Clinical and Laboratory Characteristics of Acute Kidney Injury in Critically Ill Children: A Single Center Study by Faeghe Baryar Langroudi, Hamid Mohammadjafari, Hani Rostami Rad, Mohaddeseh Momeni, Maedeh Guran, Mohammad Reza Navaeifar

“…Analysis of possible variables contributing to acute kidney injury was made using data up to 48 hours before the onset of renal failure. Results: In 255 patients analyzed, the median age was 18 (IQR, 6-60) months. …”
Get full text

Tranexamic acid in pertrochanteric fractures: a retrospective analysis of perioperative outcomes after fixation with a proximal femoral nail by John Hanke, Thomas Mendel, Matthias Wingert, Philipp Schenk, Markus Heinecke, Arne Wilharm

“…A trend could be seen towards a reduction in postoperative renal failure. No complications occurred resulting from the administration of tranexamic acid. …”
Get full text

Symmetric Dimethylarginine is a Promising Biomarker for the Early Detection of Age-Related Kidney Dysfunction in Zoo Felids by Youn Soong-Hee, Efladl Ahmed K., Chung Myung-Jin, Jung Eun, Shin Ki-Yong, Shin Hyeon-Joo, Yang Joon-Young, Heo Kwang-Seok, Chung Dong-Hee, Yim Jae-Hyuk, Son Ji-Yoon, Lee Eun-Joo, Hong Il-Hwa, Jeong Kyu-Shik

“…Chronic renal failure is one of the leading causes of death in African lions, cheetahs, and tigers. …”
Get full text

Complications and Mortality after Surgeries in Patients with Prior Stroke Who Received General and Neuraxial Anesthesia: A Propensity-Score Matched Study by Yi-Ting Kao, Chuen-Chau Chang, Chun-Chieh Yeh, Chaur-Jong Hu, Yih-Giun Cherng, Ta-Liang Chen, Chien-Chang Liao

“…Among the 4903 matched pairs with prior stroke, patients with GA had higher risks of pneumonia (OR 2.00, 95% CI 1.62–2.46), pulmonary embolism (OR 3.30, 95% CI 1.07–10.2), acute renal failure (OR 3.51, 95% CI 1.13–2.10), intensive care unit stay (OR 3.74, 95% CI 3.17–4.41), and in-hospital mortality (OR 2.02, 95% CI 1.16–3.51) than those who received NA. …”
Get full text

Clinical profiles and outcomes of young versus elderly patients with multiple myeloma: A retrospective observational study from a tertiary cancer center in South India by Angadi Veerendra, Nitesh Anand, Sachet Saxena, Manjunath Nandennavar, Shashidhar Vishvesh Karpurmath

“…In terms of clinical presentation in the young versus elderly cohorts, renal failure was less (5 [17.2%] vs. 19 [35.8%], respectively; P, 0.038), while anemia (22 [75.9%] versus 38 [76%], respectively; P, 0.496) and hypercalcemia (7 [24.1%] versus 9 [23%], respectively; P, 0.458) occurred to a similar extent. …”
Get full text

Proteinase 3 (PR3)-Antineutrophil Cytoplasmic Antibody in a Patient with Minimal Change Disease: An Unusual Finding by Joana Freitas, Inês Sala, João Oliveira, Andreia Campos, Sofia Santos, Josefina Santos, António Cabrita

“…This reports to an 86-year-old Caucasian woman without relevant past medical history and a normal renal function one month before presentation with sudden-onset nephrotic syndrome and rapidly progressive renal failure. Renal ultrasound was normal. Autoimmune screening using enzyme-linked immunosorbent assay (ELISA) revealed PR3-ANCA high titers (238.7UQ). …”
Get full text

Rhabdomyolysis caused by interaction between rosuvastatin and vadadustat: a case report by Keiki Sakurama, Yuki Iguchi, Sara Haruki, Yusuke Hata, Madoka Hiraga, Shinya Yumoto, Yutaka Kai

