Renal Impairment Detectors: IGFBP-7 and NGAL as Tubular Injury Markers in Multiple Myeloma Patients by Karolina Woziwodzka, Jolanta Małyszko, Ewa Koc-Żórawska, Marcin Żórawski, Paulina Dumnicka, Artur Jurczyszyn, Krzysztof Batko, Paulina Mazur, Małgorzata Banaszkiewicz, Marcin Krzanowski, Paulina Gołasa, Jacek A. Małyszko, Ryszard Drożdż, Katarzyna Krzanowska

“…This study aimed to investigate the correlation between new biomarkers and acclaimed parameters of renal failure, MM stage, and prognosis. <i>Materials and Methods</i>: The examined parameters included: urinary and serum cystatin-C, IGFBP-7, and TIMP-2, and urinary NGAL monomer in 124 enrolled patients. …”
Get full text

Incidence, predictors and outcomes of hematoma after ICD implantation: An analysis of a nationwide database of 85,276 patients by Arun Raghav Mahankali Sridhar, Vivek Yarlagadda, Arun Kanmanthareddy, Sravanthi Parasa, Ryan Maybrook, Buddhadeb Dawn, Yeruva Madhu Reddy, Dhanunjaya Lakkireddy

“…Increased age (p < 0.001), and comorbidities such as congestive heart failure (odds ratio (OR) – 1.86, p < 0.001), coagulopathy (OR - 2.3, p < 0.001) and renal failure (OR - 1.52, p < 0.001) were associated with an increased risk of pocket hematoma formation. …”
Get full text

Clinical relevance of transcranial Doppler in a cardiac surgery setting: embolic load predicts difficult separation from cardiopulmonary bypass by Stéphanie Jarry, Etienne J. Couture, William Beaubien-Souligny, Armindo Fernandes, Annik Fortier, Walid Ben-Ali, Georges Desjardins, Karel Huard, Tanya Mailhot, André Y. Denault

“…The importance of cerebral microemboli during cardiac surgery has been linked to the increased incidence of postoperative renal failure, right ventricular dysfunction, and hemodynamic instability. …”
Get full text

Increasing Incremental Burden of Surgical Bleeding Associated with Multiple Comorbidities as Measured by the Elixhauser Comorbidity Index: A Retrospective Database Analysis by Afolabi M, Johnston SS, Tewari P, Danker WA

“…Outcomes, all measured as in-hospital during index, included bleeding (diagnosis and/or intervention for bleeding), transfusion-associated complications (diagnosis of infection, acute renal failure, or vascular events), and incremental total hospital costs associated with bleeding. …”
Get full text

Implementing an Ensemble Learning Model with Feature Selection to Predict Mortality among Patients Who Underwent Three-Vessel Percutaneous Coronary Intervention by Yen-Chun Huang, Kuan-Yu Chen, Shao-Jung Li, Chih-Kuang Liu, Yang-Chao Lin, Mingchih Chen

“…Age, congestive heart failure (CHF), and chronic renal failure (CRF) are mortality’s most important variables. …”
Get full text

The implication of miR-200a and miR-132 expression and their correlations with NF-κB/TNF-alpha signaling in adults with diabetic nephropathy by Zienab Negeem, Adel Abdel Moneim, Basant Mahmoud, Amr E. Ahmed, Abeer M. Abd El-Hameed, Areej A. Eskandrani, Nabil A. Hasona

“…Aim: The primary factor causing chronic renal failure is diabetic nephropathy (DN) worldwide. …”
Get full text

Morbidity and Mortality in Non-Obese Compared to Different Classes of Obesity in Patients Undergoing Transtibial Amputations by Senthil Sambandam, Syed Muhammad Mashhood Ali Bokhari, Shirling Tsai, Vishaal Sakthivel Nathan, Tejas Senthil, Heather Lanier, Sergio Huerta

