Cardiac intensive care unit: where we are in 2023 by Amine Bouchlarhem, Amine Bouchlarhem, Zakaria Bazid, Zakaria Bazid, Nabila Ismaili, Nabila Ismaili, Nabila Ismaili, Noha El Ouafi, Noha El Ouafi, Noha El Ouafi

“…Since acute cardiovascular disease is not limited to the management of acute coronary syndromes and includes other emergencies such as severe arrhythmias, acute heart failure, cardiogenic shock, high-risk pulmonary embolism, severe conduction disorders, and post-implantation monitoring of percutaneous valves, as well as other non-cardiac emergencies, such as septic shock, severe respiratory failure, severe renal failure and the management of cardiac arrest after resuscitation, the conversion of coronary intensive care units into cardiac intensive care units represented an important priority. …”
Get full text

Study on the mechanism of Amygdalus mongolica oil anti-renal fibrosis based on metabolomics and transcriptomics by Haimei Hao, Wanfu Bai, Hongbing Zhou, Jia Wang, Zhanjun Yang, Min Qiu, Hong Chang, Songli Shi

“…Renal fibrosis (RF) precedes all kidney diseases, and eventually progresses to end-stage renal failure. It is one of the main pathological manifestations of chronic kidney disease (CKD), which seriously affects the patients’ quality of life. …”
Get full text

The effect of obesity on the outcome of thoracic endovascular aortic repair: a systematic review and meta-analysis by Jiajun Li, Yucong Zhang, Haijun Huang, Yongzhi Zhou, Jing Wang, Min Hu

“…However, the associations between obesity and overall complications (OR = 2.41, 95% CI [0.84–6.93], p = 0.10) and specific complications were all insignificant, including stroke (OR = 1.39, 95% CI [0.56–3.45], p = 0.48), spinal ischemia (OR = 0.97, 95% CI [0.64–1.47], p = 0.89), neurological complications (OR = 0.13, 95% CI [0.01–2.37], p = 0.17), endoleaks (OR = 1.02, 95% CI [0.46–2.29], p = 0.96), wound complications (OR = 0.91, 95% CI [0.28–2.96], p = 0.88), and renal failure (OR = 2.98, 95% CI [0.92–9.69], p = 0.07). …”
Get full text

Plasma Proenkephalin and Poor Long-Term Outcome in Renal Transplant Recipients by Lyanne M. Kieneker, MSc, Oliver Hartmann, MSc, Joachim Struck, PhD, Andreas Bergmann, PhD, Ron T. Gansevoort, MD, PhD, Michel M. Joosten, PhD, Else van den Berg, MD, PhD, Rudolf A. de Boer, MD, PhD, Stephan J.L. Bakker, MD, PhD

“…Proenkephalin (pro-ENK), a stable and reliable surrogate marker for unstable enkephalins, was found to be associated with acute kidney injury and chronic renal failure in previous studies. We aimed to investigate whether pro-ENK is linked to chronic kidney injury and poor long-term outcome in renal transplant recipients (RTR). …”
Get full text

An ultrasound-based femoral artery calcification score by Ethan Maahs, BA, Andrew Schwartz, BA, Alexa Berezowitz, BA, Sean Davis, BA, Raul J. Guzman, MD

“…US-based calcification scores were increased in patients with diabetes, renal failure, and the presence of chronic limb threatening ischemia similar to CT-based femoral calcification. …”
Get full text

Maternal outcomes of pre-eclampsia with severe features and its determinants at Abebech Gobena Mothers and Childrens Health and Saint Peter’s Specialized Hospital, Addis Ababa, Eth... by Mesfin Tadese, Wogene Asefa Damesa, Gebeyehu Shumet Solomon, Getu Engida Wakie, Saba Desta Tessema, Agizew Endale

“…Binary logistic regression analysis was run to identify predictors of maternal outcome.Setting Two hospitals in Addis Ababa, Ethiopia.Participants 348 pregnant women with PEWSF were included.Outcome measures Unfavourable maternal outcome was defined as mothers with PEWSF that develop at least one complication, that is, eclampsia, abruption placenta, Haemolysis, Elevated Liver Enzymes and Low Platelet Count (HELLP) syndrome, acute renal failure, disseminated intravascular coagulation, cardiac failure, stroke, postpartum haemorrhage, pulmonary oedema and death.Results The overall prevalence of unfavourable maternal outcomes was 33.9% (N=118) (95% CI=28.7 to 38.8). …”
Get full text

