The combination effect of meropenem/sulbactam/polymyxin-B on the pharmacodynamic parameters for mutant selection windows against carbapenem-resistant Acinetobacter baumannii by Jiayuan Zhang, Shuo Diao, Yanfei Liu, Hongxiang Wang, Yuwei Liu, Shixing Zhu, Kun Feng, Xiaoqian Tang, Charles Oo, Peijuan Zhu, Zhihua Lv, Zhihua Lv, Mingming Yu, Mingming Yu, Sherwin K. B. Sy, Yuanqi Zhu

“…Subsequent corresponding equivalent exposure regimens would depend on the extent of renal failure. The overall results indicate that combination antibiotics consisting of sulbactam/meropenem/polymyxin-B can confer potential efficacy against A. baumannii harboring OXA-23, and reduce the opportunity for bacteria to develop further resistance. …”
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Update on the Classification and Pathophysiological Mechanisms of Pediatric Cardiorenal Syndromes by Giorgia Ceravolo, Tommaso La Macchia, Caterina Cuppari, Valeria Dipasquale, Antonella Gambadauro, Celeste Casto, Maria Domenica Ceravolo, Maricia Cutrupi, Maria Pia Calabrò, Paola Borgia, Gianluca Piccolo, Alessio Mancuso, Remo Albiero, Roberto Chimenz

“…There are at least five known subtypes of CRS, based on the severity of clinical features and the degree of heart/renal failure. The fourth subtype (cardiorenal syndrome type 4 (CRS4)) is characterized by a primary chronic kidney disease (CKD), which in turn leads to a decreased cardiac function. …”
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Detam 1 black soybean against cisplatin-induced acute ren failure on rat model via antioxidant, antiinflammatory and antiapoptosis potential by Wahyu Widowati, Sijani Prahastuti, Meilinah Hidayat, Stella Tinia Hasianna, Roro Wahyudianingsih, The Fransiska Eltania, Alya Mardhotillah Azizah, Jenifer Kiem Aviani, Mawar Subangkit, Rr Anisa Siwianti Handayani, Hanna Sari Widya Kusuma

“…EEBS has potential to improve acute renal failure condition through inflammatory suppression and renal function improvement.…”
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Tazobactam/ceftolozane and tobramycin combination therapy in extensively drug-resistant Pseudomonas aeruginosa infections in severe burn injury: a case report by Yuta Ibe, Ryuichiro Kakizaki, Hirotoshi Inamura, Tomoyuki Ishigo, Yoshihiro Fujiya, Hiroyuki Inoue, Shuji Uemura, Satoshi Fujii, Satoshi Takahashi, Eichi Narimatsu, Masahide Fukudo

“…The patient had acute renal failure, and it was difficult to increase the dose of MEPM and AMK, respectively. …”
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Vascular cognitive impairments in chronic kidney disease by I. V. Rogova, V. V. Fomin, I. V. Damulin, E. G. Minakova, O. Yu. Selivanova, Yu. A. Petleva

“…Objective: to study the specific features of development of cognitive impairments (CIs), the role of traditional cardiovascular risk factors and renal failure-induced factors in patients with Stages I–IV chronic kidney disease (CKD) and to assess an association of CIs with the signs of vascular wall remodeling in them. …”
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Potential benefits of palliative care for polysymptomatic patients with late-stage nonmalignant disease in Taiwan by Yu-Shin Hung, Chun-Hao Chen, Kun-Yun Yeh, Hung Chang, Yun-Chin Huang, Chen-Ling Chang, Wei-Shan Wu, Hai-Pei Hsu, Jin-Chen Lin, Wen-Chi Chou

“…Methods: We retrospectively analyzed 115 patients without cancer hospitalized in a community hospital in Taiwan: 61 had organic brain disease, 31 had chronic obstructive pulmonary disease, 17 had chronic renal failure, 14 had congestive heart failure, 12 had liver cirrhosis, and 20 had multiple illnesses. …”
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Clinical and laboratory characteristics of patients with COVID-19 and concomitant type 2 diabetes by T. Yu. Demidova, K. G. Lobanova, S. N. Perekhodov, M. B. Antsiferov, O. Sh. Oynotkinova

