Plasmacytoid dendritic cells are central regulators of the humoral ChAdOx1 nCoV-19 vaccine response in a human tonsil organoid model by Provine, N, Pudjohartono, M, Powell, K, Ferry, H, Barnes, E, Klenerman, P

Regulation of microRNA degradation in Caenorhabditis elegans via the E3 ubiquitin ligase EBAX-1 by Stubna, Michael William

“…Animal genomes encode hundreds of miRNAs that, together, regulate a majority of mRNAs and tune spatiotemporal gene expression programs. …”
Get full text
Get full text

CD1d‐mediated lipid presentation by CD11c+ cells regulates intestinal homeostasis by Sáez de Guinoa, Julia, Jimeno, Rebeca, Gaya, Mauro, Kipling, David, Garzón, María J., Dunn‐Walters, Deborah, Ubeda, Carles, Barral, Patricia

“…Natural killer T (NKT) cells, which recognize CD1d‐restricted microbial lipids and self‐lipids, contribute to the regulation of mucosal immunity, yet the mechanisms underlying their functions remain poorly understood. …”
Get full text

Subcellular localization of monoglucosyldiacylglycerol synthase in Synechocystis sp. PCC6803 and its unique regulation by lipid environment by Selão, Tiago Toscano, Zhang, Lifang, Ariöz, Candan, Wieslander, Åke, Norling, Birgitta

“…This discrepancy in the subcellular localization of enzyme activity and protein may indicate the presence of either an unknown regulator and/or an as yet unidentified MGS-type enzyme. …”
Get full text
Get full text

Identification of a novel mitochondria-localized LKB1 variant required for the regulation of the oxidative stress response by Tan, Ivan, Xu, Shengli, Huo, Jianxin, Huang, Yuhan, Lim, Hong-Hwa, Lam, Kong-Peng

“…The tumor suppressor Liver Kinase B1 (LKB1) is a multifunctional serine/threonine protein kinase that regulates cell metabolism, polarity, and growth and is associated with Peutz-Jeghers Syndrome and cancer predisposition. …”
Get full text

Supramolecular macrocycle regulated single-atom MoS2@Co catalysts for enhanced oxygen evolution reaction by Cao, Shuai, Wu, Wenzhuo, Liu, Chaozhong, Song, Leqian, Xu, Qun, Zhang, Huuacheng, Zhao, Yanli

Get full text

Design of a thyristor-switched capacitor type voltage regulator of a self-exited induction generation by Oun, Chuan Teck.

“…Voltage regulators are widely used in the transmission network because it is a reliable and feasible solution for maintaining the voltage within a required voltage range. …”
Get full text

Supported Lipid Bilayer Platform To Test Inhibitors of the Membrane Attack Complex: Insights into Biomacromolecular Assembly and Regulation by Yorulmaz, Saziye, Jackman, Joshua Alexander, Hunziker, Walter, Cho, Nam-Joon

“…Taken together, the findings in this study outline a biomimetic approach based on supported lipid bilayers to explore the interactions between complement proteins and inhibitors, thereby offering insight into MAC assembly and regulation.…”
Get full text
Get full text

Regulation of Burkholderia cenocepacia biofilm formation by RpoN and the c-di-GMP effector BerB by Fazli, Mustafa, Rybtke, Morten, Steiner, Elisabeth, Weidel, Elisabeth, Berthelsen, Jens, Groizeleau, Julie, Bin, Wu, Zhi, Boo Zhao, Yaming, Zhang, Kaever, Volkhard, Givskov, Michael, Hartmann, Rolf W., Eberl, Leo, Tolker-Nielsen, Tim

“…Knowledge about the molecular mechanisms that are involved in the regulation of biofilm formation is essential for the development of biofilm‐control measures. …”
Get full text
Get full text

Transphobia as a weapon of war: reporting on Russia’s trans community amidst heightened regulation, censorship and propaganda by Sloane, Wendy

Get full text

Proteomic and metabolomic analyses of the human adult myocardium reveal ventricle-specific regulation in end-stage cardiomyopathies by Hunter, B, Li, M, Parker, BL, Koay, YC, Harney, DJ, Pearson, E, Cao, J, Chen, GT, Guneratne, O, Smyth, GK, Larance, M, O’Sullivan, JF, Lal, S