Identifying functional subtypes of IgA nephropathy based on three machine learning algorithms and WGCNA by Hongbiao Ren, Wenhua Lv, Zhenwei Shang, Liangshuang Li, Qi Shen, Shuai Li, Zerun Song, Xiangshu Cheng, Xin Meng, Rui Chen, Ruijie Zhang

“…Abstract Background IgA nephropathy (IgAN) is one of the most common primary glomerulonephritis, which is a significant cause of renal failure. At present, the classification of IgAN is often limited to pathology, and its molecular mechanism has not been established. …”
Get full text

Rapid Efficacy of Gemtuzumab Ozogamicin in Refractory AML Patients with Pulmonary and Kidney Failure by Daniil Zaytsev, Larisa Girshova, Vladimir Ivanov, Irina Budaeva, Dmitri Motorin, Renat Badaev, Julia Mirolubova, Evgeni Grobovenko, Tamara Chitanava, Ekaterina Zaykova, Julia Alexeeva, Andrey Zaritskey

“…Conclusions: Gemtuzumab ozogamicin therapy appeared to be safe and highly efficacious in relapsed/refractory AML patients with organ dysfunction, like pulmonary or renal failure and poor performance status, and may contribute to rapid recovery from organ failures.…”
Get full text

Saponins from Panax notoginseng ameliorate steroid resistance in lupus nephritis through regulating lymphocyte-derived exosomes in mice by Jia Chen, Jia Chen, Qingyun Zhou, Ying Lu

“…Lupus nephritis (LN) is the most common and severe type of organ damage and an important primary disease in end-stage renal failure in patients with systemic lupus erythematosus (SLE). …”
Get full text

Patients’ Pharmacogenetic Characteristics and the Risk of Adverse Reactions to Non-Steroidal Anti-Inflammatory Drugs: Clinical Cases by A. S. Zhiryakova, N. P. Denisenko, A. V. Kryukov, K. A. Akmalova, S. N. Tuchkova, K. B. Mirzaev, D. A. Sychev

“…The first clinical case demonstrates a neurosurgical patient with spondylodiscitis who showed signs of renal failure associated with ketorolac administration during 13 days of inpatient treatment. …”
Get full text

Underutilization of left heart catheterization in kidney transplant patients presenting with non-ST segment elevation myocardial infarction by Ahmad Mustafa, Samer Asmar, Chapman Wei, John Afif, Shahkar Khan, Taqi Rizvi, Radu Grovu, Mitchell Weinberg, Suzanne El-Sayegh

“…Outcomes included left heart catheterization rates, mortality, arrhythmias, acute kidney injury/acute renal failure (AKI/ARF), and extended length of hospital stay (ELOS) (>72 h). …”
Get full text

The Relationship between the Incidence of Postoperative Cognitive Dysfunction and Intraoperative Regional Cerebral Oxygen Saturation after Cardiovascular Surgery: A Systematic Revi... by Luchen Wang, Zekun Lang, Haoyu Gao, Yanxiang Liu, Huishu Dong, Xiaogang Sun

“…The secondary outcomes were length of hospital stay, length of intensive care unit (ICU) stay, length of mechanical ventilation, length of cardiopulmonary bypass, and other major postoperative outcomes such as renal failure, infection, arrhythmia, hospital mortality, and stroke. …”
Get full text

Acute Aortic Dissection in Young Adult Patients: Clinical Characteristics, Management, and Perioperative Outcomes by Shuai Zhu, Tie Zheng, Zhi-Yu Qiao, Li Chen, Jia-Fu Ou, Wei-Gang Fang, Cheng-Nan Li, Lei Chen, Wei-Guo Ma, Jun Zheng, Yong-Min Liu, Li-Zhong Sun, Xue-Jun Sun, Jun-Ming Zhu

“…Typical complications (central nervous system complications, spinal cord ischemia, myocardial ischemia/infarction, mesenteric ischemia/infarction and acute renal failure) were seen in a small portion of treated patients during perioperative period. …”
Get full text