“…The main cause of death from COVID-19 were complications: acute respiratory distress syndrome, sepsis, acute renal failure, thrombotic events.…”
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Isoflavone daidzein ameliorates renal dysfunction and fibrosis in a postmenopausal rat model: Intermediation of angiotensin AT1 and Mas receptors and microRNAs 33a and 27a by Majid Askaripour, Hamid Najafipour, Shadan Saberi, Saleh Yazdani, Saeideh Jafarinejad-Farsangi, Soodeh Rajabi, Elham Jafari, Paul Proost, Sofie Struyf, Fariba Poosti

“…The fractional urine excretion of sodium (FENa+) and potassium (FEK+), renal failure index (RFI), renal interstitial fibrosis (RIF index), glomerulosclerosis, miR-33a, and miR-27a expressions and their target genes were analyzed. …”
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Incidence and Risk Factors for <i>Clostridioides difficile</i> Infections in Non-COVID and COVID-19 Patients: Experience from a Tertiary Care Hospital by Ljiljana Markovic-Denic, Vladimir Nikolic, Borislav Toskovic, Marija Brankovic, Bogdan Crnokrak, Viseslav Popadic, Aleksandra Radojevic, Dusan Radovanovic, Marija Zdravkovic

“…The HA-CDI predictors in the non-COVID patients were older age (<i>p</i> = 0.017), advanced-stage renal failure (<i>p</i> = 0.005), chemotherapy (<i>p</i> = 0.003), and a low albumin level (0.005). (4) Conclusion: Higher incidence rates of HAI-CDIs in COVID-19 patients did not occur due to reduced infection control precautions and hygiene measures but due to antibiotic therapy and therapy with other drugs used during the pandemic.…”
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Late-onset neutropenia induced by anti-B cell therapy with rituximab in patients with ANCA-associated systemic vasculitis by T. V. Beketova, I. Yu. Popov, V. V. Babak

“…A lethal outcome was documented in 5 (31.2%) of 16 cases of LON (1 with MPA, 3 with GPA, and 1 with EGPA) on average 2 (1.5–9) months after the 1st course of RTM, at the same time, in 4 patients LON was complicated by pneumonia, including 2 with septic shock, in another 1 case LON was combined with the development of acute myocardial infarction and progression of chronic renal failure. Overall mortality among 140 patients with ANCA-SV treated with RTM was 11.4%, while in cases with a fatal outcome, the frequency of LON reached 31.2%.Conclusion. …”
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Cryptococcosis in Southern China: Insights from a Six-Year Retrospective Study in Eastern Guangdong by Bilal H, Zhang D, Shafiq M, Khan MN, Chen C, Khan S, Wang Q, Cai L, Awais M, Hu H, Zeng Y

“…A statistically significant difference was reported for chronic renal failure, and anemia (p < 0.05) persisted in cases of three infection types. …”
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Hypertriglyceridemia Is Associated with More Severe Histological Glomerulosclerosis in IgA Nephropathy by Won Jung Choi, Yu Ah Hong, Ji Won Min, Eun Sil Koh, Hyung Duk Kim, Tae Hyun Ban, Young Soo Kim, Yong Kyun Kim, Seok Joon Shin, Seok Young Kim, Chul Woo Yang, Yoon-Kyung Chang

“…Hypertriglyceridemia (HTG) is one factor contributing to atherosclerosis and is a common complication of renal failure. HTG is a significant risk factor for decreased renal function in patients with IgAN. …”
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Are Sutureless and Rapid-Deployment Aortic Valves a Serious Alternative to TA-TAVI? A Matched-Pairs Analysis by Sameer Al-Maisary, Mina Farag, Willem Hendrik Te Gussinklo, Jamila Kremer, Sven T. Pleger, Florian Leuschner, Matthias Karck, Gabor Szabo, Rawa Arif

“…The logistic EuroSCORE was similar (19 ± 12 vs. 17 ± 10; <i>p</i> = 0.257). Postoperative renal failure (<i>p</i> = 0.087) and cerebrovascular accidents (<i>p</i> = 0.315) were without significant difference. …”
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Phenotypic Disease Network-Based Multimorbidity Analysis in Idiopathic Cardiomyopathy Patients with Hospital Discharge Records by Lei Wang, Ye Jin, Jingya Zhou, Cheng Pang, Yi Wang, Shuyang Zhang

