The Rationale of Complement Blockade of the MCP_ggaac Haplotype following Atypical Hemolytic Uremic Syndrome of Three Southeastern European Countries with a Literature Re... by Daniel Turudic, Danka Pokrajac, Velibor Tasic, Dino Kasumovic, Zoltan Prohaszka, Danko Milosevic

“…If complement inhibition is not applied within 4–5 relapses, proteinuria and chronic renal failure will eventually occur.…”
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Iron Exchange and Prediction of Multiple Organ Dysfunctions in Sepsis by E. N. Barkova, Ye. V. Zhdanova, V. V. Kuznetsov, L. F. Balabanova, O. G. Sivkov

“…With the poor course of sepsis and its complication as MOD, considerable rises in Fe2+, MDA, and MSM mesors were followed by their rhythm inversion and diminished MSM excretion due to progressive acute renal failure.Conclusion. The desynchronized exchange of iron was found to be due to the intensive increase in its fraction that triggers LPO and membrane destructive processes. …”
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Acute kidney injury due to myoglobin cast nephropathy in the setting of coronavirus disease 2019-mediated rhabdomyolysis: a case report by Jessica J. Tuan, Onyema Ogbuagu, Deepika Kumar, Frederick Altice, Margaret Fikrig

“…His hospital course was complicated by acute kidney injury and, upon workup of his renal failure, was diagnosed with myoglobin cast nephropathy due to coronavirus disease 2019-mediated rhabdomyolysis. …”
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Outcomes of Different Immunosuppressive Regimen in Adult Biopsy Proven Idiopathic Focal Segmental Glomerulosclerosis: A Retrospective Analysis at a Single Center by Ruqaya Qureshi, Kiran Nasir, Salman Imtiaz, Murtaza F Dhrolia, Aasim Ahmad, Bina Salman

“…The degree of TIF and renal failure has strong influence on the course of the disease.…”
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Microbiome in Chronic Kidney Disease by Theodoros Tourountzis, Georgios Lioulios, Asimina Fylaktou, Eleni Moysidou, Aikaterini Papagianni, Maria Stangou

“…Therefore, potentially noxious microbial uremic toxins, which have predominantly renal clearance, including p-cresyl sulfate, indoxyl sulfate and N-oxide of trimethylamine [Trimethylamine-N-Oxide (TMAO)], accumulate in human’s body, and are responsible not only for the clinical implications of CKD, but also for the progression of renal failure itself. Certain changes in gut microbiome are observed in patients with end stage renal disease (ESRD), either when undergoing hemodialysis or after kidney transplantation. …”
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Sodium Tungstate (NaW) Decreases Reactive Oxygen Species (ROS) Production in Cells: New Cellular Antioxidant by Alejandro J. Yañez, Karen Jaramillo, Camila Blaña, Rafael A. Burgos, Adolfo Isla, Pamela Silva, Marcelo Aguilar

“…Diabetic nephropathy (DN) is the leading cause of end-stage renal failure worldwide. Hyperglycemia generates reactive oxygen species (ROS), contributing to diabetic complications, especially in DN. …”
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Prevalence and Spectrum of Albuminuria among Type 2 Diabetic Patients in a Tertiary Health-care Facility in Southern Nigeria by Beniboba Jenewari Eleki, Pedro C Emem-Chioma

“…Background: Diabetic nephropathy (DN) is a life-threatening microvascular complication often leading to progressive renal failure and death. Microalbuminuria is an early marker of DN and a major risk factor for endothelial dysfunction. …”
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Drug Utilization Evaluation of Imipenem in Patients Undergoing Bone Marrow Transplantation by Elnaz Sakhaiyan, Molouk Hadjibabaie, Kheirollah Gholami, Fanak Fahimi, Ahmad Reza Shamshiri, Kamran Alimoghaddam, Masoud Iravani, Seyed Asad-o-allah Mousavi, Ardeshir Ghavamzadeh

“…Twenty- two (35.9%) patients needed dosage adjustments due to low weight or renal failure, but no action in this regard was taken. …”
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Special conditions in the treatment of hemorrhoidal disease. The advantages of THD-RAR in the treatment of hemorrhoidal disease in these situations by Romica Mehic, Veronica Indreica, Vasilica Marcu, Mircea Beuran, Alexandru Laurentiu Chiotoroiu

“…We have studied the articles published in the period 1990-2020, which referred to special condition in patients with hemorrhoidal disease (young, elderly, pregnant woman, coagulation disorders, immunosuppressive states, colon inflammatory diseases, cirrhosis, renal failure, neurological diseases, associated perianal diseases). …”
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Kidney replacement therapy: profile of patients in a teaching hospital by Taís Pagliuco Barbosa, João César Jacon, Maria Cláudia Parro, Adriani Izabel de Souza Moraes, Tatiane Veteri Coneglian, Francielly Aparecida Correa Iembo