“…Case presentation A 62-year-old male with medical records of hypertension, myocardial infarction, chronic renal failure, renal anemia, dyslipidemia, and alcoholic liver disease. …”
Get full text

Severe Multiorgan Failure Following Yellow Fever Vaccination by Cristina Domingo, Judith Lamerz, Daniel Cadar, Marija Stojkovic, Philip Eisermann, Uta Merle, Andreas Nitsche, Paul Schnitzler

“…Three days later he sought medical attention and was transferred to the University Hospital Heidelberg with beginning multiorgan failure and severe septic shock, including hypotonia, tachypnea, thrombopenia, and acute renal failure the same day. Within one week after vaccination, antibodies against YF virus were already detectable and progressively increased over the next two weeks. …”
Get full text

Probabilistic modelling is superior to deterministic approaches in the human health risk assessment: an example from a tribal stretch in central India by Rajkumar Herojeet, Rakesh K. Dewangan, Pradeep K. Naik, Janak R. Verma

“…Medical teams visiting the area reported severe renal failure and blamed the local eating and drinking habits as causative factors. …”
Get full text

Clinical condition and cardiovascular risk factors displaying neoatherosclerosis in stented coronary arteries with developing restenosis by V. P. Mazaev, A. A. Komkov, S. V. Ryazanova

“…Other risk factors: arterial hypertension, hypercholesterolemia, diabetes mellitus, insulin dependency, chronic renal failure, smoking, alcohol abuse, family cardiovascular anamnesis, body mass index, — did not show statistically significant differences between the groups.Conclusion. …”
Get full text

Effect of the Timing of Admission Upon Patient Prognosis in the Intensive Care Unit: Off-hours and On-hours by Yeliz Bilir, Fulya Ciyiltepe, Dilara Çopur, Kemal Tolga Saraçoğlu

“…There was no significant difference between the two groups in terms of demographic data, except that chronic renal failure (18.2%, p=0.024) was more common as a comorbidity in TO patients. …”
Get full text

Successful Treatment with Osimertinib Based on Therapeutic Drug Monitoring in a Hemodialysis Patient with Non-Small Cell Lung Cancer: A Case Report by Keisuke Tabata, Masaya Aoki, Ryo Miyata, Tadashi Umehara, Aya Harada-Takeda, Go Kamimura, Toshiyuki Nagata, Ryuya Okizono, Hideyuki Terazono, Yasuo Takeda, Takayuki Suetsugu, Kazuhiro Ueda, Masami Sato

“…Hemodialysis was started three times a week because chronic renal failure worsened during treatment. Although the subsequent administration of osimertinib (80 mg daily) resulted in a tumor shrinkage and a gradual increase in the plasma concentration of osimertinib, which resulted in grade 3 general fatigue, reducing the dosage of osimertinib decreased its plasma concentration, leading to an improvement in his adverse event. …”
Get full text

Dual-Energy CT Applications in Urological Diseases by Michaela Cellina, Maria Vittoria Bausano, Daniele Pais, Vittoria Chiarpenello, Marco Costa, Zakaria Vincenzo, Maurizio Cè, Carlo Martinenghi, Giancarlo Oliva, Gianpaolo Carrafiello

“…This can be critical for early detection and management of these disorders, which can reduce the risk of renal failure and improve outcomes. DECT is a valuable tool in the urological field that can provide clinicians with detailed and accurate information for the diagnosis and treatment planning of various urological conditions. …”
Get full text

Isolation, Identification and Antifungal Susceptibility Testing of Candida Species: A Cross-sectional Study from Manipur, India by Urvashi Chongtham, Debina Chanu Athokpam, Rajkumar Manojkumar Singh

