Loss of Polycystin-1 causes cAMP-dependent switch from tubule to cyst formation by Julia Katharina Scholz, Andre Kraus, Dominik Lüder, Kathrin Skoczynski, Mario Schiffer, Steffen Grampp, Johannes Schödel, Bjoern Buchholz

“…Summary: Autosomal dominant polycystic kidney disease is the most common monogenic disease that causes end-stage renal failure. It primarily results from mutations in the PKD1 gene that encodes for Polycystin-1. …”
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Evaluation of salivary flow rate, pH, and buffer capacities in end-stage renal disease patients versus control – A prospective comparative study by Tanoj Kumar, Jay Kishore, Minti Kumari, Anurag Rai, Shweta Rai, Abhinav Jha

“…Background: Saliva plays a major role in preserving the integrity of oral tissues. Chronic renal failure patient undergoes many oral and salivary changes for which they require special oral health care. …”
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Severe Acute Interstitial Nephritis, Dermatitis, and Hemolytic Anemia due to Polyparasitic Infection in an Immunocompetent Male Patient by Sanda Mrabet, Wiem Romdhane, Asma Fradi, Raja Boukadida, Awatef Azzabi, Yosra Guedri, Wissal Sahtout, Narjess BenAicha, Nihed Abdessayed, Moncef Mokni, Dorsaf Zellama, Abdellatif Achour

“…Acute interstitial nephritis (AIN) is a relevant cause of acute renal failure. Drugs are the predominant cause, followed by infections and idiopathic lesions. …”
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Intra-aortic balloon pump use does not affect the renal function in patients undergoing off pump coronary artery bypass surgery by Muniraju Geetha, Pandey Sourabh, Chakravarthy Murali, Krishnamoorthy Jayaprakash, Narayan Sandeep, Jawali Vivek

“…At times, in patients with renal failure and low cardiac output status, one may face the dilemma if the use of IABP is safe. …”
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A Step Closer to the “Fourth 90”: A Practical Narrative Review of Diagnosis and Management of Nutritional Issues of People Living with HIV by Davide Fiore Bavaro, Paola Laghetti, Mariacristina Poliseno, Nicolò De Gennaro, Francesco Di Gennaro, Annalisa Saracino

“…To achieve an early diagnosis of these comorbidities, clinicians have at their disposal algorithms such as the Framingham Score to assess cardiovascular risk; transient elastography and liver biopsy to detect NAFLD and NASH; and markers such as the oral glucose tolerance test and GFR to identify glucose impairment and renal failure, respectively. Furthermore, maintenance of ideal body weight is the goal for reducing cardiovascular risk and to improve diabetes, steatosis and fibrosis; while Mediterranean and low-carbohydrate diets are the dietetic approaches proposed for cardioprotective effects and for glycemic control, respectively. …”
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Application of nanotechnology in the treatment of glomerulonephritis: current status and future perspectives by He-Qin Zhan, Xiaoxun Zhang, Xu-Lin Chen, Liang Cheng, Xianwen Wang

“…Abstract Glomerulonephritis (GN) is the most common cause of end-stage renal failure worldwide; in most cases, it cannot be cured and can only delay the progression of the disease. …”
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The Renal Manifestations of SARS-CoV-2: A Guide for Family Physicians by Austin P. Morrissey, Nagla Elzinad, Chris El Hayek, Saran Lotfollahzadeh, Vipul C. Chitalia

“…In COVID-19 patients, renal failure contributes to morbidity and mortality, and its early detection and timely management are critical to minimize such untoward and irreversible complications. …”
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Dexmedetomidine improves ultrastructural view of renal damage and biochemical parameters during an experimental inflammatory bowel disease by Gulay Erdogan Kayhan, Basak Kayhan, Mehmet Gul, Zeynal Mete Karaca

“…IBD frequently cause reduction in renal function and renal failure. Since perioperative anesthesia and postoperative conditions in intensive care can cause acute kidney injury and reduction on renal function; deciding on a sedative and anesthetic agent without side effects would reduce IBD caused renal damage. …”
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4182 Use of Machine Learning for Surgical Outcomes Research: what are the clinical implications? by Priscila Rodrigues Armijo, Sindhura Bonthu, Alicia Schiller, Qiuming Zhu, Tiffany Tanner

“…Conversely, the use of machine learning revealed that preoperative weight loss, preexistent chest heart failure, renal failure or perivascular disease were strongly associated with 30-day mortality. …”
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Rapid diagnosis of membranous nephropathy based on serum and urine Raman spectroscopy combined with deep learning methods by Xueqin Zhang, Xue Song, Wenjing Li, Cheng Chen, Miriban Wusiman, Li Zhang, Jiahui Zhang, Jinyu Lu, Chen Lu, Xiaoyi Lv

“…Abstract Membranous nephropathy is the main cause of nephrotic syndrome, which has an insidious onset and may progress to end-stage renal disease with a high mortality rate, such as renal failure and uremia. At present, the diagnosis of membranous nephropathy mainly relies on the clinical manifestations of patients and pathological examination of kidney biopsy, which are expensive, time-consuming, and have certain chance and other disadvantages. …”
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Characteristics and treatments of patients with significantly elevated creatine kinase levels induced by seizures: Case report and literature review by Kai Wang, Jinwei Yang, Wenhao Xu, Lei Wang, Yu Wang

