Platelet to lymphocyte ratio: can it be an early economical mortality predictor of AKI patients? by Arnab Purkayastha, Amit Kalwar, Zakia Firdaus, Bhaskar Kanti Nath, Prithwiraj Bhattacharjee

“…The potential long-term progression to chronic kidney disease (CKD) and renal failure, as well as the acute use of health care resources associated with acute kidney injury (AKI), impose enormous costs on society. …”
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Evaluation of Clinical Features and Prognosis in COVID-19 Patients with Hypertension: A Single-center Retrospective Observational Study by Gülay OKAY, Bülent DURDU, Yasemin AKKOYUNLU, Sibel BÖLÜKÇÜ, Asiye Bahar KAÇMAZ, Bilge SÜMBÜL, Hatice Dilara KARAKUŞ, Meliha Meriç KOÇ

“…Hypertensive patients were older (64.6±11.5 and 47.2±13.9) (p<0.001), had higher diabetes mellitus rates (41.7% and 11.5%, p<0.001) and more complicated with chronic renal failure (16.5% vs. 2.5%, p<0.001).While 56.1% of patients were desaturated in the hypertensive group (SaPO2 <93%), this rate was 32.3% in the group without hypertension (p<0.001). …”
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Results of kidney transplantation from suboptimal donors to recipients of the older age group by B. Z. Khubutiya, M. Sh. Khubutiya, A. K. Evseev, A. V. Babkina

“…Among the growing number of patients with chronic renal failure who need dialysis therapy or kidney transplantation, a significant proportion are people over 60 years old, making from 30 to 45% of all patients who need dialysis, according to various sources. …”
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Characteristics and Lethality of a Novel Recombinant  Dermonecrotic Venom Phospholipase D from  Hemiscorpius lepturus by Elham Torabi, Mahdi Behdani, Mohammad Hosseininejad Chafi, Reza Moazzami, Jean‐Marc Sabatier, Vahid Khalaj, Delavar Shahbazzadeh, Kamran Pooshang Bagheri

“…The clinical signs of H. lepturus envenomation are remarkably similar to those reported for brown spiders, including dermonecrosis, hematuria, renal failure and even death. The lethality and toxicity of brown spiders’ venom have been attributed to its phospholipase D activity. …”
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Cell Biological Responses after Shiga Toxin-1 Exposure to Primary Human Glomerular Microvascular Endothelial Cells from Pediatric and Adult Origin by Wouter J. C. Feitz, Petra A. van Setten, Thea J. A. M. van der Velden, Christoph Licht, Lambert P. J. W. van den Heuvel, Nicole C. A. J. van de Kar

“…Hemolytic uremic syndrome (HUS) is characterized by a triad of symptoms consisting of hemolytic anemia, thrombocytopenia and acute renal failure. The most common form of HUS is caused by an infection with Shiga toxin (Stx) producing <i>Escherichia coli</i> bacteria (STEC-HUS), and the kidneys are the major organs affected. …”
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Everolimus Reduces Cancer Incidence and Improves Patient and Graft Survival Rates after Kidney Transplantation: A Multi-Center Study by Ryoichi Imamura, Ryo Tanaka, Ayumu Taniguchi, Shigeaki Nakazawa, Taigo Kato, Kazuaki Yamanaka, Tomoko Namba-Hamano, Yoichi Kakuta, Toyofumi Abe, Koichi Tsutahara, Tetsuya Takao, Hidefumi Kishikawa, Norio Nonomura

“…Kidney transplantation can prevent renal failure and associated complications in patients with end-stage renal disease. …”
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Hospital characteristics and perioperative complications of Hispanic patients following reverse shoulder arthroplasty—a large database study by Nikit Venishetty, Garrett Sohn, Ivy Nguyen, Meesha Trivedi, Varatharaj Mounasamy, Senthil Sambandam

