Long-term outcomes of urinary tract infection (UTI) in childhood: The LUCI study by Kathryn Hughes, Rebecca Cannings-John, Hywel Jones, Fiona Lugg-Widger, Mandy Lau, Shantini Paranjothy, Nick Francis, Alastair Hay, Christopher Butler, Judith Van der Voort, Kerenza Hood

“…The primary outcome was renal scarring and secondary outcomes included hypertension, chronic kidney disease and renal failure. The primary analysis used multinomial regression and time to event models. …”
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COVID-19 patients hospitalized after the fourth wave of the pandemic period in Vietnam: Clinical, laboratory, therapeutic features, and clinical outcomes by Trinh Cong Dien, Le Van Nam, Pham Ngoc Thach, Le Van Duyet

“…Patients died mostly as a result of co-morbidities, low SpO2, lung injury, and complications such as bacterial + fungal pneumonia (83.9%), ARDS (83.9%), bacteremia (56.5%), injury acute renal failure (27.4%), and coagulopathy (12.9%). Conclusion: Severe and critical COVID-19 patients frequently have several comorbidities, multiple lung lesions along with a variety of clinical signs. …”
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MicroRNA-10 Family Promotes the Epithelial-to-Mesenchymal Transition in Renal Fibrosis by the PTEN/Akt Pathway by Chaokun Wang, Yichen Shuai, Chuan Zhao, Fengrui Yang, Weilian Su, Zhifen Ning, Guoxia Li

“…Renal fibrosis (RF) is a common reason for renal failure, and epithelial-mesenchymal transition (EMT) is a vital mechanism that promotes the development of RF. …”
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Risk factors for perioperative blood transfusion in patients undergoing total laparoscopic hysterectomy by Xianghua Cao, Xueliang Liu, Xingxing Zhang, Kefang Zhang, Chuan Chen, Qinfeng Yang, Jian Wang, Xueping Li, Ling Wei

“…Perioperative blood transfusion after TLH was associated with chronic blood loss anemia, deficiency anemia, coagulopathy, congestive heart failure, fluid and electrolyte disorders, renal failure, metastatic cancer, sepsis, weight loss, deep vein thrombosis, gastrointestinal hemorrhage, shock, acute myocardial infarction, and pneumonia, stroke, hemorrhage, pulmonary embolism, and disease of the genitourinary system. …”
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Hydrogen gas improves left ventricular hypertrophy in Dahl rat of salt-sensitive hypertension by Hiroki Matsuoka, Seiko Miyata, Nozomi Okumura, Takuya Watanabe, Katsunori Hashimoto, Miki Nagahara, Kazuko Kato, Sayaka Sobue, Kozue Takeda, Masatoshi Ichihara, Takashi Iwamoto, Akiko Noda

“…Purpose: Hypertension is an important risk factor for death resulting from stroke, myocardial infarction, and end-stage renal failure. Hydrogen (H2) gas protects against many diseases, including ischemia-reperfusion injury and stroke. …”
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Chaihu-Longgu-Muli decoction improves sleep disorders by restoring orexin-A function in CKD mice by Xin-li Cao, Xue-mei Peng, Gong-bo Li, Wei-sen Ding, Kai-zhen Wang, Xiao-lei Wang, Yan-ying Xiong, Wei-jian Xiong, Fan Li, Min Song

“…While it has been used extensively as a therapeutic treatment for neuropsychiatric disorders, such as insomnia, anxiety and dementia, its mechanisms remain unclear.MethodsIn order to analyze the therapeutic mechanism of CLMD in chronic renal failure and insomnia, An adenine diet-induced chronic kidney disease (CKD) model was established in mice, Furthermore, we analyzed the impact of CLMD on sleep behavior and cognitive function in CKD mice, as well as the production of insomnia related regulatory proteins and inflammatory factors.ResultsCLMD significantly improved circadian rhythm and sleep disturbance in CKD mice. …”
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Comparative Effectiveness of Generic Atorvastatin and Lipitor® in Patients Hospitalized with an Acute Coronary Syndrome by Cynthia A. Jackevicius, Jack V. Tu, Harlan M. Krumholz, Peter C. Austin, Joseph S. Ross, Therese A. Stukel, Maria Koh, Alice Chong, Dennis T. Ko