“…Blood loss anemia was more common in Ob-III compared to Ob-I/II patients (OR = 1.2; 95% CI = 1.1–1.4); blood transfusions were less commonly required in Ob-I/II (OR = 0.8; 95% CI = 0.7–0.9) comparatively; Ob-I/II encountered pneumonia less frequently (OR = 0.9; 95% CI = 0.4–0.9), whereas myocardial infarction was more frequent (OR = 7.0; 95% CI = 2.1–23.6) compared to N-Ob patients. Acute renal failure is more frequent in Ob-I/II (OR = 1.2; 95% CI = 1.0–1.3) and Ob-III (OR = 1.8; 95% CI = 1.6–1.9) compared to the N-Ob cohort. …”
Get full text

Efficacy of Afatinib in the Treatment of Patients with Non-Small Cell Lung Cancer and Head and Neck Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis by Nian N. N. Maarof, Abdulsamad Alsalahi, Emilia Abdulmalek, Sharida Fakurazi, Bimo Ario Tejo, Mohd Basyaruddin Abdul Rahman

“…From a clinical viewpoint of severity, interstitial lung disease, dyspnea, pneumonia, acute renal failure, and renal injury were rarely incident adverse events in the afatinib group. …”
Get full text

Successful Treatment of Acute Uric Acid Nephropathy with Rasburicase in a Primary Central Nervous System Lymphoma Patient Showing a Dramatic Response to Methotrexate—Case Report by Yoshihiro Mouri, Manabu Natsumeda, Noritaka Okubo, Taro Sato, Taiki Saito, Kohei Shibuya, Shiori Yamada, Jotaro On, Yoshihiro Tsukamoto, Masayasu Okada, Makoto Oishi, Takeyoshi Eda, Junko Murai, Hiroshi Shimizu, Akiyoshi Kakita, Yukihiko Fujii

“…After the initiation of chemotherapy, the patient experienced a gout attack, and blood examination revealed acute renal failure (ARF) and hyperuricemia. The considered causes of ARF included MTX toxicity and acute uric acid nephropathy. …”
Get full text

Role of arginine and/or taurine in protection against gentamicin-induced nephrotoxicity in male and female rats by Wafaa M Ismaeil, Amal H Emara

“…L-arginine (2-amino-5-guanidino-pentanoic acid) has a protective role on renal failure that induced by gentamicin administration and it may decrease the tubular reabsorption of another cationic substance, gentamicin due to its cationic structure. …”
Get full text

The role of allogeneic platelet-rich plasma in patients with diabetic foot ulcer: Current perspectives and future challenges by Min He, Min He, Tianyi Chen, Yuhuan Lv, Peiyang Song, Bo Deng, Xuewen Guo, Shunli Rui, Johnson Boey, David G. Armstrong, Yu Ma, Wuquan Deng

“…Patients with age-related diseases, such as diabetes, tumors, renal failure and stroke are prone to soft tissue and skin injury, compounded by slowed healing in aging. …”
Get full text

Relationship between the microenvironment and survival in kidney transplantation: a bibliometric analysis from 2013 to 2023 by Chun-Lian Huang, Xin-Yu Fu, Yi Feng, Xiao-Kang Li, Xiao-Kang Li, Yi Sun, Xin-Li Mao, Xin-Li Mao, Xin-Li Mao, Shao-Wei Li, Shao-Wei Li, Shao-Wei Li

“…BackgroundKidney transplantation is considered the most effective treatment for end-stage renal failure. Recent studies have shown that the significance of the immune microenvironment after kidney transplantation in determining prognosis of patients. …”
Get full text

An investigation of geographical clusters of leptospirosis during the outbreak in Pangandaran, West Java, Indonesia by Mutiara Widawati, Pandji Wibawa Dhewantara, Raras Anasi, Tri Wahono, Rina Marina, Intan Pandu Pertiwi, Agus Ari Wibowo, Andri Ruliansyah, Muhammad Umar Riandi, Dyah Widiastuti, Endang Puji Astuti

“…Severe outcomes including renal failure, lung failure, and hepatic necrosis were reported in up to 5% of the cases. …”
Get full text

Oral Acid Load Down-Regulates Fibroblast Growth Factor 23 by Angela Vidal, Carmen Pineda, Ana I. Raya, Rafael Rios, Azahara Espartero, Juan R. Muñoz-Castañeda, Mariano Rodriguez, Escolastico Aguilera-Tejero, Ignacio Lopez

