N6-Methyladenosine Methylomic Landscape of Ureteral Deficiency in Reflux Uropathy and Obstructive Uropathy by Hua Shi, Hua Shi, Hua Shi, Tianchao Xiang, Tianchao Xiang, Tianchao Xiang, Jiayan Feng, Xue Yang, Xue Yang, Xue Yang, Yaqi Li, Yaqi Li, Yaqi Li, Ye Fang, Ye Fang, Ye Fang, Linan Xu, Linan Xu, Linan Xu, Qi Qi, Qi Qi, Qi Qi, Jian Shen, Liangfeng Tang, Qian Shen, Qian Shen, Qian Shen, Xiang Wang, Hong Xu, Hong Xu, Hong Xu, Jia Rao, Jia Rao, Jia Rao

“…BackgroundCongenital anomalies of the kidneys and urinary tracts (CAKUT) represent the most prevalent cause for renal failure in children. The RNA epigenetic modification N6-methyladenosine (m6A) methylation modulates gene expression and function post-transcriptionally, which has recently been revealed to be critical in organ development. …”
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Monitorization of the effects of spinal anaesthesia on cerebral oxygen saturation in elder patients using near-infrared spectroscopy by Aysegul Kusku, Guray Demir, Zafer Cukurova, Gulay Eren, Oya Hergunsel

“…Objective: Central blockage provided by spinal anaesthesia enables realization of many surgical procedures, whereas hemodynamic and respiratory changes influence systemic oxygen delivery leading to the potential development of series of problems such as cerebral ischemia, myocardial infarction and acute renal failure. This study was intended to detect potentially adverse effects of hemodynamic and respiratory changes on systemic oxygen delivery using cerebral oxymetric methods in patients who underwent spinal anaesthesia. …”
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Candidate microRNAs as prognostic biomarkers in heart failure: A systematic review by Rita Figueiredo, Rui Adão, Adelino F. Leite-Moreira, Jennifer Mâncio, Carmen Brás-Silva

“…Although useful in clinical practice, they have limitations as their expression can be influenced by ventricular function, aging, obesity, renal failure and atrial arrhythmias. MicroRNAs have recently emerged as potential diagnostic and prognostic biomarkers, given that they are related to cell growth, proliferation, differentiation, and metabolism. …”
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Heart Failure and Cardiorenal Syndrome: A Narrative Review on Pathophysiology, Diagnostic and Therapeutic Regimens—From a Cardiologist’s View by Angelos C. Mitsas, Mohamed Elzawawi, Sophie Mavrogeni, Michael Boekels, Asim Khan, Mahmoud Eldawy, Ioannis Stamatakis, Dimitrios Kouris, Baraa Daboul, Oliver Gunkel, Boris Bigalke, Ludger van Gisteren, Saif Almaghrabi, Michel Noutsias

“…In cardiorenal syndrome (CRS), heart failure and renal failure are pathophysiologically closely intertwined by the reciprocal relationship between cardiac and renal injury. …”
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D-dimer, BNP/NT-pro-BNP, and creatinine are reliable decision-making biomarkers in life-sustaining therapies withholding and withdrawing during COVID-19 outbreak by David M. Smadja, David M. Smadja, Benjamin A. Fellous, Guillaume Bonnet, Guillaume Bonnet, Caroline Hauw-Berlemont, Willy Sutter, Willy Sutter, Agathe Beauvais, Agathe Beauvais, Charles Fauvel, Aurélien Philippe, Aurélien Philippe, Orianne Weizman, Delphine Mika, Philippe Juvin, Victor Waldmann, Victor Waldmann, Jean-Luc Diehl, Jean-Luc Diehl, Ariel Cohen, Richard Chocron, Richard Chocron

