Nasal Symptoms in Asthmatic Patients under Treatment with Anti-IL-5 Monoclonal Antibodies. A Real-Life Cohort Study by Juan Maza-Solano, Christian Calvo-Henríquez, Isam Alobid, Marta Álvarez-Cendrero, Óscar Palomares, Ramón Moreno-Luna, Jaime Santos-Perez, Jaime González-García, Serafín Sánchez-Gómez

“…Three anti-IL-5 mAb: mepolizumab, reslizumab and benralizumab, have been tested through randomized clinical trials. In this real-life study, we aimed to describe the nasal effects of a cohort of asthmatic adults treated with anti-IL-5 mAb. …”
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A Ten-Year Real-Life Experience with Pazopanib in Uterine Leyomiosarcoma in Two High-Specialized Centers in Italy: Effectiveness and Safety by Mara Mantiero, Marta Bini, Maggie Polignano, Luca Porcu, Roberta Sanfilippo, Chiara Fabbroni, Gabriella Parma, Mariateresa Lapresa, Carmelo Calidona, Cecilia Silvestri, Andrea Franza, Francesco Raspagliesi, Nicoletta Colombo, Monika Ducceschi

“…To date, poor research on real-life data has been conducted. We aimed to assess the effectiveness and safety of the drug in everyday clinical practice. …”
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Assessing the cost-effectiveness of waiting list reduction strategies for a breast radiology department: a real-life case study by Annarita Fanizzi, Elisabetta Graps, Domenica Antonia Bavaro, Marco Farella, Samantha Bove, Francesco Campobasso, Maria Colomba Comes, Cristian Cristofaro, Daniele La Forgia, Martina Milella, Serena Iacovelli, Rossella Villani, Rahel Signorile, Alessio De Bartolo, Vito Lorusso, Raffaella Massafra

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Role of Serum Free Light Chain Assay in Relapsed/Refractory Multiple Myeloma. A Real-Life Unicentric Retrospective Study by Uros Markovic, Alessandra Romano, Claudia Bellofiore, Annalisa Condorelli, Bruno Garibaldi, Anna Bulla, Andrea Duminuco, Vittorio Del Fabro, Francesco Di Raimondo, Concetta Conticello

“…Serum free light chain (sFLC) assay is recommended for disease monitoring in oligo-secretory and micromolecular MM. Methods: In this real-life survey, a total of 130 relapsed/refractory MM patients treated at our center with at least three lines were investigated as a retrospective cohort. …”
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Marked Reduction of Oxidant Species after Sulfureous Crenotherapy in Females with Joint Diseases and Psoriasis: A Retrospective Real-Life Study by Maria Costantino, Valeria Conti, Graziamaria Corbi, Valentina Giudice, Francesco De Caro, Amelia Filippelli

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PB1940: REAL-LIFE EXPERIENCE OF THE IMMUNE RECONSTITUTION IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKAEMIA AND SMALL LYMPHOCYTIC LYMPHOMA TREATED WITH IBRUTINIB. by Belén Olivares Pérez, Francisco José Jiménez Nájar, Clara Aparicio Pérez, Ana Camila González Teomiro, Alfredo Pacheco Reyes, Margarita Fernández de la Mata

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Indicators of Potential Use of Electric Vehicles in Urban Areas: A Real-Life Survey-Based Study in Hail, Saudi Arabia by Abdulmohsen A. Al-fouzan, Radwan A. Almasri

“…This study aimed to uncover the attitudes, preferences, and perceptions of Hail residents toward electric vehicles (EVs) by employing a real-life survey-based approach. This paper presents an in-depth analysis of the potential adoption and impact of EVs to clarify the picture of the transition from using traditional vehicles to using EVs in Hail City, Saudi Arabia. …”
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Assessment of Patient Knowledge, Awareness, and Adherence in Heart Failure in a Real-Life Setting: Insights from Data Acquired in Pharmacies by Masatake Kobayashi, Christophe Wilcke, Nicolas Girerd