“…Secondary outcomes included hospitalization for heart failure, stroke, new‐onset diabetes, rhabdomyolysis, and renal failure. In the 7863 propensity‐matched pairs (15 726 patients), mean age was 76.9 years, 56.3% were male, 87.6% had myocardial infarction, and all patients had complete follow‐up. …”
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VIPoma: a rare cause of diarrhea. A case report by Sara María Sánchez-Salazar, Santiago Torres-Alzate, Viviana Marcela Muñoz-Cortés, Carlos Alfonso Builes-Barrera, Jorge Iván Gutiérrez-Montoya, Alejandro Román-González

“…Case presentation: A 61-year-old woman visited the emergency department of a tertiary care hospital in Medellín, Colombia, due to chronic diarrhea (7 months) that led to dehydration, renal failure, metabolic acidosis, and hypokalemia. As a result, a treatment based on loperamide, intravenous fluids and broad-spectrum antibiotics was started. …”
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Renoprotective Impacts of <i>Inonotus obliquus</i> Ethanol-Ethyl Acetate Extract on Combined Streptozotocin and Unilateral Nephrectomy-Induced Diabetic Nephropathy in Mice by Kuang-Hsing Chiang, Yi-Chun Chiu, Noi Yar, Yu-Chun Chen, Chia-Hui Cheng, Yi-Chien Liu, Chia-Yu Chang, Jiunn-Jye Chuu

“…Medication options to stop or slow the progression of chronic renal disease (CKD) are limited, and patients with DN remain at a high risk of developing renal failure. <i>Inonotus obliquus</i> extracts (IOEs) of Chaga mushroom have been shown to have anti-glycemic, anti-hyperlipidemia, antioxidant, and anti-inflammatory effects against diabetes. …”
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Prevalence and outcomes of atrial fibrillation in patients suffering prostate cancer: a national analysis in the United States by Zhemin Pan, Xiao Xu, Xi Xu, Shengyong Wu, Zhensheng Zhang, Suxuan Liu, Zhijian Liu, Boxiang Tu, Chenxin Chen, Yingyi Qin, Jia He, Jia He

“…AF was associated with adverse clinical outcomes, such as in-hospital mortality, congestive heart failure, pulmonary circulation disorders, renal failure, fluid and electrolyte disorders, cardiogenic shock, higher total cost, and longer length of hospital stay.ConclusionsThe prevalence of AF among inpatients with PC increased from 2008 to 2017. …”
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Prevalence and factors associated with hyperphosphatemia in continuous ambulatory peritoneal dialysis patients: A cross-sectional study by Xiaojing Yin, Xiaojing Yin, Fan Zhang, Yan Shi

“…However, phosphorus management still has many challenges.ObjectiveThis study aimed to investigate the prevalence and factors of hyperphosphatemia among continuous ambulatory peritoneal dialysis patients in a tertiary public hospital in Shanghai, China.MethodsThe single-center cross-sectional study recruited end-stage renal failure patients who received continuous ambulatory peritoneal dialysis (CAPD) for at least 3 months. …”
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Spectrum and prevalence of renal dysfunction among heart failure patients attending tertiary care hospital: first report from Somalia by Mohamed Osman Omar Jeele, Ahmed Abdirahman Hussein, Mohamed Abdullahi Mohamud, Abdulkamil Abdullahi Adani, Mohamed Farah Yusuf Mohamud

“…Males were 2 and half times more likely to develop renal failure than females. Conclusions we found that the prevalence of renal dysfunction in heart failure patients is 20.6%. …”
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Diastolic Dysfunction in Asymptomatic Type 2 Diabetic Patients Having Preserved Systolic Function by Mir Waqas Baloch, Imran Zameer, Kashif Khan, Zoha Majeed, Muhammad Asad, Muhammad Asad, Khurrum Abbass, Ayesha Sana

