Ceft-to-Ceft Study: Real-Life Experience with Ceftaroline and Ceftobiprole in Treatment of the Principal Infectious Syndromes in a Spanish Multicenter Hospital Cohort by Daniel Arnés García, Inés Pitto-Robles, Jorge Calderón Parra, Marina Calvo Salvador, Carmen Herrero Rodríguez, Laura Gisbert, Carmen Hidalgo-Tenorio

“…Background: To compare the real-life effectiveness and safety of ceftaroline fosamil (ceftaroline-F) and ceftobiprole medocaril (ceftobiprole-M) for infections in hospitalized patients. …”
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What is in three words? Exploring a three-word methodology for assessing impressions of a social robot encounter online and in real life by Damholdt Malene Flensborg, Christina Vestergaard, Kryvous Anna, Smedegaard Catharina Vesterager, Seibt Johanna

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Influence of Lithium-Ion-Battery Equivalent Circuit Model Parameter Dependencies and Architectures on the Predicted Heat Generation in Real-Life Drive Cycles by Marcus Auch, Timo Kuthada, Sascha Giese, Andreas Wagner

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A novel generalized Weibull Poisson G class of continuous probabilistic distributions with some copulas, properties and applications to real-life datasets by Atef F. Hashem, M. A. Abdelkawy, Abdisalam Hassan Muse, Haitham M. Yousof

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Early liver function improvement following successful treatment of chronic hepatitis C in patients with decompensated cirrhosis: a real-life study by Mariana Sandoval Lourenço, Patricia Momoyo Y. Zitelli, Marlone Cunha-Silva, Arthur Ivan N. Oliveira, Roque Gabriel Rezende de Lima, Evandro de Oliveira Souza, Claudia P. Oliveira, Tiago Sevá-Pereira, Flair J. Carrilho, Mario G. Pessoa, Daniel F. Mazo

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In-depth assessment of quality of life and real life impact of mild traumatic brain injury in elderly by means of a focus group study by Rebeca Alejandra Gavrila Laic, Jos Vander Sloten, Bart Depreitere

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First-Line Pharmacotherapies and Survival among Patients Diagnosed with Non-Resectable NSCLC: A Real-Life Setting Study with Gender Prospective by Andrea Spini, Rosa Gini, Pietro Rosellini, Allison Singier, Cristiana Bellan, Alessandra Pascucci, Lorenzo Leoncini, Clément Mathieu, Ignazio Martellucci, Folco Furiesi, Silvano Giorgi, Sandra Donnini, Giuseppe Roberto, Marina Ziche, Francesco Salvo

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Real-Life Experience of the Effects of Cladribine Tablets on Lymphocyte Subsets and Serum Neurofilament Light Chain Levels in Relapsing Multiple Sclerosis Patients by Damiano Paolicelli, Maddalena Ruggieri, Alessia Manni, Concetta D. Gargano, Graziana Carleo, Claudia Palazzo, Antonio Iaffaldano, Luca Bollo, Tommaso Guerra, Annalisa Saracino, Antonio Frigeri, Pietro Iaffaldano, Maria Trojano

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Clinical and Functional Effects of Inhaled Dual Therapy Umeclidinium/Vilanterol in Patients with Chronic Obstructive Pulmonary Disease: A Real-Life Study by Pelaia C, Ferrante Bannera A, Rotundo FL, Tropea FG, Armentaro G, Maglio A, Sciacqua A, Vatrella A, Pelaia G

“…In particular, the reported changes of mMRC/CAT scores and COPD exacerbation numbers were significantly correlated with UMEC/VI–induced modifications of TLC, RV, FVC and FEV1.Conclusion: In conclusion, our study corroborates in a real-life context the effectiveness of UMEC/VI in COPD treatment. …”
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Transcatheter Mitral Repair for Functional Mitral Regurgitation According to Left Ventricular Function: A Real-Life Propensity-Score Matched Study by Isaac Pascual, Fernando Carrasco-Chinchilla, Tomas Benito-Gonzalez, Chi Hion Li, Pablo Avanzas, Luis Nombela-Franco, Manuel Pan, Ana Serrador Frutos, Xavier Freixa, Ramiro Trillo-Nouche, Rosa A. Hernández-Antolín, Leire Andraka Ikazuriaga, Ignacio Cruz-Gonzalez, Jose R. López-Mínguez, Jose L. Diez, Alberto Berenguer-Jofresa, Juan Sanchis, Valeriano Ruiz-Quevedo, Cristobal Urbano-Carrillo, Juan F. Oteo Dominguez, Maria R. Ortas-Nadal, Eduardo Molina Navarro, Xavier Carrillo, Juan H. Alonso-Briales, Felipe Fernández-Vázquez, Luis Asmarats Serra, Daniel Hernandez-Vaquero, Pilar Jimenez-Quevedo, Dolores Mesa, Tania Rodríguez-Gabella, Ander Regueiro, Amparo Martinez Monzonís, Luisa Salido Tahoces, Lara Ruiz Gomez, Blanca Trejo-Velasco, Victor M. Becerra-Muñoz, Carmen Garrote-Coloma, Estafanía Fernández Peregrina, Rebeca Lorca, Jose A. De Agustín, Miguel Romero, Ignacio J. Amat-Santos, Manel Sabaté, Ana B. Cid Alvarez, Jose M. Hernandez-Garcia, Javier Gualis, Dabit Arzamendi, Cesar Moris, Gabriela Tirado-Conte, Angel Sánchez-Recalde, Rodrigo Estevez-Loureiro

