Percorso diagnostico-terapeutico e modello organizzativo per l’erogazione della terapia genica nelle distrofie retiniche ereditarie in real-life by Francesco Bandello, Maurizio Battaglia Parodi, Leonardo Colombo, Fabrizio Giansanti, Marcello Pani, Francesco Parmeggiani, Ugo Procoli, Stanislao Rizzo, Annalisa Scopinaro, Andrea Sodi, Annamaria Staiano, Giovanni Staurenghi, Francesca Simonelli

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Efficacy of Bendamustine, Pomalidomide, and Dexamethasone (BPD) Regimen in Relapsed/Refractory Extramedullary Myeloma: A Retrospective Single-Centre Study, Real-Life Experience by İbrahim Halil Açar, Birol Güvenç

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Prognostic factors, effectiveness and safety of endoscopic balloon dilatation for de novo and anastomotic strictures in Crohn’s disease—A multicenter “real life” study by Anita Bálint, Dalma Törőcsik, Károly Palatka, Zoltán Szepes, Mónika Szűcs, Ferenci Tamás, Ferenc Nagy, Klaudia Farkas, Anna Fábián, Renáta Bor, Ágnes Milassin, Mariann Rutka, Tamás Molnár

“…Introduction: Crohn’s disease (CD) is a chronic inflammatory disease which is frequently complicated by obstructive symptoms secondary to development of intestinal strictures. The aim of this “real life” study was to assess the effectiveness, safety and outcome of endoscopic balloon dilatation (EBD) in de novo vs. anastomotic stenoses. …”
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PB2527: COMPARING REAL-LIFE VERSUS PREDICTED PARAMETERS WITH OPTIA SPECTRA IN RED BLOOD CELL EXCHANGE IN SICKLE-CELL DISEASE PATIENTS by Pablo Palomo Rumschisky, Maria Tenorio Núñez, Kyra Velázquez Kennedy, Ana Jiménez Martín, Ana Vallés Carbonero, Alberto González Rodríguez, Blanca De Felipe Noguerales, Lucia Bolea, Francisco Lopez Jimenez, Gemma Moreno-Jiménez

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Tralokinumab rapidly improves subjective symptoms and quality of life in patients with moderate-to-severe atopic dermatitis: a real-life 16-week experience by Luigi Gargiulo, Luciano Ibba, Carlo Alberto Vignoli, Paola Facheris, Mario Valenti, Antonio Costanzo, Alessandra Narcisi

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Real-Life Experience of Molnupiravir in Hospitalized Patients Who Developed SARS-CoV2-Infection: Preliminary Results from CORACLE Registry by Tommaso Lupia, Silvia Corcione, Nour Shbaklo, Lucio Boglione, Stefano Torresan, Simone Mornese Pinna, Barbara Rizzello, Roberta Bosio, Valentina Fornari, Maria Teresa Brusa, Silvio Borrè, Francesco Giuseppe De Rosa

“…Real-life experience of molnupiravir treatment is lacking, especially in people hospitalized for underlying diseases not related to COVID-19. …”
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Real-Life Experience of Continuously Infused Ceftolozane/Tazobactam in Patients with Bronchiectasis and Multidrug-Resistant <i>Pseudomonas aeruginosa</i> Infection in the Outpatient Setting by Francesco Venuti, Alberto Gaviraghi, Amedeo De Nicolò, Giacomo Stroffolini, Bianca Maria Longo, Alessia Di Vincenzo, Fabio Antonino Ranzani, Matilde Quaranta, Francesca Romano, Eleonora Catellani, Carlotta Marchiaro, Giacoma Cinnirella, Antonio D’Avolio, Stefano Bonora, Andrea Calcagno

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Stopping Onabotulinum Treatment after the First Two Cycles Might Not Be Justified: Results of a Real-life Monocentric Prospective Study in Chronic Migraine by Paola Sarchielli, Michele Romoli, Ilenia Corbelli, Laura Bernetti, Angela Verzina, Elona Brahimi, Paolo Eusebi, Stefano Caproni, Paolo Calabresi, Paolo Calabresi

“…This prospective study aimed to define, in real-life setting, the evolution of the response to OnabotA over five cycles of treatment among patients non-responding to cycle 1. …”
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“I Don’t Think I Have an Attention Span for Real Life Anymore”: Excessive Stimulation, Sense of Meaninglessness, and Boredom in Sam Levinson’s Euphoria by Anna Pochmara

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Adalimumab Biosimilar GP2017 versus Adalimumab Originator in Treating Patients with Inflammatory Bowel Diseases: A Real-Life, Multicenter, Observational Study by Giammarco Mocci, Giorgia Bodini, Leonardo Allegretta, Alessia Immacolata Cazzato, Stefania Chiri, Giovanni Aragona, Patrizia Perazzo, Antonio Ferronato, Maria Giovanna Graziani, Cristiano Pagnini, Costantino Zampaletta, Camilla Graziosi, Marcello Picchio, Walter Elisei, Giovanni Maconi, Antonio Tursi

