Treatment adherence and effect of concurrent statin intensity on the efficacy and safety of alirocumab in a real-life setting: results from ODYSSEY APPRISE by Maciej Banach, José Luis López-Sendon, Maurizio Averna, Bertrand Cariou, Megan Loy, Garen Manvelian, Isabela Batsu, Yann Poulouin, Daniel Gaudet

“…Treatment-emergent adverse events occurred in 65.2–75.1% and 68.0–76.3% of patients across statin and ezetimibe subgroups, respectively. Conclusions In a real-life setting, patient adherence to alirocumab was high. …”
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Real-Life Experience with Pomalidomide plus Low-Dose Dexamethasone in Patients with Relapsed and Refractory Multiple Myeloma: A Retrospective and Prospective Study by Maria Livia Del Giudice, Alessandro Gozzetti, Elisabetta Antonioli, Enrico Orciuolo, Francesco Ghio, Sara Ciofini, Veronica Candi, Giulia Fontanelli, Irene Attucci, Giuseppe Formica, Monica Bocchia, Sara Galimberti, Mario Petrini, Gabriele Buda

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P697: PONATINIB IN A REAL-LIFE SETTING: A RETROSPECTIVE ANALYSIS FROM THE MONITORING REGISTRIES OF THE ITALIAN MEDICINES AGENCY (AIFA) by M. Breccia, P. P. Olimpieri, S. Celant, O. M. Olimpieri, F. Pane, A. Iurlo, V. Summa, P. Corradini, P. Russo

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Control of Low-Density Lipoprotein Cholesterol in Secondary Prevention of Coronary Artery Disease in Real-Life Practice: The DAUSSET Study in French Cardiologists by Jean Ferrières, François Roubille, Michel Farnier, Patrick Jourdain, Denis Angoulvant, Franck Boccara, Nicolas Danchin

“…It aimed to describe real-life clinical practices for low-density lipoprotein (LDL) cholesterol control in the secondary prevention of CAD. …”
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Complete response to anti-interleukin-5 biologics in a real-life setting: results from the nationwide Danish Severe Asthma Register by Marianne Baastrup Soendergaard, Susanne Hansen, Anne-Sofie Bjerrum, Ole Hilberg, Sofie Lock-Johansson, Kjell Erik Julius Håkansson, Truls Sylvan Ingebrigtsen, Claus Rikard Johnsen, Linda Makowska Rasmussen, Anna von Bülow, Karin Dahl Assing, Johannes Martin Schmid, Charlotte Suppli Ulrik, Celeste Porsbjerg

“…However, patients eligible for these trials differ significantly compared with real-life severe asthma populations. Therefore, our aim was to explore efficacy in a real-life setting. …”
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P912: ADDING REFRACTORINESS STATUS TO LINES OF THERAPY BETTER DEFINE PROGNOSIS OF A REAL LIFE ITALIAN MULTIPLE MYELOMA POPULATION by Sonia More’, Laura Corvatta, Valentina Maria Manieri, Erika Morsia, Attilio Olivieri, Massimo Offidani

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The Use of HSQoL-24 in an Assessment of Quality-of-Life Impairment among Hidradenitis Suppurativa Patients: First Look at Real-Life Data by Piotr K. Krajewski, Servando E. Marrón, Manuel Gomez-Barrera, Lucía Tomas-Aragones, Yolanda Gilaberte-Calzada, Jacek C. Szepietowski

“…The study shows that the HSQoL-24 questionnaire is a reliable, HS-specific tool for measuring the QoL among patients with HS in real-life clinical settings.…”
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Evolution of the Therapeutic Management of Giant Cell Arteritis: Analysis of Real-Life Practices over Two Timeframes (2014–2017 and 2018–2020) by Hubert de Boysson, Anael Dumont, Paul Castan, Sophie Gallou, Jonathan Boutemy, Gwénola Maigné, Nicolas Martin Silva, Alexandre Nguyen, Samuel Deshayes, Achille Aouba

“…<b>Conclusions:</b> This real-life study showed a global change in GC management over time for GCA patients, with important variability among physicians’ practices.…”
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Characteristics and disease course of untreated patients with interstitial lung disease associated with systemic sclerosis in a real-life two-centre cohort by Oliver Distler, Cosimo Bruni, Anna-Maria Hoffmann-Vold, Suzana Jordan, Carina Mihai, Muriel Elhai, Marouane Boubaya, Rucsandra Dobrota, Øyvind Midtvedt, Mike Becker, Alexandru Garaiman, Håvard Fretheim, Imon Barua, Moritz Scheidegger, Hilde Jenssen Bjørkekjær

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Real-life effectiveness of transitioning from paliperidone palmitate 1-monthly to paliperidone palmitate 3-monthly long-acting injectable formulation by Olivier Corbeil, Anne-Marie Essiambre, Laurent Béchard, Audrey-Anne Roy, Maxime Huot-Lavoie, Sébastien Brodeur, Ranjith Chandrasena, Chantale Thériault, Candice Crocker, Jean-Pierre Melun, Phil Tibbo, Marie-France Demers, Marc-André Roy