“…Finally, according to the result of ARM, the comorbidities and comorbidity patterns of heart failure include diabetes mellitus and metabolic disorder, sleeping disorder, renal failure, liver, and circulatory diseases. Conclusions: The main cause of the comorbid load is aging. …”
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اعتلال الأعصاب السكري by عيسى لايقة, منيف مرعي, هيثم ريحان

“…Results: At the end of the practical study, after ruling out causes of neuropathy (chronic renal failure, hypothyroidism, vitamin B12 deficiency, Gamma pathic neuropathy, amyloidosis para neoplastic neuropathy) by doing suitable tests. …”
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Hyperthermic Intrathoracic Chemotherapy (HITOC) after Cytoreductive Surgery for Pleural Malignancies—A Retrospective, Multicentre Study by Michael Ried, Julia Kovács, Till Markowiak, Karolina Müller, Gunnar Huppertz, Michael Koller, Hauke Winter, Laura V. Klotz, Rudolf Hatz, Julia Zimmermann, Bernward Passlick, Severin Schmid, Mohamed Hassan, Martin E. Eichhorn, Hans-Stefan Hofmann

“…The risk for postoperative renal failure is dependent on the intrathoracic cisplatin dosage but was within an acceptable range.…”
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Short-term outcomes of Ozaki procedure: a multicenter study by I. I. Chernov, S. T. Enginoev, R. N. Komarov, V. V. Bazylev, D. G. Tarasov, K. B. Kadyraliev, D. S. Tungusov, A. V. Arutyunyan, A. V. Chragyan, P. A. Batrakov, A. M. Ismailbaev, B. M. Tlisov, А. Weymann, M.B.O. Sá Pompeu, K. Zhigalov

“…Thirteen (1,8%) patients received a pacemaker. Acute renal failure was recorded in 4 (0,5%) patients, stroke — in 3 (0,4%), and sternal infection — in 10 (1,4%).Conclusion. …”
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Progression of distal aorta after endovascular fenestration/stenting in acute type A aortic dissection with malperfusion syndromeCentral MessagePerspective by Rana-Armaghan Ahmad, BS, Felix Orelaru, MD, Nathan Graham, BS, Marc Titsworth, BS, Katelyn Monaghan, BS, Xiaoting Wu, PhD, Karen M. Kim, MD, Shinichi Fukuhara, MD, Himanshu Patel, MD, G. Michael Deeb, MD, Bo Yang, MD, PhD

“…Results: Compared with the no malperfusion syndrome group, the malperfusion syndrome group had more patients with acute renal failure (60% vs 4.3%, P < .001). Both groups had similar aortic root and arch procedures. …”
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The importance of serum immunoglobulin free light chain assessment for predicting outcome in patients with newly diagnosed multiple myeloma in real clinical practice by N. V. Skvortsova, I. B. Kovynev, K. V. Halzov, T. I. Pospelova

“…The values of the ratio κ / λ FLC &lt;0.04 or&gt; 65, as well as the concentration of FLC-κ and FLC-λ are higher than the median obtained in the whole group (FLC-κ ≥702 mg / L and FLC-λ ≥493.2 mg / L), correlate with known factors of poor prognosis for MM (with a high concentration of β2‑microglobulin (&gt;3.5 mg / L) (r = 0.461; p &lt;0.001), plasma cell bone marrow infiltration &gt;60 % (r = 0.420; p &lt;0.001), renal failure (creatinine &gt;177 μmol / L) (r = 0.380; p = 0.002), and also with high lactate dehydrogenase activity (&gt;450 U / L) (r = 0.520; p &lt;0.001) and is associated with poor outcomes. …”
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ACTIVITY MODULATION OF VARIOUS NITRIC OXIDE SYNTASES AS AN APPROACH TO ENDOTHELIAL DYSFUNCTION THERAPY by D. V. Kurkin, E. E. Abrosimova, D. A. Bakulin, N. S. Kovalev, M. A. Dubrovina, A. V. Borisov, A. V. Strygin, E. I. Morkovin, I. N. Tyurenkov

“…As a vasodilator, nitric oxide may be a unique therapeutic agent for the treatment of hypertension and, as a result, renal failure and left ventricular hypertrophy.The aim of the article is to analyze the literature data on possible ways of modulating the activity of various nitric oxide synthases as an approach to the treatment of endothelial dysfunction.Materials and methods. …”
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