“…We compared the efficacy and safety of GP2017 versus originator in IBD outpatients in an Italian real-life setting. This retrospective analysis enrolled consecutive IBD patients with complete clinical, laboratory, and endoscopic data. …”
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Dose optimization strategy of the tyrosine kinase inhibitors imatinib, dasatinib, and nilotinib for chronic myeloid leukemia: From clinical trials to real-life settings by Fang Cheng, Fang Cheng, Fang Cheng, Qiang Li, Qiang Li, Zheng Cui, Zheng Cui, Mei Hong, Weiming Li, Yu Zhang, Yu Zhang

“…This review focuses mainly on the latest research of dose optimization of imatinib, dasatinib, and nilotinib in CML clinical trials and real-life settings. We consider dose reduction in newly diagnosed patients, or in optimal response, or for improving AEs, either as a prelude to treatment-free remission (TFR) or as maintenance therapy in those patients unable to discontinue TKIs therapy. …”
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Effects of nusinersen after one year of treatment in 123 children with SMA type 1 or 2: a French real-life observational study by Frédérique Audic, Marta Gomez Garcia de la Banda, Delphine Bernoux, Paola Ramirez-Garcia, Julien Durigneux, Christine Barnerias, Arnaud Isapof, Jean-Marie Cuisset, Claude Cances, Christian Richelme, Carole Vuillerot, Vincent Laugel, Juliette Ropars, Cécilia Altuzarra, Caroline Espil-Taris, Ulrike Walther-Louvier, Pascal Sabouraud, Mondher Chouchane, Catherine Vanhulle, Valérie Trommsdorff, Anne Pervillé, Hervé Testard, Emmanuelle Lagrue, Catherine Sarret, Anne-Laude Avice, Pierre Beze-Beyrie, Vanessa Pauly, Susana Quijano-Roy, Brigitte Chabrol, Isabelle Desguerre

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India's whole of the government and whole of the society approach for behavior change communication (BCC) strategy – An opportunity to learn BCC in a real-life situation by Sunder Lal

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Long-term outcomes of third-line therapy with tyrosine kinase inhibitors in chronic phase chronic myeloid leukemia: A real-life experience by Tamara Chitanava, Iuliia Matvienko, Vasily Shuvaev, Sergey Voloshin, Irina Martynkevich, Yulia Vlasova, Elizaveta Efremova, Ekaterina Mileeva, Anna Pirkhalo, Taiana Makarova, Roman Vlasik, Elena Karyagina, Natalia Il`ina, Nadezhda Medvedeva, Natalia Dorofeeva, Tatiana Shneider, Nadia Siordiya, Olga Kulemina, Olga Kulemina, Evgenia Sbityakova, Natalia Lazorko, Julia Alexeeva, Dmitrii Motorin, Dmitrii Motorin, Elena Morozova, Elza Lomaia, Elza Lomaia

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Machine-learning predictions for acute kidney injuries after coronary artery bypass grafting: a real-life muticenter retrospective cohort study by Tianchen Jia, Kai Xu, Yun Bai, Mengwei Lv, Lingtong Shan, Wei Li, Xiaobin Zhang, Zhi Li, Zhenhua Wang, Xin Zhao, Mingliang Li, Yangyang Zhang

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Gynecological complications in long-term survivors after allogeneic hematopoietic cell transplantation—a single-center real-life cross-sectional study by Huina Su, Xinyu Zhou, Yanli Zhao, Yue Lu, DeYan Liu, Janping Zhang, Xin Yang

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Real-Life Data on the Efficacy and Safety of Letermovir for Primary Prophylaxis of Cytomegalovirus in Allogeneic Hematopoietic Stem Cell Recipients: A Single-Center Analysis by Martyna Wlodarczyk, Agata Wieczorkiewicz-Kabut, Krzysztof Białas, Anna Koclęga, Izabela Noster, Patrycja Zielińska, Grzegorz Helbig

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Sentinel lymph node biopsy for cutaneous melanoma in a real life setting: analysis of 47 cases treated at a private clinic in Brazil by Isabella Parente Almeida, Maria Isabel Ramos Saraiva, Maria Cristina de Lorenzo Messina, João Pereira Duprat, Luiz Guilherme Martins Castro

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Real Life Population Pharmacokinetics Modelling of Eight Factors VIII in Patients with Severe Haemophilia A: Is It Always Relevant to Switch to an Extended Half-Life? by Quentin Allard, Zoubir Djerada, Claire Pouplard, Yohann Repessé, Dominique Desprez, Hubert Galinat, Birgit Frotscher, Claire Berger, Annie Harroche, Anne Ryman, Claire Flaujac, Pierre Chamouni, Benoît Guillet, Fabienne Volot, Jean Szymezak, Philippe Nguyen, Yoann Cazaubon

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Last Resort Antibiotics Costs and Reimbursement Analysis of Real-Life ICU Patients with Pneumonia Caused by Multidrug-Resistant Gram-Negative Bacteria in Germany by Julia Jeck, Sebastian M. Wingen-Heimann, Florian Jakobs, Jennifer Franz, Christoph T. Baltin, Anna Kron, Boris Böll, Matthias Kochanek, Oliver A. Cornely, Florian Kron

“…Retrospective analyses based on medical charts and real-life reimbursement data included patients with pneumonia due to MDR-GNB treated in intensive care units (ICU) of a German tertiary care hospital (University Hospital Cologne) between January 2017 and December 2020. …”
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