Preventive effects of the Rehmannia glutinosa Libosch and Cornus officinalis Sieb herb couple on chronic kidney disease rats via modulating the intestinal microbiota and enhancing... by Ling Wang, Ling Wang, Jin-Hui Zhu, Jin-Hui Zhu, Xiao-Dan Jiang, Xiao-Dan Jiang, Zhen-Xiang Ma, Zhen-Xiang Ma, Jin-Hua Tao, Jin-Hua Tao, Jin-Hua Tao

“…At present, modern medicine still lacks an ideal treatment method for this disease, while TCM has accumulated rich clinical experience in the treatment of CKD, which can effectively improve renal function and delay renal failure, and has unique advantages. RC is widely used in clinical practice to treat CKD, especially the “Kidney-Yin” deficiency syndrome. …”
Get full text

Association of timing of percutaneous left ventricular assist device insertion with outcomes in patients undergoing cardiac surgeryCentral MessagePerspective by Jean-Luc A. Maigrot, BS, Randall C. Starling, MD, MPH, Ziad Taimeh, MD, Michael Z.Y. Tong, MD, MBA, Edward G. Soltesz, MD, MPH, Aaron J. Weiss, MD, PhD

“…Postoperative pVAD insertion was associated with increased rates of gastrointestinal bleeding (pre: 2.2%, intra: 3.0%, and post: 7.4%; P = .01), renal failure (pre: 10%, intra: 9.2%, and post: 17%; P = .01), and prolonged ventilation (pre: 44%, intra: 41%, and post: 54%; P = .02). …”
Get full text

Multicolored MIS-C, a single-centre cohort study by Petra Varga, András Balajthy, Erika Biró, Bernadett Bíró, Zsolt Reiger, Edit Szikszay, Gábor Mogyorósy, Rita Káposzta, Tamás Szabó

“…ICU admission was more likely in patients with shortness of breath, renal failure (AKI) and patients with significantly increased concentrations of ferritin, D-dimer, INR and significantly milder increase concentration of fibrinogen. …”
Get full text

Interhospital variability in failure to rescue rates following aortic valve surgeryCentral MessagePerspective by Tyler M. Bauer, MD, Michael Pienta, MD, MS, Xiaoting Wu, PhD, Eric J. Lehr, MD, PhD, Glenn J.R. Whitman, MD, Robert S. Kramer, MD, James Brevig, MD, Francis D. Pagani, MD, PhD, Donald S. Likosky, PhD

“…Postoperative complications were defined as major (stroke, renal failure, reoperation, prolonged ventilation, sternal infection) and overall (major plus 14 other morbidities). …”
Get full text

Phenobarbital ameliorates hyperglycemia-induced angiogenesis in diabetic nephropathy-possible intervention at the HIF-1α/VEGF axis by M. M. Mohammed, S. R. A. Rehim, A. M. M. Okasha, H. El-Mezayen, D. G. A. N. Mohammed, W. Gomaa, F. Mourad, E. G. Ayad

“…Hyperglycemia contributes to a cascade of inflammatory responses in kidneys that result in the development of renal hypoxia and angiogenesis with subsequent chronic renal failure. As the hypoxia-inducible factor-1α (HIF-1α)/vascular endothelial growth factor (VEGF) axis is a key pathway for neovascularization, the inhibition of this axis is a target for renal angiogenesis therapy. …”
Get full text

Development and validation of a predictive model for end-stage renal disease risk in patients with diabetic nephropathy confirmed by renal biopsy by Lulu Sun, Jin Shang, Jing Xiao, Zhanzheng Zhao

“…The outcome was defined as a fatal or nonfatal ESRD event (peritoneal dialysis or hemodialysis for ESRD, renal transplantation, or death due to chronic renal failure or ESRD). The dataset was randomly split into development (75%) and validation (25%) cohorts. …”
Get full text

Derivation and Validation a Risk Model for Acute Kidney Injury and Subsequent Adverse Events After Cardiac Surgery: A Multicenter Cohort Study by Zhang H, Yu M, Wang R, Fan R, Zhang K, Chen W, Chen X

“…Subsequent adverse events included mid-term outcomes: death from all causes and major adverse kidney events (defined as composite outcome of death from renal failure, dialysis, and advanced chronic kidney disease).Results: Acute kidney injury occurred in 3237 (27.6%) patients. …”
Get full text