“…The patients with LST decision had significantly more cardiovascular diseases, such as high blood pressure (72.9 vs. 66.7%, p = 0.02), stroke (19.3 vs. 11.1%, p < 0.001), renal failure (30.4 vs. 17.4%, p < 0.001), and heart disease (22.5 vs. 14.9%, p < 0.001). …”
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Poor Patient and Graft Outcome After Induction Treatment by Antithymocyte Globulin in Recipients of a Kidney Graft After Nonrenal Organ Transplantation by Hoa Le Mai, PhD, Michèle Treilhaud, MD, Shani Leviatan Ben-Arye, PhD, Hai Yu, PhD, Hélène Perreault, PhD, Evelyn Ang, PhD, Katy Trébern-Launay, PhD, Julie Laurent, PhD, Stéphanie Malard-Castagnet, PhD, Anne Cesbron, MD, Thi Van Ha Nguyen, PhD, Sophie Brouard, PhD, Lionel Rostaing, MD, Pauline Houssel-Debry, MD, Christophe Legendre, MD, Sophie Girerd, MD, Michèle Kessler, MD, Emmanuel Morelon, MD, Antoine Sicard, MD, Valérie Garrigue, MD, Georges Karam, MD, Xi Chen, PhD, Magali Giral, MD, Vered Padler-Karavani, PhD, Jean Paul Soulillou, MD

“…Background. End-stage renal failure occurs in a substantial number of patients having received a nonrenal transplantation (NRT), for whom a kidney transplantation is needed. …”
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The Potential of Strawberry, Rome Beauty Apple, and New Combination on Fasting Blood as Supporting Diet Therapy in Patients with Type II Diabetes Mellitus by Niken Yuliwati, Riezky Faisal Nugroho

“…Exclusion criteria were type II DM patients who, based on the doctor's diagnosis, had complications such as gastritis, hypertension, chronic renal failure, heart disease, liver disease, stroke, cancer, patients with consumption of antioxidant supplements. …”
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The role of decoy receptor 3 in inflammation and atherosclerosis in patients with chronic kidney disease and renal transplant patients by Saliha Uysal, Aysun Toker, Kültigin Türkmen, Suat Keskin

“…The aim of our study is to determine the relationship, between serum DcR3 levels and inflammatory markers in patients with renal transplantation, those receiving dialysis treatment and cases with chronic renal failure that did not receive replacement therapy, and to evaluate their correlation with USG findings. …”
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The 5-factor modified frailty index (mFI-5) predicts adverse outcomes after elective anterior cervical discectomy and fusion (ACDF) by Matthew S. Chung, BA, Neil Patel, MD, George Abdelmalek, BA, Daniel Coban, MD, Stuart Changoor, MD, Faisal Elali, BS, Kumar Sinha, MD, Ki Hwang, MD, Arash Emami, MD

“…Rates for superficial surgical site infection (SSI), organ/deep space SSI, pneumonia, progressive renal insufficiency, acute renal failure (ARF), urinary tract infection (UTI), stroke/cardiovascular accident (CVA), cardiac arrest requiring cardiopulmonary resuscitation (CPR), myocardial infarction, bleeding requiring transfusions, deep vein thrombosis/thrombophlebitis, sepsis, septic shock, readmissions, reoperation, and mortality incrementally increased with mFI-5 scores from 0 to 3+. …”
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Cardiopatías congénitas, ¿cómo prepararnos para el trasplante?: Aspectos quirúrgicos by Luz Polo López, Álvaro González Rocafort, Bunty Ramchandani Ramchandani, Juvenal Rey Lois, Raúl Sánchez Pérez, María Jesús Lamas Hernández, Tomasa Centella Hernández, Carlos Labrandero de Lera, Óscar González Fernández, Ángel Aroca Peinado

“…Previous surgeries (p = 0.01), postoperative ECMO (p = 0.007) and hemofiltration for acute renal failure (p = 0.003) are statistically associated with inhospital mortality.Median follow-up: 21 months (IQR: 9-72), 4 late deaths. …”
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The effect of vitamin D and magnesium supplementation on clinical symptoms and serum inflammatory and oxidative stress markers in patients with COVID-19: a structured summary of a... by Nahid Ramezani-Jolfaie, Ebrahim Eftekhar, Mohadese Dadinasab, Zahra Ghaeini Hesarooeyeh, Pooria Pakdaman, Farkhondeh Razmpour, Gholamali Javedan, Mahmood Khayatian, Mehdi Hassani Azad, Parivash Davoodian, Elham Brahimi, Shideh Rafati, Sara Nikoofal-Sahlabadi, Mohammad Mohammadi