“…We excluded patients with valvular heart disease, ischemia, congestive heart failure, cardiomyopathy of any aetiology, renal failure, pulmonary illness, anemia, hemoglobinopathies, prior myocardial infarctions in any region, smokers,and hypertension. …”
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A case of severe hyperparathyroidism in clinical practice. Case report by Elena V. Biryukova, Mikhail V. Shinkin, Svetlana V. Podachina, Ilia Yu. Feidorov, Olga M. Mikheeva, Larissa A. Zvenigorodskaya, Natalia A. Malkina, Daria A. Synkova

“…Late diagnosis of PHPT leads to the development of severe complications (osteoporetic fractures, renal failure) and an increased risk of premature death. …”
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Renal‐hepatic‐pancreatic dysplasia type 2: Perinatal lethal condition or a multisystemic disorder with variable expressivity by Kathryn Gunther, Essam M. Imseis, Joyce P. Samuel, Elizabeth A. Hillman, Tiina H. Ojala, Timo Jahnukainen, Paul R. Hillman

“…Of the four cases living past the first year of life, one case died at 5 years secondary to renal failure, the other at 30 months secondary to liver and kidney failure. …”
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Rapidly Progressing to ESRD in an Individual with Coexisting ADPKD and Masked Klinefelter and Gitelman Syndromes by Ramón Peces, Carlos Peces, Rocío Mena, Emilio Cuesta, Fe Amalia García-Santiago, Marta Ossorio, Sara Afonso, Pablo Lapunzina, Julián Nevado

“…We here report a male patient with ADPKD who developed early chronic renal failure leading to ESRD, presenting with an intracranial aneurysm and infertility. …”
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Angiotensin-converting enzyme inhibitors versus angiotensin receptor blockers for diabetic nephropathy: a retrospective comparison by Nicolás Roberto Robles, Baldomero Romero, Enrique Fernandez-Carbonero, Emilio Sánchez-Casado, Juan Jose Cubero

“…At 36 months, the comparative odds ratio for having started renal replacement therapy or reaching end-stage renal failure was 0.246 (95% confidence interval 0.114—0.531, p<0.001 for chi-square and likelihood ratio tests). …”
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Streptococcal toxic shock syndrome in an adolescent by N. A. Ryzhakova, T. S. Krivonogova, E. V. Golikova, V. A. Zhelev, E. V. Loshkova, A. A. Terentyeva, A. L. Solnyshko, T. V. Vaganova, T. S. Liulka

“…The final diagnosis: Acute post-streptococcal glomerulonephritis with a debut in the form of streptococcal toxic shock syndrome, a period of extensive clinical and laboratory changes, with a decrease in the debut of kidney function in the form of acute renal failure, recovery period. Against the background of the treatment (2 courses of antibiotic therapy  (cefotaxime, amoxicillin), infusion therapy, pulse therapy with metipred  (5  pulses), double transfusion of  freshly frozen plasma, prednisone, lasix, veroshpiron, enap, curantil, heparin, and other accompanying therapy), pronounced positive clinical and laboratory dynamics was noted. …”
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Buyang Huanwu decoction affects gut microbiota and lipid metabolism in a ZDF rat model of co-morbid type 2 diabetes mellitus and obesity: An integrated metabolomics analysis by Mei Liu, Qinmian Zhao, Jiayan Liu, Aijing Huang, XinHua Xia, XinHua Xia

“…Type 2 diabetes mellitus (T2DM) is a chronic disease associated with many severe complications such as blindness, amputation, renal failure, and cardiovascular disease. Currently, the prevention and treatment of T2DM is a major global challenge as the number of aging and obese people is increasing. …”
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Effect of the Protective Role of Long-Term Ischemic Preconditioning on Acute Renal Impairment Due to Re-Ischemic Resection Through TLR-4 and TNF-α Signaling Pathway in Rats by F Gholampour, J Roozbeh, S Janfashan, L Malek Mahal, K Rahimi Jaberi, Z Karimi

“…The RIPerC model consisted of four five-minute cycles (two minutes for closing the left femoral artery and three minutes for re-bleeding) at the onset of ischemic-renal failure. At the end of the resuscitation period, urine, blood, and kidney tissue samples were collected for functional, structural, and molecular analysis. …”
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