Perioperative Complications of Open Spine Surgery in Older Adults over 90 Years of Age by Takeru Tsujimoto, Masahiro Kanayama, Kota Suda, Fumihiro Oha, Miki Komatsu, Yukitoshi Shimamura, Masaru Tanaka, Daisuke Ukeba, Yuichi Hasegawa, Tomoyuki Hashimoto, Masahiko Takahata, Norimasa Iwasaki

“…Major complications (deep surgical site infection, cardiac event, respiratory disorder, gastrointestinal hemorrhage, and renal failure) occurred in 13 cases, and the rate of overall perioperative complications was 45.8%. …”
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International Multicentre Study of <i>Candida auris</i> Infections by Nirav Pandya, Yasemin Cag, Nenad Pandak, Abdullah Umut Pekok, Aruna Poojary, Folusakin Ayoade, Teresa Fasciana, Anna Giammanco, Hulya Caskurlu, Dhanji P. Rajani, Yogesh Kumar Gupta, Ilker Inanc Balkan, Ejaz Ahmed Khan, Hakan Erdem

“…<b>Results:</b> Significant risk factors for <i>C. auris</i> infection include the age group of 61–70 years (39%), recent history of ICU admission (63%), diabetes (63%), renal failure (52%), presence of CVC (91%) and previous history of antibiotic treatment (96%). …”
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Central aortic versus axillary artery cannulation for aortic arch surgeryCentral MessagePerspective by Megan M. Chung, BA, Kerry Filtz, MD, Michael Simpson, MD, Samantha Nemeth, MS, MA, MPH, Yaagnik Kosuri, MD, Paul Kurlansky, MD, Virendra Patel, MD, MPH, Hiroo Takayama, MD, PhD

“…The primary outcome was failure to achieve uneventful recovery, defined as having experienced at least 1 of the following: in-hospital mortality, stroke, transient ischemic attack, bleeding requiring reoperation, prolonged ventilation, renal failure, mediastinitis, surgical site infection, and pacemaker or implantable cardiac defibrillator implantation. …”
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PATHOLOGICAL ANATOMY OF INFECTION CAUSED BY SARS-COV-2 by E. A. Kogan, Yu. S. Berezovsky, D. D. Protsenko, T. R. Bagdasaryan, E. M. Gretsov, S. A. Demura, G. A. Demyashkin, D. V. Kalinin, A. D. Kukleva, E. V. Kurilina, T. P. Nekrasova, N. B. Paramonova, A. B. Ponomarev, S. G. Radenska-Lopovok, L. A. Semyonova, A. S. Tertychny

“…The thanatogenesis of the disease and the main causes of death are discussed, including acute cardiopulmonary failure, acute renal failure, pulmonary thromboembolism, shock involving multiple organ failure and sepsis. …”
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Clinical outcomes in 2481 unselected real-world patients treated with a polymer-free sirolimus-eluting stent: 3 years results from the NANO multicenter Registry by Yi Dai, Rutao Wang, Fengying Chen, Yaojun Zhang, Yi Liu, He Huang, Ping Yang, Ruining Zhang, Bo Zheng, Chao Gao, Yundai Chen, Ling Tao

“…The risk factors of diabetes mellitus, acute myocardial infarction, age, chronic renal failure, in-stent restenosis, chronic total occlusion, and left ventricular ejection fraction < 40% were the independent predictors of 3-year TLF. …”
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Evaluation of Hospital-Acquired Stenotrophomonas maltophilia Infections by Meltem AVCI, Onur ÖZGENÇ, Seher Ayten COŞKUNER, Berna BOZCA, Gülşen MERMUT, Ebru ÖKTEM, Neslihan GENÇ, Sabiha ATMACA, Gülşen GÜLOĞLU

“…The most common underlying diseases were malignancies (37%), chronic renal failure (15%), and cardiac failure (15%). Eighty-eight percent of the patients were on antibiotic treatment before infection. …”
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Stratification of diabetes in the context of comorbidities, using representation learning and topological data analysis by Malgorzata Wamil, Abdelaali Hassaine, Shishir Rao, Yikuan Li, Mohammad Mamouei, Dexter Canoy, Milad Nazarzadeh, Zeinab Bidel, Emma Copland, Kazem Rahimi, Gholamreza Salimi-Khorshidi

“…The following endpoints were considered when profiling risk trajectories: major adverse cardiovascular events (MACE), coronary artery disease (CAD), stroke (CVA), heart failure (HF), renal failure (RF), diabetic neuropathy, peripheral arterial disease, reduced visual acuity and all-cause mortality. …”
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Circulating Serum MiRNA-8074 as a Novel Prognostic Biomarker for Multiple Myeloma by Aneta Szudy-Szczyrek, Radosław Mlak, Michał Mielnik, Marcin Mazurek, Sylwia Chocholska, Martyna Podgajna, Michał Szczyrek, Iwona Homa-Mlak, Teresa Małecka-Massalska, Marek Hus