“…Patients are excluded if they have any of the following conditions: (1) pregnancy or lactation; (2) taking a daily multivitamin or take a vitamin D or magnesium supplement in the last month; (3) participating in other clinical trials; (4) renal failure or dialysis, severe liver disease or cirrhosis; (5) known diagnosis of hypercalcemia; (6) discharging from the hospital less than 24 h after the start of the intervention; (7) history of kidney stones in the last year; (8) transfer the patient to the ICU; (9) baseline vitamin D levels above 80 ng/ml; (10) baseline magnesium levels above 2.6 mg/dl; and (11) unwillingness of the patient to continue the study. …”
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Clinical utilization of artificial intelligence-based COVID-19 pneumonia quantification using chest computed tomography – a multicenter retrospective cohort study in Japan by Hiromu Tanaka, Tomoki Maetani, Shotaro Chubachi, Naoya Tanabe, Yusuke Shiraishi, Takanori Asakura, Ho Namkoong, Takashi Shimada, Shuhei Azekawa, Shiro Otake, Kensuke Nakagawara, Takahiro Fukushima, Mayuko Watase, Hideki Terai, Mamoru Sasaki, Soichiro Ueda, Yukari Kato, Norihiro Harada, Shoji Suzuki, Shuichi Yoshida, Hiroki Tateno, Yoshitake Yamada, Masahiro Jinzaki, Toyohiro Hirai, Yukinori Okada, Ryuji Koike, Makoto Ishii, Naoki Hasegawa, Akinori Kimura, Seiya Imoto, Satoru Miyano, Seishi Ogawa, Takanori Kanai, Koichi Fukunaga

“…The incidence of critical outcomes (requiring the support of high-flow oxygen or invasive mechanical ventilation or death) and complications during hospitalization (bacterial infection, renal failure, heart failure, thromboembolism, and liver dysfunction) was compared between the groups of pneumonia with high/low-percentage lung lesions, based on AI-based CT quantification. …”
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Dapagliflozin acutely improves kidney function in type 2 diabetes mellitus. The PRECARE study by Elisa Lazzaroni, Maria Elena Lunati, Laura Montefusco, Ida Pastore, Enrica Chebat, Vincenzo Cimino, Paola Silvia Morpurgo, Milena Muratori, Laura Plebani, Andrea Bolla, Antonio Rossi, Luciana Vallone, Alessandra Gandolfi, Camilla Tinari, Francesca D’Addio, Moufida Ben Nasr, Cristian Loretelli, Cristiana Scaranna, Rosalia Bellante, Roberto Manfrini, Fabrizio Muratori, Ivano Franzetti, Emanuela Orsi, Carmine Gazzaruso, Renata Ghelardi, Paolo Desenzani, Stefano Genovese, Angela Girelli, Franco Folli, Cesare Berra, Paolo Fiorina

“…Dapagliflozin has been demonstrated to improve glycemic control, blood pressure, and body weight in type 2 diabetes mellitus (T2D); indeed, it can also reduce the risk of progression to renal failure, of hospitalization for heart failure and of cardiovascular death. …”
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Doença de Moyamoya e anestesia com sevoflurano fora do centro cirúrgico: relato de caso Enfermedad de Moyamoya y anestesia con sevoflurano fuera del centro quirúrgico: relato de ca... by Sheila Braga Machado, Florentino Fernandes Mendes, Adriana de Campos Angelini

“…CASE REPORT: Male child, 13 years old, physical status ASA IV, with Moyamoya disease and neurological sequelae after three previous strokes, chronic renal failure and systemic hypertension admitted for high digestive endoscopy. …”
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Acute liver failure secondary to co-infection of Hepatitis B and HIV by Yajzeel Estevez-López, Alan J. Romero-Sanchez, José E. López-Ruiz

“…In this case, despite having started treatment in the first 24 hours, the patient did not improve and once they present renal failure, renal replacement therapy and management in intensive care should be provided in order to reduce mortality and allow recovery. …”
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The characteristics and outcomes in patients with acute heart failure who used tolvaptan: from KCHF registry by Ryusuke Nishikawa, Takao Kato, Takeshi Morimoto, Hidenori Yaku, Yasutaka Inuzuka, Yodo Tamaki, Erika Yamamoto, Neiko Ozasa, Tomohisa Tada, Hiroki Sakamoto, Yuta Seko, Masayuki Shiba, Yusuke Yoshikawa, Yugo Yamashita, Takeshi Kitai, Ryoji Taniguchi, Moritake Iguchi, Kazuya Nagao, Takafumi Kawai, Akihiro Komasa, Yuichi Kawase, Takashi Morinaga, Mamoru Toyofuku, Yutaka Furukawa, Kenji Ando, Kazushige Kadota, Yukihito Sato, Koichiro Kuwahara, Takeshi Kimura, for the KCHF Study Investigators

