Up-regulation of Mcl-1 and Bak by coronavirus infection of human, avian and animal cells modulates apoptosis and viral replication by Zhong, Yanxin., Liao, Ying., Fang, Shouguo., Tam, James P., Liu, Ding Xiang.

“…Furthermore, IBV infection-induced up-regulation of GADD153 regulated the expression of Mcl-1. …”
Get full text
Get full text

Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitis by Alvarez-Martinez, M, Cox, LS, Pearson, CF, Branchett, WJ, Chakravarty, P, Wu, X, Slawinski, H, Al-Dibouni, A, Samelis, VA, Gabryšová, L, Priestnall, SL, Suárez-Bonnet, A, Mikolajczak, A, Briscoe, J, Powrie, F, O'Garra, A

“…Here, we use single-cell RNA sequencing of colon lamina propria leukocytes (LPLs) along with RNA-seq and ATAC-seq of purified CD4⁺ T cells to show that the transcription factors Blimp-1 (encoded by Prdm1) and c-Maf co-dominantly regulate Il10 while negatively regulating proinflammatory cytokines in effector T cells. …”

Enhancing representation of data-scarce reservoir-regulated river basins using a hybrid DL-process based approach by Deng, L, Zhang, X, Slater, LJE

“…River discharge estimation in regulated river basins requires the inclusion of specific reservoir operation modules. …”

Investigating the use of neurofeedback to promote self-regulation of cortical motor activities as a potential rehabilitation tool post-stroke by Huang, Y

“…Therefore, a potential rehabilitative strategy for post-stroke motor recovery is promoting self-regulation of cortical motor activity to rebalance this abnormal brain activation pattern.…”

Deadbeat control for a single-inductor multiple-input multiple-output dc-dc converter by Wang, Benfei, Zhang, Xinan, Ye, Jian, Gooi, Hoay Beng

Subjects: Get full text

Partial desensitization of MYC2 transcription factor alters the interaction with jasmonate signaling components and affects specialized metabolism by Hou, Xin, Singh, Sanjay Kumar, Werkman, Joshua R., Liu, Yongliang, Yuan, Qinghua, Wu, Xia, Patra, Barunava, Sui, Xueyi, Lyu, Ruiqing, Wang, Bingwu, Liu, Xiaoyu, Li, Yongqing, Ma, Wei, Pattanaik, Sitakanta, Yuan, Ling

Subjects: Get full text

Exploring the moderating role of expressive suppression in the relationship between psychopathy and aggression by Maria, Dayla

Subjects: Get full text

A LDO regulator with weighted current feedback technique for 0.47nF-10nF capacitive load by Tan, Xiao Liang, Chong, Sau Siong, Chan, Pak Kwong, Dasgupta, Uday

“…Besides, it provides good regulator loop gain and fast transient response. Validated by UMC 65 nm CMOS process, the simulation and measurement results have shown that the WCF LDO regulator can operate at a load capacitance (CL) range from 470 pF to 10 nF with only 3.8 pF compensation capacitor. …”
Get full text
Get full text

Relationships among emotion regulation, depression, anxiety, stress, and physical health-related quality of life in coronary heart disease patients by Ng, Min Geng

“…Coronary heart disease (CHD) is the third leading cause of death in Singapore. Although emotion regulation is a significant determinant of CHD patient’s quality of life, not many studies have assessed the impact of change in emotion regulation on physical functioning over time. …”
Get full text

Oncofetal HMGA2 attenuates genotoxic damage induced by topoisomerase II target compounds through the regulation of local DNA topology by Ahmed, Syed Moiz, Dröge, Peter

Get full text

Guiding transition metal-doped hollow cerium tandem nanozymes with elaborately regulated multi-enzymatic activities for intensive chemodynamic therapy by Dong, Shuming, Dong, Yushan, Liu, Bin, Liu, Jing, Liu, Shikai, Zhao, Zhiyu, Li, Wenting, Tian, Boshi, Zhao, Ruoxi, He, Fei, Gai, Shili, Xie, Ying, Yang, Piaoping, Zhao, Yanli