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A new cure model that corrects for increased risk of non-cancer death: analysis of reliability and robustness, and application to real-life data by Laura Botta, Juste Goungounga, Riccardo Capocaccia, Gaelle Romain, Marc Colonna, Gemma Gatta, Olayidé Boussari, Valérie Jooste

“…When applied to colon cancer real-life data, cure fractions estimated using the proposed model were higher than those in the conventional model, e.g. 5% higher in males at age 60 (57% vs. 52%). …”
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A Real-Life Survey of Venous Thromboembolic Events Occurring in Myeloma Patients Treated in Third Line with Second-Generation Novel Agents by Valeria Calafiore, Silvia Giamporcaro, Concetta Conticello, Alessandra Romano, Marina Parisi, Gaetano Giuffrida, Daniele Tibullo, Francesco Di Raimondo, Salvatore Santo Signorelli

“…No VTE occurred in patients treated with daratumumab. Thus, our real-life experience documents that (1) in RRMM patients treated with continuative regimens of third line, the incidence of VTE is similar to the setting of newly-diagnosed patients; (2) many patients in real-life received prophylaxis with ASA, irrespective of the risk classification; (3) the IMPEDE VTE score seems to be more appropriate to define the risk categories. …”
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Efficacy and safety of intravenous ferric carboxymaltose in iron deficiency anemia; Real-life data from Turkey, a single center experience by Ali Eser, Nang Hseng Kyio

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Real-life long-term outcomes of upfront surgery in patients with resectable stage I-IIIA non-small cell lung cancer by Bitenc Marko, Cufer Tanja, Kern Izidor, Miklavcic Martina, Petrovic Sabrina, Groznik Vida, Sadikov Aleksander

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Clinical response trajectories and drug persistence in systemic lupus erythematosus patients on belimumab treatment: A real-life, multicentre observational study by Myrto Nikoloudaki, Myrto Nikoloudaki, Dionysis Nikolopoulos, Sofia Koutsoviti, Irini Flouri, Irini Flouri, Noemin Kapsala, Argyro Repa, Argyro Repa, Pelagia Katsimbri, Evangelos Theotikos, Sofia Pitsigavdaki, Sofia Pitsigavdaki, Katerina Pateromichelaki, Katerina Pateromichelaki, Antonios Bertsias, Antonios Bertsias, Antonia Elezoglou, Prodromos Sidiropoulos, Prodromos Sidiropoulos, Prodromos Sidiropoulos, Antonis Fanouriakis, Antonis Fanouriakis, Dimitrios Boumpas, Dimitrios Boumpas, George Bertsias, George Bertsias, George Bertsias

“…Although severe flares were reduced, flares were not uncommon (58.0%) and contributed to treatment stops (odds ratio [OR] 1.73 per major flare; 95% CI 1.09-2.75) and damage accrual (OR 1.83 per mild/moderate flare; 95% CI 1.15-2.93).ConclusionsIn a real-life setting with predominant long-standing SLE, belimumab was effective in the majority of patients, facilitating the achievement of therapeutic targets. …”
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Nonlinear Heart Rate Variability features for real-life stress detection. Case study: students under stress due to university examination by Melillo Paolo, Bracale Marcello, Pecchia Leandro

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Impact of Anti-IL5 Therapies on Patients with Severe Uncontrolled Asthma and Possible Predictive Biomarkers of Response: A Real-Life Study by Susana Rojo-Tolosa, María Victoria González-Gutiérrez, Gonzalo Jiménez-Gálvez, José Antonio Sánchez-Martínez, Laura Elena Pineda-Lancheros, José María Gálvez-Navas, Alberto Jiménez-Morales, Cristina Pérez-Ramírez, Concepción Morales-García

“…The objective of this study was to evaluate, in real life, the clinical improvement of patients with SUA treated with anti-interleukin 5 (IL5) therapies: mepolizumab and benralizumab, together with the search for biomarkers associated with the response. …”
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Diagnostic performance evaluation of urine HIV-1 antibody rapid test kits in a real-life routine care setting in China by Huanhuan Chen, Qiuying Zhu, Guanghua Lan, Yuhua Ruan, Mei Lin, Shujia Liang, Jianjun Li, Huaxiang Lu, Guangjie Tan, Xianwu Pang, Xianmin Ge, Yunxian Huang, Zhenqiang Chen, Shizhen Zhang, Wenlong Cai

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Bleeding complications with clopidogrel or ticagrelor in ST-elevation myocardial infarction patients – A real life cohort study of two treatment strategies by Joakim Alfredsson, Kime Omar, József Csog, Dimitrios Venetsanos, Magnus Janzon, Mattias Ekstedt

“…Larger studies are needed to determine whether bleeding complications off-sets benefits with a more potent DAPT strategy in older and more comorbid real-life patients. Keywords: Myocardial infarction, Ticagrelor, Clopidogrel, Bleeding complications…”
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Etiology of Anemia and Risk Factors of Mortality among Hospitalized Patients: A Real-Life Retrospective Study in a Tertiary Center in Greece by Petros Ioannou, Andria Papazachariou, Maria Tsafaridou, Ioannis E. Koutroubakis, Diamantis P. Kofteridis

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