“…No patient developed renal failure or required continuous renal replacement therapy. …”
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Experience of heart transplantation with an extended cold ischemic time of donor heart by A. V. Fomichev, D. S. Khvan, H. A. Agaeva, M. O. Zhulkov, D. V. Doronin, A. M. Chernyavsky

“…There was no difference between the groups in the acute rejection rate, the need for inotropic agents, mechanical circulatory support, and cardiac pacing, as well as the incidence of postoperative renal failure and infectious complications.Conclusion. …”
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Epidemiological Study of the Prevalence of Death in Older Adults Receiving Home Treatment Services in Tehran Using ICD-10, 2012-2016 by Kamran Irandoust, Morad Esmaiil Zali, Arash Parvari, Faroogh Na'emani

“…Results: The main causes of death were as follows: respiratory diseases (acute respiratory failure=65.86%), gastrointestinal diseases (liver cirrhosis= 47.5%), cardiovascular diseases (hypotension= 53.33%), neurological diseases (stroke= 100%), parasitic infectious diseases (septic shock= 85.48%), cancer (liver cancer= 84.62%), endocrine, nutritional and metabolic diseases (hypoglycemic coma= 66.7%), and urogenital diseases (renal failure= 97.85%). Conclusion: In population studied cardiovascular disease, respiratory and infectious-parasitic diseases were the main causes of death. …”
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Recent Advances of Animal Models of Renal Interstitial Fibrosis by LAI Can, LI Lele, HU Tala, MENG Yan

“…Whether it is chronic kidney disease or acute kidney injury that cannot be fully recovered, the progression process mostly enters end-stage renal failure after renal interstitial fibrosis. The animal model of renal interstitial fibrosis is an important research tool for exploring the pathogenesis of renal interstitial fibrosis and new diagnostic and treatment methods. …”
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Infectious anastomotic pseudoaneurysm complicating renal allograft: case report and review of literature by Chung MMT, Chan YC, Law Y, Cheng SW

“…We report a 45-year-old man with hypertension, diabetes mellitus and end stage renal failure, who had a renal transplant anastomosed to the right external iliac artery and vein. …”
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National Epidemiological Study about Hepatitis C Virus Infection among Dialysis Patients by Meriam Hajji, Samia Barbouch, Rihab Manaa, Khaoula Ajimi, Fethi Ben Ben Hamida, Rym Goucha, Imen Gorsane, Taieb Ben Abdallah

“…This is a nationwide multicenter observational study including all dialysis patients regardless of age and gender. Those with acute renal failure and vacationers were excluded from the study. …”
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Study effect of methanolic extract of Peganum Harmala and Harmine on Kidney tissue damage of diabetes mellitus in male Wistar rats by Forough Kajbaf, Shahrbanoo Oryan, Ramesh Ahmadi, Akram Eidi

“…Introduction: The dangerous side effects of diabetes are diabetic nephropathy, which has a relatively high prevalence in diabetic patients and causes renal failure. Investigating the process of destruction and the mechanisms that prevent it, in order to reduce the tissue damage, especially with the treatment of plants, can be a significant issue. …”
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The association between serum glucose to potassium ratio on admission and short-term mortality in ischemic stroke patients by Yuzhao Lu, Xin Ma, Xiaobing Zhou, Yang Wang

“…The results of multivariable regression analysis showed that GPR at baseline was positively associated with the 30-day mortality (OR 2.01, 95% CI 1.12, 3.61) after adjusting for potential confounders (age, gender, department, serum sodium, serum albumin, serum-magnesium, hypertension, heart failure, chronic renal failure, and pneumonia). When GPR was translated to a categorical variable, the ORs and 95% CIs in the tertiles 2 to 3 versus the tertile 1 were 1.24 (0.60, 2.56) and 2.15 (1.09, 4.24), respectively (P for trend = 0.0188). …”
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Enhanced Recovery after Vascular Surgery by Milena D. Stojanovic, Danica Z. Markovic, Anita Z. Vukovic, Vesna D. Dinic, Aleksandar N. Nikolic, Tijana G. Maricic, Radmilo J. Janković, Radmilo J. Janković

“…Over the past decades, special attention was directed to the postoperative management in vascular surgery, especially after major vascular surgery because of the great risk of multiorgan failure, such as: respiratory failure, myocardial infarction, hemodynamic instability, coagulopathy, renal failure, neurological disorders, and intra-abdominal complications. …”
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The Role of Mitochondria in Acute Kidney Injury and Chronic Kidney Disease and Its Therapeutic Potential by Xiaoqin Zhang, Ewud Agborbesong, Xiaogang Li

“…Persistent dysregulation of mitochondrial homeostasis in AKI and CKD affects diverse cellular pathways, leading to an increase in renal microvascular loss, oxidative stress, apoptosis, and eventually renal failure. It is important to understand the cellular and molecular events that govern mitochondria functions and pathophysiology in AKI and CKD, which should facilitate the development of novel therapeutic strategies. …”
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