Elderly Suffering from ST-Segment Elevation Myocardial Infarction—Results from a Database Analysis from Two Mediterranean Medical Centers by Leor Perl, Alfonso Franzé, Fabrizio D’Ascenzo, Noa Golomb, Amos Levi, Hana Vaknin-Assa, Gabriel Greenberg, Abid Assali, Gaetano M. De Ferrari, Ran Kornowski

“…<b>Results</b>: More octogenarian patients were female (40.8 vs. 31.9 septuagenarians and 26.5% under 70 y, <i>p</i> < 0.01), had hypertension (79.5 vs. 69.5 and 45.9%, <i>p</i> < 0.01), renal failure (32.5 vs. 20.1 and 5.2%, <i>p</i> < 0.01), and a lower left-ventricular ejection fraction (42.0 vs. 44.9 and 47.6%, <i>p</i> = 0.012). …”
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RELATIONSHIP OF MULTIFOCAL ATHEROSCLEROSIS AND RENAL DYSFUNCTION WITH IN-HOSPITAL COMPLICATIONS AFTER CORONARY BYPASS OPERATION IN ISCHEMIC HEART DISEASE by K. S. Shafranskaya, M. V. Zykov, V. V. Kashtalap, O. K. Kuzmina, I. S. Bykova, V. N. Karetnikova, A. N. Sumin, S. V. Ivanov S, O. L. Barbarash

“…The prevalence of worse outcomes was assessed after the operation (myocardial infarction, stroke, acute renal failure, remediastinotomy, death) during in-hospital period.Results. …”
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A case of kidney transplantation for complete C4 deficiency with recurrent IgM-monoclonal gammopathy of renal significance (MGRS) associated nephropathy by Yu Kijima, Tomokazu Shimizu, Shinya Kato, Kana Kano, Toshihide Horiuchi, Taiji Nozaki, Kazuya Omoto, Masashi Inui, Hiroshi Toma, Shoichi Iida, Toshio Takagi

“…A 45-year-old male patient presented with end-stage renal failure due to membranoproliferative glomerulonephritis (MPGN). …”
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Silent Lupus Nephritis: Renal Histopathological Profile and Early Detection with Urinary Monocyte Chemotactic Protein 1 by Gouda W, Abd elaziz Alsaid A, Abbas AS, Abdel-Aziz TM, Shoaeir MZ, Abd Elazem AAS, Sayed MH

“…Overt LN (OLN) symptoms might vary from asymptomatic microscopic hematuria to renal failure. However, when there are no clinical or laboratory indicators of renal involvement, some people with silent LN (SLN) may have pathological evidence of renal involvement identified by renal biopsy. …”
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Postoperative outcomes, predictors and trends of mortality and morbidity in patients undergoing hip fracture surgery with underlying aortic stenosis: a nationwide inpatient sample... by Shahzad Hassan, Waqas Anwar, Shivani Mehta, Muhammad Iftikhar Hanif, Abdallah Kamouh, Alexander J. Blood

“…AS was linked to higher adjusted odds of postoperative mortality (OR, 1.2 [CI, 1.1–1.5]) and complications such as acute myocardial infarction (OR, 1.2 [CI, 1.01–1.4]), cardiogenic shock (OR, 2.0[CI, 1.4–2.9]) and acute renal failure (OR, 1.1[CI, 1.02–1.2]). While hospital stay duration was comparable in both groups (average 5 days), the AS group incurred higher costs (mean $50,673 vs $44,607). …”
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Cardiac troponin I – A prognostic marker in acute exacerbation of chronic obstructive pulmonary disease by P Amal Johnson, R Narasimhan

“…Exclusion Criteria: Patients with the below mentioned are all excluded from the study - Acute coronary syndrome, post CPR. post cardiac surgery, persistent hemodynamic instability, acute aortic dissection, pulmonary embolism, primary lung diseases other than COPD, patient already on NIV, marked renal failure, severe anaemia, sepsis ,stroke. Study Methodology: The study design is prospective, observational and non-interventional. …”
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Plant Flavonoids on Oxidative Stress-Mediated Kidney Inflammation by Seba Alsawaf, Fatema Alnuaimi, Saba Afzal, Rinku Mariam Thomas, Ayshwarya Lakshmi Chelakkot, Wafaa S. Ramadan, Rawad Hodeify, Rachel Matar, Maxime Merheb, Shoib Sarwar Siddiqui, Cijo George Vazhappilly

