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4741
A 3D In Vivo Model for Studying Human Renal Cystic Tissue and Mouse Kidney Slices
Published 2022-07-01“…(1) Background: Autosomal dominant polycystic kidney disease (ADPKD) is a frequent monogenic disorder that leads to progressive renal cyst growth and renal failure. Strategies to inhibit cyst growth in non-human cyst models have often failed in clinical trials. …”
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4742
Presenting Symptoms in Newly Diagnosed Myeloma, Relation to Organ Damage, and Implications for Symptom-Directed Screening: A Secondary Analysis from the Tackling Early Morbidity an...
Published 2023-06-01“…Vertebral fractures are under-recognised as pathological and are the predominant irreversible organ damage (27% of patients), impacting the performance status (PS) and associated with back pain (odds ratio (OR) 6.14 [CI 4.47–8.44]), bone disease (OR 3.71 [CI 1.88–7.32]) and age >65 years (OR 1.58 [CI 1.15–2.17]). Renal failure is less frequent and associated with gastrointestinal symptoms (OR 2.23 [CI1.28–3.91]), age >65 years (OR 2.14 [CI1.28–3.91]) and absence of back pain (OR 0.44 [CI 0.29–0.67]). …”
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4743
Pulmonary hypertension as a risk assessment factor for unfavorable outcome in patients with COVID-19
Published 2020-12-01“…In group 3, acute renal failure and systemic inflammatory response syndrome developed significantly more often than in group 1.Conclusion. …”
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4744
Immunogenicity and safety of SARS-CoV-2 vaccine in hemodialysis patients: A systematic review and meta-analysis
Published 2022-09-01“…Dialysis patients may experience various adverse events after vaccination; however, the incidence of malignant events is very low, and no reports of death or acute renal failure after vaccination are available, indicating that vaccine regimens may be necessary.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/display_record.asp?…”
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4745
Efficiency of lenalidomide, bortezomib and prednisone (RVP) in patients with newly diagnosed multiple myeloma
Published 2019-04-01“…Nine (23.0 %) patients had renal failure, requiring the start of renal replacement therapy. …”
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4746
Kinase Inhibition in Multiple Myeloma: Current Scenario and Clinical Perspectives
Published 2022-08-01“…The accumulation of this production, both cells themselves and of the immunoglobulins, causes a series of problems for the patient, of a systemic and local nature, such as blood hyperviscosity, renal failure, anemia, bone lesions, and infections due to compromised immunity. …”
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4747
Clinical, epidemiological, and mycological features of patients with candidemia: Experience in two tertiary referral centers in Iran
Published 2022-09-01“…The most common underlying disease was sepsis (48%) followed by malignancy (46%), renal failure/dialysis (44%), and hypertension (40%). …”
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4748
Abstract Number ‐ 190: Acute Ischemic Stroke patients post Endovascular Thrombectomy complicated by gastrointestinal bleeding have worst clinical outcomes
Published 2023-03-01“…Furthermore, the GI bleed group had the following risk factors that were statistically significant: history of atrial fibrillation and chronic renal failure (46% vs 37.2% and 21.8% vs 15.1%, respectively). …”
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4749
Vascular wall microenvironment: exosomes secreted by adventitial fibroblasts induced vascular calcification
Published 2023-09-01“…Abstract Vascular calcification often occurs in patients with chronic renal failure (CRF), which significantly increases the incidence of cardiovascular events in CRF patients. …”
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4750
Plasma Drug Values of DOACs in Patients Presenting with Gastrointestinal Bleeding: A Prospective Observational Study
Published 2023-08-01“…Clinicians should be more judicious when prescribing dabigatran to the elderly and patients with renal failure. In these patients, dose adjustment, plasma drug monitoring, or substitution with other, more appropriate DOACs should be considered.…”
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4751
Comparison of Early and Late Surgeries after Coronary Stent Implantation in Patients with Normal Preoperative Troponin Level: A Retrospective Study