“…In addition to the known prognostic factors, such as ECOG > 1, Durie–Salmon stage III, diagnosis of light chain disease or non-secreting MM, renal failure, hypoalbuminemia, hypercalcemia, high β2-microglobulin, elevated LDH, and t(14;16), a high expression of miRNA-8074 was significantly associated with a higher risk of death (HR = 4.12, 95% CI: 2.20–7.70; <i>p</i> = 0.0009). …”
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Predictors for Prolonged Intensive Care Unit Stay After Adult Orthotopic Liver Transplantation by Aycan Kundakcı, Arash Pirat, Özgür Kömürcü, Adnan Torgay, Hamdi Karakayalı, Gülnaz Arslan, Mehmet Haberal

“…Multivariate logistic regression revealed that only higher MELD scores (odds ratio: 1.4, CI%95:1.2-1.7, p=0.010) was an independent risk factor for prolonged ICU stay after liver transplantation Patients who had developed renal failure in the early postoperative period according to the RIFLE criteria had stayed in the ICU longer [74% (23) vs 44%(36), p=0.006]. …”
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Brown Spider (<i>Loxosceles</i>) Venom Toxins as Potential Biotools for the Development of Novel Therapeutics by Daniele Chaves-Moreira, Fernando Hitomi Matsubara, Zelinda Schemczssen-Graeff, Elidiana De Bona, Vanessa Ribeiro Heidemann, Clara Guerra-Duarte, Luiza Helena Gremski, Carlos Chávez-Olórtegui, Andrea Senff-Ribeiro, Olga Meiri Chaim, Raghuvir Krishnaswamy Arni, Silvio Sanches Veiga

“…Brown spider envenomation results in dermonecrosis with gravitational spreading characterized by a marked inflammatory reaction and with lower prevalence of systemic manifestations such as renal failure and hematological disturbances. Several toxins make up the venom of these species, and they are mainly peptides and proteins ranging from 5&#8722;40 kDa. …”
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Racial and Ethnic Disparities in Management and Outcomes of Cardiac Arrest Complicating Acute Myocardial Infarction by Anna V. Subramaniam, Sri Harsha Patlolla, Wisit Cheungpasitporn, Pranathi R. Sundaragiri, P. Elliott Miller, Gregory W. Barsness, Malcolm R. Bell, David R. Holmes, Saraschandra Vallabhajosyula

“…Black patients admitted with AMI‐CA were more likely to be female, with more comorbidities, higher rates of non–ST‐segment–elevation myocardial infarction, and higher neurological and renal failure. Admissions of patients of Black and other races/ethnicities underwent coronary angiography (61.9% versus 70.2% versus 73.1%) and percutaneous coronary intervention (44.6% versus 53.0% versus 58.1%) less frequently compared to patients of white race (p<0.001). …”
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Comparison of Balanced Crystalloids versus Normal Saline in Critically Ill Patients: A Systematic Review with Meta-Analysis and Trial Sequential Analysis of Randomized Controlled T... by Chen Y, Gao Y

“…Balanced crystalloids were associated with lower mortality compared with normal saline (risk ratio [RR]=0.96; 95% confidential interval [CI] 0.93, 1; p=0.03; I2=0) and lower incidence of acute kidney injury/acute renal failure (RR =0.93; 95% CI = 0.87, 0.99; p=0.03). …”
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One Health Approach to Leptospirosis: Dogs as Environmental Sentinels for Identification and Monitoring of Human Risk Areas in Southern Brazil by Natacha Sohn-Hausner, Louise Bach Kmetiuk, Evelyn Cristine da Silva, Helio Langoni, Alexander Welker Biondo

“…Associated risk factors for leptospirosis in dogs and humans according to multiple regression included healthy dogs (<i>p</i> = 0.02, odds ratio—OR = 0.17, confidence interval of 95%CI 0.03–0.71) with indoor access (<i>p</i> = 0.059, OR = 5.12, 95%CI 1.10–37.7) and human males (<i>p</i> = 0.042, OR = 2.44, 95%CI 1.08–6.11) with presenting calf pain (<i>p</i> = 0.005, OR = 3.14, 95%CI 1.46–7. 14), jaundice (<i>p</i> < 0.001, OR = 4.61, 95%CI 2.11–10.10) and renal failure (<i>p</i> = 0.008, OR = 4.49, 95%CI 1.49–13.76). …”
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OXIDATIVE STRESS AND EARLY POST-OPERATIVE COMPLICATIONS IN CARDIAC SURGERY by Zh. S. Filippovskaya, O. N. Gerasimenko, O. A. Grebenchikov, R. A. Zinovkin, R. N. Larkov, O. N. Ulitkina, Yu. V. Skripkin, V. V. Likhvantsev