“…Introduction: Candidiasis is an opportunistic infection which occurs due to indiscriminate and prolonged use of broad-spectrum antimicrobials, corticosteroids, immunosuppressive agents, diabetes mellitus, Human Immunodeficiency Virus (HIV), chronic renal failure, haemodialysis, renal transplantation or indwelling urinary catheter. …”
Get full text

Hemoglobin A1c in Patients with Diabetes Predict Long-Term Mortality Following Coronary Artery Surgery by Muhammad Abu Tailakh, Shlomo-yaron Ishay, Jenan Awesat, Liat Poupko, Gidon Sahar, Victor Novack

“…Multivariable Cox proportional hazards regression, adjusted for age, gender, smoking status, chronic obstructive pulmonary disease, hypertension, chronic renal failure, old myocardial infarction, number of coronary artery bypass surgeries, and post-operative glycemic control, showed a hazard ratio of 2.67 for long-term ACM (<i>p</i> = 0.001) in patients with HbA1c > 7%. …”
Get full text

Intraoperative Extracorporeal Support during Lung Transplantation: Not Just for the High-Risk Patient by Daniel Laskey, Brian Housman, Gbalekan Dawodu, Scott Scheinin

“…Studies show that the routine use of ECMO during transplantation decreases the rate of primary graft dysfunction and many adverse outcomes including ventilator time, need for tracheostomy, renal failure, post-operative ECMO requirements, and others. …”
Get full text

Peri-Procedural Management of Direct-Acting Oral Anticoagulants (DOACs) in Transcatheter Miniaturized Leadless Pacemaker Implantation by François Diederik Regoli, Ardan M. Saguner, Angelo Auricchio, Andrea Demarchi, Elena Pasotti, Giulio Conte, Maria Luce Caputo, Tardu Özkartal, Alexander Breitenstein

“…Patients treated with DOAC less often had structural heart disease, diabetes mellitus, and advanced renal failure. The rate of major peri-procedural complications did not differ between groups 1A (<i>n</i> = 115) and 1B (<i>n</i> = 77) (2.6% and 3.8%, <i>p</i> = 0.685). …”
Get full text

The Effect of Calcium Channel Blocker Verapamil on Gentamicin Nephrotoxicity in Rats by Nenad Stojiljković, Slavimir Veljković, Dragan Mihailović, Milan Stoiljković, Dragan Radovanović, Pavle Ranđelović

“… Aminoglycoside antibiotics are obligated nephrotoxins and inevitably cause renal failure during prolonged use. Experimental models of gentamicin-induced nephrotoxicity have shown histopathological, ultrastructural and functional alteration with blood urea nitrogen and serum creatinine increase leading to acute renal insufficiency (ARI). …”
Get full text

Abnormal Lipoproteins Trigger Oxidative Stress-Mediated Apoptosis of Renal Cells in LCAT Deficiency by Monica Gomaraschi, Marta Turri, Arianna Strazzella, Marie Lhomme, Chiara Pavanello, Wilfried Le Goff, Anatol Kontush, Laura Calabresi, Alice Ossoli

“…LCAT deficiency is characterized by an abnormal lipoprotein profile with severe reduction in plasma levels of high-density lipoprotein (HDL) cholesterol and the accumulation of lipoprotein X (LpX). Renal failure is the major cause of morbidity and mortality in FLD patients; the pathogenesis of renal disease is only partly understood, but abnormalities in the lipoprotein profile could play a role in disease onset and progression. …”
Get full text

Patients with CKD Secondary to Glomerular Disorders have Lower Arterial Stiffness, as Compared to Hypertensive and Diabetic CKD by Ori Lencovsky, Avital Angel-Korman, Erick Glasswine, Rotem Tal-Ben Ishay, Mor Amital, Olga Kukuy, Adi Leiba

“…Diabetes, hypertension, and glomerular disorders are the leading causes of CKD and renal failure. The question which etiology contributes more to this vascular phenomenon-hypertensive and diabetic CKD or CKD secondary to immune-mediated glomerulonephritis—remained unclear. …”
Get full text