“…In looking at postoperative complications, Hispanic patients had increased incidences of acute renal failure (Hispanics: 3.1%, control group: 1.1%, P = 0.03) and blood loss anemia (Hispanics: 12.7%, control group: 10.9%, P = 0.03). …”
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Risk factors and lethality associated with Candidemia in severe COVID-19 patients by Zehra Beştepe Dursun, Hilal Sipahioğlu, Recep Civan Yüksel, Hafize Sav, Ilhami Çelik

“…The number of patients with diabetes mellitus and chronic renal failure was higher in the candidemia group. In the candidemia group, the duration of ICU stay of patients, the 30-day mortality rate, mechanical ventilation therapy, and systemic corticosteroids (Prednisone) usage were significantly higher in candidemia patients. …”
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Cardiac outcomes after successful kidney transplantation by Ahmed Hassan, Hala I Mohamed, Yasser A Hendy, Hala M Allam, Mohamed K Mohamed

“…It is the most acceptable treatment modality for the patients with ESRD, which improves some complications of renal failure such as chronic uremia and volume overload. …”
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Apelin: A potential novel serum biomarker for early detection of diabetic nephropathy in patients with type 2 diabetes by Muhammed Mustafa Demirpençe, Hamiyet Yilmaz, Ayfer Çolak, Baris Onder Pamuk, İnanç Karakoyun, Banu Basok

“…INTRODUCTION[|]Diabetic nephropathy (DN) is the major cause of chronic renal failure, and proteinuria is an independent risk factor for the end stage renal disease. …”
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Clinical Care Team’s Guide for Awareness on Risk Assessment of Eltrombopag Complicating Acute Kidney Injury in Relapsed Immune Thrombocytopenic Patients: A Case Report by Eman Mostafa Hamed, Mohamed Hussein Meabed, Ahmed R. N. Ibrahim, Ahmed M. Khalaf, Doaa Mohamed El Demerdash, Marwa O. Elgendy, Haitham Saeed, Tamer M. Mahmoud, Heba F. Salem, Hoda Rabea

“…A sudden increase in serum creatinine to 6.7 mg/dL and metabolic acidosis occurred after eight weeks of Eltrombopag. The patient’s renal failure had worsened, proteinuria was detected, and emergency hemodialysis was initiated. …”
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Acute fulminant hepatic failure due to colchicine – a rare manifestation of Gloriosa superba poisoning. by ANANDHI D, KNJ Prakash Raju, BALAJI BDS, Anuusha SS

“…Phase 1:(2-24 hours) early gastrointestinal symptoms mimicking gastroenteritis, volume depletion, hypotension, peripheral leucocytosis; Phase 2:(24 to 72 hours) mental status changes, oliguric renal failure, hematopoietic problems, electrolyte imbalance, acid-base disturbance, shock, bone marrow suppression, liver failure, ARDS, arrhythmias, cardiovascular collapse, encephalopathy and neuromuscular involvement; and Phase 3:(1-3 weeks) Recovery typically occurs within few weeks of ingestion but with rebound leucocytosis and alopecia. …”
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Effect of trans-sodium crocetinate on contrast-induced cytotoxicity in HEK-293 cells by Fatemeh Rajabian, Soghra Mehri, BiBi Marjan Razavi, Abolfazl Khajavirad, Mahboobeh Ghasemzadeh Rahbardar, Hossein Hosseinzadeh

“…This complication is the third cause of renal failure after hospital treatment. The current study is designed to investigate the possible protective effect of trans-sodium crocetinate (TSC), derived from carotenoid crocetin, against sodium amidotrizoate/meglumine amidotrizoate (SAMA) induced cytotoxicity in HEK-293 cells.Materials and Methods: HEK-293 cells were incubated with different concentrations of TSC (1, 2.5, 5, 10, 25, and 50 µM, for 48 hr) and then SAMA (7 mgI/ml, for 24 hr) was added. …”
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Medication-Wide Association Study Using Electronic Health Record Data of Prescription Medication Exposure and Multifetal Pregnancies: Retrospective Study by Lena Davidson, Silvia P Canelón, Mary Regina Boland