“…The kidney is susceptible to reactive oxygen species-mediated cellular injury resulting in glomerulosclerosis, tubulointerstitial fibrosis, tubular cell apoptosis, and senescence, leading to renal failure, and is a significant cause of death worldwide. …”
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A retrospective study of clinico-epidemiological profile of snakebite related deaths at a Tertiary care hospital in Midnapore, West Bengal, India by Rituparna Ghosh, Koushik Mana, Kripasindhu Gantait, Sumana Sarkhel

“…The symptoms of envenomation included local signs of inflammation(100% cases), blisters and necrosis (45% cases), renal failure (20% cases), coagulopathies(57% cases), ptosis(10% cases), dysphagia(2%) and respiratory distress(15% cases). …”
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VHL-recruiting PROTAC attenuates renal fibrosis and preserves renal function via simultaneous degradation of Smad3 and stabilization of HIF-2α by Jiayi Yang, Yuyi Ruan, Dan Wang, Jinjin Fan, Ning Luo, Huiting Chen, Xiaoyan Li, Wei Chen, Xin Wang

“…Abstract Background Renal fibrosis is the pathological foundation of various chronic kidney diseases progressing to end stage renal failure. However, there are currently no nephroprotective drugs targeted to the fibrotic process in clinical practice. …”
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Independent Impact of Peripheral Artery Disease on Percutaneous Coronary Intervention by Leor Perl, Tamir Bental, Hana Vaknin‐Assa, Abid Assali, Pablo Codner, Yeela Talmor‐Barkan, Gabriel Greenberg, Abed Samara, Guy Witberg, Katia Orvin, Ran Kornowski

“…Patients with documented PAD (n=1610, 6.3% of total) were older (66.7±10.8 versus 65.4±12.1, P<0.01), had higher rates of diabetes mellitus (69.3% versus 46.3%, P<0.01), hypertension (92.1% versus 76.1%, P<0.01) and renal failure (38.3% versus 18.2%, P<0.01). There were no differences in the rates of stable versus acute presentations, but less were treated with Prasugrel and Ticagrelor (3.3% versus 8.0% and 7.9% versus 11.9%, respectively, P<0.001 for both). …”
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Pathogenic Variants of <i>SLC22A12</i> (URAT1) and <i>SLC2A9</i> (GLUT9) in Spanish Patients with Renal Hypouricemia: Founder Effect of <i>SLC2A9</i> Variant c.374C>T; p.(T125M) by Ana Perdomo-Ramirez, Elizabeth Cordoba-Lanus, Carmen Jane Trujillo-Frias, Carolina Gonzalez-Navasa, Elena Ramos-Trujillo, Maria Isabel Luis-Yanes, Victor Garcia-Nieto, Felix Claverie-Martin

“…Some patients may present severe complications such as exercise-induced acute renal failure and nephrolithiasis. RHUC is caused by inactivating mutations in the <i>SLC22A12</i> (RHUC type 1) or <i>SLC2A9</i> (RHUC type 2) genes, which encode urate transporters URAT1 and GLUT9, respectively. …”
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Autologous blood transfusion in acute type A aortic dissection decreased blood product consumption and improved postoperative outcomesCentral MessagePerspective by Elizabeth L. Norton, MD, Karen M. Kim, MD, Shinichi Fukuhara, MD, Katelyn P. Monaghan, BS, Aroma Naeem, BA, Xiaoting Wu, PhD, Gorav Ailawadi, MD, Himanshu J. Patel, MD, G. Michael Deeb, MD, Bo Yang, MD, PhD

“…The ABT group had significantly less sepsis, acute renal failure requiring dialysis, reintubation, and shorter intubation times and postoperative lengths of stay. …”
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Increased cardiovascular risks and mortality in prurigo nodularis: a global cohort studyResearch in context by Henning Olbrich, Khalaf Kridin, Gema Hernández, Henner Zirpel, Christian D. Sadik, Patrick Terheyden, Diamant Thaçi, Ralf J. Ludwig, Katharina Boch

“…Despite being limited to the skin, PN was noted to be associated with systemic diseases including diabetes and chronic renal failure. In previous smaller retrospective studies, several cardiac and vascular diseases were found more frequently in patients with PN. …”
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Stenotrophomonas maltophilia Infections from 2007 to 2011 by Aslıhan CANDEVİR ULU, Behice KURTARAN, Filiz KİBAR, Ayşe Seza İNAL, Süheyla KÖMÜR, Hasan Salih Zeki AKSU, Yeşim TAŞOVA

