classification algorithms are not always efficient when it comes to real-life datasets due to class distributions. As a result, datasets for real-life applications are generally imbalanced. …”
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Oncological Outcomes of Patients with High-Volume mCRPC: Results from a Longitudinal Real-Life Multicenter Cohort by Mariaconsiglia Ferriero, Francesco Prata, Umberto Anceschi, Serena Astore, Alfredo Maria Bove, Aldo Brassetti, Fabio Calabrò, Silvia Chiellino, Cosimo De Nunzio, Gaetano Facchini, Elisena Franzese, Michela Izzo, Riccardo Mastroianni, Leonardo Misuraca, Richard Naspro, Rocco Papalia, Annalisa Pappalardo, Giorgia Tema, Gabriele Tuderti, Beatrice Turchi, Andrea Tubaro, Giuseppe Simone

“…We reported comparable survival probabilities in a real-life series of high-volume mCRPC patients who either received upfront ARTA or chemotherapy. …”
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Differential processes of ‘Internet’ versus ‘real life’ sexual filtering and contact among men who have sex with men by Shelia R. Rice, Michael W. Ross

“…We studied the behaviors and sexual contacts in 1,000 Men who have Sex with Men (MSM), and behaviors for main and casual partners, and between Internet and In Real Life (IRL) sexual contacts for non-main partners. …”
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P1032: REAL-LIFE VALIDATION OF MIPSS70: A RETROSPECTIVE MULTICENTER AND NGS ANALYSIS FROM THE GEMFIN DATABASE by A. Hernández-Sánchez, Á. Villaverde-Ramiro, A. Álvarez-Larrán, E. Arellano-Rodrigo, M. Pérez Encinas, F. Ferrer Marín, E. Such, G. Carreño Gómez-Tarragona, N. de las Heras Rodríguez, M. A. Durán Pastor, M. I. Mata Vázquez, L. Fox, J. M. Raya Sánchez, E. Magro Mazo, M. T. Gómez Casares, M. J. Ramírez Sánchez, B. Xicoy Cirici, Á. Ramírez Páyer, M. J. Fernández Llavador, A. Á. Martín López, A. Mosquera Orgueira, J. Martínez Elicegui, M. Garrote, B. Bellosillo, T. González, J. Hernández-Rivas, J. C. Hernández Boluda

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Antibiotic treatment durations for common infectious diseases in Switzerland: comparison between real-life and local and international guideline recommendations by Cédéric Schaub, Stefanie Barnsteiner, Ladina Schönenberg, Nando Bloch, Sarah Dräger, Werner C. Albrich, Anna Conen, Michael Osthoff

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Real-Life Impact of Drug Toxicity on Dolutegravir Tolerability: Clinical Practice Data from a Multicenter Italian Cohort by Arturo Ciccullo, Gianmaria Baldin, Vanni Borghi, Filippo Lagi, Alessandra Latini, Gabriella d’Ettorre, Letizia Oreni, Paolo Fusco, Amedeo Capetti, Massimiliano Fabbiani, Andrea Giacomelli, Alessandro Grimaldi, Giordano Madeddu, Gaetana Sterrantino, Cristina Mussini, Simona Di Giambenedetto

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Cemiplimab in Ultra-Octogenarian Patients with Cutaneous Squamous Cell Carcinoma: The Real-Life Experience of a Tertiary Referral Center by Nerina Denaro, Emanuela Passoni, Alice Indini, Gianluca Nazzaro, Giada Anna Beltramini, Valentina Benzecry, Giuseppe Colombo, Carolina Cauchi, Cinzia Solinas, Mario Scartozzi, Angelo Valerio Marzano, Ornella Garrone

“…Cemiplimab confirmed its effectiveness in elderly patients in a real-life setting, with no new safety concerns.…”
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A real-life comparison of pulmonary and nasal outcomes in patients with severe asthma and nasal polyposis treated with T2-biologics by Ulrike Förster-Ruhrmann, MD, Dafni Stergioudi, MD, Agnieszka J. Szczepek, PhD, Joachim W. Fluhr, MD, PhD, Torsten Zuberbier, MD, PhD, Heidi Olze, MD, PhD, Karl-Christian Bergmann, MD, PhD

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Cardiovascular and renal outcomes with SGLT2 inhibitors: Real-life observational studies in older patients with type 2 diabetes by André J. Scheen

“…In conclusion, observational studies in real-life conditions confirm previous results reported in placebo-controlled trials and a positive benefit/risk balance in elderly patients with T2DM at risk of heart failure and chronic kidney disease.…”
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Real-life effectiveness and safety of dupilumab in adolescents with atopic dermatitis: a 52-week single-center retrospective study by Luigi Gargiulo, Carlo Alberto Vignoli, Luciano Ibba, Andrea Cortese, Mario Valenti, Antonio Costanzo, Alessandra Narcisi

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