“…Goal of the article: to investigate the impact of oxidative stress assessed as per the level of carbonyl proteins in blood plasma on systemic inflammation response syndrome (SIRS), acute heart (AHF) and renal failure (ARF) in cardiac surgery. Methods. Prospective observational cohort study was conducted in order to investigate the relation of oxidative stress intensity, assessed as per the level of carbonyl peptides in blood plasma, and development of SIRS, AHF, ARF in the patients undergoing cardiac surgery. 67 adults patients admitted to Cardiac Intensive Care Department of M.F. …”
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Metabolic Syndrome and Heart Transplantation: An Underestimated Risk Factor? by Sandro Sponga, Sandro Sponga, Igor Vendramin, Veronica Ferrara, Michela Marinoni, Giulia Valdi, Concetta Di Nora, Chiara Nalli, Giovanni Benedetti, Daniela Piani, Andrea Lechiancole, Maria Parpinel, Uberto Bortolotti, Ugolino Livi, Ugolino Livi

“…At the univariate analysis, risk factors for mortality were pre-HTx MetS (HR 1.86, p &lt; 0.01), hypertension (HR 2.46, p &lt; 0.01), hypertriglyceridemia (HR 1.50, p=0.03), chronic renal failure (HR 2.95, p &lt; 0.01), MetS and diabetes at 1 year follow-up (HR 2.00, p &lt; 0.01; HR 2.02, p &lt; 0.01, respectively). …”
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Prognostic Value of Fractional Excretion of Urea Nitrogen at Discharge in Acute Decompensated Heart Failure by Kazutaka Nogi, Rika Kawakami, Tomoya Ueda, Maki Nogi, Satomi Ishihara, Yasuki Nakada, Yukihiro Hashimoto, Hitoshi Nakagawa, Taku Nishida, Ayako Seno, Kenji Onoue, Tsunenari Soeda, Makoto Watanabe, Yoshihiko Saito

“…Patients were divided into two groups according to a FEUN cut‐off value of 35%, commonly used in pre‐renal failure. The FEUN <35% (low‐FEUN) group included 224 patients (48.1%), and the all‐cause mortality rate for the total cohort was 37.1%. …”
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Multidrug-resistant gram-negative bacteria in patients with COVID-19: An epidemiological and clinical study by Gleyce Hellen de Almeida de Souza, Alexandre Ribeiro de Oliveira, Marcelo dos Santos Barbosa, Luana Rossato, Kerly da Silva Barbosa, Simone Simionatto

“…Several factors associated with mortality were identified among patients with COVID-19 infected with MDR-GNB, including the use of a urinary catheter; renal failure; and the origin of bacterial cultures such as tracheal secretion, exposure to carbapenem antibiotics, and polymyxin. …”
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Development and validation of a prediction model for mechanical ventilation based on comorbidities in hospitalized patients with COVID-19 by Yi Zhang, Yi Zhang, Yang-Jie Zhu, Dao-Jun Zhu, Dao-Jun Zhu, Bo-Yang Yu, Tong-Tong Liu, Lu-Yao Wang, Lu-Lu Zhang

“…The prediction model incorporating age, sex, and 11 other comorbidities (deficiency anemias, congestive heart failure, coagulopathy, dementia, diabetes with chronic complications, complicated hypertension, neurological disorders unaffecting movement, obesity, pulmonary circulation disease, severe renal failure, and weight loss) demonstrated moderate discrimination (area under the curve, 0.715; 95% confidence interval, 0.709–0.722), good calibration (Brier score = 0.070, slope = 1, intercept = 0) and a clinical net benefit with a threshold probability ranged from 2 to 34% in the training set. …”
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Estimation of the Difference in Colistin Plasma Levels in Critically Ill Patients with Favorable or Unfavorable Clinical Outcomes by Jose Sanabria, Vivian Garzón, Tatiana Pacheco, Maria-Paula Avila, Julio-Cesar Garcia, Diego Jaimes, Angela Torres, Rosa-Helena Bustos, Javier Escobar-Perez, Deisy Abril

“…There was higher mortality in patients with subtherapeutic levels (18% vs. 0%), and additionally, there was a greater rate of renal failure in the group with higher therapeutic levels (50% vs. 20.7%). …”
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Immunosuppressive strategies in face and hand transplantation: a comprehensive systematic review of current therapy regimens and outcomes by Lioba Huelsboemer, Sam Boroumand, Alejandro Kochen, Alejandro Kochen, Alna Dony, Alna Dony, Jake Moscarelli, Sacha C. Hauc, Viola A. Stögner, Richard N. Formica, Bohdan Pomahac, Martin Kauke-Navarro

“…This systematic review summarizes the current body of literature on immunosuppressive regimens used in face and hand transplants while summarizing their outcome in terms of rejection, renal failure, and infections.MethodsA systematic search of electronic databases was conducted to identify relevant studies from 1998 until July 1st, 2023. …”
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