“…The most commonly seen underlying conditions were hematogenous malignancies (20.6%), renal failure (10.3%), and diabetes mellitus (10.3%). …”
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VASOplegia is Predicted by Preoperative Platelet-LEucocyte conGlomerate Indices in Cardiac Surgery (VASOPLEGICS): A retrospective single-center study by Rohan Magoon, Ramesh C Kashav, Iti Shri, Souvik Dey, Ashish Walian, Jasvinder K Kohli

“…On univariate analysis, age, diabetes, dialysis-dependent renal failure, preoperative congestive heart failure (CHF), the European System for Cardiac Operative Risk Evaluation (EuroSCORE) II, ejection fraction, NLR, PLR, SII, SIRI, AISI, CPB, and aortic cross clamp (ACC) duration, packed red blood cell (PRBC) transfusion, and time-weighted average blood glucose predicted VS. …”
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Pro-inflammatory cytokines in patients with chronic kidney disease: interleukin-6 in focus by I. T. Murkamilov, K. A. Aitbae, V. V. Fomin, Zh. A. Murkamilova, I. S. Sabirov, Z. R. Rayimzhanov, N. A. Redzhapova, F. A. Yusupov

“…Depending on the value of estimated glomerular filtration rate (eGFR), all the examined patients were divided into two groups: 1st (n = 154) - persons with eGFR &gt; 60 ml/min; 2nd (n = 134) - patients with eGFR &lt; 60 ml/min, i.e. renal failure. CKD was identified when there was evidence of damaged and/or reduced renal function. …”
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Is there an agreement between self-reported medical diagnosis in the CARTaGENE cohort and the Québec administrative health databases? by Yves Payette, Cristiano Soares de Moura, Catherine Boileau, Sasha Bernatsky, Nolwenn Noisel

“…Results Agreement between self-reported data and AHD across diseases ranged from kappa of 0.09 for chronic renal failure to 0.86 for type 2 diabetes. Sensitivity of self-reported data was higher than 50% for 14 out of the 31 medical conditions studied, especially for myocardial infarction (88.62%), breast cancer (86.28%), and diabetes (85.06%). …”
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MITRAL ANNULAR CALCIFICATION IN ELDERLY PATIENTS. CLINICAL AND ECHOCARDIOGRAPHIC CHARACTERISTICS by N. S. Chipigina, G. M. Urvacheva, N. A. Shostak, I. V. Zhitareva, I. Yu. Zhitomirskaya

“…To study the clinical and echocardiographic characteristics of the cardiovascular system in patients with MAC aged 65 and older without diabetes mellitus and renal failure. Material and methods. Study included 100 patients with MAC, consecutively identified by 2D transthoracic echocardiography performed with relation to cardiovascular disease symptoms in 910 outpatients aged 65 years or older; the comparison group included 65 of consecutively studied patients without MAC. …”
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Preventive Impella^® Support in High-Risk Patients Undergoing Cardiac Surgery by Kálmán Benke, Edina Korça, Anniek Boltjes, Roland Stengl, Britt Hofmann, Meradjoddin Matin, Katharina Krohe, Yuliana Yakobus, Jens Michaelsen, Levan Khizaneishvili, Gábor Szabó, Gábor Veres

“…The duration of Impella support was 4 (3–7.8) days and the 30-day survival rate was 92.85%. Acute renal failure occurred in four patients who were dialyzed on average for 1.2 ± 0.7 days. …”
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Racial Disparities in Surgery by Arash Azin, MD, Dhruvin H. Hirpara, MD, Sachin Doshi, MD, MEng, Tyler R. Chesney, MD, MSc, Fayez A. Quereshy, MD, MBA, Sami A. Chadi, MD, MSc

“…Black race was associated with increased risk of re-intubation (OR = 1.33, 95% CI 1.21–1.48, P < 0.001), pulmonary embolism (OR = 1.55, 95% CI 1.40–1.71, P < 0.001), failure to wean from ventilator for >48 hours (OR = 1.14, 95% CI 1.02–1.29, P < 0.001), progressive renal insufficiency (OR = 1.63, 95% CI 1.43–1.86, P < 0.001), acute renal failure (OR = 1.39, 95% CI 1.16–1.66, P < 0.001), cardiac arrest (OR = 1.47, 95% CI 1.24–1.76 P < 0.001), bleeding requiring transfusion (OR = 1.39, 95% CI 1.34–1.43, P < 0.001), DVT/thrombophlebitis (OR = 1.24, 95% CI 1.14–1.35, P < 0.001), and sepsis/septic shock (OR = 1.09, 95% CI 1.03–1.15, P < 0.001). …”
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