“…Background: Patient knowledge is crucial for managing and/or monitoring patients with heart failure (HF). However, “real-life” evidence of knowledge level and awareness in HF is yet to be explored. …”
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Effectiveness and safety of dupilumab in patients with chronic rhinosinusitis with nasal polyps and associated comorbidities: a multicentric prospective study in real life by Eustachio Nettis, Luisa Brussino, Vincenzo Patella, Laura Bonzano, Aikaterini Detoraki, Elisabetta Di Leo, Maria Maddalena Sirufo, Cristiano Caruso, Fabio Lodi Rizzini, Mariaelisabetta Conte, Mona-Rita Yacoub, Massimo Triggiani, Erminia Ridolo, Luigi Macchia, Giovanni Rolla, Raffaele Brancaccio, Amato De Paulis, Giuseppe Spadaro, Danilo Di Bona, Angela Maria D’Uggento, Lia Ginaldi, Francesco Gaeta, Eleonora Nucera, Kliljeda Jaubashi, Danilo Villalta, Lorenzo Dagna, Domenico Ciotta, Francesco Pucciarini, Diego Bagnasco, Giorgio Celi, Fulvia Chieco Bianchi, Lorenzo Cosmi, Maria Teresa Costantino, Maria Angiola Crivellaro, Simona D’Alò, Pietro del Biondo, Stefano Del Giacco, Mario Di Gioacchino, Linda Di Pietro, Elisabetta Favero, Sebastiano Gangemi, Gabriella Guarnieri, Enrico Heffler, Maria Stefania Leto Barone, Carla Lombardo, Francesca Losa, Andrea Matucci, Paola Lucia Minciullo, Paola Parronchi, Giovanni Passalacqua, Stefano Pucci, Oliviero Rossi, Lorenzo Salvati, Michele Schiappoli, Gianenrico Senna, Andrea Vianello, Alessandra Vultaggio, Yang Baoran, Cristoforo Incorvaia, Giorgio Walter Canonica

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PACE study: real-life Psoriasis Area and Severity Index (PASI) 100 response with biological agents in moderate-severe psoriasis by Carlo Giovanni Carrera, Paolo Dapavo, Piergiorgio Malagoli, Luigi Naldi, Luisa Arancio, Francesca Gaiani, Colin Gerard Egan, Marco Di Mercurio, Angelo Cattaneo

“…Background: Few studies have compared the use of different biologics in a real-life setting in plaque psoriasis patients. Objective: To compare the efficacy of biologics in psoriasis/psoriatic arthritis patients. …”
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Deep brain stimulation for treatment resistant obsessive compulsive disorder; an observational study with ten patients under real-life conditions by Mohamed A. Abdelnaim, Mohamed A. Abdelnaim, Verena Lang-Hambauer, Verena Lang-Hambauer, Tobias Hebel, Stefan Schoisswohl, Stefan Schoisswohl, Martin Schecklmann, Daniel Deuter, Daniel Deuter, Juergen Schlaier, Juergen Schlaier, Berthold Langguth, Berthold Langguth

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Effectiveness and Safety of Biosimilars in Pediatric Non-infectious Uveitis: Real-Life Data from the International AIDA Network Uveitis Registry by Maria Tarsia, Antonio Vitale, Carla Gaggiano, Jurgen Sota, Anna Maselli, Chiara Bellantonio, Silvana Guerriero, Rosanna Dammacco, Francesco La Torre, Gaafar Ragab, Mohamed Tharwat Hegazy, Alex Fonollosa, Maria Pia Paroli, Emanuela Del Giudice, Maria Cristina Maggio, Marco Cattalini, Lampros Fotis, Giovanni Conti, Angela Mauro, Adele Civino, Federico Diomeda, Alejandra de-la-Torre, Carlos Cifuentes-González, Samar Tharwat, José Hernández-Rodríguez, Verónica Gómez-Caverzaschi, Laura Pelegrín, Kalpana Babu, Vishali Gupta, Francesca Minoia, Piero Ruscitti, Stefania Costi, Luciana Breda, Saverio La Bella, Alessandro Conforti, Maria Antonietta Mazzei, Ester Carreño, Rana Hussein Amin, Salvatore Grosso, Bruno Frediani, Gian Marco Tosi, Alberto Balistreri, Luca Cantarini, Claudia Fabiani

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Use of artesunate in the treatment of severe imported malaria in France: review of the effectiveness and real-life safety in two French university hospitals by M. Bonsergent, M. Tching-Sin, S. Honoré, P. Bertault-Peres, A. Lepelletier, L. Flet, T. Perez

“…However, after 10 years of use in France, AS hasn’t yet received marketing authorization.The purpose of this study was to assess the real-life effectiveness and safety of AS in the treatment of SIM in two Hospitals in France. …”
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Improvement in severe asthma patients receiving biologics and factors associated with persistent insufficient control: a real-life national study by Laurent Guilleminault, Claire Camus, Chantal Raherison-Semjen, Audrey Capdepon, Arnaud Bourdin, Philippe Bonniaud, Stéphanie Fry, Gilles Devouassoux, François-Xavier Blanc, Christophe Pison, Clairelyne Dupin, Naji Khayath, Joelle Courdeau, Judith Valcke-Brossollet, Cécilia Nocent-Ejnaini, Fabien Rolland, Carmen Lamandi, Alain Proust, Anaig Ozier, Laurent Portel, Wanda Gaspard, Pauline Roux-Claude, Antoine Beurnier, Stéphanie Martinez, Jean-Marc Dot, Florence Hennegrave, Guillaume Vignal, Etienne Auvray, Nicolas Paleiron, Nicolas Just, Jean Miltgen, Maud Russier, Cécile Olivier, Camille Taillé, Alain Didier