“…Randomized clinical trials (RCTs) have demonstrated the efficacy of paliperidone palmitate 3-monthly (PP3M) for psychotic relapse prevention in schizophrenia, but it remains poorly documented among individuals treated in real-life settings who can benefit the most out of LAIs. …”
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Classifying autism in a clinical population based on motion synchrony: a proof-of-concept study using real-life diagnostic interviews by Jana Christina Koehler, Mark Sen Dong, Da-Yea Song, Guiyoung Bong, Nikolaos Koutsouleris, Heejeong Yoo, Christine M. Falter-Wagner

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Safety and Efficacy of Rivaroxaban for Extended-Phase Anticoagulation of Patients with Unprovoked or Recurrent Venous Thromboembolism: Real-Life Data from the MAC Project by Cristiano Bortoluzzi, Enrico Bernardi, Giuseppe Camporese, Franco Noventa, Davide Ceccato, Chiara Tonello, Ngoc Vo Hong, Elena Campello, Chiara Simion, Egidio Imbalzano, Pierpaolo Di Micco, Elena Callegari, Paolo Simioni

“…The project aims to collect real-life clinical information in unselected patients given oral anticoagulants for VTE over a 5-year follow-up period. …”
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Validation of a German-language modified Rankin Scale structured telephone interview at 3 months in a real-life stroke cohort by Lennart Steffen Milles, Doreen Pommeranz, Woon Hyung Chae, Jordi Kühne Escolà, Christoph Kleinschnitz, Martin Köhrmann, Benedikt Frank

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A Sad Bird Learning to Fly: A Dark Real-Life Tale about the Experience of a Patient Suffering Domestic Violence by Thiago Henrique Roza, Sarah Aline Roza

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Real-Life Outcomes of a Multicomponent Exercise Intervention in Community-Dwelling Frail Older Adults and Its Association with Nutritional-Related Factors by Fernando Millan-Domingo, Francisco Jose Tarazona-Santabalbina, Aitor Carretero, Gloria Olaso-Gonzalez, Jose Viña, Maria Carmen Gomez-Cabrera

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A Laboratory-Based Study on Multiple Biomarker Testing in the Diagnosis of COVID-19-Associated Pulmonary Aspergillosis (CAPA): Real-Life Data by Cornelia Lass-Flörl, Miriam Knoll, Wilfried Posch, Michael Joannidis, Timo Mayerhöfer, Robert Breitkopf, Romuald Bellmann

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Improvement of Overall Survival Using TKIs as Salvage Therapy in Advanced Thyroid Carcinoma: Real-Life Data on a Single Center Experience by Lucia Brilli, Cristina Dalmiglio, Tania Pilli, Filomena Barbato, Fabio Maino, Marco Capezzone, Alessandra Cartocci, Maria Grazia Castagna

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Patterns of the physical, cognitive, and mental health status of older individuals in a real-life primary care setting and differences in coping styles by Thomas Wittlinger, Sanja Bekić, Sanja Bekić, Silva Guljaš, Vlatka Periša, Mile Volarić, Ljiljana Trtica Majnarić, Ljiljana Trtica Majnarić

“…Mental health disorders, anxiety and depression, are common in older people with multimorbidity, in particular those with functional or sensory deficits, and frailty.PurposeThe aim of this study was to show how physical frailty, cognitive impairments and mental disorders, cluster in the real life setting of older primary care (PC) patients, and how these clusters relate to age, comorbidities, stressful events, and coping strategies. …”
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Ecological validity of a deep learning algorithm to detect gait events from real-life walking bouts in mobility-limiting diseases by Robbin Romijnders, Robbin Romijnders, Francesca Salis, Clint Hansen, Arne Küderle, Anisoara Paraschiv-Ionescu, Andrea Cereatti, Lisa Alcock, Kamiar Aminian, Clemens Becker, Stefano Bertuletti, Tecla Bonci, Tecla Bonci, Philip Brown, Ellen Buckley, Ellen Buckley, Alma Cantu, Anne-Elie Carsin, Anne-Elie Carsin, Anne-Elie Carsin, Marco Caruso, Brian Caulfield, Brian Caulfield, Lorenzo Chiari, Lorenzo Chiari, Ilaria D'Ascanio, Silvia Del Din, Silvia Del Din, Björn Eskofier, Sara Johansson Fernstad, Marceli Stanislaw Fröhlich, Judith Garcia Aymerich, Judith Garcia Aymerich, Judith Garcia Aymerich, Eran Gazit, Jeffrey M. Hausdorff, Jeffrey M. Hausdorff, Hugo Hiden, Emily Hume, Alison Keogh, Alison Keogh, Cameron Kirk, Felix Kluge, Felix Kluge, Sarah Koch, Sarah Koch, Sarah Koch, Claudia Mazzà, Claudia Mazzà, Dimitrios Megaritis, Encarna Micó-Amigo, Arne Müller, Luca Palmerini, Luca Palmerini, Lynn Rochester, Lynn Rochester, Lars Schwickert, Kirsty Scott, Kirsty Scott, Basil Sharrack, David Singleton, David Singleton, Abolfazl Soltani, Abolfazl Soltani, Martin Ullrich, Beatrix Vereijken, Ioannis Vogiatzis, Alison Yarnall, Alison Yarnall, Gerhard Schmidt, Walter Maetzler

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An evaluation of factors affecting pain during transrectal ultrasonographic prostate biopsy: a real-life scenario in a retrospective cohort study by Oğuz Özden Cebeci, Alp Ozkan

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