“…Constituents of gluconeogenesis, glycolysis, lipogenesis, lipolysis, fatty acid catabolism, the citrate cycle and oxidative phosphorylation were down-regulated in the left ventricle, while glycogenesis, pyruvate and ketone metabolism were up-regulated. …”

The need for regulation: permissive governance and disproportionate use of live facial recognition technology by the Metropolitan Police Service by Croker, JT

“…The conclusions reached in this thesis call for appropriate and effective regulation and oversight of police use of LFR to ensure rights are protected from unlawful and disproportionate harm.…”

Effects of hormonal regulation on cell number and cell size in determining fruit size: a mini-review by Siti Khadijah A. Karim, Zamri Zainal, Nik Marzuki Sidik

“…This mini-review discussed the interplay among major plant hormones in regulating cell number production and cell size in horticultural plants. …”
Get full text

A comparison of preterm and full-term infant emotional regulation development through infant-mother affect synchrony by Low, Heather Yee Theng

Subjects: Get full text

Energy level alignment regulation and carrier management in perovskite solar cells with various bandgaps using tailored metal-organic frameworks by Xiao, Bo, Zhang, Wenguang, Xiong, Yuchen, Huang, Yihuai, Huang, Changkai, Qian, Yongxin, Shen, Guibin, Basit, Abdul, Luo, Yubo, Li, Xin, Yang, Junyou

Subjects: “…Energy level alignment regulation…”
Get full text

TPPP acts downstream of RhoA-ROCK-LIMK2 to regulate astral microtubule organization and spindle orientation by Heng, Yi-Wen., Lim, Hong-Hwa., Mina, Theresia., Utomo, Prayudi., Zhong, Shaoping., Lim, Chwee-Teck., Koh, Cheng-Gee

“…Surprisingly, LIMK1 and cofilin are not involved downstream of RhoA and ROCK in the regulation of astral microtubule organization. Instead, we find that LIMK2 acts through TPPP in the regulation of astral microtubule organization, whereas both LIMK1 and LIMK2 affect centrosome focusing. …”
Get full text
Get full text

Regulation of mRNA abundance by polypyrimidine tract-binding protein-controlled alternate 5′ splice site choice by Hamid, Fursham M., Makeyev, Eugene V.

“…More generally, these data expand our understanding of AS regulation and uncover a post-transcriptional strategy ensuring co-expression of a subordinate gene with its master regulator through an AS-NMD tracking mechanism.…”
Get full text
Get full text

A low noise, 1.28µA quiescent regulator with broadband high PSR for micropower sensors by Chan, Pak Kwong, Ong, G. T.

“…An ultra-low power, low-noise, high power supply rejection (PSR) op-ampless regulator is presented in this paper. It uses a native composite power transistor plus a sandwich on-chip native capacitor in the pre-regulator to enhance broadband high PSR performance. …”
Get full text
Get full text
Get full text

Treatment with siRNAs is commonly associated with GPX4 up-regulation and target knockdown-independent sensitization to ferroptosis by von Mässenhausen, Anne, Schlecht, Marlena Nastassja, Beer, Kristina, Maremonti, Francesca, Tonnus, Wulf, Belavgeni, Alexia, Gavali, Shubhangi, Flade, Karolin, Riley, Joel S., Zamora Gonzalez, Nadia, Brucker, Anne, Becker, Jorunn Naila, Tmava, Mirela, Meyer, Claudia, Peitzsch, Mirko, Hugo, Christian, Gembardt, Florian, Angeli, Jose Pedro Friedmann, Bornstein, Stefan R., Tait, Stephen W. G., Linkermann, Andreas

“…In contrast, MAVS mediated a noncanonical signal resulting in a prominent increase in mitochondrial ROS levels, and increase in the BACH1/pNRF2 transcription factor ratio and GPX4 up-regulation, which was associated with a 50% decrease in intracellular glutathione levels. …”
Get full text

Empowering student self-regulated learning and science education through ChatGPT: a pioneering pilot study by Ng, Davy Tsz Kit, Tan, Chee Wei, Leung, Jac Ka Lok

“…In recent years, AI technologies have been developed to promote students' self-regulated learning (SRL) and proactive learning in digital learning environments. …”
Get full text