“…Fibroblast growth factor 23 (FGF23) is a bone-derived hormone that is elevated during renal failure. The relationship between metabolic acidosis and FGF23 remains unclear. …”
Get full text

Mediterranean Diet Score: Associations with Metabolic Products of the Intestinal Microbiome, Carotid Plaque Burden, and Renal Function by Michael Pignanelli, Caroline Just, Chrysi Bogiatzi, Vincent Dinculescu, Gregory B. Gloor, Emma Allen-Vercoe, Gregor Reid, Bradley L. Urquhart, Kelsey N. Ruetz, Thomas J. Velenosi, J. David Spence

“…Metabolic products of the intestinal microbiome such as trimethylamine N-oxide (TMAO) that accumulate in renal failure (gut-derived uremic toxins, GDUTs) affect atherosclerosis and increase cardiovascular risk. …”
Get full text

Glycylglycine promotes the solubility and antigenic utility of recombinant HCV structural proteins in a point-of-care immunoassay for detection of active viremia by Heba Shawky, Ashraf A. Tabll, Reem M. Elshenawy, Naiera M. Helmy, Rehab I. Moustafa, Yasser K. Elesnawy, Marwa M. Abdelghany, Yasmine S. El-Abd

“…The antigenic performance of soluble proteins was assessed against 63 HCV-seronegative (Ab−) sera that included normal and interferent sera (HBV and/or chronic renal failure), and 383 HCV-seropositive (Ab+) samples that included viremic (chronic/relapsers) and recovered patients’ sera. …”
Get full text

Vascular endothelial growth factor levels in tuberculosis: A systematic review and meta-analysis. by Amene Saghazadeh, Nima Rezaei

“…There were 1787 patients with TB and 3352 control subjects of eight categories: 107 patients with transudative pleural effusion, 228 patients with congestive heart failure (CHF)/chronic renal failure (CRF), 261 patients with empyema and parapneumonic effusion (PPE), 241 patients with cirrhosis, 694 healthy controls (with latent TB infection or uninfected individuals), 20 patients with inactive tuberculous meningitis (TBM), 123 patients with non-TBM, and 1678 patients with malignancy. …”
Get full text

Off‐Hour Admission and Mortality Risk for 28 Specific Diseases: A Systematic Review and Meta‐Analysis of 251 Cohorts by Yanfeng Zhou, Wenzhen Li, Chulani Herath, Jiahong Xia, Bo Hu, Fujian Song, Shiyi Cao, Zuxun Lu

“…Weaker (odds ratio <1.19) but statistically significant association was noted for renal failure, traumatic brain injury, heart failure, intracerebral hemorrhage, subarachnoid hemorrhage, stroke, gastrointestinal bleeding, myocardial infarction, chronic obstructive pulmonary disease, and bloodstream infections. …”
Get full text

Epidemiology of Cytomegalovirus among Patients Undergoing Hemodialysis in Sari, Iran 2017-2018 by Sedigheh Aghajanian, Amirhosein Rangani, Reza Alizadeh-Navaei, Fatemeh Espahbodi, Hamed Jafarpour, Keyvan Heydari, Alireza Salehi, Mohammad Zahedi, Amirhossein Hessami, Alireza Azad, Soheil Azizi

“…Background and purpose: Cytomegalovirus (CMV) is one of the most important pathogens in immunocompromised patients, those who need regular blood transfusion, and renal failure patients undergoing hemodialysis. The aim of this investigation was to study the epidemiology of cytomegalovirus in hemodialysis patients in Sari, Iran. …”
Get full text

Stroke volume variation compared with pulse pressure variation and cardiac index changes for prediction of fluid responsiveness in mechanically ventilated patients by Randa Aly Soliman, Shereif Samir, Ayman el Naggar, Khalaf El Dehely

“…Excluded are patients with cardiogenic shock, acute pulmonary edema, LVEF <50%, atrial fibrillation, frequent ectopics, significant aortic or mitral valve abnormalities or renal failure. Candidates were subjected to thorough clinical evaluation, lab investigation and ECG. …”
Get full text