“… BackgroundMedication-wide association studies (MWAS) have been applied to assess the risk of individual prescription use and a wide range of health outcomes, including cancer, acute myocardial infarction, acute liver failure, acute renal failure, and upper gastrointestinal ulcers. Current literature on the use of preconception and periconception medication and its association with the risk of multiple gestation pregnancies (eg, monozygotic and dizygotic) is largely based on assisted reproductive technology (ART) cohorts. …”
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Safety and efficacy of colchicine in crystal-induced arthritis flare in 54 patients with severe chronic kidney disease by Renaud Felten, Bruno Michel, Bénédicte Gourieux, Marion Fourtage, Johanna Bausson, Nicolas Keller, Jean-Jacques Von Hunolstein, Matthieu Sacrez

“…The main reason for hospitalisation was heart failure (31.5%), acute renal failure (22.2%), infection (18.5%) or an acute joint episode (9.3%). …”
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Assessment of the Necessity of Osteoporosis Treatment for Patients with Low Bone Density in Diffuse Idiopathic Skeletal Hyperostosis by Mitsuru Furukawa, Kunimasa Okuyama, Ken Ninomiya, Takeshi Miyamoto, Yoshiyuki Yato

“…Group A (T-score−1) and B (T-score>−1) data were adjusted for confounding factors and compared for differences in age, body weight, maximum number of vertebral bodies with bony bridges between adjacent vertebrae (max VB), and previous history (hypertension, malignant tumors, diabetes mellitus, cardiac diseases, chronic renal failure, and spinal fractures). In Group A, multiple linear regression was used to investigate relationships among max VB, femur bone mineral density (BMD), total type I procollagen N-terminal propeptide (P1NP), and tartrate-resistant acid phosphatase 5b (TRACP-5b). …”
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e-Health: A Future Solution for Optimized Management of Elderly Patients. GER-e-TEC™ Project by Abrar-Ahmad Zulfiqar, Noël Lorenzo-Villalba, Oumair-Ahmad Zulfiqar, Mohamed Hajjam, Quentin Courbon, Lucie Esteoulle, Bernard Geny, Samy Talha, Dominique Letourneau, Jawad Hajjam, Sylvie Erve, Amir Hajjam El Hassani, Emmanuel Andres

“…<b>Background:</b> Elderly residents in nursing homes have multiple comorbidities (including cognitive and psycho-behavioral pathologies, malnutrition, heart failure, diabetes, chronic obstructive pulmonary disease, and renal failure) and use multiple medications. <b>Methods:</b> The GER-e-TEC project aims to provide these fragile and complex patients with telemedicine tools, more specifically telemonitoring, backed by a well-defined and personalized protocol. …”
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Daily dose of metformin caused acute kidney injury with lactic acidosis: a case report by Maho Ariga, Junichiro Hagita, Midori Soda, Yasuhisa Oida, Hitomi Teramachi, Kiyoyuki Kitaichi

“…Here we report a case of a Japanese patient taking metformin who experienced severe acute renal failure accompanied with significantly elevated metformin plasma concentrations and signs of lactic acidosis. …”
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Reducing GEF-H1 Expression Inhibits Renal Cyst Formation, Inflammation, and Fibrosis via RhoA Signaling in Nephronophthisis by Qiulei Hu, Jiayong Lai, Huamu Chen, Yong Cai, Zhihui Yue, Hongrong Lin, Liangzhong Sun

“…Nephronophthisis (NPHP) is the most prevalent monogenic disease leading to end-stage renal failure in childhood. RhoA activation is involved in NPHP pathogenesis. …”
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The Impact of Chronic Liver Disease on Postoperative Outcomes and Resource Utilization by Joseph B. Oliver, Aziz M. Merchant, Baburao Koneru

“…Complications specific to CLD were increased based on MELD specifically coma (OR 1.6, 0.9–2.9 for Low MELD, 2.2, 1.5–3.2 for High MELD), renal failure (OR 1.4, 1.1–1.8 and 2.4, 2.0–2.9), and bleeding (OR 1.7, 1.5–1.9 and 2.0, 1.8–2.3). …”
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