Published 2023-03-01“…The secondary outcomes were myocardial infarction, stent thrombosis, emergent coronary revascularization, major bleeding (bleeding requiring transfusion or intracranial bleeding), stroke, renal failure, heart failure, or death within 30 days post-operation. …”
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4752
Post-marketing safety of immunomodulatory drugs in multiple myeloma: A pharmacovigilance investigation based on the FDA adverse event reporting system
Published 2022-12-01“…Pneumonia, sepsis, and renal failure are common risk factors for death due to IMiDs. …”
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4753
Emerging Mechanisms and Disease Implications of Ferroptosis: Potential Applications of Natural Products
Published 2022-01-01“…A large body of evidence suggests that ferroptosis is interrelated with various physiological and pathological processes, including tumor progression (neuro)degenerative diseases, and hepatic and renal failure. There is an urgent need for the discovery of novel effective ferroptosis-modulating compounds, even though some experimental reagents and approved clinical drugs have been well documented to have anti- or pro-ferroptotic properties. …”
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4754
Independent Association of 25[OH]D Level on Reduced Glutathione and TNF-α in Patients ‎with Diabetes and/or Hypertension
Published 2022-09-01“…Patients receiving any kind of vitamin D or calcium supplements within the last three months were excluded, as were those with a history of renal failure, cancer, liver, thyroid, or any other chronic inflammatory diseases.Results: In total 424 T2DM and/or hypertensive patients (mean age 55± 12 years) were recruited. …”
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4755
Postoperative atrial fibrillation after thoracic surgery (PoAF): risk factors and outcome
Published 2023-09-01“…Results PoAF occurred in 35/338 (10.4%) patients and was significantly more frequent in older patients, with a best predictive value of 71 years at ROC curve analysis (AUC 0.70, p < 0.001) and in those with chronic renal failure (p = 0.01). The left atrial area was also significantly associated with the risk of PoAF (AUC 0.78, p = 0.000). …”
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4756
Heidihuangwan alleviates renal fibrosis in rats with 5/6 nephrectomy by inhibiting autophagy
Published 2022-09-01“…Renal fibrosis is a common pathway for the progression of various chronic kidney diseases (CKD), and the formation and deterioration will eventually lead to end-stage renal failure, which brings a heavy medical burden to the world. …”
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4757
ITGAM rs1143679 Variant in Systemic Lupus Erythematosus Is Associated with Increased Serum Calcification Propensity
Published 2023-05-01“…There were no differences between the groups in terms of global disease activity, kidney involvement, and chronic renal failure. Complement C3 levels were lower in A/A individuals compared to others (0.6 ± 0.08 vs. 0.9 ± 0.25 g/L; <i>p</i> = 0.02). …”
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4758
The Effect of Warfarin Use on Postoperative Outcomes after Femoral Neck Surgery
Published 2023-02-01“…Risk factors included age, gender, Body Mass Index (BMI) > 30, Atrial Fibrillation (AF), Chronic Heart Failure (CHF), and Chronic Renal Failure (CRF). Postoperative outcomes were also collected at each of the patients’ follow-up visits, including number of hospitalization days, delays to theatre, and mortality rate. …”
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4759
Use of Sorbent Based on Hypercrosslinked Styrene-Divinylbenzene Copolymer With Immobilized LPS-Selective Ligand In Hemoperfusion For Treatment of Patients With Septic Shock
Published 2020-12-01“…During the first day, hemoperfudion caused a rapid decline in APACHE II and SOFA scores, while acute renal failure (estimated by urea and creatinine levels) resolved gradually by day 5. …”
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4760
TIcagrelor in Rotational Atherectomy to Reduce TROPonin Enhancement: The TIRATROP Study, A Randomized Controlled Trial
Published 2023-02-01“…Independent predictors for troponin enhancement were acute coronary syndrome presentation, renal failure, elevated C-Reactive protein and multiple lesions treated with RA. …”
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