“…Objective: to evaluate the quality of life of patients with chronic renal failure during hemodialysis and differences in relation to sex. …”
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<i>Escherichia coli</i> Shiga Toxins and Gut Microbiota Interactions by Kyung-Soo Lee, Yu-Jin Jeong, Moo-Seung Lee

“…This, in turn, may result in potentially lethal complications, such as hemolytic uremic syndrome (HUS), which is characterized by thrombocytopenia, acute renal failure, and neurological abnormalities. Both species of bacteria produce Shiga toxins (Stxs), a phage-encoded exotoxin inhibiting protein synthesis in host cells that are primarily responsible for bacterial virulence. …”
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Pharmacokinetic Properties of the Nephrotoxin Orellanine in Rats by Deman Najar, Börje Haraldsson, Annika Thorsell, Carina Sihlbom, Jenny Nyström, Kerstin Ebefors

“…Accidental intake of this substance may cause renal failure. Orellanine is specific for proximal tubular cells and could, therefore, potentially be used as treatment for metastatic renal cancer, which originates from these cells. …”
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Consideration of Intestinal Failure in Cases of De-Adaptation of Short Bowel Syndrome: A Case Report and Descriptive Review by Tasuku Kato, Yasuhisa Nakano, Fumiko Yamane, Ryuichi Ohta, Chiaki Sano

“…Therefore, we stress the importance of re-emphasizing the concept of ”intestinal failure” in everyday practice, as well as other organ-related conditions such as cardiac or renal failure, as this may lead to a better understanding of the pathogenesis of malnutrition and diarrhoea in elderly patients.…”
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Severe colchicine poisoning treated successfully with kidney replacement therapy and plasmapheresis: a case report by D. H. Schaffer, D. L. Overbeek, T. B. Erickson, E. W. Boyer, C. Goldfine, S. A. Muhsin, P. R. Chai

“…The patient’s course was complicated by multiorgan failure including coagulopathy, respiratory failure, neuropathy, renal failure, pancytopenia, and heart failure. He was discharged to inpatient rehabilitation on hospital day 24. …”
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Role of nurses in the initiation and the monitoring of Lithium by M. Moalla, A. Larnaout, D. Skhiri, R. Lansari, N. Staali, W. Melki

“…The vast majority of subject (85%) said that lithium’s dosage must be individualized and adaptable to each patient throughout a specific blood test. 90% recognized renal failure as the most common contraindication of lithium. …”
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Two cases of Ramsay-Hunt syndrome following varicella zoster viral meningitis in young immunocompetent men: case reports by Yun Su Hwang, Young Seo Kim, Byoung-Soo Shin, Hyun Goo Kang

“…VZV infection may invade the central nervous system (CNS) and cause meningitis or encephalitis, which are more likely to occur in patients with chronic diseases such as diabetes and chronic renal failure. However, cases with VZV-induced concurrent RHS and CNS infections are rare. …”
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A prospective study of brain natriuretic peptide levels in three subgroups: Stroke with hypertension, stroke without hypertension, and hypertension alone by Cakir Zeynep, Saritas Ayhan, Emet Mucahit, Aslan Sahin, Akoz Ayhan, Gundogdu Fuat

“…Patients with congestive heart failure, chronic cor pulmonale, severe valvular heart disease, chronic renal failure, liver insufficiency, diabetes mellitus, atrial fibrillation, and those with a history of stroke were excluded from the study since these diseases can affect the plasma BNP levels. …”
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Increased Cardiac Troponin-T in Patients without Myocardial Infarction by M. Ya. Krasnoselsky, Ye. V. Koshkina, N. M, Fedorovsky, Ye. V. Goryacheva, A. A. Polupan, A. A. Arefyev, M. Z. Bratanova

“…The definitive diagnosis of AMI was established only in 29 (40.3%) patients; the remaining 43 patients were diagnosed as having the following diseases: sepsis (n=21), cancer (n=10), diabetic nephropathy with chronic renal failure (n=6), cerebral infarction (n=4), and B12-deficiency anemia (n=2). …”
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The first case of IgG4-related disease in Italy by Davide Rolla, Diego Bellino, Giancarlo Peloso, Maria Pia Rastaldi, Paola Simonini, Jean Louis Ravetti

“…After one year, the patient began to exhibit signs of "sicca syndrome", and at the same time, he demonstrated progressive renal failure. Immunological tests showed hypocomplementemia, and the renal biopsy specimen demonstrated interstitial inflammation, in which infiltrate was composed of lymphocytes, while infiltrating plasma cells showed immunoreactivity to IgG4. …”
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FEATURES OF HEART LESION IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS (LITERATURE REVIEW) by V. Dubovyk, V.E. Kondratiuk

“…Mortality because of SLE is three times higher than in the population, while among its causes, CVS ranks third after infections and renal failure. The results of numerous studies about the features of the clinical picture, diagnosis and treatment of SLE patients with primary lesions of the heart are presented and analyzed. …”
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