“…Patients with tolvaptan use had a longer hospital stay [median (interquartile range): 22 (15–34) days vs. 15 (11–21) days, P < 0.0001] and a higher prevalence of worsening renal failure (47.0% vs. 31.8%, P < 0.0001) and worsening heart failure (24.8% vs. 14.4%, P < 0.0001) than those without. …”
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Catastrophic Antiphospholipid Syndrome by Victoria Bitsadze, Fidan Yakubova, Jamilya Khizroeva, Arina Lazarchuk, Polina Salnikova, Alexander Vorobev, Maria Tretyakova, Natalia Degtyareva, Kristina Grigoreva, Nilufar Gashimova, Margaret Kvaratskheliia, Nataliya Makatsariya, Ekaterina Kudryavtseva, Anna Tomlenova, Jean-Christophe Gris, Ismail Elalamy, Cihan Ay, Alexander Makatsariya

“…CAPS typically develops after infection, trauma, or surgery and begins with the following symptoms: fever, thrombocytopenia, muscle weakness, visual and cognitive disturbances, abdominal pain, renal failure, and disseminated intravascular coagulation. …”
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Triglyceride–glucose index change and chronic kidney disease progression in a Chinese hypertensive population by Chao Yu, Chao Yu, Chao Yu, Chao Yu, Yumeng Shi, Yumeng Shi, Yumeng Shi, Tao Wang, Tao Wang, Tao Wang, Tao Wang, Lingjuan Zhu, Lingjuan Zhu, Lingjuan Zhu, Lingjuan Zhu, Wei Zhou, Wei Zhou, Wei Zhou, Wei Zhou, Huihui Bao, Huihui Bao, Huihui Bao, Huihui Bao, Xiaoshu Cheng, Xiaoshu Cheng, Xiaoshu Cheng, Xiaoshu Cheng

“…The study’s outcome variable was the progression of CKD, defined as follows: for subjects with an estimated glomerular filtration rate (eGFR) ≥60 mL/min, a ≥30% decrease in eGFR with a final follow-up value &lt;60 mL/min; for those with an eGFR &lt;60 mL/min, a ≥50% decrease in eGFR; or terminal renal failure requiring dialysis.ResultsDuring a median follow-up period of 48 months, 1077 patients were diagnosed with CKD progression. …”
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The role of thoracic ultrasonography in the assessment of extravascular lung water and breathlessness by Corcoran, J

“…The third study presented in this thesis assessed the ability of thoracic ultrasound to detect the presence of, and identify real-time changes in extravascular lung water in patients with end-stage renal failure undergoing haemodialysis. Computed tomography was utilized to provide a gold-standard radiologic reference test to correlate with the findings on thoracic ultrasound in this patient population. 30 participants were recruited to this prospective observational study, undergoing a standardised 20-point thoracic ultrasound examination to derive a total lung ultrasound B-line score before, during and after haemodialysis. …”

Case Report: Hyperammonemic Encephalopathy Linked to Ureaplasma spp. and/or Mycoplasma hominis Systemic Infection in Patients Treated for Leukemia, an Emergency Not to Be Missed by Manon Delafoy, Juliette Goutines, Aude-Marie Fourmont, André Birgy, André Birgy, Maryline Chomton, Michaël Levy, Jérôme Naudin, Lara Zafrani, Lara Zafrani, Lou Le Mouel, Karima Yakouben, Aurélie Cointe, Aurélie Cointe, Marion Caseris, Matthieu Lafaurie, Stéphane Bonacorsi, Stéphane Bonacorsi, Françoise Mechinaud, Sabine Pereyre, Sabine Pereyre, Nicolas Boissel, Nicolas Boissel, André Baruchel, André Baruchel

“…One patient had moderate renal failure. Extensive liver and metabolic functions were all normal. …”
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