“…This work presents a powerful paradigm to achieve intensive NCDT efficacy by simultaneously regulating multi-enzymatic activities of Ce-based nanozymes and perturbing the H2O2 homeostasis in tumor microenvironment.…”
Get full text

Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr by Zhang, Yingdan, Chew, Alvin Bing Liang, Wang, Jing, Yuan, Mingjun, Yam, Joey Kuok Hoong, Luo, Dahai, Yang, Liang

“…Here, we identify P. aeruginosa's global virulence factor regulator Vfr as one target of auranofin. We report the mechanistic insights into the inhibitory mechanism of auranofin and gold(I) analogues to Vfr through structural, biophysical, and phenotypic inhibition studies. …”
Get full text

The design of a CMOS only low-power low-voltage low-dropout voltage regulator (LDO) with an embedded voltage reference by Xie, Xinzhe

Subjects: “…Low-dropout (LDO) voltage regulator…”
Get full text

Congenital myasthenic syndromes: characterisation of a new animal model, exploring potential novel therapies and assessing the outcome of COVID-19 infection by Alabaf, S

Subjects: “…Allosteric regulation…”

A 0.9-µ A quiescent current output-capacitorless LDO regulator with adaptive power transistors in 65-nm CMOS by Chong, Sau Siong, Chan, Pak Kwong

“…An ultra-low quiescent current output-capacitorless low-dropout (OCL-LDO) regulator with adaptive power transistors technique is presented in this paper. …”
Get full text
Get full text
Get full text

The dual GGDEF/EAL domain enzyme PA0285 is a Pseudomonas species housekeeping phosphodiesterase regulating early attachment and biofilm architecture by Eilers, Kira, Yam, Joey Kuok Hoong, Liu, Xianghui, Goh, Yu Fen, To, Ka-Ning, Paracuellos, Patricia, Morton, Richard, Brizuela, Jaime, Yong, Adeline Mei Hui, Givskov, Michael, Freibert, Sven-Andreas, Bange, Gert, Rice, Scott A., Steinchen, Wieland, Filloux, Alain

Get full text

Identification of potential common cyclic-di-GMP regulated biomarkers among three gram negative bacteria via transcriptomic and metabolomic profiling by Cai, Zhao

“…The results indicated that RpoN modulates virulence secretion through a PQS quorum sensing regulator, pqsR. This study provides evidence for the possible detection and diagnosis of biofilm infections in clinical prospective using c-di-GMP regulated metabolites; it also demonstrates the complex connections and regulations among global regulators at the same time.…”
Get full text

Enhancing E. coli tolerance towards oxidative stress via engineering its global regulator cAMP Receptor Protein (CRP) by Basak, Souvik, Jiang, Rongrong

“…Here, we aim to improve E. coli performance under oxidative stress via engineering its global regulator cAMP receptor protein (CRP), which can directly or indirectly regulate redox-sensing regulators SoxR and OxyR, and other ~400 genes in E. coli. …”
Get full text
Get full text

Voltage and frequency stability enhancement with an automatic voltage regulator and power system stabilizer in a ring-structured power system post generator loss by Zetty Adibah, Kamaruzzaman, Nur Zahirah, Mohd Ali, Ahmad Syahiman, Mohd Shah

“…This study analyses the transient stability of the IEEE 9-bus test system in the context of generator loss and delayed circuit breaker response, emphasizing the impact of Automatic Voltage Regulator (AVR) and Power System Stabilizer (PSS) on damping reduction and transient recovery time. …”
Get full text

The Tudor domain protein Tapas, a homolog of the vertebrate Tdrd7, functions in the piRNA pathway to regulate retrotransposons in germline of Drosophila melanogaster by Patil, Veena S., Anand, Amit, Chakrabarti, Alisha, Kai, Toshie

Get full text
Get full text