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Arginine cofactors on the polymerase ribozyme.
Published 2011-01-01“…An RNA polymerase ribozyme was developed previously in the lab but it is not efficient enough for self-replication. …”
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A Faster Triphosphorylation Ribozyme.
Published 2015-01-01“…The resulting ribozyme, TPR1e, contains seven mutations relative to TPR1, displays a previously unidentified duplex that constrains the ribozyme's structure, and reacts at a 24-fold faster rate than the parent ribozyme. …”
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The Application of Ribozymes and DNAzymes in Muscle and Brain
Published 2010-08-01Subjects: Get full text
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Searching for ribozymes with new and improved properties
Published 2007Get full text
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Ribozymes as therapeutic tools for genetic disease.
Published 1998“…The hammerhead ribozyme, one of the smallest ribozymes identified, is able to induce site-specific cleavage of RNA, with ribozyme and substrate being two different oligoribonucleotides with regions of complementarity. …”
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Expanding the limits of the second genetic code with ribozymes
Published 2019-11-01Get full text
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Viroid Replication: Rolling-Circles, Enzymes and Ribozymes
Published 2009-09-01Subjects: Get full text
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Inhibition of telomerase activity by HDV ribozyme in cancers
Published 2011-01-01“…</p> <p>Conclussion</p> <p>HDV ribozyme (g.RZ57) is an effective strategy for gene therapy.…”
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Structure, dynamics, and mechanism of the lead-dependent ribozyme
Published 2011-08-01Get full text
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Computational approaches to the identification of ribozyme target sites.
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Pressure modulates the self-cleavage step of the hairpin ribozyme
Published 2017-03-01“…Studying the reactivity of ribozymes under extreme pressure could provide insights to optimize biocatalytic RNA design. …”
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Emergent properties as by-products of prebiotic evolution of aminoacylation ribozymes
Published 2022-06-01Get full text
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