“…Design: The Second Souffle study is a real-life prospective observational study endorsed by the Clinical Research Initiative in Severe Asthma: a Lever for Innovation & Science Network. …”
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Immune-Checkpoint-Inhibitor-Related Lung Toxicity: A Multicentre Real-Life Retrospective Portrait from Six Italian Centres by Paolo Cameli, Paola Faverio, Katia Ferrari, Viola Bonti, Stefania Marsili, Maria Antonietta Mazzei, Francesca Mazzoni, Maurizio Bartolucci, Vieri Scotti, Federica Bertolini, Fausto Barbieri, Cinzia Baldessari, Chiara Veronese, Roberto Boffi, Matteo Brighenti, Diego Cortinovis, Massimo Dominici, Alberto Pesci, Elena Bargagli, Fabrizio Luppi

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Influence of Clinical Factors on the Quality of Life in Romanian People with Epilepsy—A Follow-Up Study in Real-Life Clinical Practice by Ionut-Horia Cioriceanu, Dan-Alexandru Constantin, Elena Bobescu, Luigi Geo Marceanu, Liliana Rogozea

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Hematologic Malignancy Risk in Inflammatory Arthritis Patients Treated with TNF Inhibitors: The Real-Life Data from the HUR-BIO Registry by Emine Duran, Zeynep Ozge Ozturk, Emre Bilgin, Yahya Büyükaşık, Omer Dizdar, Gozde Kubra Yardimci, Bayram Farisogullari, Zehra Özsoy, Gizem Ayan, Gullu Sandal Uzun, Mustafa Ekici, Erdinc Unaldi, Levent Kilic, Ali Akdoğan, Omer Karadag, Şule Apraş Bilgen, Sedat Kiraz, Umut Kalyoncu, Ali Ihsan Ertenli

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Cemiplimab for Locally Advanced and Metastatic Cutaneous Squamous-Cell Carcinomas: Real-Life Experience from the French CAREPI Study Group by Candice Hober, Lisa Fredeau, Anne Pham-Ledard, Marouane Boubaya, Florian Herms, Philippe Celerier, François Aubin, Nathalie Beneton, Monica Dinulescu, Arnaud Jannic, Nicolas Meyer, Anne-Bénédicte Duval-Modeste, Laure Cesaire, Ève-Marie Neidhardt, Élodie Archier, Brigitte Dréno, Candice Lesage, Clémence Berthin, Nora Kramkimel, Florent Grange, Julie de Quatrebarbes, Pierre-Emmanuel Stoebner, Nicolas Poulalhon, Jean-Philippe Arnault, Safia Abed, Bertille Bonniaud, Sophie Darras, Valentine Heidelberger, Suzanne Devaux, Marie Moncourier, Laurent Misery, Sandrine Mansard, Maxime Etienne, Florence Brunet-Possenti, Caroline Jacobzone, Romain Lesbazeilles, François Skowron, Julia Sanchez, Stéphanie Catala, Mahtab Samimi, Youssef Tazi, Dominique Spaeth, Caroline Gaudy-Marqueste, Olivier Collard, Raoul Triller, Marc Pracht, Marc Dumas, Lucie Peuvrel, Pierre Combe, Olivier Lauche, Pierre Guillet, Yves Reguerre, Ingrid Kupfer-Bessaguet, David Solub, Amélie Schoeffler, Christophe Bedane, Gaëlle Quéreux, Sophie Dalac, Laurent Mortier, Ève Maubec

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Switch from Omalizumab to Benralizumab in Allergic Patients with Severe Eosinophilic Asthma: A Real-Life Experience from Southern Italy by Corrado Pelaia, Claudia Crimi, Santi Nolasco, Giovanna Elisiana Carpagnano, Raffaele Brancaccio, Enrico Buonamico, Raffaele Campisi, Claudia Gagliani, Vincenzo Patella, Girolamo Pelaia, Giuseppe Valenti, Nunzio Crimi

“…Within such a context, the aim of our real-life investigation was to verify whether allergic patients with severe eosinophilic asthma, not adequately controlled by an initial biologic treatment with omalizumab, could experience better therapeutic results from a pharmacologic shift to benralizumab. …”
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Sonidegib in Locally Advanced Basal Cell Carcinoma: A Monocentric Retrospective Experience and a Review of Published Real-Life Data by Gianluca Nazzaro, Valentina Benzecry, Maria A. Mattioli, Nerina Denaro, Giada A. Beltramini, Angelo V. Marzano, Emanuela Passoni

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